{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T13:12:34Z","timestamp":1769346754361,"version":"3.49.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T00:00:00Z","timestamp":1638403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T00:00:00Z","timestamp":1638403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Spanish Network for Research in Infectious Diseases","award":["REIPI RD16\/0016\/0005"],"award-info":[{"award-number":["REIPI RD16\/0016\/0005"]}]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de enfermedades infecciosas","award":["CB\/21\/13\/00009"],"award-info":[{"award-number":["CB\/21\/13\/00009"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Ther"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1007\/s40121-021-00575-8","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T13:04:05Z","timestamp":1638450245000},"page":"323-334","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Bloodstream Infection and Endocarditis Caused by Staphylococcus aureus in Patients with Cancer: A Multicenter Cohort Study"],"prefix":"10.1007","volume":"11","author":[{"given":"Sara","family":"Grillo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Cuervo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falia","family":"Laporte-Amarg\u00f3s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manel","family":"Tuells","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Immaculada","family":"Grau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e0maris","family":"Berbel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlota","family":"Gudiol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miquel","family":"Pujol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordi","family":"Carratal\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,12,2]]},"reference":[{"key":"575_CR1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03903.x","author":"KB Laupland","year":"2013","unstructured":"Laupland KB, Lyytik\u00e4inen O, S\u00f8gaard M, et al. The changing epidemiology of Staphylococcus aureus bloodstream infection: a multinational population-based surveillance study. Clin Microbiol Infect. 2013. https:\/\/doi.org\/10.1111\/j.1469-0691.2012.03903.x.","journal-title":"Clin Microbiol Infect"},{"key":"575_CR2","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.1093\/cid\/ciz112","volume":"69","author":"M Souli","year":"2019","unstructured":"Souli M, Ruffin F, Choi SH, et al. Changing characteristics of Staphylococcus aureus Bacteremia: results from a 21-year, prospective, longitudinal study. Clin Infect Dis. 2019;69:1868\u201377. https:\/\/doi.org\/10.1093\/cid\/ciz112.","journal-title":"Clin Infect Dis"},{"key":"575_CR3","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1128\/CMR.05022-11","volume":"25","author":"SJ van Hal","year":"2012","unstructured":"van Hal SJ, Jensen SO, Vaska VL, Espedido BA, Paterson DL, Gosbell IB. Predictors of mortality in Staphylococcus aureus bacteremia. Clin Microbiol Rev. 2012;25:362\u201386. https:\/\/doi.org\/10.1128\/CMR.05022-11.","journal-title":"Clin Microbiol Rev"},{"key":"575_CR4","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.1093\/eurheartj\/ehz620","volume":"40","author":"G Habib","year":"2019","unstructured":"Habib G, Erba PA, Iung B, et al. Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European Infective Endocarditis) registry: a prospective cohort study. Eur Heart J. 2019;40:3222-3232B. https:\/\/doi.org\/10.1093\/eurheartj\/ehz620.","journal-title":"Eur Heart J"},{"key":"575_CR5","doi-asserted-by":"publisher","first-page":"3237","DOI":"10.1093\/eurheartj\/ehz327","volume":"40","author":"L \u00d8stergaard","year":"2019","unstructured":"\u00d8stergaard L, Bruun NE, Voldstedlund M, et al. Prevalence of infective endocarditis in patients with positive blood cultures: a Danish nationwide study. Eur Heart J. 2019;40:3237\u201344. https:\/\/doi.org\/10.1093\/eurheartj\/ehz327.","journal-title":"Eur Heart J"},{"key":"575_CR6","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.jinf.2009.07.015","volume":"59","author":"S Rieg","year":"2009","unstructured":"Rieg S, Peyerl-Hoffmann G, de With K, et al. Mortality of S.\u00a0aureus bacteremia and infectious diseases specialist consultation\u2014a study of 521 patients in Germany. J Infect. 