{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T18:13:58Z","timestamp":1764180838326,"version":"3.46.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T00:00:00Z","timestamp":1749168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T00:00:00Z","timestamp":1749168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurol Belg"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s13760-025-02818-8","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T05:56:44Z","timestamp":1749189404000},"page":"1521-1524","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hung-up reflex: the history of a clinical sign and differential diagnosis"],"prefix":"10.1007","volume":"125","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8836-8072","authenticated-orcid":false,"given":"Cynthia Patricia","family":"Corona-V\u00e1zquez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1532-929X","authenticated-orcid":false,"given":"Patricia","family":"Orozco-Puga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8645-6132","authenticated-orcid":false,"given":"Fatima Gabriela","family":"Macias-Ortiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0206-322X","authenticated-orcid":false,"given":"Enrique","family":"Gomez--Figueroa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8162-4622","authenticated-orcid":false,"given":"Daniela Isabel","family":"Ochoa-Walker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0110-4878","authenticated-orcid":false,"given":"Omar","family":"Cardenas-Saenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,6]]},"reference":[{"key":"2818_CR7","doi-asserted-by":"publisher","first-page":"e255008","DOI":"10.1136\/bcr-2023-255008","volume":"16","author":"T Chen","year":"2023","unstructured":"Chen T (2023) Hung-up knee jerk in stiff-person syndrome. BMJ Case Rep 16:e255008\u2013e255008","journal-title":"BMJ Case Rep"},{"key":"2818_CR8","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1212\/WNL.0000000000200938","volume":"99","author":"A L\u00f3pez-Jim\u00e9nez","year":"2022","unstructured":"L\u00f3pez-Jim\u00e9nez A, Guti\u00e9rrez-Guti\u00e9rrez G, Guerra-Hiraldo JD, Kurtis MM, Pare\u00e9s I (2022) Teaching video neuroimage: hung-up reflex in stiff limb syndrome. Neurology 99:356\u2013356","journal-title":"Neurology"},{"key":"2818_CR9","doi-asserted-by":"publisher","first-page":"e10","DOI":"10.1056\/NEJMicm1910309","volume":"382","author":"T Fukumoto","year":"2020","unstructured":"Fukumoto T, Miyamoto R (2020) Hung-up knee jerk in Huntington\u2019s disease. N Engl J Med 382:e10","journal-title":"N Engl J Med"},{"key":"2818_CR1","first-page":"108","volume":"78","author":"CS Houston","year":"1958","unstructured":"Houston CS (1958) The diagnostic importance of the myxoedema reflex (Woltman\u2019s sign). Can Med Assoc J 78:108\u2013112","journal-title":"Can Med Assoc J"},{"key":"2818_CR3","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1001\/jama.1924.02650510013005","volume":"82","author":"WC Chaney","year":"1924","unstructured":"Chaney WC (1924) Tendon reflexes in myxedema: a valuable aid in diagnosis. JAMA 82:2013\u20132016","journal-title":"JAMA"},{"key":"2818_CR5","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/j.jocn.2012.09.047","volume":"20","author":"DB Burkholder","year":"2013","unstructured":"Burkholder DB, Klaas JP, Kumar N, Boes CJ (2013) The origin of Woltman\u2019s sign of myxoedema. J Clin Neurosci 20:1204\u20131206","journal-title":"J Clin Neurosci"},{"key":"2818_CR4","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1136\/pgmj.44.507.97","volume":"44","author":"G Nuki","year":"1968","unstructured":"Nuki G, Bayliss RI (1968) The Achilles tendon reflex as an index of thyroid function. Postgrad Med J 44:97\u2013102","journal-title":"Postgrad Med J"},{"key":"2818_CR2","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1097\/00007611-197307000-00004","volume":"66","author":"SP Gupta","year":"1973","unstructured":"Gupta SP, Kumar V, Ahuja MMS (1973) Evaluation of Achilles reflex