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Zuqui Ram\u00edrez, Victor M. Belalcazar L\u00f3pez, Adelfia Urenda Quezada y Alejandro Gonz\u00e1lez Rebatu y Gonz\u00e1lez have no conflicts of interest to report. Jorge Gonz\u00e1lez Canudas, Jos\u00e9 G. Sander Padilla, Laura A. Lugo S\u00e1nchez, Ileana C. Rodr\u00edguez V\u00e1zquez, Kevin F. Rios Brito, Mar\u00eda M. Arguedas N\u00fa\u00f1ez and Emmanuel Canales V\u00e1zquez report no conflicts of interest in this work. Jorge Gonz\u00e1lez Canudas, Jos\u00e9 G. Sander Padilla, Laura A. Lugo S\u00e1nchez, Ileana C. Rodr\u00edguez V\u00e1zquez, Kevin F. Rios Brito, Mar\u00eda M. Arguedas N\u00fa\u00f1ez and Emmanuel Canales V\u00e1zquez are employees of Laboratorios Silanes.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The present study was developed, until its conclusion, following the legal provisions of the General Health Law of the United Mexican States, the Official Mexican Law NOM-012-SSA3-current version, to the Official Mexican Law NOM-220-SSA1-current version, and in accordance with the Helsinki Declaration of 1964 and its later amendments. The study protocol, informed consent form (ICF), and any other relevant documents according to National Regulation were reviewed and approved by an independent ethics committee (IECs) (Research Committee of Investigaci\u00f3n Biom\u00e9dica para el Desarrollo de F\u00e1rmacos, S.A. de C.V.) with the approval Number: CEI-000002, and the Health Authority (Federal Commission for the Protection against Sanitary Risks [COFEPRIS]) with the <i>approval Number: 213300410A0125\/2021<\/i>. All patients included in this study provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}