{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T11:43:11Z","timestamp":1793878991613,"version":"4.7.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurol Belg"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1007\/s13760-020-01451-x","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T10:05:22Z","timestamp":1596449122000},"page":"1641-1647","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Analysis of cerebellum with magnetic resonance 3D T1 sequence in individuals with chronic subjective tinnitus"],"prefix":"10.1007","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9782-7378","authenticated-orcid":false,"given":"C.","family":"Sahin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1719-4190","authenticated-orcid":false,"given":"S.","family":"Avnioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3429-8610","authenticated-orcid":false,"given":"O.","family":"Ozen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5138-5583","authenticated-orcid":false,"given":"B.","family":"Candan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,3]]},"reference":[{"key":"1451_CR1","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.heares.2015.08.014","volume":"333","author":"T Pattyn","year":"2016","unstructured":"Pattyn T, Van Den Eede F, Vanneste S, Cassiers L, Veltman DJ, Van De Heyning P, Sabbe BCG (2016) Tinnitus and anxiety disorders: A review. Hear Res 333:255\u2013265. https:\/\/doi.org\/10.1016\/j.heares.2015.08.014","journal-title":"Hear Res"},{"key":"1451_CR2","doi-asserted-by":"publisher","first-page":"221","DOI":"10.3389\/fnagi.2016.00221","volume":"8","author":"TW Allan","year":"2016","unstructured":"Allan TW, Besle J, Langers DR, Davies J, Hall DA, Palmer AR, Adjamian P (2016) Neuroanatomical alterations in tinnitus assessed with magnetic resonance imaging. Front Aging Neurosci 8:221. https:\/\/doi.org\/10.3389\/fnagi.2016.00221","journal-title":"Front Aging Neurosci"},{"key":"1451_CR3","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.brainres.2017.11.012","volume":"1679","author":"SA Schmidt","year":"2018","unstructured":"Schmidt SA, Zimmerman B, Bido Medina RO, Carpenter-Thompson JR, Husain FT (2018) Changes in gray and white matter in subgroups within the tinnitus population. Brain Res 1679:64\u201374. https:\/\/doi.org\/10.1016\/j.brainres.2017.11.012","journal-title":"Brain Res"},{"issue":"9","key":"1451_CR4","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1093\/cercor\/bhj070","volume":"16","author":"M Muhlau","year":"2006","unstructured":"Muhlau M, Rauschecker JP, Oestreicher E, Gaser C, Rottinger M, Wohlschlager AM, Simon F, Etgen T, Conrad B, Sander D (2006) Structural brain changes in tinnitus. Cerebral Cortex 16(9):1283\u20131288. https:\/\/doi.org\/10.1093\/cercor\/bhj070","journal-title":"Cerebral Cortex"},{"key":"1451_CR5","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3389\/fnsys.2012.00021","volume":"6","author":"AM Leaver","year":"2012","unstructured":"Leaver AM, Seydell-Greenwald A, Turesky TK, Morgan S, Kim HJ, Rauschecker JP (2012) Cortico-limbic morphology separates tinnitus from tinnitus distress. Front Syst Neurosci 6:21. https:\/\/doi.org\/10.3389\/fnsys.2012.00021","journal-title":"Front Syst Neurosci"},{"issue":"3","key":"1451_CR6","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.neuroimage.2008.12.045","volume":"45","author":"P Schneider","year":"2009","unstructured":"Schneider P, Andermann M, Wengenroth M, Goebel R, Flor H, Rupp A, Diesch E (2009) Reduced volume of Heschl's gyrus in tinnitus. NeuroImage 45(3):927\u2013939. https:\/\/doi.org\/10.1016\/j.neuroimage.2008.12.045","journal-title":"NeuroImage"},{"key":"1451_CR7","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.brainres.2010.10.095","volume":"1369","author":"FT Husain","year":"2011","unstructured":"Husain FT, Medina RE, Davis