{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T06:06:47Z","timestamp":1792822007591,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Horus Pharma"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmol Ther"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s40123-023-00717-w","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T16:03:33Z","timestamp":1683561813000},"page":"1939-1956","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Keratoconus and the Impact of Treatment on Patients\u2019 Quality of Life: A Qualitative Study"],"prefix":"10.1007","volume":"12","author":[{"given":"Pierre","family":"Fourni\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u00ebl","family":"Acquadro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Touboul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9atrice","family":"Cochener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Chiambaretta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Muraine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Borderie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Bourges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadra","family":"Benmedjahed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9atrice","family":"Tugaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Bernheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan","family":"Bourcier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Burillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"David","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Delbosc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Gain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Hoffart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Labetoulle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Laroche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Malet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Orignac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Yves","family":"Robert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Thuret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Vabres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Malecaze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Arnould","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,8]]},"reference":[{"issue":"4","key":"717_CR1","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1097\/ICO.0000000000000408","volume":"34","author":"JA Gomes","year":"2015","unstructured":"Gomes JA, et\u00a0al. Global consensus on keratoconus and ectatic diseases. Cornea. 2015;34(4):359\u201369.","journal-title":"Cornea"},{"key":"717_CR2","doi-asserted-by":"crossref","unstructured":"Hashemi, H., et\u00a0al. The Prevalence and Risk Factors for Keratoconus: A Systematic Review and Meta-Analysis. Cornea, 2020. Feb;39(2):263\u2013270.","DOI":"10.1097\/ICO.0000000000002150"},{"issue":"4","key":"717_CR3","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/S0886-3350(98)80284-8","volume":"24","author":"JH Krumeich","year":"1998","unstructured":"Krumeich JH, Daniel J, Kn\u00fclle A. Live-epikeratophakia for keratoconus. J Cataract Refract Surg. 1998;24(4):456\u201363.","journal-title":"J Cataract Refract Surg"},{"issue":"6","key":"717_CR4","doi-asserted-by":"publisher","first-page":"539","DOI":"10.3928\/1081-597X-20060601-05","volume":"22","author":"JL Ali\u00f3","year":"2006","unstructured":"Ali\u00f3 JL, Shabayek MH. Corneal higher order aberrations: a method to grade keratoconus. J Refract Surg. 2006;22(6):539\u201345.","journal-title":"J Refract Surg"},{"key":"717_CR5","unstructured":"Szczotka, L.B., Y.S. Rabinowitz, and H. Yang, Influence of contact lens wear on the corneal topography of keratoconus. The CLAO journal: official publication of the Contact Lens Association of Ophthalmologists, Inc, 1996. 22(4): p. 270\u2013273."},{"issue":"5","key":"717_CR6","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","volume":"135","author":"G Wollensak","year":"2003","unstructured":"Wollensak G, Spoerl E, Seiler T. Riboflavin\/ultraviolet-A\u2013induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135(5):620\u20137.","journal-title":"Am J Ophthalmol"},{"issue":"11","key":"717_CR7","doi-asserted-by":"publisher","first-page":"746","DOI":"10.3928\/1081597X-20141021-06","volume":"30","author":"P Vinciguerra","year":"2014","unstructured":"Vinciguerra P, et\u00a0al. Transepithelial iontophoresis corneal collagen cross-linking for progressive keratoconus: initial clinical outcomes. J Refract Surg. 2014;30(11):746\u201353.","journal-title":"J Refract Surg"},{"issue":"4","key":"717_CR8","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1016\/j.jcrs.2003.12.005","volume":"30","author":"S Kwitko","year":"2004","unstructured":"Kwitko S, Severo NS. Ferrara intracorneal ring segments for keratoconus. J Cataract Refract Surg. 2004;30(4):812\u201320.","journal-title":"J Cataract Refract Surg"},{"issue":"10","key":"717_CR9","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1016\/j.jcrs.2014.01.047","volume":"40","author":"P Pe\u00f1a-Garc\u00eda","year":"2014","unstructured":"Pe\u00f1a-Garc\u00eda P, et\u00a0al. Internal, corneal, and refractive astigmatism as prognostic factors for intrastromal corneal ring segment implantation in mild to moderate keratoconus. J Cataract Refract Surg. 2014;40(10):1633\u201344.","journal-title":"J Cataract Refract Surg"},{"issue":"4","key":"717_CR10","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.1097\/ICO.0b013e31825ca70b","volume":"32","author":"AF Amayem","year":"2013","unstructured":"Amayem AF, Hamdi IM, Hamdi MM. Refractive and visual outcomes of penetrating keratoplasty versus deep anterior lamellar keratoplasty with hydrodissection for treatment of keratoconus. Cornea. 2013;32(4):e2\u20135.","journal-title":"Cornea"},{"issue":"7","key":"717_CR11","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1097\/ICO.0b013e31819839c6","volume":"28","author":"D Kook","year":"2009","unstructured":"Kook D, et\u00a0al. Top-hat shaped corneal trephination for penetrating keratoplasty using the femtosecond laser: a histomorphological study. Cornea. 