{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:29:20Z","timestamp":1790713760977,"version":"4.1.0"},"reference-count":85,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","award":["Medical writing and publication fees were funded by Pfizer, Egypt"],"award-info":[{"award-number":["Medical writing and publication fees were funded by Pfizer, Egypt"]}],"id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiol Ther"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1007\/s40119-022-00299-x","type":"journal-article","created":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T17:06:21Z","timestamp":1673111181000},"page":"197-213","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Detection and Diagnosis of Cardiac Amyloidosis in Egypt"],"prefix":"10.1007","volume":"12","author":[{"given":"Mohamed","family":"Abdelghany","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdy","family":"Abdelhamid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel","family":"Allam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel","family":"El Etriby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherif","family":"Hafez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5409-9745","authenticated-orcid":false,"given":"Hany","family":"Ragy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Sobhy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,7]]},"reference":[{"issue":"10","key":"299_CR1","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1161\/CIRCULATIONAHA.111.078915","volume":"126","author":"FL Ruberg","year":"2012","unstructured":"Ruberg FL, Berk JL. Transthyretin (TTR) cardiac amyloidosis. Circulation. 2012;126(10):1286\u2013300.","journal-title":"Circulation"},{"issue":"11","key":"299_CR2","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1056\/NEJMoa1805689","volume":"379","author":"MS Maurer","year":"2018","unstructured":"Maurer MS, Schwartz JH, Gundapaneni B, Elliott PM, Merlini G, Waddington-Cruz M, et al. Tafamidis treatment for patients with transthyretin amyloid cardiomyopathy. N Engl J Med. 2018;379(11):1007\u201316.","journal-title":"N Engl J Med"},{"issue":"Suppl 2","key":"299_CR3","doi-asserted-by":"publisher","first-page":"s30","DOI":"10.7861\/clinmedicine.18-2-s30","volume":"18","author":"A Martinez-Naharro","year":"2018","unstructured":"Martinez-Naharro A, Hawkins PN, Fontana M. Cardiac amyloidosis. Clin Med (Lond). 2018;18(Suppl 2):s30\u20135.","journal-title":"Clin Med (Lond)"},{"issue":"16","key":"299_CR4","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1093\/eurheartj\/ehab072","volume":"42","author":"P Garcia-Pavia","year":"2021","unstructured":"Garcia-Pavia P, Rapezzi C, Adler Y, Arad M, Basso C, Brucato A, et al. Diagnosis and treatment of cardiac amyloidosis: a position statement of the ESC Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2021;42(16):1554\u201368.","journal-title":"Eur Heart J"},{"issue":"11","key":"299_CR5","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/j.recesp.2017.05.018","volume":"70","author":"E Gonzalez-Lopez","year":"2017","unstructured":"Gonzalez-Lopez E, Lopez-Sainz A, Garcia-Pavia P. Diagnosis and treatment of transthyretin cardiac amyloidosis. Progress and hope. Rev Esp Cardiol (Engl Ed). 2017;70(11):991\u20131004.","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"issue":"1","key":"299_CR6","doi-asserted-by":"publisher","first-page":"e7","DOI":"10.1161\/CIR.0000000000000792","volume":"142","author":"MM Kittleson","year":"2020","unstructured":"Kittleson MM, Maurer MS, Ambardekar AV, Bullock-Palmer RP, Chang PP, Eisen HJ, et al. Cardiac amyloidosis: Evolving diagnosis and management: a scientific statement from the American Heart Association. Circulation. 2020;142(1):e7\u201322.","journal-title":"Circulation"},{"issue":"8","key":"299_CR7","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.3390\/biomedicines10081768","volume":"10","author":"MO Versteylen","year":"2022","unstructured":"Versteylen MO, Brons M, Teske AJ, Oerlemans M. Restrictive atrial dysfunction in cardiac amyloidosis: differences between immunoglobulin light chain and transthyretin cardiac amyloidosis patients. Biomedicines. 