{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:19:00Z","timestamp":1788347940223,"version":"build-2803163510"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,6,20]],"date-time":"2020-06-20T00:00:00Z","timestamp":1592611200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2020,6,20]],"date-time":"2020-06-20T00:00:00Z","timestamp":1592611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmol Ther"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s40123-020-00272-8","type":"journal-article","created":{"date-parts":[[2020,6,20]],"date-time":"2020-06-20T10:03:02Z","timestamp":1592647382000},"page":"465-483","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["A Contemporary Risk Analysis of Iatrogenic Transmission of Creutzfeldt-Jakob Disease (CJD) via Corneal Transplantation in the United States"],"prefix":"10.1007","volume":"9","author":[{"given":"Tanisha","family":"Martheswaran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan D.","family":"Desautels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1024-6250","authenticated-orcid":false,"given":"Majid","family":"Moshirfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn M.","family":"Shmunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmyne C.","family":"Ronquillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip C.","family":"Hoopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,20]]},"reference":[{"issue":"5","key":"272_CR1","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/eye.1999.198","volume":"13","author":"AM Mcelvanney","year":"1999","unstructured":"Mcelvanney AM, Boodhoo MG. Creutzfeldt-Jakob disease presenting with visual disturbance. Eye. 1999;13(5):693\u20135.","journal-title":"Eye"},{"issue":"1","key":"272_CR2","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1167\/iovs.01-1273","volume":"44","author":"MW Head","year":"2003","unstructured":"Head MW, Northcott V, Rennison K, Ritchie D, Mccardle L, Bunn TJR, et al. Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease. Invest Ophthalmol Vis Sci. 2003;44(1):342.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"272_CR3","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.3201\/eid2310.171142","volume":"23","author":"DJ Lanska","year":"2017","unstructured":"Lanska DJ. Etymologia: Creutzfeldt-Jakob Disease. Emerg Infect Dis 2017; 23(10):1760\u20131761.","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"272_CR4","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1111\/neup.12355","volume":"37","author":"Y Iwasaki","year":"2016","unstructured":"Iwasaki Y. Creutzfeldt-Jakob disease. Neuropathology. 2016;37(2):174\u201388.","journal-title":"Neuropathology"},{"issue":"5","key":"272_CR5","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1111\/j.1440-1789.2009.01023.x","volume":"29","author":"T Hamaguchi","year":"2009","unstructured":"Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Nakamura Y, Sato T, Kitamoto T, et al. The risk of iatrogenic Creutzfeldt-Jakob disease through medical and surgical procedures. Neuropathology. 2009;29(5):625\u201331.","journal-title":"Neuropathology"},{"issue":"10","key":"272_CR6","doi-asserted-by":"publisher","first-page":"1926","DOI":"10.1038\/eye.2008.381","volume":"23","author":"WJ Armitage","year":"2009","unstructured":"Armitage WJ, Tullo AB, Ironside JW. Risk of Creutzfeldt-Jakob disease transmission by ocular surgery and tissue transplantation. Eye. 2009;23(10):1926\u201330.","journal-title":"Eye"},{"issue":"3","key":"272_CR7","first-page":"217","volume":"2","author":"GA Mackay","year":"2011","unstructured":"Mackay GA, Knight RS, Ironside JW. The molecular epidemiology of variant CJD. Int J Mol Epidemiol Genet. 2011;2(3):217\u201327.","journal-title":"Int J Mol Epidemiol Genet"},{"issue":"6","key":"272_CR8","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1212\/WNL.53.6.1197","volume":"53","author":"J Huillard d\u2019Aignaux","year":"1999","unstructured":"Huillard d\u2019Aignaux J, Costagliola D, Maccario J, et al. Incubation period of Creutzfeldt-Jakob disease in human growth hormone recipients in France. Neurology. 1999;53(6):1197\u2013201.","journal-title":"Neurology"},{"issue":"6","key":"272_CR9","doi-asserted-by":"publisher","first-page":"901","DOI":"10.3201\/eid1806.120116","volume":"18","author":"P Brown","year":"2012","unstructured":"Brown P, Brandel JP, Sato T, et al. Iatrogenic Creutzfeldt-Jakob disease, final assessment. Emerg Infect Dis. 2012;18(6):901\u20137.","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"272_CR10","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1001\/archneur.63.2.288","volume":"63","author":"AM Lewis","year":"2006","unstructured":"Lewis AM, Yu M, Dearmond SJ, Dillon WP, et al. Human growth hormone-related iatrogenic Creutzfeldt-Jakob disease with abnormal imaging. Arch Neurol. 