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The corresponding author, Tobias Tenenbaum, was also the principal investigator, who received an institutional study grant from Sanofi and Qiagen to conduct the study. Christine Hagemann is a Sanofi employee and may have company shares\/stock options. Marta Gil-Pawlak and Christine Ginocchio are Qiagen employees and may have company shares\/stock options. Maria Adams, Vivien Greese, Anissa Paschereit, Tamina Schenck, Julia Kristin Singer, Johannes Paul Paulick, Rafael Paolo Pricoco, Hermann Girschick, Eva Jenz, and Martina Rabe have nothing to disclose.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All parents with children fulfilling the eligibility criteria were approached regarding their willingness to participate in the study. The local Berlin ethics committee of Eth-56\/23 approved the study protocol. This study was performed in accordance with the Helsinki Declaration of 1964 and its later amendments. Informed consent was obtained from all parents or legal guardians. Parents could withdraw consent for participation at any given time.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}