{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:05:09Z","timestamp":1777633509760,"version":"3.51.4"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CEN Case Rep"],"DOI":"10.1007\/s13730-026-01125-2","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:41:13Z","timestamp":1777437673000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Carbon dioxide contrast angiography-and computed tomography-guided percutaneous embolization of the renal allograft artery in a patient with graft intolerance syndrome and iodinated contrast allergy: a case report"],"prefix":"10.1007","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5705-7612","authenticated-orcid":false,"given":"Takahiro","family":"Shinzato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Imaizumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeo","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kojiro","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaowei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cong","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Okawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenta","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Matsuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Mori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"1125_CR1","doi-asserted-by":"publisher","first-page":"11147","DOI":"10.3389\/ti.2023.11147","volume":"36","author":"K Bunthof","year":"2023","unstructured":"Bunthof K, Saboerali K, Wetering JV, et al. Can we predict graft intolerance syndrome after kidney transplant failure? External validation of a previously developed model. Transpl Int. 2023;36:11147.","journal-title":"Transpl Int"},{"key":"1125_CR2","first-page":"220","volume":"31","author":"KL Bunthof","year":"2018","unstructured":"Bunthof KL, Verhoeks CM, van den Brand JA, et al. Graft intolerance syndrome requiring graft nephrectomy after late kidney graft failure: can it be predicted? A retrospective cohort study Transpl Int. 2018;31:220\u20139.","journal-title":"A retrospective cohort study Transpl Int"},{"key":"1125_CR3","doi-asserted-by":"publisher","first-page":"3","DOI":"10.25259\/JCIS_109_2022","volume":"13","author":"H Hindi","year":"2023","unstructured":"Hindi H, Harb A. Role of failed renal allograft embolization in the treatment of graft intolerance syndrome. J Clin Imaging Sci. 2023;13:3.","journal-title":"J Clin Imaging Sci"},{"key":"1125_CR4","doi-asserted-by":"publisher","first-page":"2937","DOI":"10.1111\/ajt.16717","volume":"21","author":"M Lubetzky","year":"2021","unstructured":"Lubetzky M, Tantisattamo E, Molnar MZ, et al. The failing kidney allograft: a review and recommendations for the care and management of a complex group of patients. Am J Transplant. 2021;21:2937\u201349.","journal-title":"Am J Transplant"},{"key":"1125_CR5","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1111\/j.1399-3062.2009.00467.x","volume":"12","author":"MT P\u00e9rez Rodr\u00edguez","year":"2010","unstructured":"P\u00e9rez Rodr\u00edguez MT, Sope\u00f1a B, Lueiro F, et al. Late infection of an embolized renal graft presented as buttock cellulitis. Transpl Infect Dis. 2010;12:161\u20133.","journal-title":"Transpl Infect Dis"},{"key":"1125_CR6","doi-asserted-by":"publisher","first-page":"4036","DOI":"10.1093\/ndt\/gfn362","volume":"23","author":"I Krause","year":"2008","unstructured":"Krause I, Cleper R, Belenky A, et al. Graft intolerance syndrome in children with failed kidney allografts\u2014clinical presentation, treatment options and outcome. Nephrol Dial Transplant. 2008;23:4036\u201340.","journal-title":"Nephrol Dial Transplant"},{"key":"1125_CR7","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.transproceed.2024.11.027","volume":"57","author":"MP Collado","year":"2025","unstructured":"Collado MP, Ure\u00f1a PG, Mart\u00ednez EG, et al. Graft intolerance syndrome complicates retransplantation. Transplant Proc. 2025;57:30\u20132.","journal-title":"Transplant Proc"},{"key":"1125_CR8","doi-asserted-by":"publisher","first-page":"2953","DOI":"10.1016\/j.transproceed.2013.08.054","volume":"45","author":"IO Sun","year":"2013","unstructured":"Sun IO, Hong YA, Park HS, et al. Comparison of the clinical characteristics of renal transplant recipients who underwent early versus late graft nephrectomy. Transplant Proc. 2013;45:2953\u20136.","journal-title":"Transplant Proc"},{"key":"1125_CR9","volume":"29","author":"U Pession","year":"2023","unstructured":"Pession U, Lammers I, Hauser I, et al. Transplant nephrectomy: a comparative study of timing and techniques in a single institution. Ann Transplant. 