{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:15:16Z","timestamp":1789668916270,"version":"4.0.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,2,15]],"date-time":"2020-02-15T00:00:00Z","timestamp":1581724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2020,2,15]],"date-time":"2020-02-15T00:00:00Z","timestamp":1581724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Ther"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s40121-020-00285-7","type":"journal-article","created":{"date-parts":[[2020,2,15]],"date-time":"2020-02-15T11:03:12Z","timestamp":1581764592000},"page":"175-183","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Impact of Obesity in Patients with Candida Bloodstream Infections: A Retrospective Cohort Study"],"prefix":"10.1007","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8411-3111","authenticated-orcid":false,"given":"Katie E.","family":"Barber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie L.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily A.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayla R.","family":"Stover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,15]]},"reference":[{"issue":"11","key":"285_CR1","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1017\/ice.2016.174","volume":"37","author":"LM Weiner","year":"2016","unstructured":"Weiner LM, Webb AK, Limbago B, et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011\u20132014. Infect Control Hosp Epidemiol. 2016;37(11):1288\u2013301.","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"13","key":"285_CR2","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1056\/NEJMoa1306801","volume":"370","author":"S Magill","year":"2014","unstructured":"Magill S, Edwards J. Multistate point-prevalence survey of health care\u2013associated infections. New Engl J Med. 2014;370(13):1198\u2013208.","journal-title":"New Engl J Med"},{"key":"285_CR3","doi-asserted-by":"crossref","unstructured":"Wisplinghoff H, Ebbers J, Geurtz L, et al. Nosocomial bloodstream infections due to Candida spp. in the USA: species distribution, clinical features and antifungal susceptibilities. Int J Antimicrob Agents 2014;43(1):78\u201381.","DOI":"10.1016\/j.ijantimicag.2013.09.005"},{"issue":"9","key":"285_CR4","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1086\/378745","volume":"37","author":"O Gudlaugsson","year":"2003","unstructured":"Gudlaugsson O, Gillespie S. Attributable mortality of nosocomial Candidemia, revisited. Clin Infect Dis. 2003;37(9):1172\u20137.","journal-title":"Clin Infect Dis"},{"issue":"5","key":"285_CR5","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1086\/590566","volume":"47","author":"BH Segal","year":"2008","unstructured":"Segal BH, Herbrecht R, Stevens DA, et al. Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: mycoses study group and European organization for research and treatment of cancer consensus criteria. Clin Infect Dis. 2008;47(5):674\u201383.","journal-title":"Clin Infect Dis"},{"issue":"5","key":"285_CR6","doi-asserted-by":"publisher","first-page":"w822","DOI":"10.1377\/hlthaff.28.5.w822","volume":"28","author":"EA Finkelstein","year":"2009","unstructured":"Finkelstein EA, Trogdon JG, Cohen JW, et al. Annual medical spending attributable to obesity: payer- and service-specific estimates. Health Aff. 2009;28(5):w822\u201331.","journal-title":"Health Aff"},{"key":"285_CR7","unstructured":"Hales\u00a0CM, Carroll MD, Fryar CD, Ogden CL. Prevalence of obesity among adults and youth: United States, 2015\u20132016. Centers for Disease Control and Prevention National Center for Health Statistics Data Brief 2017;288."},{"key":"285_CR8","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1093\/cid\/civ933","volume":"62","author":"PG Pappas","year":"2016","unstructured":"Pappas PG, Kauffman CA, Andes DR, et al. Clinical practice guideline for the management of Candidiasis: 2016 update by the Infectious Diseases Society of America. Clin Infect Dis. 2016;62:e1\u201350.","journal-title":"Clin Infect Dis"},{"issue":"11","key":"285_CR9","doi-asserted-by":"publisher","first-page":"6550","DOI":"10.1128\/AAC.01088-16","volume":"60","author":"AS Alobaid","year":"2016","unstructured":"Alobaid AS, Wallis SC, Jarrett P, et al. Effect of obesity on the population pharmacokinetics of fluconazole in critically ill patients. Antimicrob Agents Chemother. 2016;60(11):6550\u20137.","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"285_CR10","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/s13054-018-2019-8","volume":"22","author":"E Maseda","year":"2018","unstructured":"Maseda E, Grau S, Luque S, et al. Population pharmacokinetics\/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients. Crit Care. 2018;22(1):94.","journal-title":"Crit Care"},{"key":"285_CR11","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1093\/jac\/dky554","volume":"74","author":"RE Wasmann","year":"2019","unstructured":"Wasmann RE, Smit C, Ter Heine R, et al. Pharmacokinetics and probability of target attainment for micafungin in normal-weight and morbidly obese adults. J Antimicrob Chemother. 