{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:37:05Z","timestamp":1790231825558,"version":"4.1.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T00:00:00Z","timestamp":1516579200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CEN Case Rep"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1007\/s13730-018-0309-2","type":"journal-article","created":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T15:58:23Z","timestamp":1516636703000},"page":"127-131","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A case of lipoprotein glomerulopathy with a rare apolipoprotein E isoform combined with neurofibromatosis type I"],"prefix":"10.1007","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8485-2929","authenticated-orcid":false,"given":"Satoshi","family":"Takasaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Matsunaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Joh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,1,22]]},"reference":[{"key":"309_CR1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0272-6386(89)80134-9","volume":"13","author":"T Saito","year":"1989","unstructured":"Saito T, Sato H, Kudo K, et al. Lipoprotein glomerulopathy: glomerular lipoprotein thrombi in a patient with hyperlipoproteinemia. Am J Kidney Dis. 1989;13:148\u201353.","journal-title":"Am J Kidney Dis"},{"key":"309_CR2","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1681\/ASN.V85820","volume":"8","author":"S Oikawa","year":"1997","unstructured":"Oikawa S, Matsunaga A, Saito T, et al. Apolipoprotein E Sendai (arginine 145\u00a0\u27f6\u00a0proline): a new variant associated with lipoprotein glomerulopathy. J Am Soc Nephrol. 1997;8:820\u20133.","journal-title":"J Am Soc Nephrol"},{"key":"309_CR3","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1046\/j.1523-1755.1999.00572.x","volume":"56","author":"A Matsunaga","year":"1999","unstructured":"Matsunaga A, Sasaki J, Komatsu T, et al. A novel apolipoprotein E mutation, E2 (Arg25Cys), in lipoprotein glomerulopathy. Kidney Int. 1999;56:421\u20137.","journal-title":"Kidney Int"},{"key":"309_CR4","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1007\/s10157-013-0887-4","volume":"18","author":"T Saito","year":"2014","unstructured":"Saito T, Matsunaga A, Ito K, Nakashima H. Topics in lipoprotein glomerulopathy: an overview. Clin Exp Nephrol. 2014;18:214\u20137.","journal-title":"Clin Exp Nephrol"},{"key":"309_CR5","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1159\/000478902","volume":"7","author":"H Kodera","year":"2017","unstructured":"Kodera H, Mizutani Y, Sugiyama S, et al. A case of lipoprotein glomerulopathy with ApoE Chicago and ApoE (Glu3Lys) treated with fenofibrate. Case Rep Nephrol Dial. 2017;7:112\u201320.","journal-title":"Case Rep Nephrol Dial"},{"key":"309_CR6","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1681\/ASN.V1071590","volume":"10","author":"T Miyata","year":"1999","unstructured":"Miyata T, Sugiyama S, Nangaku M, et al. Apolipoprotein E2\/E5 variants in lipoprotein glomerulopathy recurred in transplanted kidney. J Am Soc Nephrol. 1999;10:1590\u20135.","journal-title":"J Am Soc Nephrol"},{"key":"309_CR7","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1053\/j.ajkd.2005.12.031","volume":"47","author":"R Sam","year":"2006","unstructured":"Sam R, Wu H, Yue L, et al. Lipoprotein glomerulopathy: a new apolipoprotein E mutation with enhanced glomerular binding. Am J Kidney Dis. 2006;47:539\u201348.","journal-title":"Am J Kidney Dis"},{"key":"309_CR8","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0022-2275(20)38690-9","volume":"28","author":"JM Ordovas","year":"1987","unstructured":"Ordovas JM, Litwack-Klein L, Wilson PW, Schaefer MM, Schaefer EJ. Apolipoprotein E isoform phenotyping methodology and population frequency with identification of ApoE1 and ApoE5 isoforms. J Lipid Res. 1987;28:371\u201380.","journal-title":"J Lipid Res"},{"key":"309_CR9","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/S0022-2275(20)39106-9","volume":"37","author":"G Feussner","year":"1996","unstructured":"Feussner G, Scharnagl H, Scherbaum C, et al. Apolipoprotein E5 (Glu212\u00a0\u27f6\u00a0Lys): increased binding to cell surface proteoglycans but decreased uptake and lysosomal degradation in cultured fibroblasts. J Lipid Res. 1996;37:1632\u201345.","journal-title":"J Lipid Res"},{"key":"309_CR10","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0006-291X(90)92336-X","volume":"168","author":"LM Dong","year":"1990","unstructured":"Dong LM, Yamamura T, Yamamoto A. Enhanced binding activity of an apolipoprotein E mutant, APO E5, to LDL receptors on human fibroblasts. Biochem Biophys Res Commun. 