{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T12:10:55Z","timestamp":1778155855783,"version":"3.51.4"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CEN Case Rep"],"DOI":"10.1007\/s13730-026-01103-8","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:17:35Z","timestamp":1778152655000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Familial hypomagnesemia with hypercalciuria and nephrocalcinosis treated with living-donor kidney transplantation: case report"],"prefix":"10.1007","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9685-9026","authenticated-orcid":false,"given":"Akari","family":"Kaba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keizo","family":"Kaku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kodai","family":"Shingaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Kubo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Hisadome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Nishiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Okabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"key":"1103_CR1","doi-asserted-by":"publisher","DOI":"10.5935\/0101-2800.20140057","author":"JR Almeida","year":"2014","unstructured":"Almeida JR, Machado GA, dos Santos MM, Lopes PF, de Matos JP, Neves AC, et al. Five years results after intrafamilial kidney post-transplant in a case of familial hypomagnesemia due to a claudin-19 mutation. J Bras Nefrol. 2014. https:\/\/doi.org\/10.5935\/0101-2800.20140057.","journal-title":"J Bras Nefrol"},{"key":"1103_CR2","first-page":"209","volume":"16","author":"T Malakoutian","year":"2022","unstructured":"Malakoutian T, Madadi B, Saber S. A novel mutation in CLDN16 gene causing familial hypomagnesemia, hypercalciuria, nephrocalcinosis in an Iranian family. Iran J Kidney Dis. 2022;16:209\u201313.","journal-title":"Iran J Kidney Dis"},{"key":"1103_CR3","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2014.977141","author":"ME Arteaga","year":"2015","unstructured":"Arteaga ME, Hunziker W, Teo ASM, Hillmer AM, Mutchinick OM. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: variable phenotypic expression in three affected sisters from Mexican ancestry. Ren Fail. 2015. https:\/\/doi.org\/10.3109\/0886022X.2014.977141.","journal-title":"Ren Fail"},{"key":"1103_CR4","doi-asserted-by":"publisher","unstructured":"Loris Pablo C, Mart\u00edn de Vicente C, Abio Albero S, Justa Rold\u00e1n M, Ferrer Novella C. Hipomagnesemia familiar con hipercalciuria y nefrocalcinosis y asociaci\u00f3n con alteraciones oculares Familial hypomagnesemia with hypercalciuria and nephrocalcinosis Association with ocular abnormalities. An Pediatr. 2004; https:\/\/doi.org\/10.1016\/s1695-4033(04)78436-2.","DOI":"10.1016\/s1695-4033(04)78436-2"},{"key":"1103_CR5","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-021-04968-2","author":"M Vall-Palomar","year":"2021","unstructured":"Vall-Palomar M, Madariaga L, Ariceta G. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis. Pediatr Nephrol. 2021. https:\/\/doi.org\/10.1007\/s00467-021-04968-2.","journal-title":"Pediatr Nephrol"},{"key":"1103_CR6","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5200475","author":"S Weber","year":"2000","unstructured":"Weber S, Hoffmann K, Jeck N, Saar K, Boeswald M, Kuwertz-Broeking E, et al. Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis maps to chromosome 3q27 and is associated with mutations in the PCLN-1 gene. Eur J Hum Genet. 2000. https:\/\/doi.org\/10.1038\/sj.ejhg.5200475.","journal-title":"Eur J Hum Genet"},{"key":"1103_CR7","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/15.5.605","author":"V Benigno","year":"2000","unstructured":"Benigno V, Canonica CS, Bettinelli A, von Vigier RO, Truttmann AC, Bianchetti MG. Hypomagnesaemia-hypercalciuria-nephrocalcinosis: a report of nine cases and a review. Nephrol Dial Transpl. 2000. https:\/\/doi.org\/10.1093\/ndt\/15.5.605.","journal-title":"Nephrol Dial Transpl"},{"key":"1103_CR8","doi-asserted-by":"publisher","unstructured":"Kari JA, Farouq M, Alshaya HO. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis. Pediatr Nephrol. 2003; https:\/\/doi.org\/10.1007\/s00467-003-1139-8","DOI":"10.1007\/s00467-003-1139-8"},{"key":"1103_CR9","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.12841211","author":"A Godron","year":"2012","unstructured":"Godron A, Harambat J, Boccio V, Mensire A, May A, Rigothier C, et al. