{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T13:12:50Z","timestamp":1779973970018,"version":"3.53.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100020955","name":"GlaxoSmithKline Biologicals SA","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100020955","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Ther"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s40121-026-01323-6","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T15:32:57Z","timestamp":1776353577000},"page":"1689-1704","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Estimation of Costs Related to the Management of Herpes Zoster and its Complications in Vietnam: A Medical Chart Review"],"prefix":"10.1007","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3953-7473","authenticated-orcid":false,"given":"Nurilign","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5513-6832","authenticated-orcid":false,"given":"Van M.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7723-7238","authenticated-orcid":false,"given":"Anh C.","family":"Pham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8475-2530","authenticated-orcid":false,"given":"Nam H.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2782-8775","authenticated-orcid":false,"given":"Minh","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7437-1608","authenticated-orcid":false,"given":"Son T.","family":"Tran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8717-9848","authenticated-orcid":false,"given":"Nguyen T.","family":"Tran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9982-9905","authenticated-orcid":false,"given":"Doanh H.","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3940-4778","authenticated-orcid":false,"given":"Quyen T. L.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6020-4694","authenticated-orcid":false,"given":"Nhan T.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3153-085X","authenticated-orcid":false,"given":"Thanh D.","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2191-6408","authenticated-orcid":false,"given":"Huong T. T.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,16]]},"reference":[{"key":"1323_CR1","unstructured":"U.S. Centers for Disease Control and Prevention. Clinical Overview of Shingles (Herpes Zoster). 2024. https:\/\/www.cdc.gov\/shingles\/hcp\/clinical-overview. Accessed July 2025."},{"issue":"6","key":"1323_CR2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-004833","volume":"4","author":"K Kawai","year":"2014","unstructured":"Kawai K, Gebremeskel BG, Acosta CJ. Systematic review of incidence and complications of herpes zoster: towards a global perspective. BMJ Open. 2014;4(6):e004833.","journal-title":"BMJ Open"},{"issue":"1","key":"1323_CR3","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3395-z","volume":"18","author":"D Curran","year":"2018","unstructured":"Curran D, Schmidt-Ott R, Schutter U, et al. Impact of herpes zoster and postherpetic neuralgia on the quality of life of Germans aged 50 or above. BMC Infect Dis. 2018;18(1):496.","journal-title":"BMC Infect Dis"},{"key":"1323_CR4","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-015-1514-y","volume":"15","author":"A Gater","year":"2015","unstructured":"Gater A, Uhart M, McCool R, Pr\u00e9aud E. The humanistic, economic and societal burden of herpes zoster in Europe: a critical review. BMC Public Health. 2015;15:193.","journal-title":"BMC Public Health"},{"key":"1323_CR5","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.ijid.2013.11.018","volume":"20","author":"H Song","year":"2014","unstructured":"Song H, Lee J, Lee M, et al. Burden of illness, quality of life, and healthcare utilization among patients with herpes zoster in South Korea: a prospective clinical-epidemiological study. Int J Infect Dis. 2014;20:23\u201330.","journal-title":"Int J Infect Dis"},{"issue":"4","key":"1323_CR6","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s10389-010-0323-0","volume":"18","author":"T Weinke","year":"2010","unstructured":"Weinke T, Edte A, Schmitt S, Lukas K. Impact of herpes zoster and post-herpetic neuralgia on patients\u2019 quality of life: a patient-reported outcomes survey. Z Gesundh Wiss. 2010;18(4):367\u201374.","journal-title":"Z Gesundh Wiss"},{"issue":"6","key":"1323_CR7","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1080\/21645515.2020.1847582","volume":"17","author":"D van Oorschot","year":"2021","unstructured":"van Oorschot D, Vroling H, Bunge E, et al. A systematic literature review of herpes zoster incidence worldwide. Hum Vaccin Immunother. 