{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:35:10Z","timestamp":1789086910183,"version":"build-2803163510"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005758","name":"Universit\u00e0 Politecnica delle Marche","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005758","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infection"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Dengue is the most common arboviral disease globally. It is caused by four distinct but closely related Dengue viruses (DENV-1, -2, -3, and \u2212\u20094) transmitted through bites of infected Aedes species mosquito vectors. In the last 50 years, incidence has increased 30-fold with increasing geographic expansion to new countries. Here we report the most important autochthonous Dengue epidemic in Italy ever recorded with a total of 86 confirmed cases occurring in September 2024 in Fano. They were caused by DENV-2. They were 61 Dengue fever, 21 Dengue with warning signs and no cases of severe Dengue. Our data underline the importance of considering Dengue not only as imported disease and rapidly testing all those patients with suggestive clinical pictures even if they have no travel history.<\/jats:p>","DOI":"10.1007\/s15010-025-02476-1","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T14:10:57Z","timestamp":1738246257000},"page":"1213-1218","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Outbreak of autochthonous dengue in Fano, Pesaro-Urbino Province - Marche region, Italy, September 2024"],"prefix":"10.1007","volume":"53","author":[{"given":"Luca","family":"Santilli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Canovari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Balducci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Corbelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monia","family":"Maracci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Polenta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ylenia","family":"Farinaccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Ginevri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma","family":"Anzalone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Franca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Sterza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Barchiesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"key":"2476_CR1","unstructured":"World Health Organization. Disease Outbreak News; Dengue\u2013 Global situation. May 30, 2024."},{"key":"2476_CR2","unstructured":"CDC\u2013 Emergency Preparedness and Response -. Increased risk of Dengue Virus Infections in the United States -. CDC Health Alert Netw June 25, 2024."},{"key":"2476_CR3","unstructured":"Dengue guidelines. for diagnosis, treatment, prevention and control - A joint publication of the World Health Organization (WHO) and the Special Programme for Research and Training in Tropical Diseases (TDR)\u2013\u200921 April 2009 - Technical document - Control of Neglected Tropical Diseases (NTD), Emergency Preparedness (WPE) Editors - WHO Department of control of neglected tropical diseases and TDR - ISBN: 978 92 4 154787 1 - WHO Reference Number: WHO\/HTM\/NTD\/DEN\/2009.1."},{"key":"2476_CR4","doi-asserted-by":"publisher","unstructured":"Reeves WC, Hardy JL, Reisen WK, Milby MM. Potential effect of global warming on mosquito-borne arboviruses. J Med Entomol. 1994;31(3):323\u2013\u200932. https:\/\/doi.org\/10.1093\/jmedent\/31.3.323. PMID: 8057305.","DOI":"10.1093\/jmedent\/31.3.323"},{"issue":"7","key":"2476_CR5","doi-asserted-by":"publisher","first-page":"e0007528","DOI":"10.1371\/journal.pntd.0007528","volume":"13","author":"P Jia","year":"2019","unstructured":"Jia P, Liang L, Tan X, Chen J, Chen X. Potential effects of heat waves on the population dynamics of the dengue mosquito Aedes albopictus. PLoS Negl Trop Dis. 2019;13(7):e0007528. https:\/\/doi.org\/10.1371\/journal.pntd.0007528. PMID: 31276467; PMCID: PMC6645582.","journal-title":"PLoS Negl Trop Dis"},{"key":"2476_CR6","unstructured":"Italian Ministry of Health. Piano Nazionale di prevenzione, sorveglianza e risposta alle Arbovirosi (PNA) 2020\u20132025. [National plan for prevention, surveillance and response to arboviruses 2020\u20132025]. Rome: Ministry of Health. 