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Chac\u00f3n-Mart\u00ednez works for and is a shareholder of Mane Biotech GmbH, and is named as an inventor on patents related to the device evaluated in this study. Gleb Pogorelov and Kin K. Cabral are employed by Mane Biotech GmbH. Tanja Emmler and Werner Voss are employees of Dermatest GmbH, which served as an independent CRO for this study. The authors declare no other competing interests that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study was approved by the International Medical and Dental Ethics Commission (IMDEC study no. 2208293810; Institutional Review Board [IRB] reference no. 2023\/106). The trial was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. All participants provided written informed consent prior to any study-related procedures. This trial was retrospectively registered at ClinicalTrials.gov (NCT06994819; registered 29 May 2025). Participants signed informed consent regarding publishing their data.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}