{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:58:09Z","timestamp":1789167489509,"version":"build-2803163510"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T00:00:00Z","timestamp":1710201600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T00:00:00Z","timestamp":1710201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31600791"],"award-info":[{"award-number":["31600791"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Scientific and Technological Research Project of Science and Technology Department of Henan Province","award":["222102310185"],"award-info":[{"award-number":["222102310185"]}]},{"name":"Scientific and Technological Research Project of Science and Technology Department of Henan Province","award":["232102311096"],"award-info":[{"award-number":["232102311096"]}]},{"name":"Open Project Program of the Third Affiliated Hospital of Xinxiang Medical University","award":["KFKTYB202117"],"award-info":[{"award-number":["KFKTYB202117"]}]},{"name":"Open Project Program of the Third Affiliated Hospital of Xinxiang Medical University","award":["KFKTZD202102"],"award-info":[{"award-number":["KFKTZD202102"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Tissue Eng Regen Med"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1007\/s13770-024-00629-1","type":"journal-article","created":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T23:02:35Z","timestamp":1710284555000},"page":"571-586","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Exosomes Derived from Mouse Breast Carcinoma Cells Facilitate Diabetic Wound Healing"],"prefix":"10.1007","volume":"21","author":[{"given":"Chao","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenchi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linxiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongwei","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongli","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1750-2392","authenticated-orcid":false,"given":"Wenbin","family":"Nan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,12]]},"reference":[{"key":"629_CR1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.12830","volume":"53","author":"X Qiu","year":"2020","unstructured":"Qiu X, Liu J, Zheng C, Su Y, Bao L, Zhu B, et al. Exosomes released from educated mesenchymal stem cells accelerate cutaneous wound healing via promoting angiogenesis. Cell Prolif. 2020;53:e12830.","journal-title":"Cell Prolif"},{"key":"629_CR2","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.7150\/thno.22958","volume":"8","author":"CY Chen","year":"2018","unstructured":"Chen CY, Rao SS, Ren L, Hu XK, Tan YJ, Hu Y, et al. Exosomal DMBT1 from human urine-derived stem cells facilitates diabetic wound repair by promoting angiogenesis. Theranostics. 2018;8:1607\u201323.","journal-title":"Theranostics"},{"key":"629_CR3","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1056\/NEJM199909023411006","volume":"341","author":"AJ Singer","year":"1999","unstructured":"Singer AJ, Clark RA. Cutaneous wound healing. N Eng J Med. 1999;341:738\u201346.","journal-title":"N Eng J Med"},{"key":"629_CR4","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.2147\/DMSO.S199705","volume":"12","author":"D Zhang","year":"2019","unstructured":"Zhang D, Li Z, Wang Z, Zeng F, Xiao W, Yu A. MicroRNA-126: a promising biomarker for angiogenesis of diabetic wounds treated with negative pressure wound therapy. Diabetes Metab Syndr Obes. 2019;12:1685\u201396.","journal-title":"Diabetes Metab Syndr Obes"},{"key":"629_CR5","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3389\/fbioe.2020.00417","volume":"8","author":"W Zhou","year":"2020","unstructured":"Zhou W, Zi L, Cen Y, You C, Tian M. Copper sulfide nanoparticles-incorporated hyaluronic acid injectable hydrogel with enhanced angiogenesis to promote wound healing. Front Bioeng Biotechnol. 2020;8:417.","journal-title":"Front Bioeng Biotechnol"},{"key":"629_CR6","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.apmt.2018.02.004","volume":"11","author":"RX Wu","year":"2018","unstructured":"Wu RX, Xu XY, Wang J, He XT, Sun HH, Chen FM. Biomaterials for endogenous regenerative medicine: coaxing stem cell homing and beyond. Appl Mater Today. 