{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:24:29Z","timestamp":1740165869316,"version":"3.37.3"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T00:00:00Z","timestamp":1613952000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T00:00:00Z","timestamp":1613952000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CEN Case Rep"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s13730-021-00583-0","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T10:02:57Z","timestamp":1613988177000},"page":"435-441","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Selective immunoglobulin M deficiency complicated by systemic lupus erythematosus and antiphospholipid syndrome: a case report and review of literature"],"prefix":"10.1007","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0278-6900","authenticated-orcid":false,"given":"Yoshinosuke","family":"Shimamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuto","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koki","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yayoi","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Takizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,22]]},"reference":[{"key":"583_CR1","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.3389\/fimmu.2017.01056","volume":"8","author":"S Gupta","year":"2017","unstructured":"Gupta S, Gupta A. Selective IgM deficiency-an underestimated primary immunodeficiency. Front Immunol. 2017;8:1056.","journal-title":"Front Immunol"},{"key":"583_CR2","first-page":"55","volume":"8","author":"DL Lucuab-Fegurgur","year":"2019","unstructured":"Lucuab-Fegurgur DL, Gupta S. Comprehensive clinical and immunological features of 62 adult patients with selective primary IgM deficiency. Am J Clin Exp Immunol. 2019;8:55\u201367.","journal-title":"Am J Clin Exp Immunol"},{"key":"583_CR3","doi-asserted-by":"publisher","first-page":"e23289","DOI":"10.1002\/jcla.23289","volume":"34","author":"J Ni","year":"2020","unstructured":"Ni J, Zhang J, Chen Q, Chen Y, Liu J. The epidemiology and clinical features of selective immunoglobulin M deficiency: a single-center study in China. J Clin Lab Anal. 2020;34:e23289.","journal-title":"J Clin Lab Anal"},{"key":"583_CR4","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.humimm.2015.09.051","volume":"77","author":"N Entezari","year":"2016","unstructured":"Entezari N, Adab Z, Zeydi M, Saghafi S, Jamali M, Kardar GA, et al. The prevalence of selective immunoglobulin M deficiency (SIgMD) in Iranian volunteer blood donors. Hum Immunol. 2016;77:7\u201311.","journal-title":"Hum Immunol"},{"key":"583_CR5","first-page":"884","volume":"78","author":"J Ogura","year":"1989","unstructured":"Ogura J, Yoshio S, Masuyama J, Kumatani M, Karino S. A case of systemic lupus erythematosus associated with systemic IgM deficiency. Nihon Naikagakkai Zasshi. 1989;78:884\u20136 (in Japanese).","journal-title":"Nihon Naikagakkai Zasshi"},{"key":"583_CR6","first-page":"249","volume":"47","author":"T Sasaki","year":"1993","unstructured":"Sasaki T, Denpo K, Takahashi K, Nakajima H, Kameda H. Systemic lupus erythematosus associated with selective IgM deficiency. Rhinsho Hihuka. 1993;47:249\u201352 (in Japanese).","journal-title":"Rhinsho Hihuka"},{"key":"583_CR7","doi-asserted-by":"publisher","first-page":"185","DOI":"10.2329\/perio.38.Supplement1_185","volume":"38","author":"A Tanaka","year":"1996","unstructured":"Tanaka A, Kasahara M, Miyawaki T, Yahata K, Hashimoto H, Sugawara A, et al. A case of selective IgM deficiency associated with systemic lupus erythematosus. Nihon Jinzo Gakkai Shi. 1996;38:185\u201390.","journal-title":"Nihon Jinzo Gakkai Shi"},{"key":"583_CR8","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3109\/08916930109001959","volume":"34","author":"T Takeuchi","year":"2001","unstructured":"Takeuchi T, Nakagawa T, Maeda Y, Hirano S, Sasaki-Hayashi M, Makino S, et al. Functional defect of B lymphocytes in a patient with selective IgM deficiency associated with systemic lupus erythematosus. Autoimmunity. 