2019;74:978\u201385.","journal-title":"J Antimicrob Chemother"},{"key":"285_CR12","unstructured":"Centers for Disease Control and Prevention. Defining adult overweight and obesity. Last reviewed April 11, 2017. https:\/\/www.cdc.gov\/obesity\/adult\/defining.html. Accessed 29 May 2019"},{"issue":"12","key":"285_CR13","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1099\/jmm.0.000383","volume":"65","author":"D Cretella","year":"2016","unstructured":"Cretella D, Barber KE, King ST, Stover KR. Comparison of susceptibility patterns using commercially available susceptibility testing methods performed on prevent Candida spp. J Med Microbiol. 2016;65(12):1445\u201351.","journal-title":"J Med Microbiol"},{"key":"285_CR14","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1007\/s15010-013-0455-6","volume":"41","author":"AM Tortorano","year":"2013","unstructured":"Tortorano AM, Prigitano A, Lazzarini C, et al. A 1-year prospective survey of candidemia in Italy and changing epidemiology over one decade. Infection. 2013;41:655\u201362.","journal-title":"Infection"},{"key":"285_CR15","doi-asserted-by":"publisher","first-page":"e101510","DOI":"10.1371\/journal.pone.0101510","volume":"9","author":"MA Pfaller","year":"2014","unstructured":"Pfaller MA, Andes DR, Diekema DJ, et al. Epidemiology and outcomes of invasive candidiasis due to non-albicans\u00a0species of\u00a0Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008. PLoS One. 2014;9:e101510.","journal-title":"PLoS One"},{"key":"285_CR16","doi-asserted-by":"crossref","unstructured":"Tedeschi S, Tumietto F, Giannella M, et al. Emilia Romagna Candida Network. Epidemiology and outcome of candidemia in internal medicine wards: a regional study in Italy. Eur J Intern Med 2016;34:39\u201344.","DOI":"10.1016\/j.ejim.2016.08.020"},{"key":"285_CR17","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1016\/j.ajic.2017.02.022","volume":"45","author":"E Tukenmez Tigen","year":"2017","unstructured":"Tukenmez Tigen E, Bilgin H, Perk Gurun H, et al. Risk factors, characteristics, and outcomes of candidemia in an adult intensive care unit in Turkey. Am J Infect Cont. 2017;45:e61\u20133.","journal-title":"Am J Infect Cont"},{"key":"285_CR18","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1086\/496922","volume":"41","author":"TE Zaoutis","year":"2005","unstructured":"Zaoutis TE, Argon J, Chu J, Berlin JA, Walsh TJ, Feudtner C. The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: a propensity analysis. Clin Infect Dis. 2005;41:1232\u20139.","journal-title":"Clin Infect Dis"},{"issue":"3","key":"285_CR19","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1097\/01.CCM.0000202208.37364.7D","volume":"34","author":"C Le\u00f3n","year":"2006","unstructured":"Le\u00f3n C, Ruiz-Santana S, Saavedra P, et al. A bedside scoring system (\u201cCandida score\u201d for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization. Crit Care Med. 2006;34(3):730\u20137.","journal-title":"Crit Care Med"},{"key":"285_CR20","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1093\/cid\/cis021","volume":"54","author":"DR Andes","year":"2012","unstructured":"Andes DR, Safdar N, Baddley JW, et al. Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials. Clin Infect Dis. 2012;54:1110\u201322.","journal-title":"Clin Infect Dis"},{"key":"285_CR21","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1007\/s10096-016-2835-1","volume":"36","author":"A Atamna","year":"2017","unstructured":"Atamna A, Elis A, Gilady E, Gitter-Azulay L, Bishara J. How obesity impacts outcomes of infectious diseases. Eur J Clin Microbiol Infect Dis. 2017;36:585\u201391.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"285_CR22","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1016\/j.jiac.2016.07.006","volume":"22","author":"BD Lizza","year":"2016","unstructured":"Lizza BD, Rhodes NJ, Esterly JS, Toy C, Lopez J, Scheetz MH. Impact of body mass index on clinical outcomes in patients with gram-negative bacteria bloodstream infections. J Infect Chemother. 2016;22:671\u20136.","journal-title":"J Infect Chemother"},{"issue":"4","key":"285_CR23","doi-asserted-by":"publisher","first-page":"e0154599","DOI":"10.1371\/journal.pone.0154599","volume":"11","author":"AT Nguyen","year":"2016","unstructured":"Nguyen AT, Tsai C, Hwang L, Lai D, Markham C, Patel B. Obesity and mortality, length of stay and hospital cost among patients with sepsis: a nationwide inpatient retrospective cohort study. PLoS One. 2016;11(4):e0154599.","journal-title":"PLoS One"}],"container-title":["Infectious Diseases and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-020-00285-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40121-020-00285-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-020-00285-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T06:27:38Z","timestamp":1715668058000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40121-020-00285-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,15]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["285"],"URL":"https:\/\/doi.org\/10.1007\/s40121-020-00285-7","relation":{},"ISSN":["2193-8229","2193-6382"],"issn-type":[{"value":"2193-8229","type":"print"},{"value":"2193-6382","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,15]]},"assertion":[{"value":"19 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 February 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}