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All experiments were performed in accordance with relevant guidelines and regulations. The protocols for this study were approved locally at each site. This study was approved by the Medical Ethics Committee of the Affiliated Drum Tower Hospital of Nanjing University Medical School (IRB No. 2020-377-02) and conducted in accordance with the principles of the Declaration of Helsinki.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}