2001;34:115\u201322.","journal-title":"Autoimmunity"},{"key":"583_CR9","first-page":"212","volume":"27","author":"T Miura","year":"2015","unstructured":"Miura T, Honma R, Iida T, Yamagishi Y. A case of systemic lupus erythematosus associated with selective IgM deficiency. Clin Rheumatol Related Res. 2015;27:212\u20138 (in Japanese).","journal-title":"Clin Rheumatol Related Res"},{"key":"583_CR10","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1111\/j.1523-1755.2004.00443.x","volume":"65","author":"JJ Weening","year":"2004","unstructured":"Weening JJ, D\u2019Agati VD, Schwartz MM, Seshan SV, Alpers CE, Appel GB, et al. The classification of glomerulonephritis in systemic lupus erythematosus revisited. Kidney Int. 2004;65:521\u201330.","journal-title":"Kidney Int"},{"key":"583_CR11","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1111\/j.1538-7836.2006.01753.x","volume":"4","author":"S Miyakis","year":"2006","unstructured":"Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006;4:295\u2013306.","journal-title":"J Thromb Haemost"},{"key":"583_CR12","doi-asserted-by":"publisher","first-page":"866","DOI":"10.2169\/internalmedicine.31.866","volume":"31","author":"T Yamasaki","year":"1992","unstructured":"Yamasaki T. Selective IgM deficiency: functional assessment of peripheral blood lymphocytes in vitro. Intern Med. 1992;31:866\u201370.","journal-title":"Intern Med"},{"key":"583_CR13","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.clim.2015.08.017","volume":"161","author":"A Mensen","year":"2015","unstructured":"Mensen A, Karuse T, Hanitsch LG, Meisel C, Kleint ME, Volk HD, et al. Altered B-cell subsets and functional B-cell defects in selective IgM deficiency. Clin Immunol. 2015;161:96\u2013102.","journal-title":"Clin Immunol"},{"key":"583_CR14","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1007\/BF00918745","volume":"6","author":"T Inoue","year":"1986","unstructured":"Inoue T, Okumura Y, Shirama M, Ishibashi H, Kashiwagi S, Okubo H. Selective partial IgM deficiency: functional assessment of T and B lymphocytes in vitro. J Clin Immunol. 1986;6:130\u20135.","journal-title":"J Clin Immunol"},{"key":"583_CR15","first-page":"630","volume":"68","author":"T Ohno","year":"1987","unstructured":"Ohno T, Inaba M, Kuribayashi K, Masuda T, Kanoh T, Uchino H. Selective IgM deficiency in adults: phenotypically and functionally altered profiles of peripheral blood lymphocytes. Clin Exp Immunol. 1987;68:630\u20137.","journal-title":"Clin Exp Immunol"},{"key":"583_CR16","first-page":"670","volume":"49","author":"EG De la Concha","year":"1982","unstructured":"De la Concha EG, Garcia-Rodriguez MC, Zabay JM, Laso MT, Alonso F, Bootello A, et al. Functional assessment of T and B lymphocytes in patients with selective IgM deficiency. Clin Exp Immunol. 1982;49:670\u20136.","journal-title":"Clin Exp Immunol"},{"key":"583_CR17","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/S1081-1206(10)60962-3","volume":"97","author":"MF Goldstein","year":"2006","unstructured":"Goldstein MF, Goldstein AL, Dunsky EH, Dvorin DJ, Belecanech GA, Shamir K. Selective IgM immunodeficiency: retrospective analysis of 36 adult patients with review of the literature. Ann Allergy Asthma Immunol. 2006;97:717\u201330.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"583_CR18","doi-asserted-by":"publisher","first-page":"4004","DOI":"10.1182\/blood.V90.10.4004","volume":"90","author":"V Hurez","year":"1997","unstructured":"Hurez V, Kazatchkine MD, Vassilev T, Ramanathan S, Pashov A, Basuyaux B, et al. Pooled normal human polyspecific IgM contains neutralizing anti-idiotypes to IgG autoantibodies of autoimmune patients and protects from experimental autoimmune disease. Blood. 