{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:07:16Z","timestamp":1773864436993,"version":"3.50.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770295"],"award-info":[{"award-number":["81770295"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005063","name":"Excellent Young Talents Fund Program of Higher Education Institutions of Anhui Province","doi-asserted-by":"publisher","award":["gxyqZD2018028"],"award-info":[{"award-number":["gxyqZD2018028"]}],"id":[{"id":"10.13039\/501100005063","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pain Ther"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s40122-020-00188-y","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T17:05:52Z","timestamp":1596474352000},"page":"563-571","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Comparison Between Intravenous Nalbuphine and Lidocaine in Reducing Propofol-Induced Injection Pain During Gastroscopy: A Randomized Controlled Trial"],"prefix":"10.1007","volume":"9","author":[{"given":"Jiang","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinjuan","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cuiyu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongqi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1802-1654","authenticated-orcid":false,"given":"Yao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,3]]},"reference":[{"issue":"2","key":"188_CR1","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1213\/00000539-199202000-00014","volume":"74","author":"D Mangar","year":"1992","unstructured":"Mangar D, Holak EJ. Tourniquet at 50 mmHg followed by intravenous lidocaine diminishes hand pain associated with propofol injection. Anesth Analg. 1992;74(2):250\u20132. https:\/\/doi.org\/10.1213\/00000539-199202000-00014.","journal-title":"Anesth Analg"},{"issue":"4","key":"188_CR2","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1097\/00000539-200004000-00035","volume":"90","author":"P Picard","year":"2000","unstructured":"Picard P, Tramer MR. Prevention of pain on injection with propofol: a quantitative systematic review. Anesth Analg. 2000;90(4):963\u20139. https:\/\/doi.org\/10.1097\/00000539-200004000-00035.","journal-title":"Anesth Analg"},{"issue":"1","key":"188_CR3","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1007\/s00540-017-2430-3","volume":"32","author":"X Li","year":"2018","unstructured":"Li X, Chen CJ, Tan F, et al. Effect of dexmedetomidine for attenuation of propofol injection pain in electroconvulsive therapy: a randomized controlled study. J Anesth. 2018;32(1):70\u20136. https:\/\/doi.org\/10.1007\/s00540-017-2430-3.","journal-title":"J Anesth"},{"key":"188_CR4","doi-asserted-by":"publisher","first-page":"CD007874","DOI":"10.1002\/14651858.CD007874.pub2","volume":"2","author":"P Euasobhon","year":"2016","unstructured":"Euasobhon P, Dej-Arkom S, Siriussawakul A, et al. Lidocaine for reducing propofol-induced pain on induction of anaesthesia in adults. Cochrane Database Syst Rev. 2016;2:CD007874. https:\/\/doi.org\/10.1002\/14651858.CD007874.pub2.","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"188_CR5","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1046\/j.1365-2044.2002.02602.x","volume":"57","author":"AF Davies","year":"2002","unstructured":"Davies AF, Vadodaria B, Hopwood B, Dexter T, Conn D. Efficacy of microfiltration in decreasing propofol-induced pain. Anaesthesia. 