{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:50:48Z","timestamp":1779886248822,"version":"3.53.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T00:00:00Z","timestamp":1547424000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CEN Case Rep"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1007\/s13730-019-00376-6","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T04:50:17Z","timestamp":1547441417000},"page":"119-124","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Anti-mitochondria antibody-related tubulointerstitial nephritis accompanied by severe hypokalemic paralysis"],"prefix":"10.1007","volume":"8","author":[{"given":"Masashi","family":"Morita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshito","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Masuyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachio","family":"Kajimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryota","family":"Haga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Yamanouchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuyuki","family":"Nagatoya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Miwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Yamauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,1,14]]},"reference":[{"key":"376_CR1","first-page":"179","volume":"54","author":"A Schwarz","year":"2000","unstructured":"Schwarz A, Krause PH, Kunzendorf U, Keller F, Distler A. The outcome of acute interstitial nephritis: risk factors for the transition from acute to chronic interstitial nephritis. Clin Nephrol. 2000;54:179\u201390.","journal-title":"Clin Nephrol"},{"key":"376_CR2","doi-asserted-by":"publisher","first-page":"3688","DOI":"10.1681\/ASN.2016101074","volume":"28","author":"N Takahashi","year":"2017","unstructured":"Takahashi N, Saeki T, Komatsuda A, Munemura C, Fukui T, Imai N, Homma N, Hatta T, Samejima KI, Fujimoto T, Omori H, Ito Y, Nishikawa Y, Kobayashi M, Morikawa Y, Fukushima S, Yokoi S, Mikami D, Kasuno K, Kimura H, Nemoto T, Nakamoto Y, Sada K, Sugai M, Naiki H, Yoshida H, Narita I, Saito Y, Iwano M. Tubulointerstitial nephritis with IgM-positive plasma cells. J Am Soc Nephrol. 2017;28:3688\u201398.","journal-title":"J Am Soc Nephrol"},{"key":"376_CR3","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1038\/ki.2010.271","volume":"78","author":"T Saeki","year":"2010","unstructured":"Saeki T, Nishi S, Imai N, Ito T, Yamazaki H, Kawano M, Yamamoto M, Takahashi H, Matsui S, Nakada S, Origuchi T, Hirabayashi A, Homma N, Tsubata Y, Takata T, Wada Y, Saito A, Fukase S, Ishioka K, Miyazaki K, Masaki Y, Umehara H, Sugai S, Narita I. Clinicopathological characteristics of patients with IgG4-related tubulointerstitial nephritis. Kidney Int. 2010;78:1016\u201323.","journal-title":"Kidney Int"},{"key":"376_CR4","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S0039-6257(01)00261-2","volume":"46","author":"JT Mandeville","year":"2001","unstructured":"Mandeville JT, Levinson RD, Holland GN. The tubulointerstitial nephritis and uveitis syndrome. Surv Ophthalmol. 2001;46:195\u2013208.","journal-title":"Surv Ophthalmol"},{"key":"376_CR5","doi-asserted-by":"publisher","first-page":"1660","DOI":"10.1016\/j.jada.2010.08.006","volume":"110","author":"X Ye","year":"2010","unstructured":"Ye X, Maras JE, Bakun PJ, Tucker KL. Dietary intake of vitamin B-6, plasma pyridoxal 5\u2032-phosphate, and homocysteine in Puerto Rican adults. J Am Diet Assoc. 