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: phenotype\u2013genotype correlation and outcome in 32 patients with CLDN16 or CLDN19 mutations. Clin J Am Soc Nephrol. 2012. https:\/\/doi.org\/10.2215\/CJN.12841211.","journal-title":"Clin J Am Soc Nephrol"},{"key":"1103_CR10","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1995.199","author":"M Praga","year":"1995","unstructured":"Praga M, Vara J, Gonz\u00e1lez-Parra E, Andr\u00e9s A, Alamo C, Araque A, et al. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis. Kidney Int. 1995. https:\/\/doi.org\/10.1038\/ki.1995.199.","journal-title":"Kidney Int"},{"key":"1103_CR11","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007060709","author":"M Konrad","year":"2008","unstructured":"Konrad M, Hou J, Weber S, D\u00f6tsch J, Kari JA, Seeman T, et al. CLDN16 genotype predicts renal decline in familial hypomagnesemia with hypercalciuria and nephrocalcinosis. J Am Soc Nephrol. 2008. https:\/\/doi.org\/10.1681\/ASN.2007060709.","journal-title":"J Am Soc Nephrol"},{"key":"1103_CR12","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.67.171","author":"K Okada","year":"2005","unstructured":"Okada K, Ishikawa N, Fujimori K, Goryo M, Ikeda M, Sasaki J, et al. Abnormal development of nephrons in claudin-16-defective Japanese black cattle. J Vet Med Sci. 2005. https:\/\/doi.org\/10.1292\/jvms.67.171.","journal-title":"J Vet Med Sci"},{"key":"1103_CR13","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-002-0884-4","author":"MT Wolf","year":"2002","unstructured":"Wolf MT, D\u00f6tsch J, Konrad M, B\u00f6swald M, Rascher W. Follow-up of five patients with FHHNC due to mutations in the Paracellin-1 gene. Pediatr Nephrol. 2002. https:\/\/doi.org\/10.1007\/s00467-002-0884-4.","journal-title":"Pediatr Nephrol"},{"key":"1103_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2016.04.004","author":"F Lv","year":"2016","unstructured":"Lv F, Xu X-J, Wang J-Y, Liu Y, Jiang Y, Wang O, et al. A novel mutation in CLDN16 results in rare familial hypomagnesaemia with hypercalciuria and nephrocalcinosis in a Chinese family. Clin Chim Acta. 2016. https:\/\/doi.org\/10.1016\/j.cca.2016.04.004.","journal-title":"Clin Chim Acta"},{"key":"1103_CR15","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-003-1304-0","author":"T Tajima","year":"2003","unstructured":"Tajima T, Nakae J, Fujieda K. Two heterozygous mutations of CLDN16 in a Japanese patient with FHHNC. Pediatr Nephrol. 2003. https:\/\/doi.org\/10.1007\/s00467-003-1304-0.","journal-title":"Pediatr Nephrol"},{"key":"1103_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-9-12","author":"G Hampson","year":"2008","unstructured":"Hampson G, Konrad MA, Scoble J. Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC): compound heterozygous mutation in the claudin 16 (CLDN16) gene. BMC Nephrol. 2008. https:\/\/doi.org\/10.1186\/1471-2369-9-12.","journal-title":"BMC Nephrol"},{"key":"1103_CR17","doi-asserted-by":"publisher","DOI":"10.1007\/BF00858976","author":"JC Nicholson","year":"1995","unstructured":"Nicholson JC, Jones CL, Powell HR, Walker RG, McCredie DA. Familial hypomagnesaemia\u2013hypercalciuria leading to end-stage renal failure. Pediatr Nephrol. 1995. https:\/\/doi.org\/10.1007\/BF00858976.","journal-title":"Pediatr Nephrol"}],"container-title":["CEN Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-026-01103-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13730-026-01103-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-026-01103-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:17:36Z","timestamp":1778152656000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13730-026-01103-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,7]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["1103"],"URL":"https:\/\/doi.org\/10.1007\/s13730-026-01103-8","relation":{},"ISSN":["2192-4449"],"issn-type":[{"value":"2192-4449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,7]]},"assertion":[{"value":"4 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have declared that no competing interests exists.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"Written informed consent was obtained from the patient included in this case study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}],"article-number":"84"}}