2022;10(8):1768\u201378.","journal-title":"Biomedicines"},{"issue":"1","key":"299_CR8","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1056\/NEJMoa2028631","volume":"385","author":"E Kastritis","year":"2021","unstructured":"Kastritis E, Palladini G, Minnema MC, Wechalekar AD, Jaccard A, Lee HC, et al. Daratumumab-based treatment for immunoglobulin light-chain amyloidosis. N Engl J Med. 2021;385(1):46\u201358.","journal-title":"N Engl J Med"},{"issue":"12 Suppl 3","key":"299_CR9","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3949\/ccjm.84.s3.02","volume":"84","author":"JP Donnelly","year":"2017","unstructured":"Donnelly JP, Hanna M. Cardiac amyloidosis: an update on diagnosis and treatment. Cleve Clin J Med. 2017;84(12 Suppl 3):12\u201326.","journal-title":"Cleve Clin J Med"},{"issue":"11","key":"299_CR10","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1016\/j.hlc.2022.08.002","volume":"31","author":"ASY See","year":"2022","unstructured":"See ASY, Ho JS-Y, Chan MY, Lim YC, Yeo T-C, Chai P, et al. Prevalence and risk factors of cardiac amyloidosis in heart failure: a systematic review and meta-analysis. Heart Lung Circ. 2022;31(11):1450\u201362.","journal-title":"Heart Lung Circ"},{"issue":"11","key":"299_CR11","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/s12471-019-1299-1","volume":"27","author":"M Oerlemans","year":"2019","unstructured":"Oerlemans M, Rutten KHG, Minnema MC, Raymakers RAP, Asselbergs FW, de Jonge N. Cardiac amyloidosis: the need for early diagnosis. Neth Heart J. 2019;27(11):525\u201336.","journal-title":"Neth Heart J"},{"issue":"14","key":"299_CR12","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1136\/heartjnl-2016-310704","volume":"103","author":"M Grogan","year":"2017","unstructured":"Grogan M, Dispenzieri A, Gertz MA. Light-chain cardiac amyloidosis: strategies to promote early diagnosis and cardiac response. Heart. 2017;103(14):1065\u201372.","journal-title":"Heart"},{"issue":"5","key":"299_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41408-018-0080-9","volume":"8","author":"MA Gertz","year":"2018","unstructured":"Gertz MA. Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2018. Blood Cancer J. 2018;8(5):1\u20138.","journal-title":"Blood Cancer J"},{"issue":"10","key":"299_CR14","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1016\/j.jhsa.2019.06.016","volume":"44","author":"JP Donnelly","year":"2019","unstructured":"Donnelly JP, Hanna M, Sperry BW, Seitz WH Jr. Carpal tunnel syndrome: a potential early, red-flag sign of amyloidosis. J Hand Surg Am. 2019;44(10):868\u201376.","journal-title":"J Hand Surg Am"},{"issue":"4","key":"299_CR15","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s00392-020-01799-3","volume":"110","author":"A Yilmaz","year":"2021","unstructured":"Yilmaz A, Bauersachs J, Bengel F, Buchel R, Kindermann I, Klingel K, et al. Diagnosis and treatment of cardiac amyloidosis: Position statement of the German Cardiac Society (DGK). Clin Res Cardiol. 2021;110(4):479\u2013506.","journal-title":"Clin Res Cardiol"},{"key":"299_CR16","volume":"28","author":"M Papathanasiou","year":"2020","unstructured":"Papathanasiou M, Carpinteiro A, Rischpler C, Hagenacker T, Rassaf T, Luedike P. Diagnosing cardiac amyloidosis in every-day practice: a practical guide for the cardiologist. Int J Cardiol Heart Vasc. 2020;28: 100519.","journal-title":"Int J Cardiol Heart Vasc"},{"issue":"9","key":"299_CR17","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1253\/circj.CJ-20-0110","volume":"84","author":"H Kitaoka","year":"2020","unstructured":"Kitaoka H, Izumi C, Izumiya Y, Inomata T, Ueda M, Kubo T, et al. JCS 2020 guideline on diagnosis and treatment of cardiac amyloidosis. Circ J. 2020;84(9):1610\u201371.","journal-title":"Circ J"},{"issue":"24","key":"299_CR18","doi-asserted-by":"publisher","first-page":"2404","DOI":"10.1161\/CIRCULATIONAHA.116.021612","volume":"133","author":"JD Gillmore","year":"2016","unstructured":"Gillmore JD, Maurer MS, Falk RH, Merlini G, Damy T, Dispenzieri A, et al. Nonbiopsy diagnosis of cardiac transthyretin amyloidosis. Circulation. 2016;133(24):2404\u201312.","journal-title":"Circulation"},{"issue":"16","key":"299_CR19","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1056\/NEJMc1917321","volume":"382","author":"S Ravichandran","year":"2020","unstructured":"Ravichandran S, Lachmann HJ, Wechalekar AD. Epidemiologic and survival trends in amyloidosis, 1987\u20132019. N Engl J Med. 2020;382(16):1567\u20138.","journal-title":"N Engl J Med"},{"issue":"6","key":"299_CR20","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.118.005407","volume":"12","author":"LG Gilstrap","year":"2019","unstructured":"Gilstrap LG, Dominici F, Wang Y, El-Sady MS, Singh A, Di Carli MF, et al. Epidemiology of cardiac amyloidosis-associated heart failure hospitalizations among Fee-for-Service Medicare beneficiaries in the United States. Circ Heart Fail. 2019;12(6): e005407.","journal-title":"Circ Heart Fail"},{"issue":"3","key":"299_CR21","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.jaccao.2022.05.011","volume":"4","author":"F Al Badarin","year":"2022","unstructured":"Al Badarin F, Al-Humood K, Bader F, Alsaid S, Sulaiman K, Alzadjali M, et al. Physician knowledge and awareness about cardiac amyloidosis in the Middle East and Gulf region. JACC CardioOncol. 