{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:02:11Z","timestamp":1792872131224,"version":"4.5.0"},"reference-count":78,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100002418","name":"Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College","doi-asserted-by":"publisher","award":["2024ZL1291"],"award-info":[{"award-number":["2024ZL1291"]}],"id":[{"id":"10.13039\/501100002418","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017594","name":"Medical Science and Technology Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2024KY564"],"award-info":[{"award-number":["2024KY564"]}],"id":[{"id":"10.13039\/501100017594","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Lishui Science and Technology Plan Project","award":["2022SJZC020"],"award-info":[{"award-number":["2022SJZC020"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pain Ther"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1007\/s40122-025-00796-6","type":"journal-article","created":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T06:26:32Z","timestamp":1765088792000},"page":"269-289","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prediction of Postherpetic Neuralgia in Patients with Acute and Subacute Herpetic Neuralgia Using Structural Magnetic Resonance Imaging: A Retrospective Study"],"prefix":"10.1007","volume":"15","author":[{"given":"Dan","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjie","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wujun","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junlin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyi","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoyin","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubo","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanguang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yakang","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiansong","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8640-4600","authenticated-orcid":false,"given":"Zhongwei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,7]]},"reference":[{"issue":"1","key":"796_CR1","doi-asserted-by":"publisher","first-page":"15016","DOI":"10.1038\/nrdp.2015.16","volume":"1","author":"AA Gershon","year":"2015","unstructured":"Gershon AA, Breuer J, Cohen JI, Cohrs RJ, Gershon MD, Gilden D, et al. Varicella zoster virus infection. Nat Rev Dis Prim. 2015;1(1):15016.","journal-title":"Nat Rev Dis Prim"},{"issue":"1","key":"796_CR2","doi-asserted-by":"publisher","first-page":"2344983","DOI":"10.1080\/21645515.2024.2344983","volume":"20","author":"J Chen","year":"2024","unstructured":"Chen J, Abrahamson PE, Ke Y, Ong CR, Parikh R, Shantakumar S. A systematic literature review of the epidemiology and burden of herpes zoster in selected locales in Asia Pacific. Hum Vaccin Immunother. 2024;20(1):2344983.","journal-title":"Hum Vaccin Immunother"},{"issue":"2","key":"796_CR3","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1080\/21645515.2017.1264831","volume":"13","author":"G Gabutti","year":"2017","unstructured":"Gabutti G, Bonanni P, Conversano M, Fanelli G, Franco E, Greco D, et al. Prevention of herpes zoster and its complications: from clinical evidence to real life experience. Hum Vaccin Immunother. 2017;13(2):391\u20138.","journal-title":"Hum Vaccin Immunother"},{"issue":"4","key":"796_CR4","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1177\/2051013615599151","volume":"3","author":"RW Johnson","year":"2015","unstructured":"Johnson RW, Alvarez-Pasquin MJ, Bijl M, Franco E, Gaillat J, Clara JG, et al. Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective. Ther Adv Vaccines. 2015;3(4):109\u201320.","journal-title":"Ther Adv Vaccines"},{"key":"796_CR5","first-page":"861","volume":"5","author":"M Tontodonati","year":"2012","unstructured":"Tontodonati M, Ursini T, Polilli E, Vadini F, Di Masi F, Volpone D, et al. Postherpetic neuralgia. Int J Gen Med. 2012;5:861\u201371.","journal-title":"Int J Gen Med."},{"issue":"2","key":"796_CR6","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1007\/s40122-020-00196-y","volume":"9","author":"XX Wang","year":"2020","unstructured":"Wang XX, Zhang Y, Fan BF. Predicting postherpetic neuralgia in patients with herpes zoster by machine learning: a retrospective study. Pain Ther. 2020;9(2):627\u201335.","journal-title":"Pain Ther"},{"key":"796_CR7","unstructured":"United Nations Economic and Social Commission for Asia and the Pacific. Addressing the challenges of population ageing in Asia and the Pacific. 