2018;11:144\u201365.","journal-title":"Appl Mater Today"},{"key":"629_CR7","doi-asserted-by":"publisher","first-page":"169","DOI":"10.3389\/fphar.2018.00169","volume":"9","author":"P Gangadaran","year":"2018","unstructured":"Gangadaran P, Hong CM, Ahn BC. An update on in vivo imaging of extracellular vesicles as drug delivery vehicles. Front Pharmacol. 2018;9:169.","journal-title":"Front Pharmacol"},{"key":"629_CR8","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.tcb.2016.11.003","volume":"27","author":"SLN Maas","year":"2017","unstructured":"Maas SLN, Breakefield XO, Weaver AM. Extracellular vesicles: unique intercellular delivery vehicles. Trends Cell Bio. 2017;27:172\u201388.","journal-title":"Trends Cell Bio"},{"key":"629_CR9","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1038\/s41419-020-02827-w","volume":"11","author":"W Dai","year":"2020","unstructured":"Dai W, Jin X, Han L, Huang H, Ji Z, Xu X, et al. Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt\/beta-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma. Cell Death Dis. 2020;11:743.","journal-title":"Cell Death Dis"},{"key":"629_CR10","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1111\/jop.12654","volume":"47","author":"J Hou","year":"2018","unstructured":"Hou J, Wang F, Liu X, Song M, Yin X. Tumor-derived exosomes enhance invasion and metastasis of salivary adenoid cystic carcinoma cells. J Oral Pathol Med. 2018;47:144\u201351.","journal-title":"J Oral Pathol Med"},{"key":"629_CR11","doi-asserted-by":"publisher","first-page":"1976","DOI":"10.1002\/cbin.11627","volume":"45","author":"L Chen","year":"2021","unstructured":"Chen L, Qin L, Chen C, Hu Q, Wang J, Shen J. Serum exosomes accelerate diabetic wound healing by promoting angiogenesis and ECM formation. Cell Bio Int. 2021;45:1976\u201385.","journal-title":"Cell Bio Int"},{"key":"629_CR12","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1080\/14728222.2018.1464141","volume":"22","author":"N Ludwig","year":"2018","unstructured":"Ludwig N, Whiteside TL. Potential roles of tumor-derived exosomes in angiogenesis. Expert Opin Ther Targets. 2018;22:409\u201317.","journal-title":"Expert Opin Ther Targets"},{"key":"629_CR13","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s10456-020-09728-8","volume":"23","author":"N Ludwig","year":"2020","unstructured":"Ludwig N, Yerneni SS, Azambuja JH, Gillespie DG, Menshikova EV, Jackson EK, et al. Tumor-derived exosomes promote angiogenesis via adenosine A(2B) receptor signaling. Angiogenesis. 2020;23:599\u2013610.","journal-title":"Angiogenesis"},{"key":"629_CR14","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.intimp.2019.04.020","volume":"72","author":"L Cao","year":"2019","unstructured":"Cao L, Xu H, Wang G, Liu M, Tian D, Yuan Z. Extracellular vesicles derived from bone marrow mesenchymal stem cells attenuate dextran sodium sulfate-induced ulcerative colitis by promoting M2 macrophage polarization. Int Immunopharmacol. 2019;72:264\u201374.","journal-title":"Int Immunopharmacol"},{"key":"629_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120954","volume":"275","author":"SW Kim","year":"2021","unstructured":"Kim SW, Im GB, Jeong GJ, Baik S, Hyun J, Kim YJ, et al. Delivery of a spheroids-incorporated human dermal fibroblast sheet increases angiogenesis and M2 polarization for wound healing. Biomaterials. 2021;275:120954.","journal-title":"Biomaterials"},{"key":"629_CR16","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.4049\/jimmunol.1700167","volume":"199","author":"H Shinohara","year":"2017","unstructured":"Shinohara H, Kuranaga Y, Kumazaki M, Sugito N, Yoshikawa Y, Takai T, et al. Regulated polarization of tumor-associated macrophages by miR-145 via colorectal cancer-derived extracellular vesicles. J Immunol. 