2022;4(3):421\u20134.","journal-title":"JACC CardioOncol"},{"issue":"1","key":"299_CR22","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/s40246-021-00351-2","volume":"15","author":"M Abouelhoda","year":"2021","unstructured":"Abouelhoda M, Mohty D, Alayary I, Meyer BF, Arold ST, Fadel BM, et al. Established and candidate transthyretin amyloidosis variants identified in the Saudi population by data mining. Hum Genom. 2021;15(1):52.","journal-title":"Hum Genom"},{"issue":"1","key":"299_CR23","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1186\/s13023-022-02414-6","volume":"17","author":"N Kumar","year":"2022","unstructured":"Kumar N, Zhang NJ, Cherepanov D, Romanus D, Hughes M, Faller DV. Global epidemiology of amyloid light-chain amyloidosis. Orphanet J Rare Dis. 2022;17(1):278.","journal-title":"Orphanet J Rare Dis"},{"issue":"3","key":"299_CR24","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.119.006619","volume":"13","author":"F Cappelli","year":"2020","unstructured":"Cappelli F, Vignini E, Martone R, Perlini S, Mussinelli R, Sabena A, et al. Baseline ECG features and arrhythmic profile in transthyretin versus light chain cardiac amyloidosis. Circ Heart Fail. 2020;13(3): e006619.","journal-title":"Circ Heart Fail"},{"issue":"5","key":"299_CR25","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.118.007826","volume":"11","author":"OK Siddiqi","year":"2018","unstructured":"Siddiqi OK, Sanchorawala V, Ruberg FL. Echocardiography and survival in light chain cardiac amyloidosis. Circ Cardiovasc. 2018;11(5): e007826.","journal-title":"Circ Cardiovasc"},{"issue":"7","key":"299_CR26","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.3390\/biomedicines10071566","volume":"10","author":"M Rossi","year":"2022","unstructured":"Rossi M, Varr\u00e0 GG, Porcari A, Saro R, Pagura L, Lalario A, et al. Re-definition of the epidemiology of cardiac amyloidosis. Biomedicines. 2022;10(7):1566.","journal-title":"Biomedicines"},{"issue":"8","key":"299_CR27","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1038\/s41408-021-00529-w","volume":"11","author":"A Staron","year":"2021","unstructured":"Staron A, Zheng L, Doros G, Connors LH, Mendelson LM, Joshi T, et al. Marked progress in AL amyloidosis survival: a 40-year longitudinal natural history study. Blood Cancer J. 2021;11(8):139.","journal-title":"Blood Cancer J"},{"issue":"22","key":"299_CR28","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1161\/CIRCULATIONAHA.122.060852","volume":"146","author":"A Ioannou","year":"2022","unstructured":"Ioannou A, Patel RK, Razvi Y, Porcari A, Sinagra G, Venneri L, et al. Impact of earlier diagnosis in cardiac ATTR amyloidosis over the course of 20 years. Circulation. 2022;146(22):1657\u201370.","journal-title":"Circulation"},{"key":"299_CR29","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.644508","volume":"8","author":"H Sabbour","year":"2021","unstructured":"Sabbour H, Hasan KY, Al Badarin F, Alibazoglu H, Rivard AL, Romany I, et al. From clinical clues to final diagnosis: the return of detective work to clinical medicine in cardiac amyloidosis. Front Cardiovasc Med. 2021;8: 644508.","journal-title":"Front Cardiovasc Med"},{"issue":"3","key":"299_CR30","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1080\/07853890701842988","volume":"40","author":"M Tanskanen","year":"2008","unstructured":"Tanskanen M, Peuralinna T, Polvikoski T, Notkola IL, Sulkava R, Hardy J, et al. Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study. Ann Med. 2008;40(3):232\u20139.","journal-title":"Ann Med"},{"issue":"1","key":"299_CR31","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1136\/jnnp.59.1.45","volume":"59","author":"MM Reilly","year":"1995","unstructured":"Reilly MM, Staunton H, Harding AE. Familial amyloid polyneuropathy (TTR ala 60) in north west Ireland: a clinical, genetic, and epidemiological study. J Neurol Neurosurg Psychiatry. 1995;59(1):45\u20139.