{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:13:52Z","timestamp":1783941232323,"version":"3.55.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,10,28]],"date-time":"2017-10-28T00:00:00Z","timestamp":1509148800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["25293145"],"award-info":[{"award-number":["25293145"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["15K15227"],"award-info":[{"award-number":["15K15227"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17015018"],"award-info":[{"award-number":["17015018"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["221S0001"],"award-info":[{"award-number":["221S0001"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["221S0002"],"award-info":[{"award-number":["221S0002"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["16H06277"],"award-info":[{"award-number":["16H06277"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["16H06279"],"award-info":[{"award-number":["16H06279"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008817","name":"Ministry of Defense- Japan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008817","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003427","name":"Gout Research Foundation of Japan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003427","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Kawano Masanori Memorial Foundation for Promotion of Pediatrics"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Human Cell"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1007\/s13577-017-0186-6","type":"journal-article","created":{"date-parts":[[2017,10,28]],"date-time":"2017-10-28T02:50:42Z","timestamp":1509159042000},"page":"10-13","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A common variant of MAF\/c-MAF, transcriptional factor gene in the kidney, is associated with gout susceptibility"],"prefix":"10.1007","volume":"31","author":[{"given":"Toshihide","family":"Higashino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Matsuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukinori","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Nakashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiko","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Sakiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Tadokoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiyoshi","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mako","family":"Komatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asahi","family":"Hishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Nakatochi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ooyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Imaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nariyoshi","family":"Shinomiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,10,28]]},"reference":[{"issue":"8","key":"186_CR1","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ng.2352","volume":"44","author":"Y Okada","year":"2012","unstructured":"Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, et al. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet. 2012;44(8):904\u20139.","journal-title":"Nat Genet"},{"issue":"4","key":"186_CR2","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1136\/annrheumdis-2014-206191","volume":"75","author":"H Matsuo","year":"2016","unstructured":"Matsuo H, Yamamoto K, Nakaoka H, Nakayama A, Sakiyama M, Chiba T, et al. Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes. Ann Rheum Dis. 2016;75(4):652\u20139.","journal-title":"Ann Rheum Dis"},{"issue":"12","key":"186_CR3","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/gm118","volume":"1","author":"K Ichida","year":"2009","unstructured":"Ichida K. What lies behind serum urate concentration? Insights from genetic and genomic studies. Genome Med. 2009;1(12):118.","journal-title":"Genome Med"},{"key":"186_CR4","doi-asserted-by":"crossref","first-page":"20148","DOI":"10.1038\/srep20148","volume":"6","author":"M Sakiyama","year":"2016","unstructured":"Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakamura T, Nakayama A, et al. The effects of URAT1\/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout\/hyperuricemia progression. Sci Rep. 2016;6:20148.","journal-title":"Sci Rep"},{"issue":"6","key":"186_CR5","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.ajhg.2008.11.001","volume":"83","author":"H Matsuo","year":"2008","unstructured":"Matsuo H, Chiba T, Nagamori S, Nakayama A, Domoto H, Phetdee K, et al. Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia. Am J Hum Genet. 2008;83(6):744\u201351.","journal-title":"Am J Hum Genet"},{"issue":"25","key":"186_CR6","doi-asserted-by":"crossref","first-page":"10338","DOI":"10.1073\/pnas.0901249106","volume":"106","author":"OM Woodward","year":"2009","unstructured":"Woodward OM, K\u00f6ttgen A, Coresh J, Boerwinkle E, Guggino WB, K\u00f6ttgen M. Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout. Proc Natl Acad Sci USA. 2009;106(25):10338\u201342.