2017;199:1505\u201315.","journal-title":"J Immunol"},{"key":"629_CR17","doi-asserted-by":"publisher","first-page":"4586","DOI":"10.1158\/0008-5472.CAN-17-3841","volume":"78","author":"X Wang","year":"2018","unstructured":"Wang X, Luo G, Zhang K, Cao J, Huang C, Jiang T, et al. Hypoxic tumor-derived exosomal miR-301a mediates M2 macrophage polarization via PTEN\/PI3Kgamma to promote pancreatic cancer metastasis. Cancer Res. 2018;78:4586\u201398.","journal-title":"Cancer Res"},{"key":"629_CR18","doi-asserted-by":"publisher","first-page":"3327","DOI":"10.1111\/bph.15052","volume":"177","author":"W Guo","year":"2020","unstructured":"Guo W, Qiu W, Ao X, Li W, He X, Ao L, et al. Low-concentration DMSO accelerates skin wound healing by Akt\/mTOR-mediated cell proliferation and migration in diabetic mice. Br J Pharmacol. 2020;177:3327\u201341.","journal-title":"Br J Pharmacol"},{"key":"629_CR19","doi-asserted-by":"publisher","first-page":"2594","DOI":"10.1038\/s41467-022-30197-8","volume":"13","author":"S Yuge","year":"2022","unstructured":"Yuge S, Nishiyama K, Arima Y, Hanada Y, Oguri-Nakamura E, Hanada S, et al. Mechanical loading of intraluminal pressure mediates wound angiogenesis by regulating the TOCA family of F-BAR proteins. Nat Commun. 2022;13:2594.","journal-title":"Nat Commun"},{"key":"629_CR20","doi-asserted-by":"publisher","first-page":"9837","DOI":"10.2147\/IJN.S228462","volume":"14","author":"AK Kar","year":"2019","unstructured":"Kar AK, Singh A, Dhiman N, Purohit P, Jagdale P, Kamthan M, et al. Polymer-assisted in situ synthesis of silver nanoparticles with epigallocatechin gallate (EGCG) impregnated wound patch potentiate controlled inflammatory responses for brisk wound healing. Int J Nanomed. 2019;14:9837\u201354.","journal-title":"Int J Nanomed"},{"key":"629_CR21","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.trsl.2021.05.006","volume":"236","author":"AE Louiselle","year":"2021","unstructured":"Louiselle AE, Niemiec SM, Zgheib C, Liechty KW. Macrophage polarization and diabetic wound healing. Transl Res. 2021;236:109\u201316.","journal-title":"Transl Res"},{"key":"629_CR22","doi-asserted-by":"publisher","first-page":"5348","DOI":"10.7150\/thno.27385","volume":"8","author":"S Zhang","year":"2018","unstructured":"Zhang S, Liu Y, Zhang X, Zhu D, Qi X, Cao X, et al. Prostaglandin E2 hydrogel improves cutaneous wound healing via M2 macrophages polarization. Theranostics. 2018;8:5348\u201361.","journal-title":"Theranostics"},{"key":"629_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2023.108435","volume":"37","author":"J Guo","year":"2023","unstructured":"Guo J, Jiang G, Chen J, Zhang M, Xiang K, Wang C, et al. Tumor tissue derived extracellular vesicles promote diabetic wound healing. J Diabetes Complicat. 2023;37:108435.","journal-title":"J Diabetes Complicat"},{"key":"629_CR24","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1186\/s12951-021-01113-x","volume":"19","author":"Y Ding","year":"2021","unstructured":"Ding Y, Li Y, Sun Z, Han X, Chen Y, Ge Y, et al. Cell-derived extracellular vesicles and membranes for tissue repair. J Nanobiotechnol. 2021;19:368.","journal-title":"J Nanobiotechnol"},{"key":"629_CR25","doi-asserted-by":"publisher","first-page":"C105","DOI":"10.1152\/ajpcell.00059.2020","volume":"319","author":"R Tang","year":"2020","unstructured":"Tang R, Wang YC, Mei X, Shi N, Sun C, Ran R, et al. LncRNA GAS5 attenuates fibroblast activation through inhibiting Smad3 signaling. Am J Physiol Cell Physiol. 2020;319:C105\u201315.","journal-title":"Am J Physiol Cell Physiol"},{"key":"629_CR26","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1111\/iwj.13248","volume":"17","author":"S Rabiee Motmaen","year":"2020","unstructured":"Rabiee Motmaen S, Tavakol S, Joghataei MT, Barati M. Acidic pH derived from cancer cells as a double-edged knife modulates wound healing through DNA repair genes and autophagy. Int Wound J. 2020;17:137\u201348.","journal-title":"Int Wound J"},{"key":"629_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.121269","volume":"280","author":"A Thibodeau","year":"2022","unstructured":"Thibodeau A, Galbraith T, Fauvel CM, Khuong HT, Berthod F. Repair of peripheral nerve injuries using a prevascularized cell-based tissue-engineered nerve conduit. Biomaterials. 