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"299_CR32","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1093\/eurheartj\/ehz173","volume":"43","author":"T Damy","year":"2019","unstructured":"Damy T, Kristen AV, Suhr OB, Maurer MS, Plant\u00e9-Bordeneuve V, Yu C-R, et al. Transthyretin cardiac amyloidosis in continental Western Europe: an insight through the Transthyretin Amyloidosis Outcomes Survey (THAOS). Eur Heart J. 2019;43:391\u2013400.","journal-title":"Eur Heart J"},{"issue":"3","key":"299_CR33","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1046\/j.1365-2796.2003.01173.x","volume":"254","author":"OB Suhr","year":"2003","unstructured":"Suhr OB, Svendsen IH, Andersson R, Danielsson A, Holmgren G, Ranlov PJ. Hereditary transthyretin amyloidosis from a Scandinavian perspective. J Intern Med. 2003;254(3):225\u201335.","journal-title":"J Intern Med"},{"issue":"10","key":"299_CR34","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1002\/ejhf.1285","volume":"20","author":"C Gagliardi","year":"2018","unstructured":"Gagliardi C, Perfetto F, Lorenzini M, Ferlini A, Salvi F, Milandri A, et al. Phenotypic profile of Ile68Leu transthyretin amyloidosis: an underdiagnosed cause of heart failure. Eur J Heart Fail. 2018;20(10):1417\u201325.","journal-title":"Eur J Heart Fail"},{"issue":"1","key":"299_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13023-018-0801-y","volume":"13","author":"A Gonz\u00e1lez-Duarte","year":"2018","unstructured":"Gonz\u00e1lez-Duarte A, C\u00e1rdenas-Soto K, Ba\u00f1uelos CE, Fueyo O, Dominguez C, Torres B, et al. Amyloidosis due to TTR mutations in Mexico with 4 distinct genotypes in the index cases. Orphanet J Rare Dis. 2018;13(1):1\u20137.","journal-title":"Orphanet J Rare Dis"},{"issue":"2","key":"299_CR36","doi-asserted-by":"publisher","first-page":"140","DOI":"10.3109\/13506129.2014.892871","volume":"21","author":"J Yin","year":"2014","unstructured":"Yin J, Xia X, Shi Y, Lu Y, Zhao C, Huang Z, et al. Chinese familial transthyretin amyloidosis with vitreous involvement is associated with the transthyretin mutation Gly83Arg: a case report and literature review. Amyloid. 2014;21(2):140\u20132.","journal-title":"Amyloid"},{"issue":"1","key":"299_CR37","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1080\/13506129.2018.1556156","volume":"26","author":"I Concei\u00e7\u00e3o","year":"2019","unstructured":"Concei\u00e7\u00e3o I, Damy T, Romero M, Gal\u00e1n L, Attarian S, Luigetti M, et al. Early diagnosis of ATTR amyloidosis through targeted follow-up of identified carriers of TTR gene mutations. Amyloid. 2019;26(1):3\u20139.","journal-title":"Amyloid"},{"issue":"10","key":"299_CR38","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1007\/s12325-015-0250-0","volume":"32","author":"I Lousada","year":"2015","unstructured":"Lousada I, Comenzo RL, Landau H, Guthrie S, Merlini G. Light chain amyloidosis: patient experience survey from the amyloidosis research consortium. Adv Ther. 2015;32(10):920\u20138.","journal-title":"Adv Ther"},{"issue":"12","key":"299_CR39","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1016\/j.amjmed.2015.05.039","volume":"128","author":"MS Maurer","year":"2015","unstructured":"Maurer MS. Noninvasive identification of ATTRwt cardiac amyloid: the re-emergence of nuclear cardiology. Am J Med. 2015;128(12):1275\u201380.","journal-title":"Am J Med"},{"issue":"5","key":"299_CR40","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/s41408-021-00483-7","volume":"11","author":"M Hasib Sidiqi","year":"2021","unstructured":"Hasib Sidiqi M, Gertz MA. Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2021. Blood Cancer J. 2021;11(5):90.","journal-title":"Blood Cancer J"},{"issue":"13","key":"299_CR41","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1161\/CIRCULATIONAHA.108.843334","volume":"120","author":"C Rapezzi","year":"2009","unstructured":"Rapezzi C, Merlini G, Quarta CC, Riva L, Longhi S, Leone O, et al. Systemic cardiac amyloidoses: disease profiles and clinical courses of the 3 main types. Circulation. 2009;120(13):1203\u201312.","journal-title":"Circulation"},{"issue":"4","key":"299_CR42","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.amjcard.2004.10.028","volume":"95","author":"B Murtagh","year":"2005","unstructured":"Murtagh B, Hammill SC, Gertz MA, Kyle RA, Tajik AJ, Grogan M. Electrocardiographic findings in primary systemic amyloidosis and biopsy-proven cardiac involvement. Am J Cardiol. 