2009;59:232\u20139. https:\/\/doi.org\/10.1016\/j.jinf.2009.07.015.","journal-title":"J Infect"},{"key":"575_CR7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021217","author":"SJ van Hal","year":"2011","unstructured":"van Hal SJ, Jones M, Gosbell IB, Paterson DL. Vancomycin heteroresistance is associated with reduced mortality in ST239 methicillin-resistant Staphylococcus aureus blood stream infections. PLoS ONE. 2011. https:\/\/doi.org\/10.1371\/journal.pone.0021217.","journal-title":"PLoS ONE"},{"key":"575_CR8","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209\u201349. https:\/\/doi.org\/10.3322\/caac.21660.","journal-title":"CA Cancer J Clin"},{"key":"575_CR9","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1056\/nejmoa022139","volume":"348","author":"GS Martin","year":"2003","unstructured":"Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003;348:1546\u201354. https:\/\/doi.org\/10.1056\/nejmoa022139.","journal-title":"N Engl J Med"},{"key":"575_CR10","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/J.BJID.2012.10.001","volume":"16","author":"M Primo","year":"2012","unstructured":"Primo M, Guilarde A, Martelli C, Batista L, Turchi M. Healthcare-associated Staphylococcus aureus bloodstream infection: length of stay, attributable mortality, and additional direct costs. Braz J Infect Dis. 2012;16:503\u20139. https:\/\/doi.org\/10.1016\/J.BJID.2012.10.001.","journal-title":"Braz J Infect Dis"},{"key":"575_CR11","doi-asserted-by":"publisher","first-page":"2371","DOI":"10.1007\/s00520-011-1353-z","volume":"20","author":"CI Kang","year":"2012","unstructured":"Kang CI, Song JH, Chung DR, et al. Bloodstream infections in adult patients with cancer: clinical features and pathogenic significance of Staphylococcus aureus bacteremia. Support Care Cancer. 2012;20:2371\u20138. https:\/\/doi.org\/10.1007\/s00520-011-1353-z.","journal-title":"Support Care Cancer"},{"key":"575_CR12","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1086\/374339","volume":"36","author":"H Wisplinghoff","year":"2003","unstructured":"Wisplinghoff H, Seifert H, Wenzel RP, Edmond MB. Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States. Clin Infect Dis. 2003;36:1103\u201310. https:\/\/doi.org\/10.1086\/374339.","journal-title":"Clin Infect Dis"},{"key":"575_CR13","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1097\/MD.0000000000000026","volume":"93","author":"M Mar\u00edn","year":"2014","unstructured":"Mar\u00edn M, Gudiol C, Garcia-Vidal C, Ardanuy C, Carratal\u00e0 J. Bloodstream infections in patients with solid tumors: epidemiology, antibiotic therapy, and outcomes in 528 episodes in a single cancer center. Medicine (US). 2014;93:143\u20139. https:\/\/doi.org\/10.1097\/MD.0000000000000026.","journal-title":"Medicine (US)"},{"key":"575_CR14","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/PL00011241","volume":"20","author":"E Gonz\u00e1lez-Barca","year":"2001","unstructured":"Gonz\u00e1lez-Barca E, Carratal\u00e1 J, Mykietiuk A, Fern\u00e1ndez-Sevilla A, Gudiol F. Predisposing factors and outcome of Staphylococcus aureus bacteremia in neutropenic patients with cancer. Eur J Clin Microbiol Infect Dis. 2001;20:117\u20139. https:\/\/doi.org\/10.1007\/PL00011241.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"575_CR15","doi-asserted-by":"publisher","first-page":"4057","DOI":"10.1007\/s00520-018-4275-1","volume":"26","author":"OY Bello-Chavolla","year":"2018","unstructured":"Bello-Chavolla OY, Bahena-Lopez JP, Garciadiego-Fosass P, et al. Bloodstream infection caused by S.\u00a0aureus in patients with cancer: a 10-year longitudinal single-center study. Support Care Cancer. 2018;26:4057\u201365. https:\/\/doi.org\/10.1007\/s00520-018-4275-1.","journal-title":"Support Care Cancer"},{"key":"575_CR16","doi-asserted-by":"publisher","first-page":"3083","DOI":"10.1007\/s00520-018-4162-9","volume":"26","author":"Z Loh","year":"2018","unstructured":"Loh Z, Estacio O, Grigg A, Holmes NE, Chong G, Hawkes EA. Echocardiography has low utility in cancer patients with Staphylococcus aureus bacteraemia: findings from a retrospective study. Support Care Cancer. 2018;26:3083\u20139. https:\/\/doi.org\/10.1007\/s00520-018-4162-9.","journal-title":"Support Care Cancer"},{"key":"575_CR17","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1093\/cid\/ciz018","volume":"69","author":"S Grillo","year":"2019","unstructured":"Grillo S, Cuervo G, Carratal\u00e0 J, et al. Impact of \u03b2-lactam and daptomycin combination therapy on clinical outcomes in methicillin-susceptible Staphylococcus aureus bacteremia: a propensity score-matched analysis. Clin Infect Dis. 2019;69:1480\u20138. https:\/\/doi.org\/10.1093\/cid\/ciz018.","journal-title":"Clin Infect Dis"},{"key":"575_CR18","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa216","author":"S Grillo","year":"2020","unstructured":"Grillo S, Cuervo G, Carratal\u00e0 J, et al. Characteristics and outcomes of staphylococcus aureus bloodstream infection originating from the urinary tract: a multicenter cohort study. Open Forum Infect Dis. 2020. https:\/\/doi.org\/10.1093\/ofid\/ofaa216.","journal-title":"Open Forum Infect Dis"},{"key":"575_CR19","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373\u201383. https:\/\/doi.org\/10.1016\/0021-9681(87)90171-8.","journal-title":"J Chronic Dis"},{"key":"575_CR20","doi-asserted-by":"publisher","DOI":"10.1097\/00019048-200206000-00016","author":"ND Friedman","year":"2002","unstructured":"Friedman ND, Kaye KS, Stout JE, et al. Health care-associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med. 2002. https:\/\/doi.org\/10.1097\/00019048-200206000-00016.","journal-title":"Ann Intern Med"},{"key":"575_CR21","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jama.2016.0287","volume":"315","author":"M