2019. Italian. Available from: https:\/\/www.salute.gov.it\/imgs\/C_17_pubblicazioni_2947_allegato.pdf"},{"issue":"47","key":"2476_CR7","doi-asserted-by":"publisher","first-page":"2400713","DOI":"10.2807\/1560-7917.ES.2024.29.47.2400713","volume":"29","author":"C Sacco","year":"2024","unstructured":"Sacco C, Liverani A, Venturi G, Gavaudan S, Riccardo F, Salvoni G, Fortuna C, Marinelli K, Marsili G, Pesaresi A, Gran\u00e9 CM, Mercuri I, Manica M, Caucci S, Morelli D, Sebastianelli L, Marcacci M, Ferraro F, Di Luca M, Pascucci I, Merakou C, Duranti A, Pati I, Lombardini L, Fiacchini D, Filipponi G, Maraglino F, Palamara AT, Poletti P, Pezzotti P, Filippetti F, Merler S, Del Manso M, Menzo S. Marche dengue outbreak group. Autochthonous dengue outbreak in Marche Region, Central Italy, August to October 2024. Euro Surveill. 2024;29(47):2400713. https:\/\/doi.org\/10.2807\/1560-7917.ES.2024.29.47.2400713. 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Dengue virus transmission in Italy: historical trends up to 2023 and a data repository into the future. Sci Data. 2024;11(1):1325. https:\/\/doi.org\/10.1038\/s41597-024-04162-7. PMID: 39639007; PMCID: PMC11621350.","journal-title":"Sci Data"},{"issue":"36","key":"2476_CR11","doi-asserted-by":"publisher","first-page":"pii","DOI":"10.2807\/1560-7917.ES.2020.25.36.2001606","volume":"25","author":"B Lazzarini Luca","year":"2020","unstructured":"Lazzarini Luca B, Luisa F, Felice M, Vinicio P, Monia P, Giacomina R, Mario C, Gioia M, Fabrizio M, Simone. Zanella Francesca, Padovan Maria Teresa, Russo Francesca, Gobbi Federico. First autochthonous dengue outbreak in Italy, August 2020. 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Euro Surveill. 2023;28(44):pii\u2013. https:\/\/doi.org\/10.2807\/1560-7917.ES.2023.28.44.2300552.","journal-title":"Euro Surveill"},{"key":"2476_CR14","doi-asserted-by":"publisher","unstructured":"Salvo PF, Baldin G, Raffaelli F, Ciccullo A, Borghetti A, Tamburrini E, Ricci R, Di Donato M, Di Giambenedetto S, Torti C. Autochthonous dengue outbreak in Rome, Italy, in 2023. J Travel Med. 2024;31(7):taae111. https:\/\/doi.org\/10.1093\/jtm\/taae111. PMID: 39180338.","DOI":"10.1093\/jtm\/taae111"},{"issue":"1","key":"2476_CR15","doi-asserted-by":"publisher","first-page":"183","DOI":"10.3201\/eid3001.231508","volume":"30","author":"S Vita","year":"2024","unstructured":"Vita S, Bordi L, Sberna G, Caputi P, Lapa D, Corpolongo A, Mija C, D\u2019Abramo A, Maggi F, Vairo F, Specchiarello E, Girardi E, Lalle E, Nicastri E. Autochthonous Dengue Fever in 2 patients, Rome, Italy. Emerg Infect Dis. 2024;30(1):183\u20134. Epub 2023 Nov 15. 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Travel Med Infect Dis. 2024 Nov-Dec;62:102762. https:\/\/doi.org\/10.1016\/j.tmaid.2024.102762. Epub 2024 Sep 19. PMID: 39306188.","DOI":"10.1016\/j.tmaid.2024.102762"},{"issue":"1","key":"2476_CR22","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3390\/tropicalmed7010010","volume":"7","author":"M Ricc\u00f2","year":"2022","unstructured":"Ricc\u00f2 M, Peruzzi S, Balzarini F, Zaniboni A, Ranzieri S. Dengue fever in Italy: the eternal return of an emerging Arboviral Disease. Trop Med Infect Dis. 2022;7(1):10. https:\/\/doi.org\/10.3390\/tropicalmed7010010. PMID: 35051126; PMCID: PMC8782038.","journal-title":"Trop Med Infect Dis"},{"key":"2476_CR23","doi-asserted-by":"publisher","unstructured":"Faburay B. The case for a \u2018one health\u2019 approach to combating vector-borne diseases. 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