2017. https:\/\/www.unescap.org\/sites\/default\/files\/publications\/Addressing%20the%20Challenges%20of%20Population%20Ageing%20in%20Asia%20and%20the%20Pacific.pdf. Accessed Nov 2023."},{"issue":"1","key":"796_CR8","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s40520-018-0968-z","volume":"31","author":"S Cocchio","year":"2019","unstructured":"Cocchio S, Baldovin T, Furlan P, Bertoncello C, Buja A, Saia M, et al. Cross-sectional study on hospitalizations related to herpes zoster in an Italian region, 2008\u20132016. Aging Clin Exp Res. 2019;31(1):145\u201350.","journal-title":"Aging Clin Exp Res"},{"issue":"15","key":"796_CR9","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1186\/s12889-015-1514-y","volume":"27","author":"A Gater","year":"2015","unstructured":"Gater A, Uhart M, McCool R, Pr\u00e9aud E. The humanistic, economic and societal burden of herpes zoster in Europe: a critical review. BMC Public Health. 2015;27(15):193.","journal-title":"BMC Public Health"},{"issue":"4","key":"796_CR10","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/s40801-017-0119-4","volume":"4","author":"H Nakamura","year":"2017","unstructured":"Nakamura H, Mizukami A, Adachi K, Matthews S, Holl K, Asano K, et al. Economic burden of Herpes zoster and post-herpetic neuralgia in adults 60 years of age or older: results from a prospective, physician practice-based cohort study in Kushiro, Japan. Drugs Real World Outcomes. 2017;4(4):187\u201398.","journal-title":"Drugs Real World Outcomes"},{"key":"796_CR11","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/0304-3959(91)90124-G","volume":"44","author":"CPN Watson","year":"1991","unstructured":"Watson CPN, Deck JH, Morshead C, Van der Kooy D, Evans RJ. Postherpetic neuralgia: further post-mortem studies of cases with and without pain. Pain. 1991;44:105\u201317.","journal-title":"Pain"},{"issue":"3","key":"796_CR12","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1006\/nbdi.1996.0021","volume":"3","author":"MC Rowbotham","year":"1996","unstructured":"Rowbotham MC, Yosipovitch G, Connolly MK, et al. Cutaneous innervation density in the allodynic form of postherpetic neuralgia. Neurobiol Dis. 1996;3(3):205\u201314.","journal-title":"Neurobiol Dis"},{"issue":"3","key":"796_CR13","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1097\/j.pain.0000000000001122","volume":"159","author":"M Fetell","year":"2018","unstructured":"Fetell M, Sendel M, Li T, Marinelli L, Vollert J, Ruggerio E, et al. Inflammation in the pathophysiology of neuropathic pain. Pain. 2018;159(3):595\u2013602.","journal-title":"Pain"},{"issue":"8","key":"796_CR14","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13867","volume":"30","author":"Q Liu","year":"2024","unstructured":"Liu Q, Han J, Zhang X. Peripheral and central pathogenesis of postherpetic neuralgia. Skin Res Technol. 2024;30(8):e13867.","journal-title":"Skin Res Technol"},{"issue":"11","key":"796_CR15","doi-asserted-by":"publisher","first-page":"2435","DOI":"10.1097\/j.pain.0000000000002950","volume":"164","author":"FL Rice","year":"2023","unstructured":"Rice FL, Baron R. Cutaneous nerve fiber and peripheral Nav1.7 assessment in a large cohort of patients with postherpetic neuralgia. Pain. 2023;164(11):2435\u201346.","journal-title":"Pain"},{"issue":"4","key":"796_CR16","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1016\/j.nurt.2009.07.005","volume":"6","author":"A Delaney","year":"2009","unstructured":"Delaney A, Colvin LA, Fallon MT, Dalziel RG, Mitchell R, Fleetwood-Walker SM. Postherpetic neuralgia: from preclinical models to the clinic. Neurotherapeutics. 2009;6(4):630.","journal-title":"Neurotherapeutics"},{"key":"796_CR17","doi-asserted-by":"publisher","first-page":"4306","DOI":"10.1016\/j.febslet.2006.06.087","volume":"580","author":"SA Owolabi","year":"2006","unstructured":"Owolabi SA, Saab CY. Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn. FEBS Lett. 2006;580:4306\u201310.","journal-title":"FEBS Lett"},{"key":"796_CR18","doi-asserted-by":"publisher","first-page":"7317","DOI":"10.1523\/JNEUROSCI.1526-05.2005","volume":"25","author":"J Scholz","year":"2005","unstructured":"Scholz J, Broom DC, Youn DH, et al. Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury. J Neurosci. 2005;25:7317\u201323.","journal-title":"J Neurosci"},{"key":"796_CR19","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1002\/glia.23571","volume":"67","author":"QQ Yang","year":"2019","unstructured":"Yang QQ, Zhou JW. Neuroinflammation in the central nervous system: symphony of glial cells. Glia. 2019;67:1017\u201335.","journal-title":"Glia"},{"issue":"11","key":"796_CR20","doi-asserted-by":"publisher","first-page":"2137","DOI":"10.1097\/j.pain.0000000000001014","volume":"158","author":"A Bittar","year":"2017","unstructured":"Bittar A, Jun J, La JH, Wang J, Leem JW, Chung JM. Reactive oxygen species affect spinal cell type-specific synaptic plasticity in a model of neuropathic pain. Pain. 2017;158(11):2137\u201346.","journal-title":"Pain"},{"issue":"377","key":"796_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2023.578068","volume":"15","author":"JL Sun","year":"2023","unstructured":"Sun JL, Dai WJ, Shen XY, L\u00fc N, Zhang YQ. Interleukin-17 is involved in neuropathic pain and spinal synapse plasticity on mice. J Neuroimmunol. 2023;15(377):578068.","journal-title":"J Neuroimmunol"},{"key":"796_CR22","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.neuroimage.2013.02.029","volume":"74","author":"M Obermann","year":"2013","unstructured":"Obermann M, Rodriguez-Raecke R, Naegel S, et al. Gray matter volume reduction reflects chronic pain in trigeminal neuralgia. Neuroimage. 2013;74:352\u20138.","journal-title":"Neuroimage"},{"issue":"1752","key":"796_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2020.147219","volume":"1","author":"Y Tang","year":"2021","unstructured":"Tang Y, Wang M, Zheng T, Xiao Y, Wang S, Han F, et al. Structural and functional brain abnormalities in postherpetic neuralgia: a systematic review of neuroimaging studies. Brain Res. 2021;1(1752):147219.","journal-title":"Brain Res"},{"issue":"7","key":"796_CR24","doi-asserted-by":"publisher","first-page":"605","DOI":"10.2147\/JPR.S183561","volume":"12","author":"J Liu","year":"2019","unstructured":"Liu J, Gu L, Huang Q, Hong S, Zeng X, Zhang D, et al. Altered gray matter volume in patients with herpes zoster and postherpetic neuralgia. J Pain Res. 2019;12(7):605\u201316.","journal-title":"J Pain Res"},{"issue":"1","key":"796_CR25","first-page":"184","volume":"10","author":"S Cao","year":"2018","unstructured":"Cao S, Qin B, Zhang Y, Yuan J, Fu B, Xie P, et al. Herpes zoster chronification to postherpetic neuralgia induces brain activity and grey matter volume change. Am J Transl Res. 2018;10(1):184\u201399.","journal-title":"Am J Transl Res"},{"issue":"1769","key":"796_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2021.147608","volume":"15","author":"Y Tang","year":"2021","unstructured":"Tang Y, Ren C, Wang M, Dai G, Xiao Y, Wang S, et al. Altered gray matter volume and functional connectivity in patients with herpes zoster and postherpetic neuralgia. Brain Res. 2021;15(1769):147608.","journal-title":"Brain Res"},{"issue":"11","key":"796_CR27","doi-asserted-by":"publisher","first-page":"1750","DOI":"10.1093\/infdis\/jiy095","volume":"217","author":"AL Cunningham","year":"2018","unstructured":"Cunningham AL, Heineman TC, Lal H, Godeaux O, Chlibek R, Hwang SJ, et al. Immune responses to a recombinant glycoprotein e herpes zoster vaccine in adults aged 50 years or older. J Infect Dis. 2018;217(11):1750\u201360.","journal-title":"J Infect Dis"},{"issue":"7","key":"796_CR28","doi-asserted-by":"publisher","first-page":"2050","DOI":"10.1080\/21645515.2020.1859321","volume":"17","author":"JH Kim","year":"2021","unstructured":"Kim JH, Diaz-Decaro J, Jiang N, Hwang SJ, Choo EJ, Co M, et al. The adjuvanted recombinant zoster vaccine is efficacious and safe in Asian adults \u2265 50 years of age: a sub-cohort analysis of the ZOE-50 and ZOE-70 randomized trials. Hum Vaccin Immunother. 