{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T19:49:54Z","timestamp":1774554594714,"version":"3.50.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infection"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s15010-025-02692-9","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T09:12:26Z","timestamp":1764321146000},"page":"991-1000","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Melioidosis imported to Northern Germany: a case report series"],"prefix":"10.1007","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8980-3149","authenticated-orcid":false,"given":"Dorothea","family":"Ekoka Mbassi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8944-8498","authenticated-orcid":false,"given":"Aiman Gamal","family":"Abdelrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9714-0725","authenticated-orcid":false,"given":"Ilka","family":"Grewe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6129-0725","authenticated-orcid":false,"given":"Pia M.","family":"Michelitsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0760-1068","authenticated-orcid":false,"given":"Annette","family":"Hennigs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5118-9523","authenticated-orcid":false,"given":"Flaminia","family":"Olearo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2836-9224","authenticated-orcid":false,"given":"Marylyn M.","family":"Addo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9259-1885","authenticated-orcid":false,"given":"Michael","family":"Ramharter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2984-9704","authenticated-orcid":false,"given":"Sabine","family":"Jordan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6910-8461","authenticated-orcid":false,"given":"Stefan","family":"Schmiedel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"issue":"5","key":"2692_CR1","doi-asserted-by":"publisher","first-page":"327","DOI":"10.31128\/AJGP-04-18-4558","volume":"48","author":"A Chakravorty","year":"2019","unstructured":"Chakravorty A, Heath CH. Melioidosis: an updated review. Aust J Gen Pract. 2019;48(5):327\u201332. https:\/\/doi.org\/10.31128\/AJGP-04-18-4558","journal-title":"Aust J Gen Pract"},{"issue":"4","key":"2692_CR2","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s40475-017-0124-4","volume":"4","author":"AJ Merritt","year":"2017","unstructured":"Merritt AJ, Inglis TJJ. The role of climate in the epidemiology of melioidosis. Curr Trop Med Rep. 2017;4(4):185\u201391. https:\/\/doi.org\/10.1007\/s40475-017-0124-4","journal-title":"Curr Trop Med Rep"},{"issue":"25","key":"2692_CR3","doi-asserted-by":"publisher","first-page":"2355","DOI":"10.1056\/NEJMoa2306448","volume":"389","author":"JK Petras","year":"2023","unstructured":"Petras JK, Elrod MG, Ty MC, Dawson P, O\u2019Laughlin K, Gee JE, et al. Locally acquired melioidosis linked to environment - Mississippi, 2020\u20132023. N Engl J Med. 2023;389(25):2355\u201362. https:\/\/doi.org\/10.1056\/NEJMoa2306448","journal-title":"N Engl J Med"},{"key":"2692_CR4","doi-asserted-by":"publisher","first-page":"17107","DOI":"10.1038\/nrdp.2017.107","volume":"4","author":"WJ Wiersinga","year":"2018","unstructured":"Wiersinga WJ, Virk HS, Torres AG, Currie BJ, Peacock SJ, Dance DAB, et al. Melioidosis. Nat Rev Dis Primers. 2018;4:17107. https:\/\/doi.org\/10.1038\/nrdp.2017.107","journal-title":"Nat Rev Dis Primers"},{"issue":"2","key":"2692_CR5","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1128\/CMR.18.2.383-416.2005","volume":"18","author":"AC Cheng","year":"2005","unstructured":"Cheng AC, Currie BJ. Melioidosis: epidemiology, pathophysiology, and management. Clin Microbiol Rev. 2005;18(2):383\u2013416. https:\/\/doi.org\/10.1128\/CMR.18.2.383-416.2005","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"2692_CR6","doi-asserted-by":"publisher","first-page":"6","DOI":"10.7861\/clinmed.2022-0014","volume":"22","author":"P Karunanayake","year":"2022","unstructured":"Karunanayake P. Melioidosis: clinical aspects. Clin Med (Lond). 