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Atsushi Okawa and Toshitaka Yoshii received lecture fees from Daiichi Sankyo Co., Ltd. Hiroshi Takahashi and Kazuhito Shiosakai are employees of Daiichi Sankyo Co., Ltd.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study was approved by Tokyo Medical and Dental University Certified Review Board (current name, Institution of Science Tokyo) (CRB No. 3240003). The study was conducted in accordance with the Clinical Research Act in Japan, and the ethical principles, clinical research laws, and relevant notifications stipulated in the Declaration of Helsinki (as revised in 2013). This study was registered in the Japan Registry of Clinical Trials under the identifier jRCTs031210629. All patients provided informed consent to participate in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}