2021;17(7):2050\u20137.","journal-title":"Hum Vaccin Immunother"},{"issue":"48","key":"796_CR29","doi-asserted-by":"publisher","first-page":"7244","DOI":"10.1016\/j.vaccine.2023.10.049","volume":"41","author":"G Di Giuseppe","year":"2023","unstructured":"Di Giuseppe G, Pelullo CP, Napoli A, Napolitano F. Willingness to receive Herpes Zoster vaccination among adults and older people: a cross sectional study in Italy. Vaccine. 2023;41(48):7244\u20139.","journal-title":"Vaccine"},{"issue":"12","key":"796_CR30","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.3390\/vaccines12121393","volume":"12","author":"J Grudzi\u0105\u017c-S\u0119kowska","year":"2024","unstructured":"Grudzi\u0105\u017c-S\u0119kowska J, S\u0119kowski K, Grze\u015bczyk-Nojszewska Z, Kami\u0144ska A, Sierpi\u0144ski R, Ostrowski J, et al. Public awareness and willingness to vaccinate against herpes zoster: a nationwide cross-sectional study in Poland. Vaccines (Basel). 2024;12(12):1393.","journal-title":"Vaccines (Basel)"},{"issue":"4","key":"796_CR31","first-page":"E543","volume":"25","author":"L Min","year":"2022","unstructured":"Min L, Han H, ShengXiong T, et al. The therapeutic efficacy of pulsed radiofrequency alone versus a dexamethasone and pulsed radiofrequency combination in patients with trigeminal postherpetic neuralgia: a double-blind, randomized controlled trial. Pain Physician. 2022;25(4):E543\u20139.","journal-title":"Pain Physician"},{"issue":"3","key":"796_CR32","doi-asserted-by":"publisher","first-page":"E155","DOI":"10.36076\/ppj.2023.26.E155","volume":"26","author":"CL Sun","year":"2023","unstructured":"Sun CL, Li XL, Li CW, He N, Zhang J, Xue FS. High-voltage, long-duration pulsed radiofrequency to the dorsal root ganglion provides improved pain relief for herpes zoster neuralgia in the subacute stage. Pain Physician. 2023;26(3):E155\u201362.","journal-title":"Pain Physician"},{"issue":"9","key":"796_CR33","first-page":"543","volume":"3","author":"KJ Friesen","year":"2016","unstructured":"Friesen KJ, Falk J, Alessi-Severini S, Chateau D, Bugden S. Price of pain: population-based cohort burden of disease analysis of medication cost of herpes zoster and postherpetic neuralgia. J Pain Res. 2016;3(9):543\u201350.","journal-title":"J Pain Res"},{"issue":"4","key":"796_CR34","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1007\/s40122-024-00612-7","volume":"13","author":"Z Lin","year":"2024","unstructured":"Lin Z, Yu LY, Pan SY, Cao Y, Lin P. Development of a prediction model and corresponding scoring table for postherpetic neuralgia using six machine learning algorithms: a retrospective study. Pain Ther. 2024;13(4):883\u2013907.","journal-title":"Pain Ther"},{"issue":"17","key":"796_CR35","doi-asserted-by":"publisher","first-page":"3935","DOI":"10.2147\/JPR.S483531","volume":"20","author":"C Wang","year":"2024","unstructured":"Wang C, Song X, Liu J, Song Y, Gao J. Analysis of risk factors and development and validation of a dynamic nomogram for postherpetic neuralgia: a retrospective study. J Pain Res. 2024;20(17):3935\u201348.","journal-title":"J Pain Res"},{"issue":"17","key":"796_CR36","doi-asserted-by":"publisher","first-page":"2299","DOI":"10.2147\/JPR.S466939","volume":"1","author":"M Cai","year":"2024","unstructured":"Cai M, Yin J, Zeng Y, Liu H, Jin Y. A prognostic model incorporating relevant peripheral blood inflammation indicator to predict postherpetic neuralgia in patients with acute herpes zoster. J Pain Res. 2024;1(17):2299\u2013309.","journal-title":"J Pain Res"},{"issue":"15","key":"796_CR37","doi-asserted-by":"publisher","first-page":"1009677","DOI":"10.3389\/fnmol.2022.1009677","volume":"6","author":"R Zhou","year":"2022","unstructured":"Zhou R, Li J, Zhang Y, Xiao H, Zuo Y, Ye L. Characterization of plasma metabolites and proteins in patients with herpetic neuralgia and development of machine learning predictive models based on metabolomic profiling. Front Mol Neurosci. 2022;6(15):1009677.","journal-title":"Front Mol Neurosci"},{"issue":"1","key":"796_CR38","doi-asserted-by":"publisher","first-page":"14940","DOI":"10.1038\/s41598-023-42363-z","volume":"13","author":"L Lu","year":"2023","unstructured":"Lu L, Mei L, Li X, Lin Y, Wang H, Yang G. Metabolomics profiling in predicting of post-herpetic neuralgia induced by varicella zoster. Sci Rep. 2023;13(1):14940.","journal-title":"Sci Rep"},{"key":"796_CR39","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1038\/s44220-022-00007-7","volume":"1","author":"M Gao","year":"2023","unstructured":"Gao M, Wong NML, Lin C, et al. Multimodal brain connectome-based prediction of suicide risk in people with late-life depression. Natl Ment Health. 