2010;110:1660\u20138.","journal-title":"J Am Diet Assoc"},{"key":"376_CR6","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.celrep.2015.08.063","volume":"13","author":"J Kunisawa","year":"2015","unstructured":"Kunisawa J, Sugiura Y, Wake T, Nagatake T, Suzuki H, Nagasawa R, Shikata S, Honda K, Hashimoto E, Suzuki Y, Setou M, Suematsu M, Kiyono H. Mode of bioenergetic metabolism during B cell differentiation in the intestine determines the distinct requirement for vitamin B1. Cell Rep. 2015;13:122\u201331.","journal-title":"Cell Rep"},{"key":"376_CR7","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/ki.2013.393","volume":"85","author":"T Saeki","year":"2014","unstructured":"Saeki T, Kawano M. IgG4-related kidney disease. Kidney Int. 2014;85:251\u20137.","journal-title":"Kidney Int"},{"key":"376_CR8","doi-asserted-by":"publisher","first-page":"74","DOI":"10.5414\/CNP74074","volume":"74","author":"N Takahashi","year":"2010","unstructured":"Takahashi N, Kimura H, Kawajiri Y, Mikami D, Yamamoto C, Kasuno K, Imai N, Kuroda T, Nishi S, Yamamoto M, Yoshida H. Tubulointerstitial nephritis with IgM-positive plasmacytoid large lymphocyte infiltration in a patient with primary biliary cirrhosis and sj\u00f6gren\u2019s syndrome. Clin Nephrol. 2010;74:74\u201380.","journal-title":"Clin Nephrol"},{"key":"376_CR9","doi-asserted-by":"publisher","first-page":"e41-6","DOI":"10.1053\/j.ajkd.2005.05.021","volume":"46","author":"M Lino","year":"2005","unstructured":"Lino M, Binaut R, No\u00ebl LH, Patey N, Rustin P, Daniel L, Serpaggi J, Varaut A, Vanhille P, Knebelmann B, Gr\u00fcnfeld JP, Fakhouri F. Tubulointerstitial nephritis and Fanconi syndrome in primary biliary cirrhosis. Am J Kidney Dis. 2005;46:e41-6.","journal-title":"Am J Kidney Dis"},{"key":"376_CR10","first-page":"401","volume":"45","author":"T Kodama","year":"1996","unstructured":"Kodama T, Imai H, Wakui H, Ohtani H, Komatsuda A, Miura AB. Tubulointerstitial nephritis with renal tubular acidosis and asymptomatic primary biliary cirrhosis accompanied by antibody to a 52-kDa mitochondrial protein alone. Clin Nephrol. 1996;45:401\u20135.","journal-title":"Clin Nephrol"},{"key":"376_CR11","doi-asserted-by":"publisher","first-page":"353","DOI":"10.2169\/internalmedicine.48.1644","volume":"48","author":"H Bando","year":"2009","unstructured":"Bando H, Hashimoto N, Hirota Y, Sakaguchi K, Hisa I, Inoue Y, Imanishi Y, Seino S, Kaji H. Severe hypophosphatemic osteomalacia with Fanconi syndrome, renal tubular acidosis, vitamin D deficiency and primary biliary cirrhosis. Intern Med. 2009;48:353\u20138.","journal-title":"Intern Med"},{"key":"376_CR12","first-page":"719","volume":"53","author":"M Hara","year":"2011","unstructured":"Hara M, Miyazawa R, Takagi A, Kado H, Maki K, Sawada K, You K, Hatta T. Case of fanconi syndrome positive for anti-M2 antibodies revealed by severe hypokalemia and multiple bone fracture. Nihon Jinzo Gakkai Shi. 2011;53:719\u201325.","journal-title":"Nihon Jinzo Gakkai Shi"},{"key":"376_CR13","first-page":"1","volume":"4","author":"T Saeki","year":"2016","unstructured":"Saeki T, Nakajima A, Ito T, Takata T, Imai N, Yoshita K, Kabasawa H, Yamazaki H, Narita I. Tubulointerstitial nephritis and Fanconi syndrome in a patient with primary sj\u00f6gren\u2019s syndrome accompanied by antimitochondrial antibodies: a case report and review of the literature. Mod Rheumatol. 2016;4:1\u20134.","journal-title":"Mod Rheumatol"},{"key":"376_CR14","first-page":"36","volume":"27","author":"IC Macdougall","year":"1987","unstructured":"Macdougall IC, Isles CG, Whitworth JA, More IA, MacSween RN. Interstitial nephritis and primary biliary cirrhosis: a new association? Clin Nephrol. 1987;27:36\u201340.","journal-title":"Clin Nephrol"},{"key":"376_CR15","first-page":"134","volume":"35","author":"M Kamouchi","year":"1991","unstructured":"Kamouchi M, Tsuji H, Hirakata H, Okamura K, Ishitsuka T, Murai K, Onoyama K, Fujishima M. Tubulointerstitial disorders in the kidney associated with primary biliary cirrhosis (PBC). Clin Nephrol. 