2023;29:942252.","journal-title":"Ann Transplant"},{"key":"1125_CR10","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1007\/s11255-018-1960-4","volume":"50","author":"Y Chowaniec","year":"2018","unstructured":"Chowaniec Y, Luyckx F, Karam G, et al. Transplant nephrectomy after graft failure: is it so risky? Impact on morbidity, mortality and alloimmunization. Int Urol Nephrol. 2018;50:1787\u201393.","journal-title":"Int Urol Nephrol"},{"key":"1125_CR11","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/S0272-6386(12)80934-6","volume":"22","author":"V Lorenzo","year":"1993","unstructured":"Lorenzo V, D\u00edaz F, Perez L, et al. Ablation of irreversibly rejected renal allograft by embolization with absolute ethanol: a new clinical application. Am J Kidney Dis. 1993;22:592\u20135.","journal-title":"Am J Kidney Dis"},{"key":"1125_CR12","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1053\/j.ajkd.2005.04.024","volume":"46","author":"P Delgado","year":"2005","unstructured":"Delgado P, Diaz F, Gonzalez A, et al. Intolerance syndrome in failed renal allografts: incidence and efficacy of percutaneous embolization. Am J Kidney Dis. 2005;46:339\u201344.","journal-title":"Am J Kidney Dis"},{"key":"1125_CR13","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s00270-002-1976-z","volume":"26","author":"E Atar","year":"2003","unstructured":"Atar E, Belenky A, Neuman-Levin M, et al. Nonfunctioning renal allograft embolization as an alternative to graft nephrectomy: report on seven years\u2019 experience. Cardiovasc Intervent Radiol. 2003;26:37\u20139.","journal-title":"Cardiovasc Intervent Radiol"},{"key":"1125_CR14","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1046\/j.1464-410x.2000.00881.x","volume":"86","author":"C Gonz\u00e1lez-Satu\u00e9","year":"2000","unstructured":"Gonz\u00e1lez-Satu\u00e9 C, Riera L, Franco E, et al. Percutaneous embolization of the failed renal allograft in patients with graft intolerance syndrome. BJU Int. 2000;86:610\u20132.","journal-title":"BJU Int"},{"key":"1125_CR15","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/j.1432-2277.2002.tb00145.x","volume":"15","author":"F Cofan","year":"2002","unstructured":"Cofan F, Real MI, Vilardell J, et al. Percutaneous renal artery embolisation of non-functioning renal allografts with clinical intolerance. Transpl Int. 2002;15:149\u201355.","journal-title":"Transpl Int"},{"key":"1125_CR16","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1007\/s11547-020-01294-9","volume":"126","author":"M Fantoni","year":"2020","unstructured":"Fantoni M, Marcato C, Ciuni A, et al. Renal artery embolization of non-functioning graft: an effective treatment for graft intolerance syndrome. Radiol Med. 2020;126:494\u20137.","journal-title":"Radiol Med"},{"key":"1125_CR17","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1016\/j.transproceed.2020.01.051","volume":"52","author":"PK Garcia-Padilla","year":"2020","unstructured":"Garcia-Padilla PK, Afanador D, Gonzalez CG, et al. Renal graft embolization as a treatment for graft intolerance syndrome. Transplant Proc. 2020;52:1187\u201391.","journal-title":"Transplant Proc"},{"key":"1125_CR18","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1016\/S0041-1345(03)00576-1","volume":"35","author":"V Lorenzo","year":"2003","unstructured":"Lorenzo V, D\u00edaz F, Perez L, et al. Transvascular ethanol embolization: first option for the management of graft intolerance syndrome. Transplant Proc. 2003;35:1694\u20136.","journal-title":"Transplant Proc"},{"key":"1125_CR19","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1111\/tri.12927","volume":"29","author":"G Al Badaai","year":"2017","unstructured":"Al Badaai G, Pernin V, Garrigue V, et al. Renal graft intolerance syndrome in late graft failure patients: efficacy and safety of embolization as first-line treatment compared to surgical removal. Transpl Int. 2017;29:484\u201393.","journal-title":"Transpl Int"},{"key":"1125_CR20","doi-asserted-by":"publisher","first-page":"207","DOI":"10.12659\/AOT.907700","volume":"23","author":"HM Takase","year":"2018","unstructured":"Takase HM, Contti MM, Nga HS, et al. Nephrectomy versus embolization of non-functioning renal graft: a systematic review with a proportional meta-analysis. Ann Transplant. 