2005;95(4):535\u20137.","journal-title":"Am J Cardiol"},{"issue":"10","key":"299_CR43","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1016\/j.acvd.2013.06.051","volume":"106","author":"D Mohty","year":"2013","unstructured":"Mohty D, Damy T, Cosnay P, Echahidi N, Casset-Senon D, Virot P, et al. Cardiac amyloidosis: updates in diagnosis and management. Arch Cardiovasc Dis. 2013;106(10):528\u201340.","journal-title":"Arch Cardiovasc Dis"},{"key":"299_CR44","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.jaccao.2022.08.007","volume":"4","author":"A Cipriani","year":"2022","unstructured":"Cipriani A, Michieli LD, Porcari A, Licchelli L, Sinigiani G, Tini G, et al. Low QRS voltages in cardiac amyloidosis: clinical correlates and prognostic value. JACC CardioOncol. 2022;4:458\u201370.","journal-title":"JACC CardioOncol"},{"issue":"6","key":"299_CR45","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1016\/j.jcmg.2019.07.015","volume":"13","author":"S Dorbala","year":"2020","unstructured":"Dorbala S, Cuddy S, Falk RH. How to image cardiac amyloidosis: a practical approach. JACC Cardiovasc Imaging. 2020;13(6):1368\u201383.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"1","key":"299_CR46","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1093\/ehjci\/jes227","volume":"14","author":"F Miller Jr","year":"2013","unstructured":"Miller F Jr, Bellavia D. Comparison of right ventricular longitudinal strain imaging, tricuspid annular plane systolic excursion, and cardiac biomarkers for early diagnosis of cardiac involvement and risk stratification in primary systematic (AL) amyloidosis: a 5-year cohort study: reply. Eur Heart J Cardiovasc Imaging. 2013;14(1):91\u20132.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"18","key":"299_CR47","doi-asserted-by":"publisher","first-page":"2490","DOI":"10.1161\/CIRCULATIONAHA.108.785014","volume":"119","author":"D Feng","year":"2009","unstructured":"Feng D, Syed IS, Martinez M, Oh JK, Jaffe AS, Grogan M, et al. Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis. Circulation. 2009;119(18):2490\u20137.","journal-title":"Circulation"},{"issue":"2","key":"299_CR48","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s12350-013-9800-5","volume":"21","author":"WA Aljaroudi","year":"2014","unstructured":"Aljaroudi WA, Desai MY, Tang WH, Phelan D, Cerqueira MD, Jaber WA. Role of imaging in the diagnosis and management of patients with cardiac amyloidosis: state of the art review and focus on emerging nuclear techniques. J Nucl Cardiol. 2014;21(2):271\u201383.","journal-title":"J Nucl Cardiol"},{"issue":"4","key":"299_CR49","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.echo.2013.12.010","volume":"27","author":"R Suresh","year":"2014","unstructured":"Suresh R, Grogan M, Maleszewski JJ, Pellikka PA, Hanna M, Dispenzieri A, et al. Advanced cardiac amyloidosis associated with normal interventricular septal thickness: an uncommon presentation of infiltrative cardiomyopathy. J Am Soc Echocardiogr. 2014;27(4):440\u20137.","journal-title":"J Am Soc Echocardiogr"},{"issue":"1","key":"299_CR50","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/S0002-9149(97)00293-2","volume":"80","author":"MA Gertz","year":"1997","unstructured":"Gertz MA, Grogan M, Kyle RA, Tajik AJ. Endomyocardial biopsy-proven light chain amyloidosis (AL) without echocardiographic features of infiltrative cardiomyopathy. Am J Cardiol. 1997;80(1):93\u20135.","journal-title":"Am J Cardiol"},{"issue":"3","key":"299_CR51","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/j.ijcard.2014.07.100","volume":"176","author":"T Nakahashi","year":"2014","unstructured":"Nakahashi T, Arita T, Yamaji K, Inoue K, Yokota T, Hoshii Y, et al. Impact of clinical and echocardiographic characteristics on occurrence of cardiac events in cardiac amyloidosis as proven by endomyocardial biopsy. Int J Cardiol. 2014;176(3):753\u20139.","journal-title":"Int J Cardiol"},{"issue":"17","key":"299_CR52","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.1177\/2047487319877708","volume":"27","author":"G Vergaro","year":"2020","unstructured":"Vergaro G, Aimo A, Barison A, Genovesi D, Buda G, Passino C, et al. Keys to early diagnosis of cardiac amyloidosis: red flags from clinical, laboratory and imaging findings. Eur J Prev Cardiol. 2020;27(17):1806\u201315.","journal-title":"Eur J Prev Cardiol"},{"issue":"1","key":"299_CR53","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1186\/s12872-016-0311-6","volume":"16","author":"L Zhao","year":"2016","unstructured":"Zhao L, Tian Z, Fang Q. Diagnostic accuracy of cardiovascular magnetic resonance for patients with suspected cardiac amyloidosis: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2016;16(1):129.","journal-title":"BMC Cardiovasc Disord"},{"issue":"10","key":"299_CR54","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1016\/j.jacc.2007.10.049","volume":"51","author":"H Vogelsberg","year":"2008","unstructured":"Vogelsberg H, Mahrholdt H, Deluigi CC, Yilmaz A, Kispert EM, Greulich S, et al. Cardiovascular magnetic resonance in clinically suspected cardiac amyloidosis: noninvasive imaging compared to endomyocardial biopsy. J Am Coll Cardiol. 