1991;35:134\u20135.","journal-title":"Clin Nephrol"},{"key":"376_CR16","first-page":"467","volume":"26","author":"B Terrier","year":"2008","unstructured":"Terrier B, Fakhouri F, Berezne A, Bouldouyre MA, Guilpain P, Sogni P, Terris B, No\u00ebl LH, Guillevin L, Mouthon L. Osteomalacia revealing celiac disease and primary biliary cirrhosis-related fanconi syndrome in a patient with systemic sclerosis. Clin Exp Rheumatol. 2008;26:467\u201370.","journal-title":"Clin Exp Rheumatol"},{"key":"376_CR17","doi-asserted-by":"publisher","first-page":"3575","DOI":"10.1093\/ndt\/gfq232","volume":"25","author":"A Komatsuda","year":"2010","unstructured":"Komatsuda A, Wakui H, Ohtani H, Masai R, Okuyama S, Nimura T, Suzuki N, Sawada K. Tubulointerstitial nephritis and renal tubular acidosis of different types are rare but important complications of primary biliary cirrhosis. Nephrol Dial Transpl. 2010;25:3575\u20139.","journal-title":"Nephrol Dial Transpl"},{"key":"376_CR18","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1093\/ckj\/sfs085","volume":"5","author":"T Bansal","year":"2012","unstructured":"Bansal T, Takou A, Khwaja A. Progressive chronic kidney disease secondary to tubulointerstitial nephritis in primary biliary cirrhosis. Clin Kidney J. 2012;5:442\u20134.","journal-title":"Clin Kidney J"},{"key":"376_CR19","doi-asserted-by":"publisher","first-page":"467","DOI":"10.2169\/internalmedicine.52.9003","volume":"52","author":"T Iwakura","year":"2013","unstructured":"Iwakura T, Fujigaki Y, Matsuyama T, Fujikura T, Ohashi N, Yasuda H, Kato A, Baba S. Tubulointerstitial nephritis and primary biliary cirrhosis with a T cell-dominant profile of infiltrating cells and granulomas in both organs. Intern Med. 2013;52:467\u201371.","journal-title":"Intern Med"},{"key":"376_CR20","first-page":"29","volume":"3","author":"M-H Rasolzadegan","year":"2014","unstructured":"Rasolzadegan M-H, Bakhshayesh H, Amid N. Tubulointerstitial nephritis associated with primary biliary cirrhosis. J Nephropharmacol. 2014;3:29\u201331.","journal-title":"J Nephropharmacol"},{"key":"376_CR21","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1186\/s12882-015-0184-4","volume":"16","author":"S Yamaguchi","year":"2015","unstructured":"Yamaguchi S, Maruyama T, Wakino S, Tokuyama H, Hashiguchi A, Tada S, Homma K, Monkawa T, Thomas J, Miyashita K, Kurihara I, Yoshida T, Konishi K, Hayashi K, Hayashi M, Itoh H. A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomotic primary biliary cirrhosis. BMC Nephrol. 2015;16:187.","journal-title":"BMC Nephrol"},{"key":"376_CR22","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1006\/jaut.1998.0220","volume":"11","author":"AC Malmborg","year":"1998","unstructured":"Malmborg AC, Shultz DB, Luton F, Mostov KE, Richly E, Leung PS, Benson GD, Ansari AA, Coppel RL, Gershwin ME, Van de Water J. Penetration and co-localization in MDCK cell mitochondria of IgA derived from patients with primary biliary cirrhosis. J Autoimmun. 1998;11:573\u201380.","journal-title":"J Autoimmun"}],"container-title":["CEN Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13730-019-00376-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-019-00376-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-019-00376-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T00:21:45Z","timestamp":1578961305000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13730-019-00376-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,14]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["376"],"URL":"https:\/\/doi.org\/10.1007\/s13730-019-00376-6","relation":{},"ISSN":["2192-4449"],"issn-type":[{"value":"2192-4449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,14]]},"assertion":[{"value":"22 August 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors have declared that no conflict of interest exists.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee at which the studies were conducted (IRB approval number 29\u201394) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}