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"186_CR7","doi-asserted-by":"crossref","first-page":"5ra11","DOI":"10.1126\/scitranslmed.3000237","volume":"1","author":"H Matsuo","year":"2009","unstructured":"Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Ikebuchi Y, et al. Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population. Sci Transl Med. 2009;1(5):5ra11.","journal-title":"Sci Transl Med."},{"issue":"1","key":"186_CR8","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/art.38884","volume":"67","author":"T Chiba","year":"2015","unstructured":"Chiba T, Matsuo H, Kawamura Y, Nagamori S, Nishiyama T, Wei L, et al. NPT1\/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout. Arthritis Rheumatol. 2015;67(1):281\u20137.","journal-title":"Arthritis Rheumatol"},{"issue":"3","key":"186_CR9","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/art.1780200320","volume":"20","author":"SL Wallace","year":"1977","unstructured":"Wallace SL, Robinson H, Masi AT, Decker JL, McCarty DL, Yu TF. Preliminary criteria for the classification of the acute arthritis of primary gout. Arthritis Rheum. 1977;20(3):895\u2013900.","journal-title":"Arthritis Rheum"},{"issue":"2","key":"186_CR10","first-page":"317","volume":"8","author":"N Hamajima","year":"2007","unstructured":"Hamajima N, J-MICC Study Group. The Japan multi-institutional collaborative cohort study (J-MICC Study) to detect gene-environment interactions for cancer. Asian Pac J Cancer Prev. 2007;8(2):317\u201323.","journal-title":"Asian Pac J Cancer Prev"},{"issue":"4","key":"186_CR11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s13577-013-0073-8","volume":"26","author":"A Nakayama","year":"2013","unstructured":"Nakayama A, Matsuo H, Shimizu T, Ogata H, Takada Y, Nakashima H, et al. Common missense variant of monocarboxylate transporter 9 (MCT9\/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility. Hum Cell. 2013;26(4):133\u20136.","journal-title":"Hum Cell"},{"issue":"1","key":"186_CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13577-013-0081-8","volume":"27","author":"M Sakiyama","year":"2014","unstructured":"Sakiyama M, Matsuo H, Shimizu S, Chiba T, Nakayama A, Takada Y, et al. Common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility. Hum Cell. 2014;27(1):1\u20134.","journal-title":"Hum Cell"},{"issue":"20","key":"186_CR13","doi-asserted-by":"crossref","first-page":"7711","DOI":"10.1073\/pnas.86.20.7711","volume":"86","author":"M Nishizawa","year":"1989","unstructured":"Nishizawa M, Kataoka K, Goto N, Fujiwara KT, Kawai S. v-maf, a viral oncogene that encodes a \u201cleucine zipper\u201d motif. Proc Natl Acad Sci USA. 1989;86(20):7711\u20135.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"186_CR14","doi-asserted-by":"crossref","first-page":"2","DOI":"10.23861\/EJBM20072347","volume":"23","author":"Y Yang","year":"2007","unstructured":"Yang Y, Cvekl A. Large Maf transcription factors: cousins of AP-1 proteins and important regulators of cellular differentiation. Einstein J Biol Med. 2007;23(1):2\u201311.","journal-title":"Einstein J Biol Med"},{"issue":"1","key":"186_CR15","doi-asserted-by":"crossref","first-page":"175","DOI":"10.4239\/wjd.v6.i1.175","volume":"6","author":"M Tsuchiya","year":"2015","unstructured":"Tsuchiya M, Misaka R, Nitta K, Tsuchiya K. Transcriptional factors, Mafs and their biological roles. World J Diabetes. 2015;6(1):175\u201383.","journal-title":"World J Diabetes"},{"issue":"4","key":"186_CR16","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.bbrc.2004.05.222","volume":"320","author":"J Imaki","year":"2004","unstructured":"Imaki J, Tsuchiya K, Mishima T, Onodera H, Kim JI, Yoshida K, et al. Developmental contribution of c-maf in the kidney: distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of c-maf knockout mice kidney and liver. Biochem Biophys Res Commun. 2004;320(4):1323\u20137.","journal-title":"Biochem Biophys Res Commun"},{"issue":"6","key":"186_CR17","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/hmg\/ddg063","volume":"12","author":"MF Lyon","year":"2003","unstructured":"Lyon MF, Jamieson RV, Perveen R, Glenister PH, Griffiths R, Boyd Y, et al. A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding. Hum Mol Genet. 2003;12(6):585\u201394.","journal-title":"Hum Mol Genet"}],"container-title":["Human Cell"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13577-017-0186-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13577-017-0186-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13577-017-0186-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T06:12:33Z","timestamp":1514355153000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13577-017-0186-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,28]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["186"],"URL":"https:\/\/doi.org\/10.1007\/s13577-017-0186-6","relation":{},"ISSN":["1749-0774"],"issn-type":[{"value":"1749-0774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,28]]}}}