2023;1:100\u201313.","journal-title":"Natl Ment Health"},{"issue":"16","key":"796_CR40","doi-asserted-by":"publisher","first-page":"1364808","DOI":"10.3389\/fnagi.2024.1364808","volume":"5","author":"Z Li","year":"2024","unstructured":"Li Z, Wu M, Yin C, Wang Z, Wang J, Chen L, et al. Machine learning based on the EEG and structural MRI can predict different stages of vascular cognitive impairment. Front Aging Neurosci. 2024;5(16):1364808.","journal-title":"Front Aging Neurosci"},{"key":"796_CR41","doi-asserted-by":"publisher","first-page":"401","DOI":"10.3414\/ME17-01-0051","volume":"56","author":"N Brusselaers","year":"2017","unstructured":"Brusselaers N, Lagergren J. The charlson comorbidity index in registry-based research. Methods Inf Med. 2017;56:401\u20136.","journal-title":"Methods Inf Med"},{"key":"796_CR42","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.neulet.2017.04.034","volume":"651","author":"B Peng","year":"2017","unstructured":"Peng B, Wang S, Zhou Z, Liu Y, Tong B, Zhang T, et al. A multilevel-ROI features-based machine learning method for detection of morphometric biomarkers in Parkinson\u2019s disease. Neurosci Lett. 2017;651:88\u201394.","journal-title":"Neurosci Lett"},{"key":"796_CR43","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1006\/nimg.2001.0978","volume":"15","author":"N Tzourio-Mazoyer","year":"2002","unstructured":"Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002;15:273\u201389.","journal-title":"Neuroimage"},{"issue":"3","key":"796_CR44","first-page":"E481","volume":"25","author":"J Zhang","year":"2022","unstructured":"Zhang J, Ding Q, Li XL, Hao YW, Yang Y. Support vector machine versus multiple logistic regression for prediction of postherpetic neuralgia in outpatients with herpes zoster. Pain Physician. 2022;25(3):E481\u20138.","journal-title":"Pain Physician"},{"issue":"10","key":"796_CR45","doi-asserted-by":"publisher","first-page":"8123","DOI":"10.1007\/s12035-024-04073-z","volume":"61","author":"S Han","year":"2024","unstructured":"Han S, Wang J, Zhang W, Tian X. Chronic pain-related cognitive deficits: preclinical insights into molecular, cellular, and circuit mechanisms. Mol Neurobiol. 2024;61(10):8123\u201343.","journal-title":"Mol Neurobiol"},{"key":"796_CR46","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1097\/j.pain.0000000000001519","volume":"160","author":"LJ Ayoub","year":"2019","unstructured":"Ayoub LJ, Barnett A, Leboucher A, Golosky M, McAndrews MP, Seminowicz DA, et al. The medial temporal lobe in nociception: a meta-analytic and functional connectivity study. Pain. 2019;160:1245\u201360.","journal-title":"Pain"},{"key":"796_CR47","doi-asserted-by":"publisher","first-page":"3967","DOI":"10.1111\/ejn.15687","volume":"56","author":"U Bingel","year":"2022","unstructured":"Bingel U, Wiech K, Ritter C, Wanigasekera V, Ni Mhuircheartaigh R, Lee MC, et al. Hippocampus mediates nocebo impairment of opioid analgesia through changes in functional connectivity. Eur J Neurosci. 2022;56:3967\u201378.","journal-title":"Eur J Neurosci"},{"key":"796_CR48","doi-asserted-by":"publisher","first-page":"9896","DOI":"10.1523\/JNEUROSCI.21-24-09896.2001","volume":"21","author":"A Ploghaus","year":"2001","unstructured":"Ploghaus A, Narain C, Beckmann CF, Clare S, Bantick S, Wise R, et al. Exacerbation of pain by anxiety is associated with activity in a hippocampal network. J Neurosci. 2001;21:9896\u2013903.","journal-title":"J Neurosci"},{"issue":"9","key":"796_CR49","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.1097\/j.pain.0000000000003221","volume":"165","author":"LJ Ayoub","year":"2024","unstructured":"Ayoub LJ, Honigman L, Barnett AJ, McAndrews MP, Moayedi M. Mechanical pain sensitivity is associated with hippocampal structural integrity. Pain. 2024;165(9):2079\u201386.","journal-title":"Pain"},{"issue":"5","key":"796_CR50","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1097\/j.pain.0000000000003100","volume":"165","author":"S Han","year":"2024","unstructured":"Han S, Ren J, Li Z, Wen J, Jiang B, Wei X. Deactivation of dorsal CA1 pyramidal neurons projecting to medial prefrontal cortex contributes to neuropathic pain and short-term memory impairment. Pain. 2024;165(5):1044\u201359.","journal-title":"Pain"},{"issue":"1","key":"796_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1162\/08989290051137585","volume":"12","author":"R Cabeza","year":"2000","unstructured":"Cabeza R, Nyberg L. Imaging cognition II: an empirical review of 275 PET and fMRI studies. J Cogn Neurosci. 