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Mariachiara Arisi has received honoraria from L\u2019Oreal and Almirall. Manfredo Bruni has served as speaker\/board member for AbbVie, Almirall and Novartis. Maria Esposito has served as speaker\/consultant for AbbVie, Amgen, Almirall, Boehringer-Ingelheim, Eli Lilly, Janssen, Leo Pharma, Novartis, Pfizer, Sanofi-Regeneron and UCB. Piergiacomo Calzavara-Pinton has served on advisory boards, received honoraria for lectures and\/or research grants from Cantabria, La Roche Posay, Abbvie, Novartis, Sanofi, Leo, Galderma, Sun Pharma, Regeneron. Piergiacomo Calzavara-Pinton is an Editorial Board member of Dermatology and Therapy. Piergiacomo Calzavara-Pinton was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. Maria Concetta Fargnoli has served on advisory boards, received honoraria for lectures and\/or research grants from AMGEN, Almirall, Abbvie, Boehringer-Ingelheim, BMS, Galderma, Kyowa Kyrin, Leo Pharma, Pierre Fabre, UCB, Lilly, Pfizer, Janssen, MSD, Novartis, Sanofi-Regeneron and Sunpharma. Cristina Pellegrini, Grazia Linda Artelli, Alice Zola, Benedetta Galli, Carola Roman\u00f2 have nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This study was conducted in accordance with the ethical principles derived from the Declaration of Helsinki of 1964 and its later amendments, with the exception that this trial was retrospectively registered. This study was also conducted in accordance with the ICH statement on good clinical practice and in compliance with local regulatory requirements and was reviewed and approved by the Abruzzo Ethical Committee (C.Et.R.A.) no. 47\/2025. All participants provided written informed consent prior to enrollment in the study. In addition, the patient whose clinical images are presented granted explicit consent for their inclusion and publication in an open-access journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}