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All animal experiments were approved by the Ethics Committee of the Eighth Affiliated Hospital of Sun Yat-sen University (No. 2024-178-01). Animal experiments were performed in accordance with ARRIVE guidelines and U.K. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010\/63\/EU for animal experiments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"75"}}