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Our study prospectively assessed severe acute respiratory infections, their causative pathogens, and the resulting disease burden on German children's hospitals for the fall\/winter 2023\u20132024 season.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From October 3, 2023 through April 16, 2024, children hospitalized with ARI as a primary diagnosis were monitored via a national survey established by the German Society for Pediatric Infectious Diseases (DGPI). Weekly data was collected on total hospital admissions, ARI-related admissions by pathogen (SARS-CoV-2, RSV, influenza, other), ICU admissions with ARI as a primary diagnosis, and respiratory support.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 23% of German children's hospitals (77\/334 centers) submitted 1234 survey reports. ARI-related hospital admissions surged starting in November 2023 and peaked in late December 2023 (53.4% of all admissions), in parallel with a peak in the average number of newly-admitted patients (aNA) with RSV (2.5 aNA). In comparison to the 2022\/2023 season, fewer newborns and infants were admitted for ARI (4.7%, p\u2009&lt;\u20090.001\/1.9%, p\u2009=\u20090.05) and fewer required ICU treatment (5.3%, p\u2009=\u20090.02\/5.6%, p\u2009=\u20090.001 respectively). In 74.9% of ICU patients, ventilation support was required\u20149.1% less than in the previous season.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The clinical burden on pediatric hospitals and ICUs is strongly influenced by the changing, annually circulating pathogens and affected age group. Therefore, a continuous, systematic, dynamic collection of ARI data is critical for assessing the ARI-related morbidity and the associated burden on health care systems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s15010-025-02494-z","type":"journal-article","created":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T22:48:16Z","timestamp":1741646896000},"page":"717-725","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Persistently high burden of acute respiratory infections requiring hospitalization in German pediatric hospitals, fall\/winter 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