2006;63(2):288.","journal-title":"Arch Neurol"},{"issue":"10","key":"272_CR11","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1136\/jnnp-2012-304850","volume":"84","author":"T Hamaguchi","year":"2013","unstructured":"Hamaguchi T, Sakai K, Noguchi-Shinohara M, et al. Insight into the frequent occurrence of dura mater graft-associated Creutzfeldt-Jakob disease in Japan. J Neurol Neurosurg Psychiatry. 2013;84(10):1171\u20135.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"9","key":"272_CR12","doi-asserted-by":"publisher","first-page":"274","DOI":"10.15585\/mmwr.mm6709a3","volume":"67","author":"R Ae","year":"2018","unstructured":"Ae R, Hamaguchi T, Nakamura Y, et al. Update: Dura Mater Graft-Associated Creutzfeldt-Jakob Disease\u2014Japan, 1975\u20132017. MMWR Morb Mortal Wkly Rep. 2018;67(9):274\u20138.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"2","key":"272_CR13","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1097\/NEN.0000000000000033","volume":"73","author":"FO Bastian","year":"2014","unstructured":"Bastian FO. The case for involvement of spiroplasma in the pathogenesis of transmissible spongiform encephalopathies. J Neuropathol Exp Neurol. 2014;73(2):104\u201314.","journal-title":"J Neuropathol Exp Neurol"},{"issue":"5","key":"272_CR14","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1001\/archopht.119.5.721","volume":"119","author":"RH Kennedy","year":"2001","unstructured":"Kennedy RH. Eye banking and screening for Creutzfeldt-Jakob disease. Arch Ophthalmol. 2001;119(5):721.","journal-title":"Arch Ophthalmol"},{"key":"272_CR15","unstructured":"Centers for Disease Control and Prevention. CDC WONDER. https:\/\/wonder.cdc.gov\/."},{"key":"272_CR16","unstructured":"2018 Eye Banking Statistical Report: U.S. Eye Banking Statistics Reported by U.S. Banks. Eye Bank Association of America, Washington, DC, 2019."},{"key":"272_CR17","unstructured":"2019 Eye Banking Statistical Report: U.S. Eye Banking Statistics Reported by U.S. Banks. Eye Bank Association of America, Washington, DC, 2020."},{"issue":"5","key":"272_CR18","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1097\/00003226-200009000-00020","volume":"19","author":"W Chu","year":"2000","unstructured":"Chu W. The past twenty-five years in eye banking. Cornea. 2000;19(5):754\u201365.","journal-title":"Cornea"},{"issue":"7","key":"272_CR19","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1097\/ICO.0b013e31816a628d","volume":"27","author":"RA Maddox","year":"2008","unstructured":"Maddox RA, Belay ED, Curns AT, Zou W-Q, Nowicki S, Lembach RG, et al. Creutzfeldt-Jakob disease in recipients of corneal transplants. Cornea. 2008;27(7):851\u20134.","journal-title":"Cornea"},{"issue":"4","key":"272_CR20","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1001\/archneur.59.4.637","volume":"59","author":"AA Rabinstein","year":"2002","unstructured":"Rabinstein AA, Whiteman ML, Shebert RT. Abnormal diffusion-weighted magnetic resonance imaging in Creutzfeldt-Jakob disease following corneal transplantations. Arch Neurol. 2002;59(4):637\u20139.","journal-title":"Arch Neurol"},{"issue":"4","key":"272_CR21","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1097\/00003226-200405000-00019","volume":"23","author":"KM Hammersmith","year":"2004","unstructured":"Hammersmith KM, Cohen EJ, Rapuano CJ, Laibson PR. Creutzfeldt-Jakob disease following corneal transplantation. Cornea. 2004;23(4):406\u20138.","journal-title":"Cornea"},{"issue":"12","key":"272_CR22","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1056\/NEJM197403212901220","volume":"290","author":"P Duffy","year":"1974","unstructured":"Duffy P, Wolf J, Collins G, DeVoe AG, Streeten B, Cowen D. Letter: Possible person-to-person transmission of Creutzfeldt-Jakob disease. N Engl J Med. 1974;290(12):692\u20133.","journal-title":"N Engl J Med"},{"issue":"7388","key":"272_CR23","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1136\/bmj.326.7388.517\/a","volume":"326","author":"S Mayor","year":"2003","unstructured":"Mayor S. UK government advises tighter measures to reduce risk of CJD transmission during neurosurgery. BMJ. 2003;326(7388):517.","journal-title":"BMJ"},{"issue":"5","key":"272_CR24","doi-asserted-by":"publisher","first-page":"B83","DOI":"10.1053\/j.ajkd.2014.01.274","volume":"63","author":"E Nwadike","year":"2014","unstructured":"Nwadike E, Kannabhiran D, Calderon K, et al. Creutzfeldt-Jakob disease (CJD) in an adult kidney transplant patient. Am J Kidney Dis. 2014;63(5):B83.","journal-title":"Am J Kidney Dis"},{"key":"272_CR25","unstructured":"Department of Health and Human Services (2018). 