{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T15:32:29Z","timestamp":1793892749815,"version":"4.8.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universidade Cesumar"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurol Belg"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anosmia and ageusia are among the most frequent symptoms of post-COVID-19 syndrome, yet their association with neurological symptoms and cardiorespiratory fitness remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the presence of anosmia and ageusia with neurological symptoms and cardiorespiratory fitness in post-COVID-19 individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study included 201 post-COVID-19 individuals who completed a standardized questionnaire assessing anosmia, ageusia, and neurological symptoms. Cardiorespiratory fitness was assessed using the Bruce treadmill test with direct measurement of peak oxygen uptake (VO\u2082peak). Missing data were handled by multiple imputation. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated using binary logistic regression, adjusted for age, sex, acute infection severity, medical history, body fat percentage, and skeletal muscle mass.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After adjustment, anosmia was independently associated with dizziness (OR\u2009=\u20092.22; 95% CI 1.15\u20134.31) and aural fullness (OR\u2009=\u20094.54; 95% CI 1.16\u201317.80), and ageusia with memory deficit (OR\u2009=\u20092.91; 95% CI 1.47\u20135.75) and aural fullness (OR\u2009=\u20094.08; 95% CI 1.02\u201316.30). No significant associations were found with tinnitus or hearing loss. VO\u2082peak did not differ significantly between participants with and without anosmia (mean difference 1.13 mL\/kg\/min; Cohen\u2019s d\u2009=\u20090.14; 95% CI\u2009\u2212\u20090.14 to 0.42;\n                      <jats:italic>p\u2009=<\/jats:italic>\n                      \u20090.325) or ageusia (mean difference 1.36 mL\/kg\/min; Cohen\u2019s d\u2009=\u20090.17; 95% CI\u2009\u2212\u20090.12 to 0.45;\n                      <jats:italic>p\u2009=<\/jats:italic>\n                      \u20090.244).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Anosmia and ageusia are associated with neurological symptoms but not with cardiorespiratory fitness in post-COVID-19 individuals, suggesting partially independent phenotypes. These symptoms should be considered in therapeutic assessment and management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s13760-026-03189-4","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T05:28:50Z","timestamp":1789104530000},"page":"2097-2104","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparisons between anosmia and ageusia with neurological symptoms and cardiorespiratory fitness among post-COVID-19 individuals: a cross-sectional study"],"prefix":"10.1007","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9026-0468","authenticated-orcid":false,"given":"Luciana Lozza","family":"de Moraes Marchiori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2987-1665","authenticated-orcid":false,"given":"Gl\u00f3ria","family":"de Moraes Marchiori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0223-8384","authenticated-orcid":false,"given":"Fabiano Mendes","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-6628","authenticated-orcid":false,"given":"Victor Augusto Santos","family":"Perli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3491-3073","authenticated-orcid":false,"given":"Maur\u00edcio Medeiros","family":"Lemos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4625-9128","authenticated-orcid":false,"given":"Braulio Henrique Magnani","family":"Branco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"issue":"2","key":"3189_CR1","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1097\/01.mlg.0000249922.37381.1e","volume":"117","author":"M Suzuki","year":"2007","unstructured":"Suzuki M, Saito K, Min WP, Vladau C, Toida K, Itoh H (2007) Identification of viruses in patients with postviral olfactory dysfunction. 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