1997;90:4004\u201313.","journal-title":"Blood"},{"key":"583_CR19","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.4049\/jimmunol.1401880","volume":"194","author":"TT Nguyen","year":"2015","unstructured":"Nguyen TT, Elsner RA, Baumgarth N. Natural IgM prevents autoimmunity by enforcing B cell central tolerance induction. J Immunol. 2015;194:1489\u2013502.","journal-title":"J Immunol"},{"key":"583_CR20","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1084\/jem.191.7.1253","volume":"191","author":"MR Ehrenstein","year":"2000","unstructured":"Ehrenstein MR, Cook HT, Neuberger MS. Deficiency in serum immunoglobulin (Ig) M predisposes to development of IgG autoantibodies. J Exp Med. 2000;191:1253\u20138.","journal-title":"J Exp Med"},{"key":"583_CR21","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1073\/pnas.97.3.1184","volume":"97","author":"M Boes","year":"2000","unstructured":"Boes M, Schmidt T, Linkemann K, Beaudette BC, Marshak-Rothstein A, Chen J. Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM. Proc Natl Acad Sci USA. 2000;97:1184\u20139.","journal-title":"Proc Natl Acad Sci USA"},{"key":"583_CR22","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1159\/000222682","volume":"150","author":"L Yel","year":"2009","unstructured":"Yel L, Ramanuja S, Gupta S. Clinical and immunological features in IgM deficiency. Int Arch Allergy Immunol. 2009;150:291\u20138.","journal-title":"Int Arch Allergy Immunol"},{"key":"583_CR23","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1084\/jem.192.2.271","volume":"192","author":"N Baumgarth","year":"2000","unstructured":"Baumgarth N, Herman OC, Jager GC, Brown LE, Herzenberg LA, Chen J. B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection. J Exp Med. 2000;192:271\u201380.","journal-title":"J Exp Med"},{"key":"583_CR24","doi-asserted-by":"publisher","first-page":"5755","DOI":"10.4049\/jimmunol.0901638","volume":"184","author":"KS Subramaniam","year":"2010","unstructured":"Subramaniam KS, Datta K, Quintero E, Manix C, Marks MS, Pirofski LA. The absence of serum IgM enhances the susceptibility of mice to pulmonary challenge with Cryptococcus neoformans. J Immunol. 2010;184:5755\u201367.","journal-title":"J Immunol"},{"key":"583_CR25","first-page":"547","volume":"62","author":"MF Guill","year":"1989","unstructured":"Guill MF, Brown DA, Ochs HD, Pyun KH, Moffitt JE. IgM deficiency: clinical spectrum and immunologic assessment. Ann Allergy. 1989;62:547\u201352.","journal-title":"Ann Allergy"},{"key":"583_CR26","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.anai.2015.11.017","volume":"116","author":"MF Goldstein","year":"2016","unstructured":"Goldstein MF, Hilditch GJ, Dvorin DJ, Belecanech GA. Immunoglobulin replacement for selective IgM immunodeficiency, bronchiectasis, and asthma. Ann Allergy Asthma Immunol. 2016;116:172\u20133.","journal-title":"Ann Allergy Asthma Immunol"}],"container-title":["CEN Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-021-00583-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13730-021-00583-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-021-00583-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T07:18:01Z","timestamp":1625815081000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13730-021-00583-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,22]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["583"],"URL":"https:\/\/doi.org\/10.1007\/s13730-021-00583-0","relation":{},"ISSN":["2192-4449"],"issn-type":[{"type":"electronic","value":"2192-4449"}],"subject":[],"published":{"date-parts":[[2021,2,22]]},"assertion":[{"value":"30 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 February 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors have declared that no conflict of interest exists.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee at which the studies were conducted (IRB approval number: H19-8908) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}