Singer","year":"2016","unstructured":"Singer M, Deutschman CS, Seymour C, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315:801\u201310. https:\/\/doi.org\/10.1001\/jama.2016.0287.","journal-title":"JAMA"},{"key":"575_CR22","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1086\/313753","volume":"30","author":"JS Li","year":"2000","unstructured":"Li JS, Sexton DJ, Mick N, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000;30:633\u20138. https:\/\/doi.org\/10.1086\/313753.","journal-title":"Clin Infect Dis"},{"key":"575_CR23","unstructured":"European Committee on Antimicrobial Susceptibility Testing Breakpoint tables for interpretation of MICs and zone diameters n.d. 2021, v 11.0. https:\/\/www.eucast.org\/clinical_breakpoints\/."},{"key":"575_CR24","doi-asserted-by":"publisher","first-page":"563","DOI":"10.3109\/00365549509047068","volume":"27","author":"R Skov","year":"1995","unstructured":"Skov R, Gottschau A, Skinh\u00f8j P, et al. Staphylococcus aureus bacteremia: a 14-year nationwide study in hematological patients with malignant disease or agranulocytosis. J Infect Dis. 1995;27:563\u20138. https:\/\/doi.org\/10.3109\/00365549509047068.","journal-title":"J Infect Dis"},{"key":"575_CR25","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1002\/cncr.11882","volume":"100","author":"J Crawford","year":"2004","unstructured":"Crawford J, Dale DC, Lyman GH. Chemotherapy-induced neutropenia: risks, consequences, and new directions for its management. Cancer. 2004;100:228\u201337. https:\/\/doi.org\/10.1002\/cncr.11882.","journal-title":"Cancer"},{"key":"575_CR26","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1093\/cid\/civ235","volume":"61","author":"BR Palraj","year":"2015","unstructured":"Palraj BR, Baddour LM, Hess EP, et al. Predicting risk of endocarditis using a clinical tool (PREDICT): scoring system to guide use of echocardiography in the management of Staphylococcus aureus bacteremia. Clin Infect Dis. 2015;61:18\u201328. https:\/\/doi.org\/10.1093\/cid\/civ235.","journal-title":"Clin Infect Dis"},{"key":"575_CR27","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.4065\/82.10.1165","volume":"82","author":"EE Hill","year":"2007","unstructured":"Hill EE, Vanderschueren S, Verhaegen J, et al. Risk factors for infective endocarditis and outcome of patients with Staphylococcus aureus bacteremia. Mayo Clin Proc. 2007;82:1165\u20139. https:\/\/doi.org\/10.4065\/82.10.1165.","journal-title":"Mayo Clin Proc"},{"key":"575_CR28","doi-asserted-by":"publisher","first-page":"3248","DOI":"10.1093\/eurheartj\/ehz175","volume":"40","author":"L Liesenborghs","year":"2019","unstructured":"Liesenborghs L, Meyers S, Lox M, et al. Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves. Eur Heart J. 2019;40:3248\u201359. https:\/\/doi.org\/10.1093\/eurheartj\/ehz175.","journal-title":"Eur Heart J"},{"key":"575_CR29","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1182\/blood-2014-02-558890","volume":"124","author":"J Claes","year":"2014","unstructured":"Claes J, Peetermans M, Liesenborghs L, et al. Adhesion of Staphylococcus aureus to the vessel wall under flow is mediated by von Willebrand factor-binding protein. Blood. 2014;124:1669\u201376. https:\/\/doi.org\/10.1182\/blood-2014-02-558890.","journal-title":"Blood"},{"key":"575_CR30","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1093\/infdis\/jiu426","volume":"211","author":"TR Veloso","year":"2015","unstructured":"Veloso TR, Que Y-AA, Chaouch A, et al. Prophylaxis of experimental endocarditis with antiplatelet and antithrombin agents: a role for long-term prevention of infective endocarditis in humans? J Infect Dis. 2015;211:72\u20139. https:\/\/doi.org\/10.1093\/infdis\/jiu426.","journal-title":"J Infect Dis"},{"key":"575_CR31","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1093\/cid\/ciaa661","volume":"73","author":"JH Butt","year":"2021","unstructured":"Butt JH, Fosb\u00f8l EL, Verhamme P, et al. Dabigatran and the risk of Staphylococcus aureus bacteremia: a nationwide cohort study. Clin Infect Dis. 2021;73:480\u20136. https:\/\/doi.org\/10.1093\/cid\/ciaa661.","journal-title":"Clin Infect Dis"}],"container-title":["Infectious Diseases and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-021-00575-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40121-021-00575-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-021-00575-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T17:38:40Z","timestamp":1644946720000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40121-021-00575-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,2]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["575"],"URL":"https:\/\/doi.org\/10.1007\/s40121-021-00575-8","relation":{},"ISSN":["2193-8229","2193-6382"],"issn-type":[{"value":"2193-8229","type":"print"},{"value":"2193-6382","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,2]]},"assertion":[{"value":"8 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}