{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T16:31:54Z","timestamp":1779121914406,"version":"3.51.4"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infection"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Berlin is amongst the cities most affected by the current monkeypox outbreak. Here, we report clinical characteristics of the first patients with confirmed monkeypox admitted to our center. We analyzed anamnestic, clinical, and laboratory data. Within a period of 2\u00a0weeks, six patients were hospitalized in our unit. All were MSM and had practiced condomless receptive anal intercourse in the weeks preceding admission. The chief complaint in all patients but one was severe anal pain unprecedented in severity. Investigations revealed proctitis, as well as anal and rectal ulcers with detection of monkeypox virus. Our findings support the hypothesis that sexual transmission plays a role in the current outbreak.<\/jats:p>","DOI":"10.1007\/s15010-022-01896-7","type":"journal-article","created":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T12:05:44Z","timestamp":1660305944000},"page":"483-487","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Monkeypox in-patients with severe anal pain"],"prefix":"10.1007","volume":"51","author":[{"given":"Frieder","family":"Pf\u00e4fflin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Wendisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Scherer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"J\u00fcrgens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gis\u00e8le","family":"Godzick-Njomgang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Tranter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinkus","family":"Tober-Lau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam Songa","family":"Stegemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor Max","family":"Corman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3807-473X","authenticated-orcid":false,"given":"Florian","family":"Kurth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Sch\u00fcrmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,8,12]]},"reference":[{"key":"1896_CR1","unstructured":"UK Health Security Agency. 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Accessed 21 Jul 2022."},{"key":"1896_CR4","unstructured":"MPX - Affenpocken [Internet]. 2022 [cited 2022 Jul 21]. https:\/\/www.berlin.de\/lageso\/gesundheit\/infektionskrankheiten\/affenpocken\/. Accessed 21 Jul 2022."},{"key":"1896_CR5","first-page":"e210","volume":"71","author":"D Ogoina","year":"2020","unstructured":"Ogoina D, Iroezindu M, James HI, Oladokun R, Yinka-Ogunleye A, Wakama P, et al. Clinical course and outcome of human monkeypox in Nigeria. Clin Infect Dis Oxford University Press (OUP). 2020;71:e210\u20134.","journal-title":"Clin Infect Dis Oxford University Press (OUP)"},{"key":"1896_CR6","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1016\/S1473-3099(22)00228-6","volume":"22","author":"H Adler","year":"2022","unstructured":"Adler H, Gould S, Hine P, Snell LB, Wong W, Houlihan CF, et al. Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis Elsevier BV. 2022;22:1153\u201362.","journal-title":"Lancet Infect Dis Elsevier BV"},{"key":"1896_CR7","doi-asserted-by":"publisher","DOI":"10.1101\/2022.05.26.22273379","author":"PR Pittman","year":"2022","unstructured":"Pittman PR, Martin JW, Kingebeni PM, Tamfum J-JM, Wan Q, Reynolds MG, et al. Clinical characterization of human monkeypox infections in the Democratic Republic of the Congo. bioRxiv. 2022. https:\/\/doi.org\/10.1101\/2022.05.26.22273379.","journal-title":"bioRxiv"},{"key":"1896_CR8","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2022.27.22.2200421","author":"A Antinori","year":"2022","unstructured":"Antinori A, Mazzotta V, Vita S, Carletti F, Tacconi D, Lapini LE, et al. Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. Euro Surveill [Internet]. European Centre for Disease Control and Prevention (ECDC). 2022. https:\/\/doi.org\/10.2807\/1560-7917.ES.2022.27.22.2200421.","journal-title":"European Centre for Disease Control and Prevention (ECDC)"},{"key":"1896_CR9","doi-asserted-by":"publisher","DOI":"10.1101\/2022.07.04.22277226","author":"I De Baetselier","year":"2022","unstructured":"De Baetselier I, Van Dijck C, Kenyon C, Coppens J, Van den Bossche D, Smet H, et al. Asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium. bioRxiv. 2022. https:\/\/doi.org\/10.1101\/2022.07.04.22277226.","journal-title":"bioRxiv"},{"key":"1896_CR10","unstructured":"Emergency Response. Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 [Internet]. World Health Organization; 2022. https:\/\/www.who.int\/publications\/i\/item\/WHO-MPX-Clinical-and-IPC-2022.1. Accessed 21 Jul 2022"}],"container-title":["Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s15010-022-01896-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s15010-022-01896-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s15010-022-01896-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T10:16:17Z","timestamp":1679912177000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s15010-022-01896-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,12]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["1896"],"URL":"https:\/\/doi.org\/10.1007\/s15010-022-01896-7","relation":{},"ISSN":["0300-8126","1439-0973"],"issn-type":[{"value":"0300-8126","type":"print"},{"value":"1439-0973","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,12]]},"assertion":[{"value":"5 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2022","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Missing Open Access funding information has been added in the Funding Note.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"On behalf of all authors, the corresponding author states that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}},{"value":"Informed consent was obtained from all individual participants included in the study. Patients signed informed consent regarding publishing their data and, where applicable, photograph.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}