CW, Szymko-Bennett Y, Simonyan K, Pajor NM, Horwitz B (2011) Neuroanatomical changes due to hearing loss and chronic tinnitus: a combined VBM and DTI study. Brain Res 1369:74\u201388. https:\/\/doi.org\/10.1016\/j.brainres.2010.10.095","journal-title":"Brain Res"},{"key":"1451_CR8","doi-asserted-by":"publisher","first-page":"251308","DOI":"10.1155\/2013\/251308","volume":"2013","author":"M Fabri","year":"2013","unstructured":"Fabri M, Polonara G (2013) Functional topography of human corpus callosum: an FMRI mapping study. Neural Plasticity 2013:251308. https:\/\/doi.org\/10.1155\/2013\/251308","journal-title":"Neural Plasticity"},{"key":"1451_CR9","doi-asserted-by":"publisher","first-page":"4756471","DOI":"10.1155\/2018\/4756471","volume":"2018","author":"Y Liu","year":"2018","unstructured":"Liu Y, Lv H, Zhao P, Liu Z, Chen W, Gong S, Wang Z, Zhu JM (2018) Neuroanatomical alterations in patients with early stage of unilateral pulsatile tinnitus: a voxel-based morphometry study. Neural Plasticity 2018:4756471. https:\/\/doi.org\/10.1155\/2018\/4756471","journal-title":"Neural Plasticity"},{"key":"1451_CR10","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.heares.2018.01.009","volume":"361","author":"LM Mennink","year":"2018","unstructured":"Mennink LM, Van Dijk JMC, Van Der Laan B, Metzemaekers JDM, Van Laar PJ, Van Dijk P (2018) The relation between flocculus volume and tinnitus after cerebellopontine angle tumor surgery. Hear Res 361:113\u2013120. https:\/\/doi.org\/10.1016\/j.heares.2018.01.009","journal-title":"Hear Res"},{"key":"1451_CR11","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3389\/fnhum.2017.00022","volume":"11","author":"YC Chen","year":"2017","unstructured":"Chen YC, Wang F, Wang J, Bo F, Xia W, Gu JP, Yin X (2017) Resting-state brain abnormalities in chronic subjective tinnitus: a meta-analysis. Front Human Neurosci 11:22. https:\/\/doi.org\/10.3389\/fnhum.2017.00022","journal-title":"Front Human Neurosci"},{"key":"1451_CR12","doi-asserted-by":"publisher","first-page":"174","DOI":"10.3389\/fnagi.2016.00174","volume":"8","author":"YC Chen","year":"2016","unstructured":"Chen YC, Feng Y, Xu JJ, Mao CN, Xia W, Ren J, Yin X (2016) Disrupted brain functional network architecture in chronic tinnitus patients. Front Aging Neurosci 8:174. https:\/\/doi.org\/10.3389\/fnagi.2016.00174","journal-title":"Front Aging Neurosci"},{"issue":"2","key":"1451_CR13","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.nic.2015.12.008","volume":"26","author":"P Raghavan","year":"2016","unstructured":"Raghavan P, Steven A, Rath T, Gandhi D (2016) Advanced neuroimaging of tinnitus. Neuroimaging Clin N Am 26(2):301\u2013312. https:\/\/doi.org\/10.1016\/j.nic.2015.12.008","journal-title":"Neuroimaging Clin N Am"},{"key":"1451_CR14","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1016\/j.neuroimage.2016.11.003","volume":"147","author":"JE Romero","year":"2017","unstructured":"Romero JE, Coupe P, Giraud R, Ta VT, Fonov V, Park MTM, Chakravarty MM, Voineskos AN, Manjon JV (2017) CERES: A new cerebellum lobule segmentation method. NeuroImage 147:916\u2013924. https:\/\/doi.org\/10.1016\/j.neuroimage.2016.11.003","journal-title":"NeuroImage"},{"key":"1451_CR15","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/j.neuroimage.2012.08.075","volume":"64","author":"JA Bogovic","year":"2013","unstructured":"Bogovic JA, Jedynak B, Rigg R, Du A, Landman BA, Prince JL, Ying SH (2013) Approaching expert results using a hierarchical cerebellum parcellation protocol for multiple inexpert human raters. NeuroImage 64:616\u2013629. https:\/\/doi.org\/10.1016\/j.neuroimage.2012.08.075","journal-title":"NeuroImage"},{"issue":"20","key":"1451_CR16","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1212\/wnl.0000000000004640","volume":"89","author":"IH Palm-Meinders","year":"2017","unstructured":"Palm-Meinders