2000;12(1):1\u201347.","journal-title":"J Cogn Neurosci"},{"issue":"3","key":"796_CR52","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/j.neuroimage.2005.04.034","volume":"27","author":"FA Nielsen","year":"2005","unstructured":"Nielsen FA, Balslev D, Hansen LK. Mining the posterior cingulate: segregation between memory and pain components. Neuroimage. 2005;27(3):520\u201332.","journal-title":"Neuroimage"},{"issue":"4","key":"796_CR53","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jpain.2017.02.219","volume":"18","author":"C Becker","year":"2017","unstructured":"Becker C, et al. (326) Posterior cingulate connectivity changes during acute and chronic pain. J Pain. 2017;18(4):56.","journal-title":"J Pain"},{"issue":"8","key":"796_CR54","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1002\/art.40507","volume":"70","author":"J Lee","year":"2018","unstructured":"Lee J, Protsenko E, Lazaridou A, Franceschelli O, Ellingsen DM, Mawla I, et al. Encoding of self-referential pain catastrophizing in the posterior cingulate cortex in fibromyalgia. Arthritis Rheumatol. 2018;70(8):1308\u201318.","journal-title":"Arthritis Rheumatol"},{"key":"796_CR55","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1002\/hbm.22737","volume":"36","author":"J Liu","year":"2015","unstructured":"Liu J, Lan L, Mu J, Zhao L, Yuan K, Zhang Y, et al. Genetic contribution of catechol-O-methyltransferase in hippocampal structural and functional changes of female migraine sufferers. Hum Brain Mapp. 2015;36:1782\u201395.","journal-title":"Hum Brain Mapp"},{"key":"796_CR56","doi-asserted-by":"publisher","first-page":"3960","DOI":"10.1002\/art.24070","volume":"58","author":"J Lutz","year":"2008","unstructured":"Lutz J, Jager L, de Quervain D, Krauseneck T, Padberg F, Wichnalek M, et al. White and gray matter abnormalities in the brain of patients with fibromyalgia: a diffusiontensor and volumetric imaging study. Arthritis Rheum. 2008;58:3960\u20139.","journal-title":"Arthritis Rheum"},{"key":"796_CR57","doi-asserted-by":"publisher","DOI":"10.1186\/1744-8069-6-27","volume":"6","author":"D Borsook","year":"2010","unstructured":"Borsook D, Upadhyay J, Chudler EH, Becerra L. A key role of the basal ganglia in pain and analgesia\u2013insights gained through human functional imaging. Mol Pain. 2010;6:27.","journal-title":"Mol Pain"},{"issue":"3","key":"796_CR58","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1016\/j.neuroimage.2005.10.033","volume":"30","author":"U Baumg\u00e4rtner","year":"2006","unstructured":"Baumg\u00e4rtner U, Buchholz HG, Bellosevich A, Magerl W, Siessmeier T, Rolke R, et al. High opiate receptor binding potential in the human lateral pain system. Neuroimage. 2006;30(3):692\u20139.","journal-title":"Neuroimage"},{"issue":"3","key":"796_CR59","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1097\/j.pain.0000000000001745","volume":"161","author":"M Azqueta-Gavaldon","year":"2020","unstructured":"Azqueta-Gavaldon M, Youssef AM, Storz C, Lemme J, Schulte-Gocking H, Becerra L, et al. Implications of the putamen in pain and motor deficits in complex regional pain syndrome. Pain. 2020;161(3):595\u2013608.","journal-title":"Pain"},{"key":"796_CR60","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.parkreldis.2018.06.024","volume":"55","author":"H Eggink","year":"2018","unstructured":"Eggink H, Szlufik S, Coenen MA, van Egmond ME, Moro E, Tijssen MAJ. Non-motor effects of deep brain stimulation in dystonia: a systematic review. Parkinsonism Relat Disord. 2018;55:26\u201344.","journal-title":"Parkinsonism Relat Disord"},{"issue":"4","key":"796_CR61","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.3171\/2019.7.JNS191050","volume":"133","author":"P De Vloo","year":"2019","unstructured":"De Vloo P, Milosevic L, Gramer RM, Aguirre-Padilla DH, Dallapiazza RF, Lee DJ, et al. Complete resolution of postherpetic neuralgia following pallidotomy: case report. J Neurosurg. 