2022;22(1):6\u20138. https:\/\/doi.org\/10.7861\/clinmed.2022-0014","journal-title":"Clin Med (Lond)"},{"key":"2692_CR7","doi-asserted-by":"publisher","first-page":"e02407","DOI":"10.1016\/j.idcr.2025.e02407","volume":"42","author":"I Grewe","year":"2025","unstructured":"Grewe I, Hennigs A, Olearo F, Addo MM, Ramharter M, Jordan S. Melioidosis clinically unresponsive to meropenem in a traveller returning from Thailand. IDCases. 2025;42:e02407. https:\/\/doi.org\/10.1016\/j.idcr.2025.e02407","journal-title":"IDCases"},{"issue":"02","key":"2692_CR8","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1055\/s-0043-105318","volume":"24","author":"L Roggelin","year":"2017","unstructured":"Roggelin L, Jordan S, Ittrich H, Schmiedel S. Reiser\u00fcckkehrer Mit melioidose Aus Thailand. Flugmedizin \u00b7 Tropenmedizin \u00b7. Reisemedizin - FTR. 2017;24(02):62\u20135. https:\/\/doi.org\/10.1055\/s-0043-105318","journal-title":"Reisemedizin - FTR"},{"key":"2692_CR9","doi-asserted-by":"publisher","first-page":"16263","DOI":"10.1038\/nmicrobiol.2016.263","volume":"2","author":"C Chewapreecha","year":"2017","unstructured":"Chewapreecha C, Holden MT, Vehkala M, Valimaki N, Yang Z, Harris SR, et al. Global and regional dissemination and evolution of Burkholderia pseudomallei. Nat Microbiol. 2017;2:16263. https:\/\/doi.org\/10.1038\/nmicrobiol.2016.263","journal-title":"Nat Microbiol"},{"issue":"8","key":"2692_CR10","doi-asserted-by":"publisher","first-page":"e329","DOI":"10.1016\/S2542-5196(18)30165-7","volume":"2","author":"LYA Chai","year":"2018","unstructured":"Chai LYA, Fisher D. Earth, wind, rain, and melioidosis. Lancet Planet Health. 2018;2(8):e329\u201330. https:\/\/doi.org\/10.1016\/S2542-5196(18)30165-7","journal-title":"Lancet Planet Health"},{"issue":"3","key":"2692_CR11","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1038\/s41579-023-00972-5","volume":"22","author":"EM Meumann","year":"2024","unstructured":"Meumann EM, Limmathurotsakul D, Dunachie SJ, Wiersinga WJ, Currie BJ. Burkholderia pseudomallei and melioidosis. Nat Rev Microbiol. 2024;22(3):155\u201369. https:\/\/doi.org\/10.1038\/s41579-023-00972-5","journal-title":"Nat Rev Microbiol"},{"issue":"2","key":"2692_CR12","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3109\/00313026909061049","volume":"1","author":"RC Newland","year":"1969","unstructured":"Newland RC. Chronic melioidosis: a case in Sydney. Pathology. 1969;1(2):149\u201352. https:\/\/doi.org\/10.3109\/00313026909061049","journal-title":"Pathology"},{"issue":"11","key":"2692_CR13","doi-asserted-by":"publisher","first-page":"e900","DOI":"10.1371\/journal.pntd.0000900","volume":"4","author":"BJ Currie","year":"2010","unstructured":"Currie BJ, Ward L, Cheng AC. The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study. PLoS Negl Trop Dis. 2010;4(11):e900. https:\/\/doi.org\/10.1371\/journal.pntd.0000900","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"2692_CR14","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1128\/JCM.02239-13","volume":"52","author":"DS Sarovich","year":"2014","unstructured":"Sarovich DS, Ward L, Price EP, Mayo M, Pitman MC, Baird RW, et al. Recurrent melioidosis in the Darwin prospective melioidosis study: improving therapies mean that relapse cases are now rare. J Clin Microbiol. 