{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:51:13Z","timestamp":1740167473098,"version":"3.37.3"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Ther"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s40121-020-00297-3","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T13:04:07Z","timestamp":1593522247000},"page":"609-623","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Baseline Characteristics and Outcomes Among Patients with Complicated Skin and Soft Tissue Infections Admitted to the Intensive Care Unit: Analysis of the Phase 3 COVERS Randomized Trial of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam"],"prefix":"10.1007","volume":"9","author":[{"given":"Miguel","family":"S\u00e1nchez-Garc\u00eda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Hammond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Li","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal","family":"Kantecki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wajeeha","family":"Ansari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Dryden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,6,30]]},"reference":[{"issue":"2","key":"297_CR1","doi-asserted-by":"publisher","first-page":"e10","DOI":"10.1093\/cid\/ciu296","volume":"59","author":"DL Stevens","year":"2014","unstructured":"Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59(2):e10\u2013e52.","journal-title":"Clin Infect Dis"},{"issue":"12","key":"297_CR2","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1186\/2047-783X-15-12-554","volume":"15","author":"C Eckmann","year":"2010","unstructured":"Eckmann C, Dryden M. Treatment of complicated skin and soft-tissue infections caused by resistant bacteria: value of linezolid, tigecycline, daptomycin and vancomycin. Eur J Med Res. 2010;15(12):554\u201363.","journal-title":"Eur J Med Res"},{"issue":"Suppl 2","key":"297_CR3","first-page":"ii37","volume":"53","author":"MJ DiNubile","year":"2004","unstructured":"DiNubile MJ, Lipsky BA. Complicated infections of skin and skin structures: when the infection is more than skin deep. J Antimicrob Chemother. 2004;53(Suppl 2):ii37\u201350.","journal-title":"J Antimicrob Chemother."},{"issue":"21","key":"297_CR4","doi-asserted-by":"publisher","first-page":"2323","DOI":"10.1001\/jama.2009.1754","volume":"302","author":"J-L Vincent","year":"2009","unstructured":"Vincent J-L, Rello J, Marshall J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA. 2009;302(21):2323\u20139.","journal-title":"JAMA"},{"issue":"12","key":"297_CR5","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1007\/s00134-016-4576-0","volume":"42","author":"JP Burnham","year":"2016","unstructured":"Burnham JP, Kirby JP, Kollef MH. Diagnosis and management of skin and soft tissue infections in the intensive care unit: a review. Intensive Care Med. 2016;42(12):1899\u2013911.","journal-title":"Intensive Care Med"},{"issue":"6","key":"297_CR6","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1001\/jamadermatol.2017.0159","volume":"153","author":"DR Cranendonk","year":"2017","unstructured":"Cranendonk DR, van Vught LA, Wiewel MA, et al. Clinical characteristics and outcomes of patients with cellulitis requiring intensive care. JAMA Dermatol. 2017;153(6):578\u201382.","journal-title":"JAMA Dermatol"},{"issue":"9","key":"297_CR7","doi-asserted-by":"publisher","first-page":"E377","DOI":"10.1111\/1469-0691.12235","volume":"19","author":"J Garau","year":"2013","unstructured":"Garau J, Ostermann H, Medina J, et al. Current management of patients hospitalized with complicated skin and soft tissue infections across Europe (2010\u20132011): assessment of clinical practice patterns and real-life effectiveness of antibiotics from the REACH study. Clin Microbiol Infect. 2013;19(9):E377\u2013E385385.","journal-title":"Clin Microbiol Infect"},{"issue":"Suppl 2","key":"297_CR8","doi-asserted-by":"publisher","first-page":"S84","DOI":"10.1086\/321862","volume":"33","author":"RL Nichols","year":"2001","unstructured":"Nichols RL, Florman S. Clinical presentations of soft-tissue infections and surgical site infections. Clin Infect Dis. 2001;33(Suppl 2):S84\u2013S93.","journal-title":"Clin Infect Dis"},{"issue":"10","key":"297_CR9","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1586\/eri.12.112","volume":"10","author":"MW Garrison","year":"2012","unstructured":"Garrison MW, Kawamura NM, Wen MM. Ceftaroline fosamil: a new cephalosporin active against resistant Gram-positive organisms including MRSA. Expert Rev Anti Infect Ther. 2012;10(10):1087\u2013103.","journal-title":"Expert Rev Anti Infect Ther"},{"issue":"17","key":"297_CR10","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1007\/s40265-016-0654-4","volume":"76","author":"LJ Scott","year":"2016","unstructured":"Scott LJ. Ceftaroline fosamil: a review in complicated skin and soft tissue infections and community-acquired pneumonia. Drugs. 2016;76(17):1659\u201374.","journal-title":"Drugs"},{"issue":"Suppl 4","key":"297_CR11","first-page":"iv41","volume":"65","author":"GR Corey","year":"2010","unstructured":"Corey GR, Wilcox MH, Talbot GH, Thye D, Friedland D, Baculik T. CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother. 