IH, Arkink EB, Koppen H, Amlal S, Terwindt GM, Launer LJ, van Buchem MA, Ferrari MD, Kruit MC (2017) Volumetric brain changes in migraineurs from the general population. Neurology 89(20):2066\u20132074. https:\/\/doi.org\/10.1212\/wnl.0000000000004640","journal-title":"Neurology"},{"issue":"12","key":"1451_CR17","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1017\/s0033291717000642","volume":"47","author":"R Emsley","year":"2017","unstructured":"Emsley R, Asmal L, du Plessis S, Chiliza B, Phahladira L, Kilian S (2017) Brain volume changes over the first year of treatment in schizophrenia: relationships to antipsychotic treatment. Psychol Med 47(12):2187\u20132196. https:\/\/doi.org\/10.1017\/s0033291717000642","journal-title":"Psychol Med"},{"key":"1451_CR18","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.biopsycho.2017.02.002","volume":"124","author":"MD Albaugh","year":"2017","unstructured":"Albaugh MD, Nguyen TV, Ducharme S, Collins DL, Botteron KN, D'Alberto N, Evans AC, Karama S, Hudziak JJ (2017) Age-related volumetric change of limbic structures and subclinical anxious\/depressed symptomatology in typically developing children and adolescents. Biol Psychol 124:133\u2013140. https:\/\/doi.org\/10.1016\/j.biopsycho.2017.02.002","journal-title":"Biol Psychol"},{"key":"1451_CR19","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.heares.2017.09.002","volume":"355","author":"N Scott-Wittenborn","year":"2017","unstructured":"Scott-Wittenborn N, Karadaghy OA, Piccirillo JF, Peelle JE (2017) A methodological assessment of studies that use voxel-based morphometry to study neural changes in tinnitus patients. Hear Res 355:23\u201332. https:\/\/doi.org\/10.1016\/j.heares.2017.09.002","journal-title":"Hear Res"},{"key":"1451_CR20","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/b978-0-444-63956-1.00006-0","volume":"154","author":"E D'Angelo","year":"2018","unstructured":"D'Angelo E (2018) Physiology of the cerebellum. Handbook Clin Neurol 154:85\u2013108. https:\/\/doi.org\/10.1016\/b978-0-444-63956-1.00006-0","journal-title":"Handbook Clin Neurol"},{"key":"1451_CR21","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/b978-0-444-63956-1.00004-7","volume":"154","author":"CJ Stoodley","year":"2018","unstructured":"Stoodley CJ, Schmahmann JD (2018) Functional topography of the human cerebellum. Handbook Clin Neurol 154:59\u201370. https:\/\/doi.org\/10.1016\/b978-0-444-63956-1.00004-7","journal-title":"Handbook Clin Neurol"},{"key":"1451_CR22","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.heares.2012.02.010","volume":"295","author":"K Boyen","year":"2013","unstructured":"Boyen K, Langers DR, de Kleine E, van Dijk P (2013) Gray matter in the brain: differences associated with tinnitus and hearing loss. Hear Res 295:67\u201378. https:\/\/doi.org\/10.1016\/j.heares.2012.02.010","journal-title":"Hear Res"},{"key":"1451_CR23","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3389\/fnagi.2017.00031","volume":"9","author":"JE Davies","year":"2017","unstructured":"Davies JE, Gander PE, Hall DA (2017) Does chronic tinnitus alter the emotional response function of the amygdala?: a sound-evoked fMRI study. Fron Aging Neurosci 9:31. https:\/\/doi.org\/10.3389\/fnagi.2017.00031","journal-title":"Fron Aging Neurosci"},{"issue":"11","key":"1451_CR24","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1016\/j.ejrad.2016.09.011","volume":"85","author":"H Lv","year":"2016","unstructured":"Lv H, Zhao P, Liu Z, Li R, Zhang L, Wang P, Yan F, Liu L, Wang G, Zeng R, Li T, Dong C, Gong S, Wang Z (2016) Abnormal resting-state functional connectivity study in unilateral pulsatile tinnitus patients with single etiology: A seed-based functional connectivity study. Eur J Radiol 85(11):2023\u20132029. https:\/\/doi.org\/10.1016\/j.ejrad.2016.09.011","journal-title":"Eur