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Written informed consent, including the consent to publish the study results, was obtained from all patients or their legal surrogate as soon as possible and during the acute phase of the treatment period, according to national legislation. Subsequently, for patients where immediate consent was not possible, we obtained consent from the patient when possible []. The study was conducted in accordance with the World Medical Association\u2019s Code of Ethics (Declaration of Helsinki 1964 and its later amendments). The INFECT study was approved at all involved study centers under the governance of the Regionala etikpr\u00f6vningsn\u00e4mnden i G\u00f6teborg \u2013 V\u00e4stra G\u00f6talandsregionen Dnr 930\u201312, Den Nationale Videnskabs Etiske Kommitte (DNVK \u2013 sag nr. 1211709, dok.nr. 1151739) and the REK \u2013 Regionale Komiteer for medisinsk og helsefaglig forskningsetikk, ref. 2012\/2227\/REK vest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}