2010;65(Suppl 4):iv41\u2013iv51.","journal-title":"J Antimicrob Chemother."},{"issue":"suppl 4","key":"297_CR12","first-page":"iv53","volume":"65","author":"MH Wilcox","year":"2010","unstructured":"Wilcox MH, Corey GR, Talbot GH, Thye D, Friedland D, Baculik T. CANVAS 2: the second phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother. 2010;65(suppl 4):iv53\u2013iv65.","journal-title":"J Antimicrob Chemother."},{"issue":"12","key":"297_CR13","doi-asserted-by":"publisher","first-page":"3575","DOI":"10.1093\/jac\/dkw333","volume":"71","author":"M Dryden","year":"2016","unstructured":"Dryden M, Zhang Y, Wilson D, Iaconis JP, Gonzalez J. A Phase III, randomized, controlled, non-inferiority trial of ceftaroline fosamil 600 mg every 8 h versus vancomycin plus aztreonam in patients with complicated skin and soft tissue infection with systemic inflammatory response or underlying comorbidities. J Antimicrob Chemother. 2016;71(12):3575\u201384.","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"297_CR14","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1159\/000180580","volume":"16","author":"DW Cockcroft","year":"1976","unstructured":"Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31\u201341.","journal-title":"Nephron"},{"key":"297_CR15","unstructured":"Food and Drug Administration. Guidance for Industry Acute Bacterial Skin and Skin Structure Infections: Developing Drugs for Treatment. 2013. https:\/\/www.fda.gov\/downloads\/Drugs\/Guidances\/ucm071185.pdf. Accessed 22 Nov 2018."},{"key":"297_CR16","unstructured":"European Committee on Antimicrobial Susceptibility Testing (EUCAST). Clinical breakpoints for bacteria, v 9.0. 2019. https:\/\/www.eucast.org\/clinical_breakpoints\/. Accessed 11 Nov 2019."},{"key":"297_CR17","unstructured":"Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing. Twenty-ninth informational supplement M100-S29. 2019. https:\/\/clsi.org\/standards\/products\/microbiology\/documents\/m100\/. Accessed 21 Jun 2019."},{"issue":"2","key":"297_CR18","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1155\/2008\/846453","volume":"19","author":"V Ki","year":"2008","unstructured":"Ki V, Rotstein C. Bacterial skin and soft tissue infections in adults: A review of their epidemiology, pathogenesis, diagnosis, treatment and site of care. Can J Infect Dis Med Microbiol. 2008;19(2):173\u201384.","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"297_CR19","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/1471-2334-10-151","volume":"10","author":"HN Shen","year":"2010","unstructured":"Shen HN, Lu CL. Skin and soft tissue infections in hospitalized and critically ill patients: a nationwide population-based study. BMC Infect Dis. 2010;10:151.","journal-title":"BMC Infect Dis"},{"issue":"2","key":"297_CR20","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s40121-019-0242-5","volume":"8","author":"KC Claeys","year":"2019","unstructured":"Claeys KC, Zasowski EJ, Trinh TD, et al. Open-Label Randomized trial of early clinical outcomes of Ceftaroline Fosamil versus vancomycin for the treatment of acute bacterial skin and skin structure infections at risk of methicillin-resistant Staphylococcus aureus. Infect Dis Ther. 2019;8(2):199\u2013208.","journal-title":"Infect Dis Ther"},{"issue":"2","key":"297_CR21","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1128\/JCM.05817-11","volume":"50","author":"MJ Zervos","year":"2012","unstructured":"Zervos MJ, Freeman K, Vo L, et al. Epidemiology and outcomes of complicated skin and soft tissue infections in hospitalized patients. J Clin Microbiol. 2012;50(2):238\u201345.","journal-title":"J Clin Microbiol"},{"issue":"2","key":"297_CR22","doi-asserted-by":"publisher","first-page":"195","DOI":"10.5935\/0103-507X.20170019","volume":"29","author":"LF Malheiro","year":"2017","unstructured":"Malheiro LF, Magano R, Ferreira A, Sarmento A, Santos L. Skin and soft tissue infections in the intensive care unit: a retrospective study in a tertiary care center. Rev Bras Ter Intensiva. 2017;29(2):195\u2013205.","journal-title":"Rev Bras Ter Intensiva"}],"container-title":["Infectious Diseases and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-020-00297-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40121-020-00297-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-020-00297-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T06:30:36Z","timestamp":1715668236000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40121-020-00297-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,30]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["297"],"URL":"https:\/\/doi.org\/10.1007\/s40121-020-00297-3","relation":{},"ISSN":["2193-8229","2193-6382"],"issn-type":[{"type":"print","value":"2193-8229"},{"type":"electronic","value":"2193-6382"}],"subject":[],"published":{"date-parts":[[2020,6,30]]},"assertion":[{"value":"31 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}