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Cappelleri, Meghan B. Gavaghan, Verna L. Welch, Santiago M.C. Lopez, and Manuela Di Fusco, are employees of Pfizer and may hold stock or stock options of Pfizer. Laura L. Lupton, Rachel Brathwaite, and Xiaowu Sun are employees of CVS Health\n                      \u00ae\n                      Corporation, which received funding from Pfizer in connection with the development of this manuscript and hold stock of CVS Health\n                      \u00ae\n                      Corporation.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted according to the guidelines of the Declaration of Helsinki. The protocol, amendments and informed consent documents were reviewed and approved by the Sterling Institutional Review Board (Sterling IRB), an independent ethics committee based in Atlanta, Georgia, USA (Protocol #C4591034). 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