2022;280: 121269.","journal-title":"Biomaterials"},{"key":"629_CR28","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.468","volume":"11","author":"X He","year":"2021","unstructured":"He X, Kuang G, Wu Y, Ou C. Emerging roles of exosomal miRNAs in diabetes mellitus. Clin Transl Med. 2021;11: e468.","journal-title":"Clin Transl Med"},{"key":"629_CR29","first-page":"196","volume":"8","author":"I Maligianni","year":"2021","unstructured":"Maligianni I, Yapijakis C, Bacopoulou F, Chrousos G. The potential role of exosomes in child and adolescent obesity. Children (Basel). 2021;8:196.","journal-title":"Children (Basel)"},{"key":"629_CR30","doi-asserted-by":"publisher","first-page":"e639","DOI":"10.1097\/CCM.0000000000001629","volume":"44","author":"M Chu","year":"2016","unstructured":"Chu M, Qin S, Wu R, Zhou X, Tang X, Zhang S, et al. Role of miR-126a-3p in endothelial injury in endotoxic mice. Crit Care Med. 2016;44:e639\u201350.","journal-title":"Crit Care Med"},{"key":"629_CR31","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1007\/s12033-021-00327-6","volume":"63","author":"C Huang","year":"2021","unstructured":"Huang C, Fang X, Xie X, Liu Y, Xu D, Meng X, et al. Effect of miR-126 on the proliferation and migration of vascular smooth muscle cells in aortic aneurysm mice under PI3K\/AKT\/mTOR signaling pathway. Mol Biotechnol. 2021;63:631\u20137.","journal-title":"Mol Biotechnol"},{"key":"629_CR32","doi-asserted-by":"publisher","first-page":"2148","DOI":"10.1111\/jcmm.16192","volume":"25","author":"L Zhang","year":"2021","unstructured":"Zhang L, Ouyang P, He G, Wang X, Song D, Yang Y, et al. Exosomes from microRNA-126 overexpressing mesenchymal stem cells promote angiogenesis by targeting the PIK3R2-mediated PI3K\/Akt signalling pathway. J Cell Mol Med. 2021;25:2148\u201362.","journal-title":"J Cell Mol Med"},{"key":"629_CR33","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3389\/fnmol.2011.00051","volume":"4","author":"J Karar","year":"2011","unstructured":"Karar J, Maity A. PI3K\/AKT\/mTOR pathway in angiogenesis. Front Mol Neurosci. 2011;4:51.","journal-title":"Front Mol Neurosci"},{"key":"629_CR34","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.659260","volume":"9","author":"X Shu","year":"2021","unstructured":"Shu X, Zhan PP, Sun LX, Yu L, Liu J, Sun LC, et al. BCAT1 activates PI3K\/AKT\/mTOR pathway and contributes to the angiogenesis and tumorigenicity of gastric cancer. Front Cell Dev Bio. 2021;9:659260.","journal-title":"Front Cell Dev Bio"},{"key":"629_CR35","doi-asserted-by":"publisher","first-page":"tkaa020","DOI":"10.1093\/burnst\/tkaa020","volume":"8","author":"P Wei","year":"2020","unstructured":"Wei P, Zhong C, Yang X, Shu F, Xiao S, Gong T, et al. Exosomes derived from human amniotic epithelial cells accelerate diabetic wound healing via PI3K-AKT-mTOR-mediated promotion in angiogenesis and fibroblast function. Burns Trauma. 2020;8:tkaa020.","journal-title":"Burns Trauma"},{"issue":"1","key":"629_CR36","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.jaad.2013.07.048","volume":"70","author":"A Alavi","year":"2014","unstructured":"Alavi A, Sibbald RG, Mayer D, Goodman L, Bortos M, Armstrong DG, et al. Diabetic foot ulcers: part I. Pathophysiology and prevention. J Am Acad Dermatol. 2014;70(1):e1-18.","journal-title":"J Am Acad Dermatol"},{"key":"629_CR37","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1016\/j.jdiacomp.2014.04.011","volume":"28","author":"D Martins-Mendes","year":"2014","unstructured":"Martins-Mendes D, Monteiro-Soares M, Boyko EJ, Ribeiro M, Barata P, Lima J, et al. The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk. J Diabetes Complicat. 2014;28:632\u20138.","journal-title":"J Diabetes Complicat"},{"key":"629_CR38","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s40265-020-01415-8","volume":"81","author":"D Dixon","year":"2021","unstructured":"Dixon D, Edmonds M. Managing diabetic foot ulcers: pharmacotherapy for wound healing. Drugs. 2021;81:29\u201356.","journal-title":"Drugs"},{"key":"629_CR39","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.3390\/ijms18071419","volume":"18","author":"UA Okonkwo","year":"2017","unstructured":"Okonkwo UA, DiPietro LA. Diabetes and wound angiogenesis. Int J Mol Sci. 2017;18:1419.","journal-title":"Int J Mol Sci"},{"key":"629_CR40","doi-asserted-by":"publisher","first-page":"16885","DOI":"10.1002\/jcp.28374","volume":"234","author":"C Aslan","year":"2019","unstructured":"Aslan C, Maralbashi S, Salari F, Kahroba H, Sigaroodi F, Kazemi T, et al. Tumor-derived exosomes: Implication in angiogenesis and antiangiogenesis cancer therapy. J Cell Physiol. 