2008;51(10):1022\u201330.","journal-title":"J Am Coll Cardiol"},{"issue":"8","key":"299_CR55","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1093\/ehjci\/jeaa063","volume":"21","author":"R Jurcut","year":"2020","unstructured":"Jurcut R, Onciul S, Adam R, Stan C, Coriu D, Rapezzi C, et al. Multimodality imaging in cardiac amyloidosis: a primer for cardiologists. Eur Heart J Cardiovasc Imaging. 2020;21(8):833\u201344.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"25","key":"299_CR56","doi-asserted-by":"publisher","first-page":"2919","DOI":"10.1016\/j.jacc.2018.03.536","volume":"71","author":"T Kotecha","year":"2018","unstructured":"Kotecha T, Martinez-Naharro A, Treibel TA, Francis R, Nordin S, Abdel-Gadir A, et al. Myocardial edema and prognosis in amyloidosis. J Am Coll Cardiol. 2018;71(25):2919\u201331.","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"299_CR57","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.jcmg.2009.09.023","volume":"3","author":"IS Syed","year":"2010","unstructured":"Syed IS, Glockner JF, Feng D, Araoz PA, Martinez MW, Edwards WD, et al. Role of cardiac magnetic resonance imaging in the detection of cardiac amyloidosis. JACC Cardiovasc Imaging. 2010;3(2):155\u201364.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"3","key":"299_CR58","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1080\/21678707.2021.1898371","volume":"9","author":"T Rezk","year":"2021","unstructured":"Rezk T, Fontana M, Gillmore JD. A review of the criteria for non-invasive diagnosis of cardiac transthyretin amyloidosis. Expert Opin Orphan Drugs. 2021;9(3):87\u201394.","journal-title":"Expert Opin Orphan Drugs"},{"issue":"7","key":"299_CR59","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1097\/RLI.0000000000000556","volume":"54","author":"J Hao","year":"2019","unstructured":"Hao J, Bourrinet P, Desch\u00e9 P. Assessment of pharmacokinetic, pharmacodynamic profile, and tolerance of gadopiclenol, a new high relaxivity GBCA, in healthy subjects and patients with brain lesions (phase I\/IIa study). Investig Radiol. 2019;54(7):396\u2013402.","journal-title":"Investig Radiol"},{"issue":"2","key":"299_CR60","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s10741-014-9470-7","volume":"20","author":"M Fontana","year":"2015","unstructured":"Fontana M, Chung R, Hawkins PN, Moon JC. Cardiovascular magnetic resonance for amyloidosis. Heart Fail Rev. 2015;20(2):133\u201344.","journal-title":"Heart Fail Rev"},{"issue":"9","key":"299_CR61","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1016\/j.jcmg.2012.04.006","volume":"5","author":"F-P Mongeon","year":"2012","unstructured":"Mongeon F-P, Jerosch-Herold M, Coelho-Filho OR, Blankstein R, Falk RH, Kwong RY. Quantification of extracellular matrix expansion by CMR in infiltrative heart disease. JACC Cardiovasc Imaging. 2012;5(9):897\u2013907.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"Suppl 3","key":"299_CR62","volume":"142","author":"F Al Badarin","year":"2020","unstructured":"Al Badarin F, Al Ali J, Bader F, Shehab AM, Al Said S, Sulaiman K, et al. Knowledge of clinical presentation and diagnostic pathways for cardiac amyloidosis among physicians in the Middle East-Gulf region: on behalf of the Gulf Cardiac Amyloidosis Working Group. Circulation. 2020;142(Suppl 3): A16240-A.","journal-title":"Circulation"},{"issue":"3","key":"299_CR63","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1373\/clinchem.2008.117143","volume":"55","author":"G Palladini","year":"2009","unstructured":"Palladini G, Russo P, Bosoni T, Verga L, Sarais G, Lavatelli F, et al. Identification of amyloidogenic light chains requires the combination of serum-free light chain assay with immunofixation of serum and urine. Clin Chem. 2009;55(3):499\u2013504.","journal-title":"Clin Chem"},{"issue":"10","key":"299_CR64","doi-asserted-by":"publisher","first-page":"2358","DOI":"10.1007\/s00330-006-0249-7","volume":"16","author":"F Van Geluwe","year":"2006","unstructured":"Van Geluwe F, Dymarkowski S, Crevits I, De Wever W, Bogaert J. Amyloidosis of the heart and respiratory system. Eur Radiol. 