J Radiol"},{"issue":"6","key":"1451_CR25","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1007\/s10548-016-0511-5","volume":"29","author":"HB Yoo","year":"2016","unstructured":"Yoo HB, De Ridder D, Vanneste S (2016) The importance of aging in gray matter changes within tinnitus patients shown in cortical thickness. Surface Area Volume Brain Topography 29(6):885\u2013896. https:\/\/doi.org\/10.1007\/s10548-016-0511-5","journal-title":"Surface Area Volume Brain Topography"},{"issue":"4","key":"1451_CR26","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1007\/s00429-013-0520-z","volume":"218","author":"M Schecklmann","year":"2013","unstructured":"Schecklmann M, Lehner A, Poeppl TB, Kreuzer PM, Rupprecht R, Rackl J, Burger J, Frank E, Hajak G, Langguth B, Landgrebe M (2013) Auditory cortex is implicated in tinnitus distress: a voxel-based morphometry study. Brain Struc Func 218(4):1061\u20131070. https:\/\/doi.org\/10.1007\/s00429-013-0520-z","journal-title":"Brain Struc Func"},{"issue":"6","key":"1451_CR27","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1089\/brain.2014.0255","volume":"5","author":"S Vanneste","year":"2015","unstructured":"Vanneste S, De Ridder D (2015) Stress-related functional connectivity changes between auditory cortex and cingulate in tinnitus. Brain Connect 5(6):371\u2013383. https:\/\/doi.org\/10.1089\/brain.2014.0255","journal-title":"Brain Connect"},{"key":"1451_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2018.00059","author":"Y Feng","year":"2018","unstructured":"Feng Y, Chen Y-C, Lv H, Xia W, Mao C-N, Bo F, Chen H, Xu J-J, Yin X (2018) Increased resting-state cerebellar-cerebral functional connectivity underlying chronic tinnitus. Front Aging Neurosci. https:\/\/doi.org\/10.3389\/fnagi.2018.00059","journal-title":"Front Aging Neurosci"},{"key":"1451_CR29","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.heares.2012.03.009","volume":"295","author":"CA Bauer","year":"2013","unstructured":"Bauer CA, Kurt W, Sybert LT, Brozoski TJ (2013) The cerebellum as a novel tinnitus generator. Hear Res 295:130\u2013139. https:\/\/doi.org\/10.1016\/j.heares.2012.03.009","journal-title":"Hear Res"},{"issue":"6","key":"1451_CR30","doi-asserted-by":"publisher","first-page":"1678","DOI":"10.1007\/s11682-018-9835-y","volume":"12","author":"TN Akudjedu","year":"2018","unstructured":"Akudjedu TN, Nabulsi L, Makelyte M, Scanlon C, Hehir S, Casey H, Ambati S, Kenney J, O'Donoghue S, McDermott E, Kilmartin L, Dockery P, McDonald C, Hallahan B, Cannon DM (2018) A comparative study of segmentation techniques for the quantification of brain subcortical volume. Brain Imag Behav 12(6):1678\u20131695. https:\/\/doi.org\/10.1007\/s11682-018-9835-y","journal-title":"Brain Imag Behav"}],"container-title":["Acta Neurologica Belgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13760-020-01451-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13760-020-01451-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13760-020-01451-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T16:35:20Z","timestamp":1636734920000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13760-020-01451-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1451"],"URL":"https:\/\/doi.org\/10.1007\/s13760-020-01451-x","relation":{},"ISSN":["0300-9009","2240-2993"],"issn-type":[{"value":"0300-9009","type":"print"},{"value":"2240-2993","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,3]]},"assertion":[{"value":"23 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standard"}},{"value":"The authors have no conflict of interest to declare regarding the materials or methods used in this study or the findings presented in this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all involved participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}