2019;234:16885\u2013903.","journal-title":"J Cell Physiol"},{"key":"629_CR41","doi-asserted-by":"publisher","DOI":"10.1172\/JCI144871","volume":"131","author":"L El-Houjeiri","year":"2021","unstructured":"El-Houjeiri L, Biondini M, Paquette M, Kuasne H, Pacis A, Park M, et al. Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis. J Clin Invest. 2021;131: e144871.","journal-title":"J Clin Invest"},{"key":"629_CR42","doi-asserted-by":"publisher","first-page":"3606","DOI":"10.1038\/s41467-020-17384-1","volume":"11","author":"C Nuevo-Tapioles","year":"2020","unstructured":"Nuevo-Tapioles C, Santacatterina F, Stamatakis K, Nunez de Arenas C, Gomez de Cedron M, et al. Coordinate beta-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth. Nat Commun. 2020;11:3606.","journal-title":"Nat Commun"},{"key":"629_CR43","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1159\/000516498","volume":"58","author":"R Manjunathan","year":"2021","unstructured":"Manjunathan R, Devarajan N, Ragunathan M. Possible mechanism of human recombinant leptin-induced VEGF A synthesis via PI3K\/Akt\/mTOR\/S6 kinase signaling pathway while inducing angiogenesis: an analysis using chicken chorioallantoic membrane model. J Vasc Res. 2021;58:343\u201360.","journal-title":"J Vasc Res"},{"key":"629_CR44","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114670","volume":"193","author":"T Liu","year":"2023","unstructured":"Liu T, Lu Y, Zhan R, Qian W, Luo G. Nanomaterials and nanomaterials-based drug delivery to promote cutaneous wound healing. Adv Drug Deliv Rev. 2023;193: 114670.","journal-title":"Adv Drug Deliv Rev"},{"key":"629_CR45","doi-asserted-by":"publisher","first-page":"8790","DOI":"10.3390\/ijms21228790","volume":"21","author":"M Piipponen","year":"2020","unstructured":"Piipponen M, Li D, Landen NX. The immune functions of keratinocytes in skin wound healing. Int J Mol Sci. 2020;21:8790.","journal-title":"Int J Mol Sci"},{"key":"629_CR46","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.116310","volume":"241","author":"S Veeraperumal","year":"2020","unstructured":"Veeraperumal S, Qiu HM, Zeng SS, Yao WZ, Wang BP, Liu Y, et al. Polysaccharides from Gracilaria lemaneiformis promote the HaCaT keratinocytes wound healing by polarised and directional cell migration. Carbohydr Polym. 2020;241: 116310.","journal-title":"Carbohydr Polym"},{"key":"629_CR47","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.addr.2018.09.010","volume":"146","author":"AP Veith","year":"2019","unstructured":"Veith AP, Henderson K, Spencer A, Sligar AD, Baker AB. Therapeutic strategies for enhancing angiogenesis in wound healing. Adv Drug Deliv Rev. 2019;146:97\u2013125.","journal-title":"Adv Drug Deliv Rev"},{"key":"629_CR48","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1007\/s00418-018-1752-z","volume":"151","author":"M Lee","year":"2019","unstructured":"Lee M, Lee D, Jung H. Wound healing mechanism in Mongolian gerbil skin. Histochem Cell Biol. 2019;151:229\u201338.","journal-title":"Histochem Cell Biol"},{"key":"629_CR49","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1186\/s13287-019-1415-6","volume":"10","author":"H Bi","year":"2019","unstructured":"Bi H, Li H, Zhang C, Mao Y, Nie F, Xing Y, et al. Stromal vascular fraction promotes migration of fibroblasts and angiogenesis through regulation of extracellular matrix in the skin wound healing process. Stem Cell Res Ther. 2019;10:302.","journal-title":"Stem Cell Res Ther"},{"key":"629_CR50","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.bbrc.2018.04.067","volume":"500","author":"L Zhou","year":"2018","unstructured":"Zhou L, Wang H, Jing J, Yu L, Wu X, Lu Z. Regulation of hair follicle development by exosomes derived from dermal papilla cells. Biochem Biophys Res Commun. 