2018 Profile of Older Americans; 2018 ASI 4004-43"},{"key":"272_CR26","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.ajo.2016.08.005","volume":"170","author":"F Schaub","year":"2016","unstructured":"Schaub F, Enders P, Zachewicz J, et al. Impact of donor age on descemet membrane endothelial keratoplasty outcome: evaluation of donors aged 17\u201355 years. Am J Ophthalmol. 2016;170:119\u201327.","journal-title":"Am J Ophthalmol"},{"issue":"7","key":"272_CR27","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1111\/j.1442-9071.2006.01308.x","volume":"34","author":"A Tullo","year":"2006","unstructured":"Tullo A, Buckley R, Kelly T, Head M, Bennett P, Armitage W, Ironside J. Transplantation of ocular tissue from a donor with sporadic Creutzfeldt-Jakob disease. Clin Exp Ophthalmol. 2006;34(7):645\u20139.","journal-title":"Clin Exp Ophthalmol"},{"issue":"4214","key":"272_CR28","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1126\/science.190.4214.571","volume":"190","author":"EE Manuelidis","year":"1975","unstructured":"Manuelidis EE. Transmission of Creutzfeldt-Jakob disease from man to the guinea pig. Science. 1975;190(4214):571\u20132.","journal-title":"Science"},{"issue":"6","key":"272_CR29","doi-asserted-by":"publisher","first-page":"e02095","DOI":"10.1128\/mBio.02095-18","volume":"9","author":"CD Orr\u00f9","year":"2018","unstructured":"Orr\u00f9 CD, Soldau K, Cordano C, et al. Prion seeds distribute throughout the eyes of sporadic Creutzfeldt-Jakob disease patients. mBio. 2018;9(6):e02095\u2013e2118.","journal-title":"mBio."},{"issue":"1","key":"272_CR30","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.mcn.2005.09.004","volume":"31","author":"R Butowt","year":"2006","unstructured":"Butowt R, Abdelraheim S, Brown DR, Bartheld CSV. Anterograde axonal transport of the exogenous cellular isoform of prion protein in the chick visual system. Mol Cell Neurosci. 2006;31(1):97\u2013108.","journal-title":"Mol Cell Neurosci"},{"issue":"12","key":"272_CR31","doi-asserted-by":"publisher","first-page":"2567","DOI":"10.1002\/jnr.21229","volume":"85","author":"R Butowt","year":"2007","unstructured":"Butowt R, Davies P, Brown DR. Anterograde axonal transport of chicken cellular prion protein (PrPc) in vivo requires its N-terminal part. J Neurosci Res. 2007;85(12):2567\u201379.","journal-title":"J Neurosci Res"},{"key":"272_CR32","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1093\/bmb\/66.1.267","volume":"66","author":"E K\u00fcbler","year":"2003","unstructured":"K\u00fcbler E, Oesch B, Raeber AJ. Diagnosis of prion diseases. Br Med Bull. 2003;66:267\u201379.","journal-title":"Br Med Bull"},{"issue":"4","key":"272_CR33","doi-asserted-by":"publisher","first-page":"e120","DOI":"10.1097\/TP.0000000000001636","volume":"101","author":"L Gregori","year":"2017","unstructured":"Gregori L, Serer AR, McDowell KL, Cervenak J, Asher DM. Rapid testing for Creutzfeldt-Jakob disease in donors of cornea. Transplantation. 2017;101(4):e120\u2013e124124.","journal-title":"Transplantation"},{"issue":"7","key":"272_CR34","doi-asserted-by":"publisher","first-page":"1364","DOI":"10.3201\/eid2407.172105","volume":"24","author":"D Bougard","year":"2018","unstructured":"Bougard D, B\u00e9londrade M, Mayran C, et al. Diagnosis of methionine\/valine variant Creutzfeldt-Jakob disease by protein misfolding cyclic amplification. Emerg Infect Dis. 2018;24(7):1364\u20136.","journal-title":"Emerg Infect Dis"},{"key":"272_CR35","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1097\/00003226-199901000-00002","volume":"18","author":"RN Hogan","year":"1999","unstructured":"Hogan RN, Brown P, Heck E, Cavanagh HD. Risk of prion disease transmission from ocular donor tissue transplantation. Cornea. 1999;18:2\u201311.","journal-title":"Cornea"}],"container-title":["Ophthalmology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-020-00272-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40123-020-00272-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-020-00272-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T10:12:19Z","timestamp":1713348739000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40123-020-00272-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,20]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["272"],"URL":"https:\/\/doi.org\/10.1007\/s40123-020-00272-8","relation":{},"ISSN":["2193-8245","2193-6528"],"issn-type":[{"value":"2193-8245","type":"print"},{"value":"2193-6528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,20]]},"assertion":[{"value":"13 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}