2021;17(6):1714\u201332.","journal-title":"Hum Vaccin Immunother"},{"issue":"1","key":"1323_CR8","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2198-y","volume":"17","author":"LK Chen","year":"2017","unstructured":"Chen LK, Arai H, Chen LY, et al. Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific. BMC Infect Dis. 2017;17(1):213.","journal-title":"BMC Infect Dis"},{"issue":"1","key":"1323_CR9","doi-asserted-by":"publisher","first-page":"245","DOI":"10.4161\/hv.36160","volume":"11","author":"D Panatto","year":"2015","unstructured":"Panatto D, Bragazzi NL, Rizzitelli E, et al. Evaluation of the economic burden of herpes zoster (HZ) infection. Hum Vaccin Immunother. 2015;11(1):245\u201362.","journal-title":"Hum Vaccin Immunother"},{"issue":"1","key":"1323_CR10","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2023.2168952","volume":"19","author":"N Giannelos","year":"2023","unstructured":"Giannelos N, Ng C, Curran D. Cost-effectiveness of the recombinant zoster vaccine (RZV) against herpes zoster: an updated critical review. Hum Vaccin Immunother. 2023;19(1):2168952.","journal-title":"Hum Vaccin Immunother"},{"key":"1323_CR11","unstructured":"Generis Global. An overview of the healthcare system in Vietnam. 2024. https:\/\/generisonline.com\/an-overview-of-the-healthcare-system-in-vietnam. Accessed July 2025."},{"key":"1323_CR12","unstructured":"VGP News. Viet Nam approves three new vaccines for use. 2024. https:\/\/en.baochinhphu.vn\/viet-nam-approves-three-new-vaccines-for-use-111240516160105745.htm. Accessed July 2025."},{"key":"1323_CR13","unstructured":"VGP News. Health Ministry to add four more vaccines to Expanded Immunization Program. 2024. https:\/\/en.baochinhphu.vn\/heath-ministry-to-add-four-more-vaccines-to-expanded-immunization-program-111240610170245145.htm. Accessed Aug 2025."},{"key":"1323_CR14","unstructured":"Vietnamnet Global. Government sustains six socio-economic development zones by 2025. 2022. https:\/\/vietnamnet.vn\/en\/government-sustains-six-socio-economic-development-zones-by-2025-2074657.html. Accessed July 2025."},{"key":"1323_CR15","unstructured":"The Government of Vietnam. Resolution No. 138\/NQ-CP: National master planning for the period of 2021\u20132023, with a vision towards 2050. 2022. https:\/\/thuvienphapluat.vn\/van-ban\/Xay-dung-Do-thi\/Nghi-quyet-138-NQ-CP-2022-Quy-hoach-tong-the-quoc-gia-thoi-ky-2021-2030-tam-nhin-den-2050-534392.aspx. Accessed July 2025."},{"issue":"1","key":"1323_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05648-6","volume":"20","author":"C Mu\u00f1oz-Quiles","year":"2020","unstructured":"Mu\u00f1oz-Quiles C, L\u00f3pez-Lacort M, D\u00edez-Domingo J, Orrico-S\u00e1nchez A. Herpes zoster risk and burden of disease in immunocompromised populations: a population-based study using health system integrated databases, 2009-2014. BMC Infect Dis. 2020;20(1):905.","journal-title":"BMC Infect Dis"},{"key":"1323_CR17","unstructured":"World Bank. Official exchange rate (LCU per US$, period average) - Viet Nam. International Financial Statistics database, International Monetary Fund. 2024. https:\/\/data.worldbank.org\/indicator\/PA.NUS.FCRF?contextual=default&end=2024&locations=VN&start=2023&t=1&view=chart. Accessed July 2025."