2014;52(2):650\u20133. https:\/\/doi.org\/10.1128\/JCM.02239-13","journal-title":"J Clin Microbiol"},{"issue":"1","key":"2692_CR15","doi-asserted-by":"publisher","first-page":"22","DOI":"10.25259\/NMJI_402_2022","volume":"37","author":"V Ganesan","year":"2024","unstructured":"Ganesan V, Sundaramurthy R. Epidemiology and clinical spectrum of melioidosis: analysis of cases from a tertiary care centre in Southern Tamil Nadu. Natl Med J India. 2024;37(1):22\u20135. https:\/\/doi.org\/10.25259\/NMJI_402_2022","journal-title":"Natl Med J India"},{"issue":"12","key":"2692_CR16","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1016\/S1473-3099(21)00022-0","volume":"21","author":"BJ Currie","year":"2021","unstructured":"Currie BJ, Mayo M, Ward LM, Kaestli M, Meumann EM, Webb JR, et al. The Darwin prospective melioidosis study: a 30-year prospective, observational investigation. Lancet Infect Dis. 2021;21(12):1737\u201346. https:\/\/doi.org\/10.1016\/S1473-3099(21)00022-0","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"2692_CR17","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/s0035-9203(00)90333-x","volume":"94","author":"BJ Currie","year":"2000","unstructured":"Currie BJ, Fisher DA, Anstey NM, Jacups SP. Melioidosis: acute and chronic disease, relapse and re-activation. Trans R Soc Trop Med Hyg. 2000;94(3):301\u20134. https:\/\/doi.org\/10.1016\/s0035-9203(00)90333-x","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"5","key":"2692_CR18","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.3390\/ph3051296","volume":"3","author":"TJ Inglis","year":"2010","unstructured":"Inglis TJ. The treatment of melioidosis. Pharmaceuticals (Basel). 2010;3(5):1296\u2013303. https:\/\/doi.org\/10.3390\/ph3051296","journal-title":"Pharmaceuticals (Basel)"},{"key":"2692_CR19","doi-asserted-by":"publisher","unstructured":"Hoffmaster AR, AuCoin D, Baccam P, Baggett HC, Baird R, Bhengsri S, et al. Melioidosis diagnostic workshop, 2013. Emerg Infect Dis. 2015;21(2). https:\/\/doi.org\/10.3201\/eid2102.141045","DOI":"10.3201\/eid2102.141045"},{"issue":"1","key":"2692_CR20","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1093\/bmb\/ldr007","volume":"99","author":"D Limmathurotsakul","year":"2011","unstructured":"Limmathurotsakul D, Peacock SJ. Melioidosis: a clinical overview. Br Med Bull. 2011;99(1):125\u201339. https:\/\/doi.org\/10.1093\/bmb\/ldr007","journal-title":"Br Med Bull"},{"key":"2692_CR21","doi-asserted-by":"publisher","unstructured":"Sullivan RP, Marshall CS, Anstey NM, Ward L, Currie BJ. 2020 review and revision of the 2015 Darwin melioidosis treatment guideline; paradigm drift not shift. PLoS Negl Trop Dis. 2020;14(9):e0008659. https:\/\/doi.org\/10.1371\/journal.pntd.0008659","DOI":"10.1371\/journal.pntd.0008659"},{"issue":"6","key":"2692_CR22","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.apjtm.2016.04.003","volume":"9","author":"PV Kingsley","year":"2016","unstructured":"Kingsley PV, Arunkumar G, Tipre M, Leader M, Sathiakumar N. Pitfalls and optimal approaches to diagnose melioidosis. Asian Pac J Trop Med. 2016;9(6):515\u201324. https:\/\/doi.org\/10.1016\/j.apjtm.2016.04.003","journal-title":"Asian Pac J Trop Med"},{"issue":"7","key":"2692_CR23","doi-asserted-by":"publisher","first-page":"647","DOI":"10.3390\/antibiotics14070647","volume":"14","author":"J Thanasai","year":"2025","unstructured":"Thanasai J, Laklaeng SN, Khemla S, Ratanavong K, Chatatikun M, Tangpong J, et al. Global prevalence of antibiotic-resistant burkholderia pseudomallei in melioidosis patients: a systematic review and meta-analysis. Antibiot (Basel). 