2019;133(4):1229\u201334. https:\/\/doi.org\/10.3171\/2019.7.JNS191050.","journal-title":"J Neurosurg"},{"key":"796_CR62","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1016\/j.neuroscience.2006.02.022","volume":"140","author":"H Leite-Almeida","year":"2006","unstructured":"Leite-Almeida H, Valle-Fernandes A, Almeida A. Brain projections from the medullary dorsal reticular nucleus: an anterograde and retrograde tracing study in the rat. Neuroscience. 2006;140:577\u201395.","journal-title":"Neuroscience"},{"issue":"42","key":"796_CR63","doi-asserted-by":"publisher","first-page":"10789","DOI":"10.1523\/JNEUROSCI.2577-06.2006","volume":"26","author":"DJ Scott","year":"2006","unstructured":"Scott DJ, Heitzeg MM, Koeppe RA, Stohler CS, Zubieta J-K. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. J Neurosci. 2006;26(42):10789\u201395.","journal-title":"J Neurosci"},{"key":"796_CR64","doi-asserted-by":"publisher","first-page":"S29","DOI":"10.1016\/j.pain.2013.09.001","volume":"154","author":"L Garcia-Larrea","year":"2013","unstructured":"Garcia-Larrea L, Peyron R. Pain matrices and neuropathic pain matrices: a review. Pain. 2013;154:S29\u201343.","journal-title":"Pain"},{"issue":"2","key":"796_CR65","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1007\/s12035-018-1130-9","volume":"56","author":"WY Ong","year":"2019","unstructured":"Ong WY, Stohler CS, Herr DR. Role of the prefrontal cortex in pain processing. Mol Neurobiol. 2019;56(2):1137\u201366. https:\/\/doi.org\/10.1007\/s12035-018-1130-9.","journal-title":"Mol Neurobiol"},{"issue":"3","key":"796_CR66","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.pain.2005.11.008","volume":"120","author":"DA Seminowicz","year":"2006","unstructured":"Seminowicz DA, Davis KD. Cortical responses to pain in healthy individuals depends on pain catastrophizing. Pain. 2006;120(3):297\u2013306.","journal-title":"Pain"},{"issue":"1\u20132","key":"796_CR67","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.jns.2015.01.019","volume":"349","author":"G Perlaki","year":"2015","unstructured":"Perlaki G, Orsi G, Schwarcz A, Bodi P, Plozer E, Biczo K, et al. Pain-related autonomic response is modulated by the medial prefrontal cortex: an ECG-fMRI study in men. J Neurol Sci. 2015;349(1\u20132):202\u20138.","journal-title":"J Neurol Sci"},{"issue":"3","key":"796_CR68","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.jpain.2015.12.002","volume":"17","author":"AJ Karmann","year":"2016","unstructured":"Karmann AJ, Maihofner C, Lautenbacher S, Sperling W, Kornhuber J, Kunz M. The role of prefrontal inhibition in regulating facial expressions of pain: a repetitive transcranial magnetic stimulation study. J Pain. 2016;17(3):383\u201391.","journal-title":"J Pain"},{"issue":"5","key":"796_CR69","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1002\/hbm.25310","volume":"42","author":"Y Li","year":"2021","unstructured":"Li Y, Li W, Zhang T, Zhang J, Jin Z, Li L. Probing the role of the right inferior frontal gyrus during pain-related empathy processing: evidence from fMRI and TMS. Hum Brain Mapp. 2021;42(5):1518\u201331.","journal-title":"Hum Brain Mapp"},{"issue":"11","key":"796_CR70","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.2147\/JPR.S166571","volume":"2","author":"J Li","year":"2018","unstructured":"Li J, Huang X, Sang K, Bodner M, Ma K, Dong XW. Modulation of prefrontal connectivity in postherpetic neuralgia patients with chronic pain: a resting-state functional magnetic resonance-imaging study. J Pain Res. 2018;2(11):2131\u201344.","journal-title":"J Pain Res"},{"issue":"13","key":"796_CR71","doi-asserted-by":"publisher","first-page":"534","DOI":"10.3389\/fnins.2019.00534","volume":"28","author":"P Zeng","year":"2019","unstructured":"Zeng P, Huang J, Wu S, Qian C, Chen F, Sun W, et al. Characterizing the structural pattern predicting medication response in herpes zoster patients using multivoxel pattern analysis. Front Neurosci. 