},{"issue":"1","key":"1323_CR18","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-023-08024-2","volume":"23","author":"LAH Do","year":"2023","unstructured":"Do LAH, Vodicka E, Nguyen A, et al. Estimating the economic burden of respiratory syncytial virus infections in infants in Vietnam: a cohort study. BMC Infect Dis. 2023;23(1):73.","journal-title":"BMC Infect Dis"},{"issue":"4","key":"1323_CR19","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1111\/j.1365-4632.2010.04715.x","volume":"50","author":"K Aunhachoke","year":"2011","unstructured":"Aunhachoke K, Bussaratid V, Chirachanakul P, et al. Measuring herpes zoster, zoster-associated pain, post-herpetic neuralgia-associated loss of quality of life, and healthcare utilization and costs in Thailand. Int J Dermatol. 2011;50(4):428\u201335.","journal-title":"Int J Dermatol"},{"issue":"10","key":"1323_CR20","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1080\/13696998.2016.1187150","volume":"19","author":"BH Johnson","year":"2016","unstructured":"Johnson BH, Palmer L, Gatwood J, et al. Healthcare resource utilization and costs associated with herpes zoster in the US. J Med Econ. 2016;19(10):928\u201335.","journal-title":"J Med Econ"},{"key":"1323_CR21","unstructured":"Vietnamnet Global. New points of the Law on Social Insurance and Health Insurance taking effect from July 1, 2025. 2025. https:\/\/www.vietnam.vn\/en\/nhung-diem-moi-luat-bao-hiem-xa-hoi-bao-hiem-y-te-co-hieu-luc-tu-ngay-1-7-2025. Accessed Sep 2025."},{"key":"1323_CR22","unstructured":"World Health Organization. Health financing in Viet Nam. 2018. https:\/\/www.who.int\/vietnam\/health-topics\/health-financing. Accessed Nov 2025."},{"key":"1323_CR23","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.socscimed.2012.11.028","volume":"96","author":"H Van Minh","year":"2013","unstructured":"Van Minh H, Kim Phuong NT, Saksena P, James CD, Xu K. Financial burden of household out-of pocket health expenditure in Viet Nam: findings from the National Living Standard Survey 2002-2010. Soc Sci Med. 2013;96:258\u201363.","journal-title":"Soc Sci Med"},{"issue":"9","key":"1323_CR24","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-058849","volume":"12","author":"NTT Thuong","year":"2022","unstructured":"Thuong NTT, Huy TQ, Huy DN. Catastrophic health expenditure in the Northern midlands and mountainous areas and its determinants, Vietnam from 2014 to 2020: a cross-sectional study. BMJ Open. 2022;12(9):e058849.","journal-title":"BMJ Open"},{"key":"1323_CR25","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/j.eap.2021.10.009","volume":"72","author":"NTT Thuong","year":"2021","unstructured":"Thuong NTT. Catastrophic health expenditure and impoverishment in Vietnam: evidence from national Household Living Standards Surveys 2008\u20132018. Econ Anal Policy. 2021;72:668\u201384.","journal-title":"Econ Anal Policy"},{"issue":"45","key":"1323_CR26","doi-asserted-by":"publisher","first-page":"6810","DOI":"10.1016\/j.vaccine.2018.08.080","volume":"36","author":"JL Meyers","year":"2018","unstructured":"Meyers JL, Candrilli SD, Rausch DA, et al. Cost of herpes zoster and herpes zoster-related complications among immunocompromised individuals. Vaccine. 2018;36(45):6810\u20138.","journal-title":"Vaccine"},{"issue":"1","key":"1323_CR27","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2185-3","volume":"17","author":"KJ Friesen","year":"2017","unstructured":"Friesen KJ, Chateau D, Falk J, Alessi-Severini S, Bugden S. Cost of shingles: population based burden of disease analysis of herpes zoster and postherpetic neuralgia. BMC Infect Dis. 2017;17(1):69.","journal-title":"BMC Infect Dis"},{"issue":"4","key":"1323_CR28","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.jcv.2010.01.003","volume":"47","author":"WS Choi","year":"2010","unstructured":"Choi WS, Noh JY, Huh JY, et al. Disease burden of herpes zoster in Korea. J Clin Virol. 2010;47(4):325\u20139.","journal-title":"J Clin Virol"},{"issue":"6","key":"1323_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15061174","volume":"15","author":"BX Tran","year":"2018","unstructured":"Tran BX, Thu Vu G, Hoang Nguyen L, et al. Cost-of-illness and the health-related quality of life of patients in the dengue fever outbreak in Hanoi in 2017. Int J Environ Res Public Health. 