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The sponsor also funded the journal\u2019s Rapid Service.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"All authors made a significant contribution to the work reported in study conception, design, execution, acquisition of data, and analysis and interpretation. All contributed to the article\u2019s drafting, revision, or critical review; all gave final approval of the version to be published; all agreed on the journal to which the article was submitted; and all agreed to be held accountable for all aspects of the work.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author Contributions"}},{"value":"Mar\u00eda Branas-Pampill\u00f3n, Rosana Cabello-Moruno, Paola D\u00edaz-Ab\u00f3s, Victoria S\u00e1nchez-Men\u00e9ndez, and Jorge Maurino are employees of Roche Farma, Spain. Pablo Rebollo is an employee of IQVIA Spain. Juan F V\u00e1zquez-Costa, Julita Medina-Cantillo, M\u00f3nica Povedano, Inmaculada Pitarch-Castellano, Mercedes L\u00f3pez-Lobato, Joaqu\u00edn A Fern\u00e1ndez-Ramos, Miguel Lafuente-Hidalgo, Ricard Rojas-Garc\u00eda, Jos\u00e9 M Caballero-Caballero, Ignacio M\u00e1laga, Jes\u00fas Eir\u00eds-Pu\u00f1al, Menc\u00eda De Lemus, Mar\u00eda G Cattinari, and Marco Madruga-Garrido declare no conflict of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interests"}},{"value":"The SMA-TOOL study was conducted in accordance with the Good Clinical Practice Guidelines of the International Conference on Harmonisation and with the ethical principles of the Declaration of Helsinki and was approved by the investigational review board of the Hospital Universitari de Bellvitge (Barcelona, Spain; reference code: PR264\/20). Written informed consent was obtained from all subjects.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethics Guidelines"}},{"value":"Qualified researchers may request access to individual patient-level data through the corresponding author. The datasets generated during the analysis of the study are available from the corresponding author on reasonable request.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data Availability"}}]}}