2002;57(6):557\u201361. https:\/\/doi.org\/10.1046\/j.1365-2044.2002.02602.x.","journal-title":"Anaesthesia"},{"issue":"1","key":"188_CR6","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1097\/AJP.0000000000000211","volume":"32","author":"RG Jannuzzi","year":"2016","unstructured":"Jannuzzi RG. Nalbuphine for treatment of opioid-induced pruritus: a systematic review of literature. Clin J Pain. 2016;32(1):87\u201393. https:\/\/doi.org\/10.1097\/AJP.0000000000000211.","journal-title":"Clin J Pain"},{"issue":"1","key":"188_CR7","doi-asserted-by":"publisher","first-page":"119","DOI":"10.4103\/aer.AER_188_18","volume":"13","author":"M Bisht","year":"2019","unstructured":"Bisht M, Pokhriyal AS, Khurana G, Sharma JP. Effect of fentanyl and nalbuphine for prevention of etomidate-induced myoclonus. Anesth Essays Res. 2019;13(1):119\u201325. https:\/\/doi.org\/10.4103\/aer.AER_188_18.","journal-title":"Anesth Essays Res"},{"issue":"6","key":"188_CR8","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1093\/bja\/aem293","volume":"99","author":"JR Lee","year":"2007","unstructured":"Lee JR, Jung CW, Lee YH. Reduction of pain during induction with target-controlled propofol and remifentanil. Br J Anaesth. 2007;99(6):876\u201380. https:\/\/doi.org\/10.1093\/bja\/aem293.","journal-title":"Br J Anaesth"},{"issue":"9","key":"188_CR9","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1017\/S026502150600233X","volume":"24","author":"K Kwak","year":"2007","unstructured":"Kwak K, Kim J, Park S, et al. Reduction of pain on injection of propofol: combination of pretreatment of remifentanil and premixture of lidocaine with propofol. Eur J Anaesthesiol. 2007;24(9):746\u201350. https:\/\/doi.org\/10.1017\/S026502150600233X.","journal-title":"Eur J Anaesthesiol"},{"issue":"2","key":"188_CR10","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1007\/s00540-014-1892-9","volume":"29","author":"RE Galgon","year":"2015","unstructured":"Galgon RE, Strube P, Heier J, Groth J, Wang S, Schroeder KM. Magnesium sulfate with lidocaine for preventing propofol injection pain: a randomized, double-blind, placebo-controlled trial. J Anesth. 2015;29(2):206\u201311. https:\/\/doi.org\/10.1007\/s00540-014-1892-9.","journal-title":"J Anesth"},{"issue":"2","key":"188_CR11","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1093\/bja\/77.2.162","volume":"77","author":"IJ Wrench","year":"1996","unstructured":"Wrench IJ, Girling KJ, Hobbs GJ. Alfentanil-mediated analgesia during propofol injection: no evidence for a peripheral action. Br J Anaesth. 1996;77(2):162\u20134. https:\/\/doi.org\/10.1093\/bja\/77.2.162.","journal-title":"Br J Anaesth"},{"issue":"4","key":"188_CR12","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.jclinane.2010.09.008","volume":"23","author":"AE Salman","year":"2011","unstructured":"Salman AE, Salman MA, Saricaoglu F, Akinci SB, Aypar U. Pain on injection of propofol: a comparison of methylene blue and lidocaine. J Clin Anesth. 2011;23(4):270\u20134. https:\/\/doi.org\/10.1016\/j.jclinane.2010.09.008.","journal-title":"J Clin Anesth"},{"issue":"6","key":"188_CR13","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1111\/j.1365-2044.1988.tb06641.x","volume":"43","author":"RP Scott","year":"1988","unstructured":"Scott RP, Saunders DA, Norman J. Propofol: clinical strategies for preventing the pain of injection. Anaesthesia. 1988;43(6):492\u20134. https:\/\/doi.org\/10.1111\/j.1365-2044.1988.tb06641.x.","journal-title":"Anaesthesia"},{"issue":"11","key":"188_CR14","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1093\/bja\/53.11.1197","volume":"53","author":"LP Briggs","year":"1981","unstructured":"Briggs LP, Clarke RS, Dundee JW, Moore J, Bahar M, Wright PJ. Use of di-isopropyl phenol as main agent for short procedures. Br J Anaesth. 1981;53(11):1197\u2013202.","journal-title":"Br J Anaesth"},{"issue":"11","key":"188_CR15","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1111\/j.1365-2044.1985.tb10615.x","volume":"40","author":"MJ McCulloch","year":"1985","unstructured":"McCulloch MJ, Lees NW. Assessment and modification of pain on induction with propofol (Diprivan). Anaesthesia. 