2018;15(6):1174.","journal-title":"Int J Environ Res Public Health"},{"issue":"10","key":"1323_CR30","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1212\/WNL.0b013e3182a3516e","volume":"81","author":"BP Yawn","year":"2013","unstructured":"Yawn BP, Gilden D. The global epidemiology of herpes zoster. Neurology. 2013;81(10):928\u201330.","journal-title":"Neurology"},{"key":"1323_CR31","unstructured":"Viet Nam News. Hospitals expand electronic records as Vi\u1ec7t Nam pushes toward unified digital health system. 2025. https:\/\/vietnamnews.vn\/society\/1729858\/hospitals-expand-electronic-records-as-viet-nam-pushes-toward-unified-digital-health-system.html. Accessed Jan 2026."},{"issue":"12","key":"1323_CR32","doi-asserted-by":"publisher","first-page":"2865","DOI":"10.1080\/21645515.2019.1627818","volume":"15","author":"L Oostvogels","year":"2019","unstructured":"Oostvogels L, Heineman TC, Johnson RW, et al. Medical conditions at enrollment do not impact efficacy and safety of the adjuvanted recombinant zoster vaccine: a pooled post-hoc analysis of two parallel randomized trials. Hum Vaccin Immunother. 2019;15(12):2865\u201372.","journal-title":"Hum Vaccin Immunother"},{"key":"1323_CR33","doi-asserted-by":"publisher","DOI":"10.5888\/pcd22.240539","volume":"22","author":"KB Watson","year":"2025","unstructured":"Watson KB, Wiltz JL, Nhim K, et al. Trends in multiple chronic conditions among US adults, by life stage, behavioral risk factor surveillance system, 2013-2023. Prev Chronic Dis. 2025;22:E15.","journal-title":"Prev Chronic Dis"},{"issue":"4","key":"1323_CR34","first-page":"502","volume":"8","author":"P Ghaswalla","year":"2021","unstructured":"Ghaswalla P, Thompson-Leduc P, Cheng WY, et al. Increased health care resource utilization and costs associated with herpes zoster among patients aged \u226550\u00a0years with chronic obstructive pulmonary disease in the United States. Chronic Obstr Pulm Dis. 2021;8(4):502\u201316.","journal-title":"Chronic Obstr Pulm Dis"},{"issue":"9","key":"1323_CR35","doi-asserted-by":"publisher","first-page":"869","DOI":"10.2165\/00019053-200624090-00005","volume":"24","author":"E Akobundu","year":"2006","unstructured":"Akobundu E, Ju J, Blatt L, Mullins CD. Cost-of-illness studies. Pharmacoeconomics. 2006;24(9):869\u201390.","journal-title":"Pharmacoeconomics"}],"container-title":["Infectious Diseases and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-026-01323-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40121-026-01323-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40121-026-01323-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T12:50:34Z","timestamp":1779972634000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40121-026-01323-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,16]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["1323"],"URL":"https:\/\/doi.org\/10.1007\/s40121-026-01323-6","relation":{},"ISSN":["2193-8229","2193-6382"],"issn-type":[{"value":"2193-8229","type":"print"},{"value":"2193-6382","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,16]]},"assertion":[{"value":"2 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Nurilign Ahmed and Minh Nguyen are employees of GSK; Nurilign Ahmed holds financial equities in GSK. Van M Nguyen, Anh C Pham, Nam H Nguyen, Son T Tran, Nguyen T Tran, Quyen TL Nguyen, Nhan T Nguyen, Thanh D Le, and Huong TT Nguyen and received fees from Hanoi University of Pharmacy, Vietnam, and GSK, for conducting this study and preparing the study report. Doanh H Le declares no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This study was conducted in accordance with the Declaration of Helsinki. Only retrospective data from patient medical records were accessed as part of this study, omitting any identifiable patient data. Ethical approval was therefore not required in five out of six hospitals. Institutional review board approval was obtained from Bach Mai Hospital, in accordance with its regulations (reference number 7329\/BM-HDDD).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}