2018;500:325\u201332.","journal-title":"Biochem Biophys Res Commun"},{"key":"629_CR51","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1111\/wrr.12759","volume":"28","author":"X Hu","year":"2020","unstructured":"Hu X, Zhang H, Li X, Li Y, Chen Z. Activation of mTORC1 in fibroblasts accelerates wound healing and induces fibrosis in mice. Wound Repair Regen. 2020;28:6\u201315.","journal-title":"Wound Repair Regen"},{"key":"629_CR52","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.652322","volume":"9","author":"Y Cui","year":"2021","unstructured":"Cui Y, Wang D, Xie M. Tumor-derived extracellular vesicles promote activation of carcinoma-associated fibroblasts and facilitate invasion and metastasis of ovarian cancer by carrying miR-630. Front Cell Dev Biol. 2021;9: 652322.","journal-title":"Front Cell Dev Biol"},{"key":"629_CR53","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1038\/s41419-021-04446-5","volume":"13","author":"B Li","year":"2022","unstructured":"Li B, Chen Y, Liang L, Wang Y, Huang W, Zhao K, et al. Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1\/miR-556-3p\/CLIC1 axis. Cell Death Dis. 2022;13:217.","journal-title":"Cell Death Dis"},{"key":"629_CR54","doi-asserted-by":"publisher","first-page":"14450","DOI":"10.1038\/ncomms14450","volume":"8","author":"Q Feng","year":"2017","unstructured":"Feng Q, Zhang C, Lum D, Druso JE, Blank B, Wilson KF, et al. A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis. Nat Commun. 2017;8:14450.","journal-title":"Nat Commun"},{"key":"629_CR55","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.canlet.2021.10.023","volume":"524","author":"M Huang","year":"2022","unstructured":"Huang M, Liu M, Huang D, Ma Y, Ye G, Wen Q, et al. Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6\/Axl pathway. Cancer Lett. 2022;524:131\u201343.","journal-title":"Cancer Lett"},{"key":"629_CR56","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.737449","volume":"9","author":"NL Santos","year":"2021","unstructured":"Santos NL, Bustos SO, Bhatt D, Chammas R, Andrade LNS. Tumor-derived extracellular vesicles: modulation of cellular functional dynamics in tumor microenvironment and its clinical implications. Front Cell Dev Biol. 2021;9: 737449.","journal-title":"Front Cell Dev Biol"},{"key":"629_CR57","doi-asserted-by":"publisher","first-page":"639","DOI":"10.2217\/imt-2022-0036","volume":"14","author":"SA Sadeghi Najafabadi","year":"2022","unstructured":"Sadeghi Najafabadi SA, Bolhassani A, Aghasadeghi MR. Tumor cell-based vaccine: an effective strategy for eradication of cancer cells. Immunotherapy. 2022;14:639\u201354.","journal-title":"Immunotherapy"},{"key":"629_CR58","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1038\/mt.2008.1","volume":"16","author":"S Dan","year":"2008","unstructured":"Dan S, Wei D, Wu Z, Zhou X, Wei X, Huang H, et al. Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer. Mol Ther. 2008;16:782\u201390.","journal-title":"Mol Ther"}],"container-title":["Tissue Engineering and Regenerative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13770-024-00629-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s13770-024-00629-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13770-024-00629-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T17:13:35Z","timestamp":1715361215000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s13770-024-00629-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,12]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["629"],"URL":"https:\/\/doi.org\/10.1007\/s13770-024-00629-1","relation":{},"ISSN":["1738-2696","2212-5469"],"issn-type":[{"value":"1738-2696","type":"print"},{"value":"2212-5469","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,12]]},"assertion":[{"value":"10 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 March 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors report no conflicts of interest in this work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures were carried out in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals and were approved by the Committee on the Ethics of Animal Experiments at Xinxiang Medical University (approval no, XYLL-20210252).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical statement"}}]}}