{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:50:16Z","timestamp":1740167416101,"version":"3.37.3"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,4,11]],"date-time":"2021-04-11T00:00:00Z","timestamp":1618099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2021,4,11]],"date-time":"2021-04-11T00:00:00Z","timestamp":1618099200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100013276","name":"Interreg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013276","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CM18\/00132","FI19\/00133","PI18\/01061","FIS PI18\/01061"],"award-info":[{"award-number":["CM18\/00132","FI19\/00133","PI18\/01061","FIS PI18\/01061"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Ther"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s40121-021-00445-3","type":"journal-article","created":{"date-parts":[[2021,4,11]],"date-time":"2021-04-11T15:02:36Z","timestamp":1618153356000},"page":"955-970","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Characteristics and Outcome of Bloodstream Infections in HIV-Infected Patients with Cancer and Febrile Neutropenia: A Case\u2013Control Study"],"prefix":"10.1007","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2490-0217","authenticated-orcid":false,"given":"Pedro","family":"Puerta-Alcalde","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Ambrosioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Chumbita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Hern\u00e1ndez-Meneses","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Garcia-Pouton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia","family":"Cardozo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estela","family":"Moreno-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesc","family":"Marco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Mensa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Montserrat","family":"Rovira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordi","family":"Esteve","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose A.","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Mallolas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Soriano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M.","family":"Mir\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Garcia-Vidal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,4,11]]},"reference":[{"key":"445_CR1","doi-asserted-by":"crossref","unstructured":"Klastersky J, Ameye L, Maertens J, Georgala A, Muanza F, Aoun M, et al. Bacteraemia in febrile neutropenic cancer patients. Int J Antimicrob Agents 2007; 30:51\u20139. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17689933","DOI":"10.1016\/j.ijantimicag.2007.06.012"},{"key":"445_CR2","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1111\/j.1469-0691.2005.01298.x","volume":"12","author":"M N\u00f8rgaard","year":"2006","unstructured":"N\u00f8rgaard M, Larsson H, Pedersen G, Sch\u00f8nheyder HC, S\u00f8rensen HT. Risk of bacteraemia and mortality in patients with haematological malignancies. Clin Microbiol Infect. 2006;12:217\u201323 ((European Society of Clinical Infectious Diseases)).","journal-title":"Clin Microbiol Infect"},{"key":"445_CR3","doi-asserted-by":"crossref","unstructured":"Gudiol C, Tubau F, Calatayud L, Garcia-Vidal C, Cisnal M, Sanchez-Ortega I, et al. Bacteraemia due to multidrug-resistant Gram-negative bacilli in cancer patients: risk factors, antibiotic therapy and outcomes. J Antimicrob Chemother 2011; 66:657\u201363. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21193475","DOI":"10.1093\/jac\/dkq494"},{"issue":"11","key":"445_CR4","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1093\/cid\/cix646","volume":"65","author":"D Averbuch","year":"2017","unstructured":"Averbuch D, Tridello G, Hoek J, Mikulska M, Akan H, Yanez San Segundo L, et al. Antimicrobial resistance in Gram-negative rods causing bacteremia in hematopoietic stem cell transplant patients: intercontinental prospective study of Infectious Diseases Working Party of the European Bone Marrow Transplantation group. Clin Infect Dis. 2017;65(11):1819\u201328.","journal-title":"Clin Infect Dis"},{"key":"445_CR5","doi-asserted-by":"publisher","unstructured":"Garcia-Vidal C, Cardozo-Espinola C, Puerta-Alcalde P, Marco F, Tellez A, Ag\u00fc Ero D, et al. Risk factors for mortality in patients with acute leukemia and bloodstream infections in the era of multiresistance. PLoS One 2018; 13:1\u201312. Available from: http:\/\/journals.plos.org\/plosone\/article\/file?id=https:\/\/doi.org\/10.1371\/journal.pone.0199531&type=printable","DOI":"10.1371\/journal.pone.0199531&type=printable"},{"key":"445_CR6","doi-asserted-by":"publisher","unstructured":"Martinez-Nadal G, Puerta-Alcalde P, Gudiol C, Cardozo C, Albasanz-Puig A, Marco F et al. Inappropriate empirical antibiotic treatment in high-risk neutropenic patients with bacteremia in the era of multidrug resistance. Clin Infect Dis 2019; Available from: https:\/\/academic.oup.com\/cid\/advance-article\/. Doi: https:\/\/doi.org\/10.1093\/cid\/ciz319\/5479518","DOI":"10.1093\/cid\/ciz319\/5479518"},{"key":"445_CR7","doi-asserted-by":"crossref","unstructured":"Goedert JJ, Cot\u00e9 TR, Virgo P, Scoppa SM, Kingma DW, Gail MH et al. Spectrum of AIDS-associated malignant disorders. Lancet 1998; 351:1833\u20139. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9652666","DOI":"10.1016\/S0140-6736(97)09028-4"},{"key":"445_CR8","doi-asserted-by":"crossref","unstructured":"Frisch M, Biggar RJ, Engels EA, Goedert JJ, AIDS-Cancer Match Registry Study Group. Association of cancer with AIDS-related immunosuppression in adults. JAMA 2001; 285:1736\u201345. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11277828","DOI":"10.1001\/jama.285.13.1736"},{"key":"445_CR9","unstructured":"Centers for Disease Control and Prevention. HIV Surveillance Report, 2017; 29"},{"key":"445_CR10","doi-asserted-by":"crossref","unstructured":"Palella FJ, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med. 1998; 338:853\u201360. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9516219","DOI":"10.1056\/NEJM199803263381301"},{"key":"445_CR11","doi-asserted-by":"crossref","unstructured":"Trickey A, May MT, Vehreschild J-J, Obel N, Gill MJ, Crane HM et al. Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies. Lancet HIV. 2017; 4:e349\u201356. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28501495","DOI":"10.1016\/S2352-3018(17)30066-8"},{"key":"445_CR12","doi-asserted-by":"crossref","unstructured":"Cobucci RNO, Lima PH, de Souza PC, Costa VV, Cornetta M da C de M, Fernandes JV, et al. Assessing the impact of HAART on the incidence of defining and non-defining AIDS cancers among patients with HIV\/AIDS: a systematic review. J Infect Public Health. 2015; 8:1\u201310. Available from: https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876034114001415","DOI":"10.1016\/j.jiph.2014.08.003"},{"key":"445_CR13","doi-asserted-by":"crossref","unstructured":"Engels EA, Biggar RJ, Hall HI, Cross H, Crutchfield A, Finch JL et al. Cancer risk in people infected with human immunodeficiency virus in the United States. Int J Cancer 2008; 123:187\u201394. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18435450","DOI":"10.1002\/ijc.23487"},{"key":"445_CR14","doi-asserted-by":"crossref","unstructured":"Robbins HA, Shiels MS, Pfeiffer RM, Engels EA. Epidemiologic contributions to recent cancer trends among HIV-infected people in the United States. AIDS 2014; 28:881\u201390. Available from: https:\/\/insights.ovid.com\/crossref?an=00002030-201403270-00010","DOI":"10.1097\/QAD.0000000000000163"},{"key":"445_CR15","doi-asserted-by":"crossref","unstructured":"Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. Incidence of cancers in people with HIV\/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 2007; 370:59\u201367. Available from: https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0140673607610502","DOI":"10.1016\/S0140-6736(07)61050-2"},{"key":"445_CR16","doi-asserted-by":"crossref","unstructured":"Coghill AE, Pfeiffer RM, Shiels MS, Engels EA. Excess mortality among HIV-infected individuals with cancer in the United States. Cancer Epidemiol Biomark Prev 2017; 26:1027\u201333. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28619832","DOI":"10.1158\/1055-9965.EPI-16-0964"},{"key":"445_CR17","doi-asserted-by":"crossref","unstructured":"Freifeld AG, Bow EJ, Sepkowitz KA, Boeckh MJ, Ito JI, Mullen CA et al. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 Update by the Infectious Diseases Society of America. Clin Infect Dis 2011; 52:352\u20133. Oxford University Press. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21205990","DOI":"10.1093\/cid\/ciq147"},{"key":"445_CR18","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.cmi.2019.07.002","volume":"26","author":"D Viasus","year":"2020","unstructured":"Viasus D, Puerta-Alcalde P, Cardozo C, Su\u00e1rez-Lled\u00f3 M, Rodr\u00edguez-N\u00fa\u00f1ez O, Morata L, et al. Predictors of multidrug-resistant Pseudomonas aeruginosa in neutropenic patients with bloodstream infection. Clin Microbiol Infect. 2020;26:345\u201350 ((Elsevier B.V.)).","journal-title":"Clin Microbiol Infect"},{"key":"445_CR19","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1038\/s41409-019-0701-3","volume":"55","author":"P Puerta-Alcalde","year":"2020","unstructured":"Puerta-Alcalde P, Cardozo C, Marco F, Su\u00e1rez-Lled\u00f3 M, Moreno E, Morata L, et al. Changing epidemiology of bloodstream infection in a 25-years hematopoietic stem cell transplant program: current challenges and pitfalls on empiric antibiotic treatment impacting outcomes. Bone Marrow Transplant. 