2006;16(10):2358\u201365.","journal-title":"Eur Radiol"},{"key":"299_CR65","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2020.100720","volume":"45","author":"C Varga","year":"2021","unstructured":"Varga C, Dorbala S, Lousada I, Polydefkis MJ, Wechalekar A, Maurer MS, et al. The diagnostic challenges of cardiac amyloidosis: a practical approach to the two main types. Blood Rev. 2021;45: 100720.","journal-title":"Blood Rev"},{"key":"299_CR66","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-022-10247-5","author":"A Porcari","year":"2022","unstructured":"Porcari A, Baggio C, Fabris E, Merlo M, Bussani R, Perkan A, et al. Endomyocardial biopsy in the clinical context: current indications and challenging scenarios. Heart Fail Rev. 2022. https:\/\/doi.org\/10.1007\/s10741-022-10247-5.","journal-title":"Heart Fail Rev"},{"key":"299_CR67","unstructured":"Mayo Foundation for Medical Education and Research M. Amyloidosis 2021. https:\/\/www.mayoclinic.org\/diseases-conditions\/amyloidosis\/diagnosis-treatment\/drc-20353183."},{"issue":"5","key":"299_CR68","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1038\/s41431-019-0337-1","volume":"27","author":"CL Pueyo","year":"2019","unstructured":"Pueyo CL, Arregui M\u00c1A, Gutierrez AG, Juana EB, Guill\u00e9n SM. Estimating the prevalence of allelic variants in the transthyretin gene by analysing large-scale sequencing data. Eur J Hum Genet. 2019;27(5):783\u201391.","journal-title":"Eur J Hum Genet"},{"issue":"7","key":"299_CR69","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1007\/s11606-007-0207-3","volume":"22","author":"B Garibaldi","year":"2007","unstructured":"Garibaldi B, Zaas D. An unusual case of cardiac amyloidosis. J Gen Intern Med. 2007;22(7):1047\u201352.","journal-title":"J Gen Intern Med"},{"issue":"14","key":"299_CR70","doi-asserted-by":"publisher","first-page":"1924","DOI":"10.1200\/JCO.2010.32.2271","volume":"29","author":"G Merlini","year":"2011","unstructured":"Merlini G, Seldin DC, Gertz MA. Amyloidosis: pathogenesis and new therapeutic options. J Clin Oncol. 2011;29(14):1924.","journal-title":"J Clin Oncol"},{"issue":"2","key":"299_CR71","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1161\/CIRCIMAGING.112.000132","volume":"6","author":"S Bokhari","year":"2013","unstructured":"Bokhari S, Casta\u00f1o A, Pozniakoff T, Deslisle S, Latif F, Maurer MS. 99mTc-pyrophosphate scintigraphy for differentiating light-chain cardiac amyloidosis from the transthyretin-related familial and senile cardiac amyloidoses. Circ Cardiovasc. 2013;6(2):195\u2013201.","journal-title":"Circ Cardiovasc"},{"issue":"14","key":"299_CR72","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1161\/CIRCULATIONAHA.116.024438","volume":"135","author":"MS Maurer","year":"2017","unstructured":"Maurer MS, Elliott P, Comenzo R, Semigran M, Rapezzi C. Addressing common questions encountered in the diagnosis and management of cardiac amyloidosis. Circulation. 2017;135(14):1357\u201377.","journal-title":"Circulation"},{"issue":"10","key":"299_CR73","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1001\/jama.2017.9236","volume":"318","author":"HI Geller","year":"2017","unstructured":"Geller HI, Singh A, Alexander KM, Mirto TM, Falk RH. Association between ruptured distal biceps tendon and wild-type transthyretin cardiac amyloidosis. JAMA. 2017;318(10):962\u20133.","journal-title":"JAMA"},{"issue":"17","key":"299_CR74","doi-asserted-by":"publisher","first-page":"2040","DOI":"10.1016\/j.jacc.2018.07.092","volume":"72","author":"BW Sperry","year":"2018","unstructured":"Sperry BW, Reyes BA, Ikram A, Donnelly JP, Phelan D, Jaber WA, et al. Tenosynovial and cardiac amyloidosis in patients undergoing carpal tunnel release. J Am Coll Cardiol. 2018;72(17):2040\u201350.","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"299_CR75","volume":"13","author":"RP Boyle","year":"2021","unstructured":"Boyle RP, Sharan J, Schwartz G. Carpal tunnel syndrome in transthyretin cardiac amyloidosis: Implications and protocol for diagnosis and treatment. Cureus. 2021;13(4): e14546.","journal-title":"Cureus"},{"issue":"9","key":"299_CR76","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1200\/JCO.2011.38.5724","volume":"30","author":"S Kumar","year":"2012","unstructured":"Kumar S, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK, Colby C, et al. Revised prognostic staging system for light chain amyloidosis incorporating cardiac biomarkers and serum free light chain measurements. J Clin Oncol. 