2018;23:207\u201317.","journal-title":"Ann Transplant"},{"key":"1125_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00330-025-12001-5","volume":"35","author":"RP Wawer Matos Reimer","year":"2025","unstructured":"Wawer Matos Reimer RP, Reimer P, Mahnken AH, et al. Safety and evidence of CO\u2082 as a vascular contrast agent as an alternative to iodine-based contrast media in vascular procedures: a systematic review by the ESUR contrast medium safety committee. Eur Radiol. 2025;35:1\u20138.","journal-title":"Eur Radiol"},{"key":"1125_CR22","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s003300050400","volume":"8","author":"IF Hawkins","year":"1998","unstructured":"Hawkins IF, Caridi JG. Carbon dioxide (CO\u2082) digital subtraction angiography: 26-year experience at the University of Florida. Eur Radiol. 1998;8:391\u2013402.","journal-title":"Eur Radiol"},{"key":"1125_CR23","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v12.i2.76","volume":"12","author":"A Gupta","year":"2020","unstructured":"Gupta A, Dosekun AK, Kumar V. Carbon dioxide angiography for patients with peripheral arterial disease at risk of contrast-induced nephropathy. World J Cardiol. 2020;12:76.","journal-title":"World J Cardiol"},{"key":"1125_CR24","doi-asserted-by":"publisher","DOI":"10.5758\/vsi.2015.31.3.67","volume":"31","author":"KJ Cho","year":"2015","unstructured":"Cho KJ. Carbon dioxide angiography: scientific principles and practice. Vasc Specialist Int. 2015;31:67.","journal-title":"Vasc Specialist Int"},{"key":"1125_CR25","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.avsg.2019.11.009","volume":"65","author":"BJ Hasjim","year":"2020","unstructured":"Hasjim BJ, Fujitani RM, Chen SL, et al. Utilization of carbon dioxide angiography and percutaneous balloon angioplasty for treatment of transplant renal artery stenosis. Ann Vasc Surg. 2020;65:10\u20136.","journal-title":"Ann Vasc Surg"},{"key":"1125_CR26","first-page":"1424","volume":"28","author":"P Singh","year":"2014","unstructured":"Singh P, Feld RI, Colombe BW, et al. Sensitization, pathologic, and imaging findings comparing symptomatic and quiescent failed renal allografts. Clin Transl Sci. 2014;28:1424\u201332.","journal-title":"Clin Transl Sci"},{"issue":"Suppl 1","key":"1125_CR27","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1159\/000511558","volume":"144","author":"M Tomonari","year":"2020","unstructured":"Tomonari M, Kobayashi A, Yamamoto I, et al. A case of transplant nephrectomy due to chronic graft intolerance syndrome. Nephron. 2020;144(Suppl 1):102\u20137.","journal-title":"Nephron"},{"key":"1125_CR28","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1111\/ajt.16326","volume":"21","author":"CD Mejia","year":"2020","unstructured":"Mejia CD, Frank AM, Singh P, et al. Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient. Am J Transplant. 2020;21:1322\u20135.","journal-title":"Am J Transplant"},{"key":"1125_CR29","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1177\/1078155220934160","volume":"27","author":"SA Padala","year":"2021","unstructured":"Padala SA, Patel SK, Vakiti A, et al. Pembrolizumab-induced severe rejection and graft intolerance syndrome resulting in renal allograft nephrectomy. J Oncol Pharm Pract. 2021;27:470\u20136.","journal-title":"J Oncol Pharm Pract"}],"container-title":["CEN Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-026-01125-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13730-026-01125-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13730-026-01125-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:41:32Z","timestamp":1777437692000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13730-026-01125-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,29]]},"references-count":29,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["1125"],"URL":"https:\/\/doi.org\/10.1007\/s13730-026-01125-2","relation":{},"ISSN":["2192-4449"],"issn-type":[{"value":"2192-4449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,29]]},"assertion":[{"value":"20 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have declared that no Conflict of interest exists.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was reviewed by the institutional review board, and ethical approval was confirmed; however, an IRB approval number was not issued for this type of single case report. The study was conducted in accordance with the 1964 Helsinki declaration and its later amendments. The studies were in accordance with the Declaration of Istanbul.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}],"article-number":"83"}}