2025;14(7):647. https:\/\/doi.org\/10.3390\/antibiotics14070647","journal-title":"Antibiot (Basel)"},{"key":"2692_CR24","doi-asserted-by":"publisher","unstructured":"Gassiep I, Armstrong M, Norton R. Human melioidosis. Clin Microbiol Rev. 2020;33(2). https:\/\/doi.org\/10.1128\/CMR.00006-19","DOI":"10.1128\/CMR.00006-19"},{"key":"2692_CR25","unstructured":"European Committee on Antimicrobial Susceptibility Testing (EUCAST). EUCAST Clinical Breakpoint Tables v.15.0. (2025). https:\/\/www.eucast.org Accessed 17-10-2025 2025."},{"issue":"3","key":"2692_CR26","doi-asserted-by":"publisher","first-page":"783","DOI":"10.47665\/tb.37.3.783","volume":"37","author":"A Zamani","year":"2020","unstructured":"Zamani A, Zueter AR, Muhd Besari A, Hasan H, Harun A, Deris ZZ. Reduced susceptibility of Burkholderia pseudomallei following exposure to carbapenem. Trop Biomed. 2020;37(3):783\u201390. https:\/\/doi.org\/10.47665\/tb.37.3.783","journal-title":"Trop Biomed"},{"issue":"2","key":"2692_CR27","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1086\/520219","volume":"29","author":"AJ Simpson","year":"1999","unstructured":"Simpson AJ, Suputtamongkol Y, Smith MD, Angus BJ, Rajanuwong A, Wuthiekanun V, et al. Comparison of Imipenem and Ceftazidime as therapy for severe melioidosis. Clin Infect Dis. 1999;29(2):381\u20137. https:\/\/doi.org\/10.1086\/520219","journal-title":"Clin Infect Dis"},{"issue":"3","key":"2692_CR28","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1093\/jac\/37.3.611","volume":"37","author":"MD Smith","year":"1996","unstructured":"Smith MD, Wuthiekanun V, Walsh AL, White NJ. In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of burkholderia Pseudomallei. J Antimicrob Chemother. 1996;37(3):611\u20135. https:\/\/doi.org\/10.1093\/jac\/37.3.611","journal-title":"J Antimicrob Chemother"},{"issue":"12","key":"2692_CR29","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.3201\/eid1812.120638","volume":"18","author":"R Lipsitz","year":"2012","unstructured":"Lipsitz R, Garges S, Aurigemma R, Baccam P, Blaney DD, Cheng AC, et al. Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010. Emerg Infect Dis. 2012;18(12):e2. https:\/\/doi.org\/10.3201\/eid1812.120638","journal-title":"Emerg Infect Dis"},{"issue":"3","key":"2692_CR30","doi-asserted-by":"publisher","first-page":"e0003586","DOI":"10.1371\/journal.pntd.0003586","volume":"9","author":"MC Pitman","year":"2015","unstructured":"Pitman MC, Luck T, Marshall CS, Anstey NM, Ward L, Currie BJ. Intravenous therapy duration and outcomes in melioidosis: a new treatment paradigm. PLoS Negl Trop Dis. 2015;9(3):e0003586. https:\/\/doi.org\/10.1371\/journal.pntd.0003586","journal-title":"PLoS Negl Trop Dis"}],"container-title":["Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s15010-025-02692-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s15010-025-02692-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s15010-025-02692-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T18:54:36Z","timestamp":1774551276000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s15010-025-02692-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,28]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["2692"],"URL":"https:\/\/doi.org\/10.1007\/s15010-025-02692-9","relation":{},"ISSN":["0300-8126","1439-0973"],"issn-type":[{"value":"0300-8126","type":"print"},{"value":"1439-0973","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,28]]},"assertion":[{"value":"18 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Patients signed informed consent regarding publishing their data and photographs.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patients\u2019 consent"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}