2020;55:603\u201312 ((Springer Nature)).","journal-title":"Bone Marrow Transplant"},{"key":"445_CR20","doi-asserted-by":"crossref","unstructured":"Marschall J, Mermel LA, Fakih M, Hadaway L, Kallen A, O\u2019Grady NP et al. Strategies to prevent central line\u2013associated bloodstream infections in acute care hospitals: 2014 Update. Infect Control Hosp Epidemiol. 2014; 35:753\u201371. Cambridge University Press, Cambridge. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/24915204\/","DOI":"10.1086\/676533"},{"key":"445_CR21","doi-asserted-by":"publisher","first-page":"684","DOI":"10.7326\/M17-2082","volume":"168","author":"S Singh","year":"2018","unstructured":"Singh S, Song R, Johnson AS, McCray E, Hall HI. HIV incidence, prevalence, and undiagnosed infections in US Men who have sex with men. Ann Intern Med. 2018;168:684\u201394 ((American College of Physicians)).","journal-title":"Ann Intern Med"},{"key":"445_CR22","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.critrevonc.2008.10.013","volume":"1","author":"N Mounier","year":"2009","unstructured":"Mounier N, Katlama C, Costagliola D, Chichmanian RM, Spano JP. Drug interactions between antineoplastic and antiretroviral therapies: Implications and management for clinical practice. Crit Rev Oncol Hematol. 2009;1:10\u201320.","journal-title":"Crit Rev Oncol Hematol"},{"key":"445_CR23","doi-asserted-by":"publisher","first-page":"773","DOI":"10.3851\/IMP2961","volume":"20","author":"JL Casado","year":"2015","unstructured":"Casado JL, Machuca I, Ba\u00f1\u00f3n S, Moreno A, Molt\u00f3 J, Rodriguez MA. Raltegravir plus two nucleoside analogues as combination antiretroviral therapy in HIV-infected patients who require cancer chemotherapy. Antivir Ther. 2015;20:773\u20137 ((International Medical Press Ltd)).","journal-title":"Antivir Ther"},{"key":"445_CR24","doi-asserted-by":"publisher","first-page":"O672","DOI":"10.1111\/1469-0691.12589","volume":"20","author":"HA Torres","year":"2014","unstructured":"Torres HA, Rallapalli V, Saxena A, Granwehr BP, Viola GM, Ariza-Heredia E, et al. Efficacy and safety of antiretrovirals in HIV-infected patients with cancer. Clin Microbiol Infect. 2014;20:O672\u20139 ((Blackwell Publishing Ltd)).","journal-title":"Clin Microbiol Infect"},{"key":"445_CR25","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S0924-8579(99)00036-9","volume":"1","author":"S Sch\u00f6nwald","year":"1999","unstructured":"Sch\u00f6nwald S, Begovac J, Skerk V. Urinary tract infections in HIV disease. Int J Antimicrob Agents. 1999;1:309\u201311.","journal-title":"Int J Antimicrob Agents"},{"key":"445_CR26","doi-asserted-by":"crossref","unstructured":"Declercq S, De Munter P, Derdelinckx I, Verhaegen J, Peetermans WE, Vanderschueren S, et al. Characteristics, causes, and outcome of 54 episodes of bloodstream infections in a cohort of HIV patients. Infect Dis (Auckl). 2015; 47:611\u20137. Taylor and Francis, London. Available from: http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25875395","DOI":"10.3109\/23744235.2015.1033002"},{"key":"445_CR27","doi-asserted-by":"publisher","unstructured":"Shi X, Sims MD, Hanna MM, Xie M, Gulick PG, Zheng Y-H, et al. Neutropenia during HIV Infection: adverse consequences and remedies. Int Rev Immunol. 2014; 33:511\u201336. Available from: http:\/\/www.tandfonline.com\/doi\/full\/. Doi: https:\/\/doi.org\/10.3109\/08830185.2014.893301","DOI":"10.3109\/08830185.2014.893301"},{"key":"445_CR28","doi-asserted-by":"publisher","first-page":"2675","DOI":"10.1002\/cncr.20688","volume":"101","author":"C Borg","year":"2004","unstructured":"Borg C, Ray-Coquard I, Philip I, Clapisson G, Bendriss-Vermare N, Menetrier-Caux C, et al. CD4 lymphopenia as a risk factor for febrile neutropenia and early death after cytotoxic chemotherapy in adult patients with cancer. Cancer. 2004;101:2675\u201380 (Wiley, New York).","journal-title":"Cancer"}],"container-title":["Infectious Diseases and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-021-00445-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40121-021-00445-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-021-00445-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T19:27:49Z","timestamp":1620847669000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40121-021-00445-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,11]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["445"],"URL":"https:\/\/doi.org\/10.1007\/s40121-021-00445-3","relation":{},"ISSN":["2193-8229","2193-6382"],"issn-type":[{"type":"print","value":"2193-8229"},{"type":"electronic","value":"2193-6382"}],"subject":[],"published":{"date-parts":[[2021,4,11]]},"assertion":[{"value":"28 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}