1985;40(11):1117\u201320. https:\/\/doi.org\/10.1111\/j.1365-2044.1985.tb10615.x.","journal-title":"Anaesthesia"},{"issue":"2","key":"188_CR16","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1093\/bja\/66.2.189","volume":"66","author":"W Klement","year":"1991","unstructured":"Klement W, Arndt JO. Pain on iv injection of some anaesthetic agents is evoked by the unphysiological osmolality or pH of their formulations. Br J Anaesth. 1991;66(2):189\u201395. https:\/\/doi.org\/10.1093\/bja\/66.2.189.","journal-title":"Br J Anaesth"},{"issue":"1","key":"188_CR17","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1590\/s0034-70942007000100004","volume":"57","author":"KM El-Radaideh","year":"2007","unstructured":"El-Radaideh KM. Effect of pretreatment with lidocaine, intravenous paracetamol and lidocaine-fentanyl on propofol injection pain. Comparative study. Rev Bras Anestesiol. 2007;57(1):32\u20138. https:\/\/doi.org\/10.1590\/s0034-70942007000100004.","journal-title":"Rev Bras Anestesiol"},{"issue":"5","key":"188_CR18","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1007\/BF03016541","volume":"52","author":"A Turan","year":"2005","unstructured":"Turan A, Memis D, Kaya G, Karamanlioglu B. The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine. Can J Anaesth. 2005;52(5):548\u20139. https:\/\/doi.org\/10.1007\/BF03016541.","journal-title":"Can J Anaesth"},{"issue":"1","key":"188_CR19","doi-asserted-by":"publisher","first-page":"27","DOI":"10.2165\/00044011-200828010-00004","volume":"28","author":"A Honarmand","year":"2008","unstructured":"Honarmand A, Safavi M. Prevention of propofol-induced injection pain by sufentanil: a placebo-controlled comparison with remifentanil. Clin Drug Investig. 2008;28(1):27\u201335. https:\/\/doi.org\/10.2165\/00044011-200828010-00004.","journal-title":"Clin Drug Investig"},{"issue":"2","key":"188_CR20","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1046\/j.1365-2044.2003.02964_2.x","volume":"58","author":"KD Roehm","year":"2003","unstructured":"Roehm KD, Piper SN, Maleck WH, Boldt J. Prevention of propofol-induced injection pain by remifentanil: a placebo-controlled comparison with lidocaine. Anaesthesia. 2003;58(2):165\u201370. https:\/\/doi.org\/10.1046\/j.1365-2044.2003.02964_2.x.","journal-title":"Anaesthesia"},{"issue":"5","key":"188_CR21","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1046\/j.1365-2044.1998.00405.x","volume":"53","author":"CH Tan","year":"1998","unstructured":"Tan CH, Onsiong MK. Pain on injection of propofol. Anaesthesia. 1998;53(5):468\u201376. https:\/\/doi.org\/10.1046\/j.1365-2044.1998.00405.x.","journal-title":"Anaesthesia"},{"issue":"1","key":"188_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0014-2999(82)90389-2","volume":"86","author":"C Schmauss","year":"1982","unstructured":"Schmauss C, Doherty C, Yaksh TL. The analgetic effects of an intrathecally administered partial opiate agonist, nalbuphine hydrochloride. Eur J Pharmacol. 1982;86(1):1\u20137. https:\/\/doi.org\/10.1016\/0014-2999(82)90389-2.","journal-title":"Eur J Pharmacol"}],"container-title":["Pain and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40122-020-00188-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40122-020-00188-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40122-020-00188-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T23:45:41Z","timestamp":1627947941000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40122-020-00188-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["188"],"URL":"https:\/\/doi.org\/10.1007\/s40122-020-00188-y","relation":{},"ISSN":["2193-8237","2193-651X"],"issn-type":[{"value":"2193-8237","type":"print"},{"value":"2193-651X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,3]]},"assertion":[{"value":"2 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}