2012;30(9):989\u201395.","journal-title":"J Clin Oncol"},{"issue":"30","key":"299_CR77","doi-asserted-by":"publisher","first-page":"2799","DOI":"10.1093\/eurheartj\/ehx589","volume":"39","author":"JD Gillmore","year":"2018","unstructured":"Gillmore JD, Damy T, Fontana M, Hutchinson M, Lachmann HJ, Martinez-Naharro A, et al. A new staging system for cardiac transthyretin amyloidosis. Eur Heart J. 2018;39(30):2799\u2013806.","journal-title":"Eur Heart J"},{"issue":"10","key":"299_CR78","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1016\/j.jacc.2016.06.033","volume":"68","author":"M Grogan","year":"2016","unstructured":"Grogan M, Scott CG, Kyle RA, Zeldenrust SR, Gertz MA, Lin G, et al. Natural history of wild-type transthyretin cardiac amyloidosis and risk stratification using a novel staging system. J Am Coll Cardiol. 2016;68(10):1014\u201320.","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"299_CR79","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.tcm.2017.07.004","volume":"28","author":"OK Siddiqi","year":"2018","unstructured":"Siddiqi OK, Ruberg FL. Cardiac amyloidosis: an update on pathophysiology, diagnosis, and treatment. Trends Cardiovasc Med. 2018;28(1):10\u201321.","journal-title":"Trends Cardiovasc Med"},{"key":"299_CR80","doi-asserted-by":"publisher","first-page":"561","DOI":"10.36660\/abc.20210718","volume":"117","author":"MV Sim\u00f5es","year":"2021","unstructured":"Sim\u00f5es MV, Fernandes F, Marcondes-Braga FG, Scheinberg P, Correia EDB, Rohde LEP, et al. Position statement on diagnosis and treatment of cardiac amyloidosis\u20142021. Arq Bras Cardiol. 2021;117:561\u201398.","journal-title":"Arq Bras Cardiol"},{"issue":"2","key":"299_CR81","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s10741-014-9464-5","volume":"20","author":"M Grogan","year":"2015","unstructured":"Grogan M, Dispenzieri A. Natural history and therapy of AL cardiac amyloidosis. Heart Fail Rev. 2015;20(2):155\u201362.","journal-title":"Heart Fail Rev"},{"issue":"8","key":"299_CR82","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.cardfail.2018.07.001","volume":"24","author":"J Rubin","year":"2018","unstructured":"Rubin J, Steidley DE, Carlsson M, Ong M-L, Maurer MS. Myocardial contraction fraction by M-mode echocardiography is superior to ejection fraction in predicting mortality in transthyretin amyloidosis. J Cardiac Fail. 2018;24(8):504\u201311.","journal-title":"J Cardiac Fail"},{"issue":"8","key":"299_CR83","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1001\/jamacardio.2016.2839","volume":"1","author":"A Castano","year":"2016","unstructured":"Castano A, Haq M, Narotsky DL, Goldsmith J, Weinberg RL, Morgenstern R, et al. Multicenter study of planar technetium 99m pyrophosphate cardiac imaging: predicting survival for patients with ATTR cardiac amyloidosis. JAMA Cardiol. 2016;1(8):880\u20139.","journal-title":"JAMA Cardiol"},{"issue":"16","key":"299_CR84","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1161\/CIRCULATIONAHA.115.016567","volume":"132","author":"M Fontana","year":"2015","unstructured":"Fontana M, Pica S, Reant P, Abdel-Gadir A, Treibel TA, Banypersad SM, et al. Prognostic value of late gadolinium enhancement cardiovascular magnetic resonance in cardiac amyloidosis. Circulation. 2015;132(16):1570\u20139.","journal-title":"Circulation"},{"issue":"10","key":"299_CR85","doi-asserted-by":"publisher","first-page":"S53","DOI":"10.1016\/j.cardfail.2020.09.155","volume":"26","author":"E Raichlin","year":"2020","unstructured":"Raichlin E, Sagalovich M. Survey conducted at an academic medical center revealed knowledge gaps of transthyretin amyloidosis cardiomyopathy predominantly in primary care providers. J Cardiac Fail. 2020;26(10):S53.","journal-title":"J Cardiac Fail"}],"container-title":["Cardiology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40119-022-00299-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40119-022-00299-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40119-022-00299-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T02:11:04Z","timestamp":1678068664000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40119-022-00299-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,7]]},"references-count":85,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["299"],"URL":"https:\/\/doi.org\/10.1007\/s40119-022-00299-x","relation":{},"ISSN":["2193-8261","2193-6544"],"issn-type":[{"value":"2193-8261","type":"print"},{"value":"2193-6544","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,7]]},"assertion":[{"value":"18 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}