2019;28(13):534.","journal-title":"Front Neurosci"},{"key":"796_CR72","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1111\/j.1526-4610.2010.01637.x","volume":"50","author":"T Schmidt-Wilcke","year":"2010","unstructured":"Schmidt-Wilcke T, Hierlmeier S, Leinisch E. Altered regional brain morphology in patients with chronic facial pain. Headache. 2010;50:1278\u201385.","journal-title":"Headache"},{"issue":"Suppl 1","key":"796_CR73","doi-asserted-by":"publisher","first-page":"S109","DOI":"10.1016\/j.pain.2007.05.010","volume":"132","author":"T Schmidt-Wilcke","year":"2007","unstructured":"Schmidt-Wilcke T, Luerding R, Weigand T, Jurgens T, Schuierer G, Leinisch E, et al. Striatal grey matter increase in patients suffering from fibromyalgia\u2014a voxel-based morphometry study. Pain. 2007;132(Suppl 1):S109-116.","journal-title":"Pain"},{"key":"796_CR74","doi-asserted-by":"publisher","first-page":"13746","DOI":"10.1523\/JNEUROSCI.3687-09.2009","volume":"29","author":"R Rodriguez-Raecke","year":"2009","unstructured":"Rodriguez-Raecke R, Niemeier A, Ihle K, Ruether W, May A. Brain gray matter decrease in chronic pain is the consequence and not the cause of pain. J Neurosci. 2009;29:13746\u201350.","journal-title":"J Neurosci"},{"key":"796_CR75","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1002\/nbm.2819","volume":"26","author":"C Jin","year":"2013","unstructured":"Jin C, Yuan K, Zhao L, Zhao L, Yu D, von Deneen KM, et al. Structural and functional abnormalities in migraine patients without aura. NMR Biomed. 2013;26:58\u201364.","journal-title":"NMR Biomed"},{"issue":"7","key":"796_CR76","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1097\/j.pain.0000000000001219","volume":"159","author":"R Ruscheweyh","year":"2018","unstructured":"Ruscheweyh R, Wersching H, Kugel H, Sundermann B, Teuber A. Gray matter correlates of pressure pain thresholds and self-rated pain sensitivity: a voxel-based morphometry study. Pain. 2018;159(7):1359\u201365.","journal-title":"Pain"},{"issue":"13","key":"796_CR77","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynpai.2023.100114","volume":"6","author":"M L\u00f6fgren","year":"2023","unstructured":"L\u00f6fgren M, Sandstr\u00f6m A, Bileviciute-Ljungar I, Mannerkorpi K, Gerdle B, Ernberg M, et al. The effects of a 15-week physical exercise intervention on pain modulation in fibromyalgia: Increased pain-related processing within the cortico-striatal-occipital networks, but no improvement of exercise-induced hypoalgesia. Neurobiol Pain. 2023;6(13):100114.","journal-title":"Neurobiol Pain"},{"issue":"11","key":"796_CR78","doi-asserted-by":"publisher","first-page":"2578","DOI":"10.1016\/j.clinph.2020.07.024","volume":"131","author":"S De Groote","year":"2020","unstructured":"De Groote S, Goudman L, Van Schuerbeek P, Peeters R, Sunaert S, Linderoth B, et al. Effects of spinal cord stimulation on voxel-based brain morphometry in patients with failed back surgery syndrome. Clin Neurophysiol. 2020;131(11):2578\u201387.","journal-title":"Clin Neurophysiol"}],"container-title":["Pain and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40122-025-00796-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40122-025-00796-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40122-025-00796-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T17:02:31Z","timestamp":1768410151000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40122-025-00796-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,7]]},"references-count":78,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["796"],"URL":"https:\/\/doi.org\/10.1007\/s40122-025-00796-6","relation":{},"ISSN":["2193-8237","2193-651X"],"issn-type":[{"value":"2193-8237","type":"print"},{"value":"2193-651X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,7]]},"assertion":[{"value":"5 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dan Wu, Bo Peng, Yingjie Hua, Wujun Geng, Bing Huang, Siyu Lu, Junlin Chen, Keyi He, Yuxi Wang, Qiaoyin Rao, Zubo Jiang, Chuanguang Wang, Yakang Dai, Jiansong Ji, and Zhongwei Zhaohas nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This study was approved by the Ethics Committee of the Fifth Affiliated Hospital of Wenzhou Medical University (reference no. 2025-264-01), and relevant written informed consent was obtained from each participant in accordance with the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}