1990;168:409\u201314.","journal-title":"Biochem Biophys Res Commun"},{"key":"309_CR11","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0022-2275(20)42076-0","volume":"32","author":"MR Wardell","year":"1991","unstructured":"Wardell MR, Rall SC Jr, Schaefer EJ, Kane JP, Weisgraber KH. Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity. J Lipid Res. 1991;32:521\u20138.","journal-title":"J Lipid Res"},{"key":"309_CR12","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.ejmg.2014.09.001","volume":"57","author":"J Van-Gils","year":"2014","unstructured":"Van-Gils J, Harambat J, Jubert C, et al. Atypical hematologic and renal manifestations in neurofibromatosis type I: coincidence or pathophysiological link? Eur J Med Genet. 2014;57:639\u201342.","journal-title":"Eur J Med Genet"},{"key":"309_CR13","doi-asserted-by":"crossref","first-page":"186","DOI":"10.3904\/kjim.2015.016","volume":"32","author":"JI Hyun","year":"2017","unstructured":"Hyun JI, Min JW, Lee HM, Kim YK, Choi EJ, Song HC. Minimal change nephrotic syndrome showing complete remission after resection of a neurofibroma in a type I neurofibromatosis patient. Korean J Intern Med. 2017;32:186\u20139.","journal-title":"Korean J Intern Med"},{"key":"309_CR14","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/ckj\/sft010","volume":"6","author":"F Afshinnia","year":"2013","unstructured":"Afshinnia F, Vega-Warner V, Killen P. Focal segmental glomerulosclerosis in association with neurofibromatosis type 1: a case report and proposed molecular pathways. Clin Kidney J. 2013;6:208\u201310.","journal-title":"Clin Kidney J"},{"key":"309_CR15","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1681\/ASN.2004121084","volume":"16","author":"M Koshikawa","year":"2005","unstructured":"Koshikawa M, Mukoyama M, Mori K, et al. Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. J Am Soc Nephrol. 2005;16:2690\u2013701.","journal-title":"J Am Soc Nephrol"},{"key":"309_CR16","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1172\/JCI44774","volume":"121","author":"M G\u00f6del","year":"2011","unstructured":"G\u00f6del M, Hartleben B, Herbach N, et al. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest. 2011;121:2197\u2013209.","journal-title":"J Clin Invest"},{"key":"309_CR17","doi-asserted-by":"crossref","first-page":"3899","DOI":"10.1093\/ndt\/gfs329","volume":"27","author":"K Ito","year":"2012","unstructured":"Ito K, Nakashima H, Watanabe M, et al. Macrophage impairment produced by Fc receptor gamma deficiency plays a principal role in the development of lipoprotein glomerulopathy in concert with apoE abnormalities. Nephrol Dial Transplant. 2012;27:3899\u2013907.","journal-title":"Nephrol Dial Transplant"},{"key":"309_CR18","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0165-4608(02)00527-7","volume":"15","author":"T Koga","year":"2002","unstructured":"Koga T, Iwasaki H, Ishiguro M, Matsuzaki A, Kikuchi M. Losses in chromosomes 17, 19, and 22q in neurofibromatosis type 1 and sporadic neurofibromas: a comparative genomic hybridization analysis. Cancer Genet Cytogenet. 2002;15:113\u201320.","journal-title":"Cancer Genet Cytogenet"}],"container-title":["CEN Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13730-018-0309-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-018-0309-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-018-0309-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T00:26:07Z","timestamp":1660350367000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13730-018-0309-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,22]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["309"],"URL":"https:\/\/doi.org\/10.1007\/s13730-018-0309-2","relation":{},"ISSN":["2192-4449"],"issn-type":[{"value":"2192-4449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,22]]}}}