time as a test of thyroid function. South Med J 66:754\u2013758","journal-title":"South Med J"},{"key":"2818_CR6","doi-asserted-by":"publisher","first-page":"131","DOI":"10.31782\/IJCRR.2021.13138","volume":"13","author":"L Sham","year":"2021","unstructured":"Sham L, Sachin D, Richa C (2021) Hung up reflex, clincher to Hypothyroidism\u2013 A case report. Int J Cur Res Rev 13:131\u2013133","journal-title":"Int J Cur Res Rev"},{"key":"2818_CR10","doi-asserted-by":"crossref","unstructured":"Lau KM, Lau YH (2024) \u2018Hung-up\u2019knee jerk as an initial diagnostic clue of huntington disease. Parkinsonism Relat Disord Vol 122","DOI":"10.1016\/j.parkreldis.2024.106848"},{"key":"2818_CR14","unstructured":"Mu\u00f1uzuri, Rodr\u00edguez (2017) Cervantes. Descripci\u00f3n Del hung up knee jerk reflex En Una Poblaci\u00f3n de Pacientes Mexicanos Con Enfermedad de huntington. Reuni\u00f3n anual de neurolog\u00eda"},{"key":"2818_CR11","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/S1353-8020(02)00095-0","volume":"9","author":"T Brannan","year":"2003","unstructured":"Brannan T (2003) The hung-up knee jerk in Huntington\u2019s disease. Parkinsonism Relat Disord 9:257\u2013259","journal-title":"Parkinsonism Relat Disord"},{"issue":"2","key":"2818_CR18","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1007\/s11940-009-0013-9","volume":"11","author":"MC Dalakas","year":"2009","unstructured":"Dalakas MC (2009) Stiff person syndrome: advances in pathogenesis and therapeutic interventions. Curr Treat Options Neurol 11(2):102\u2013110","journal-title":"Curr Treat Options Neurol"},{"key":"2818_CR15","doi-asserted-by":"publisher","DOI":"10.1186\/1757-1626-3-60","author":"A Hajjioui","year":"2010","unstructured":"Hajjioui A, Benbouazza K, Faris MEA, Missaoui A, Hassouni NH (2010) Stiff limb syndrome: a case report. Cases J [Internet] 3(1):60 Disponible en:. https:\/\/doi.org\/10.1186\/1757-1626-3-60. [citado el 27 de junio de 2024]"},{"issue":"8","key":"2818_CR16","first-page":"356","volume":"99","author":"A L\u00f3pez-Jim\u00e9nez","year":"2022","unstructured":"L\u00f3pez-Jim\u00e9nez A, Guti\u00e9rrez-Guti\u00e9rrez G, Guerra-Hiraldo JD, Kurtis MM, Pare\u00e9s I (2022) Teaching video neuroimage: Hung-up reflex in stiff limb syndrome. Neurol [Internet] 99(8):356\u2013356","journal-title":"Neurol [Internet]"},{"issue":"1","key":"2818_CR17","first-page":"60","volume":"46","author":"PD Garc\u00eda","year":"2022","unstructured":"Garc\u00eda PD, L\u00f3pez S, Santana A, Toledo L, Sebasti\u00e1n I, Cabrera JC (2022) Corea de Sydenham Unilateral, Una Manifestaci\u00f3n rara de Una enfermedad Poco frecuente. A prop\u00f3sito de Un Caso. Sociedades Canarias de pediatr\u00eda. Enero-abril 46(1):60\u201365","journal-title":"Enero-abril"},{"key":"2818_CR13","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780192619112.001.0001","volume-title":"Marsden\u2019s book of movement disorders","author":"I Donaldson","year":"2012","unstructured":"Donaldson I, David Marsden C, Schneider S, Bhatia K (2012) Marsden\u2019s book of movement disorders. Oxford University Press, Londres, Inglaterra"}],"container-title":["Acta Neurologica Belgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13760-025-02818-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13760-025-02818-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13760-025-02818-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T18:09:45Z","timestamp":1764180585000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13760-025-02818-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["2818"],"URL":"https:\/\/doi.org\/10.1007\/s13760-025-02818-8","relation":{"references":[{"id-type":"doi","id":"10.1186\/1757-1626-3-60","asserted-by":"subject"}]},"ISSN":["0300-9009","2240-2993"],"issn-type":[{"type":"print","value":"0300-9009"},{"type":"electronic","value":"2240-2993"}],"subject":[],"published":{"date-parts":[[2025,6,6]]},"assertion":[{"value":"12 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}