2009;28(7):795\u2013800.","journal-title":"Cornea"},{"issue":"2","key":"717_CR12","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1111\/cxo.12237","volume":"98","author":"Y Wu","year":"2015","unstructured":"Wu Y, et\u00a0al. Rigid gas-permeable contact lens related life quality in keratoconic patients with different grades of severity. Clin Exp Optom. 2015;98(2):150\u20134.","journal-title":"Clin Exp Optom"},{"key":"717_CR13","doi-asserted-by":"crossref","unstructured":"Aydin Kurna, S., et\u00a0al., Vision related quality of life in patients with keratoconus. Journal of ophthalmology, 2014. 2014.","DOI":"10.1155\/2014\/694542"},{"issue":"6","key":"717_CR14","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1097\/ICL.0000000000000129","volume":"41","author":"AK Cingu","year":"2015","unstructured":"Cingu AK, et\u00a0al. Impact of collagen cross-linking on psychological distress and vision and health-related quality of life in patients with keratoconus. Eye Contact Lens. 2015;41(6):349\u201353.","journal-title":"Eye Contact Lens"},{"issue":"4","key":"717_CR15","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.ajo.2004.04.031","volume":"138","author":"SM Kymes","year":"2004","unstructured":"Kymes SM, et\u00a0al. Quality of life in keratoconus. Am J Ophthalmol. 2004;138(4):527\u201335.","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"717_CR16","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1097\/OPX.0000000000001035","volume":"94","author":"J Khadka","year":"2017","unstructured":"Khadka J, Schoneveld PG, Pesudovs K. Development of a keratoconus-specific questionnaire using Rasch analysis. Optom Vis Sci. 2017;94(3):395\u2013403.","journal-title":"Optom Vis Sci"},{"key":"717_CR17","unstructured":"US Department of Health Human Services, et\u00a0al., Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance. Health and Quality of Life Outcomes, 2009. 4: p. 1\u201320."},{"issue":"1","key":"717_CR18","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1477-7525-12-15","volume":"12","author":"A Br\u00e9dart","year":"2014","unstructured":"Br\u00e9dart A, et\u00a0al. Interviewing to develop Patient-Reported Outcome (PRO) measures for clinical research: eliciting patients\u2019 experience. Health Qual Life Outcomes. 2014;12(1):15.","journal-title":"Health Qual Life Outcomes"},{"issue":"8","key":"717_CR19","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1007\/s11136-010-9677-6","volume":"19","author":"KE Lasch","year":"2010","unstructured":"Lasch KE, et\u00a0al. PRO development: rigorous qualitative research as the crucial foundation. Qual Life Res. 2010;19(8):1087\u201396.","journal-title":"Qual Life Res"},{"key":"717_CR20","unstructured":"Boyatzis, R.E., Transforming qualitative information: Thematic analysis and code development. 1998: sage."},{"key":"717_CR21","unstructured":"Friese, S., ATLAS. ti 7 user guide and reference. Berlin: ATLAS. ti Scientific Software Development GmbH, 2013."},{"issue":"1","key":"717_CR22","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1177\/1525822X05279903","volume":"18","author":"G Guest","year":"2006","unstructured":"Guest G, Bunce A, Johnson L. How many interviews are enough? An experiment with data saturation and variability. Field Methods. 2006;18(1):59\u201382.","journal-title":"Field Methods"},{"key":"717_CR23","volume-title":"Basics of qualitative research techniques","author":"A Strauss","year":"1998","unstructured":"Strauss A, Corbin J. Basics of qualitative research techniques. CA: Sage publications Thousand Oaks; 1998."},{"issue":"3","key":"717_CR24","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1023\/A:1023254226592","volume":"12","author":"D Collins","year":"2003","unstructured":"Collins D. Pretesting survey instruments: An overview of cognitive methods. Qual Life Res. 2003;12(3):229\u201338.","journal-title":"Qual Life Res"},{"issue":"3","key":"717_CR25","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1023\/A:1023233432721","volume":"12","author":"E McColl","year":"2003","unstructured":"McColl E, Meadows K, Barofsky I. Cognitive aspects of survey methodology and quality of life assessment. Qual Life Res. 2003;12(3):217\u20138.","journal-title":"Qual Life Res"},{"issue":"6","key":"717_CR26","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1111\/j.1444-0938.2003.tb03082.x","volume":"86","author":"CW McMonnies","year":"2003","unstructured":"McMonnies CW, Boneham GC. Keratoconus, allergy, itch, eye-rubbing and hand-dominance. Clin Exp Optom. 2003;86(6):376\u201384.","journal-title":"Clin Exp Optom"},{"issue":"1","key":"717_CR27","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1001\/jama.1995.03520250075037","volume":"273","author":"IB Wilson","year":"1995","unstructured":"Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life: a conceptual model of patient outcomes. JAMA. 1995;273(1):59\u201365.","journal-title":"JAMA"},{"issue":"11","key":"717_CR28","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.1001\/archopht.116.11.1496","volume":"116","author":"CM Mangione","year":"1998","unstructured":"Mangione CM, et\u00a0al. Psychometric properties of the National Eye Institute visual function questionnaire (NEI-VFQ). Arch Ophthalmol. 1998;116(11):1496\u2013504.","journal-title":"Arch Ophthalmol"},{"issue":"7","key":"717_CR29","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1001\/archopht.119.7.1050","volume":"119","author":"CM Mangione","year":"2001","unstructured":"Mangione CM, et\u00a0al. Development of the 25-list-item national eye institute visual function questionnaire. Arch Ophthalmol. 2001;119(7):1050\u20138.","journal-title":"Arch Ophthalmol"},{"issue":"1","key":"717_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13023-018-0810-x","volume":"13","author":"A Slade","year":"2018","unstructured":"Slade A, et\u00a0al. Patient reported outcome measures in rare diseases: a narrative review. Orphanet J Rare Dis. 2018;13(1):1\u20139.","journal-title":"Orphanet J Rare Dis"},{"issue":"9","key":"717_CR31","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1007\/s11136-009-9540-9","volume":"18","author":"M Brod","year":"2009","unstructured":"Brod M, Tesler LE, Christensen TL. Qualitative research and content validity: developing best practices based on science and experience. Qual Life Res. 2009;18(9):1263.","journal-title":"Qual Life Res"}],"container-title":["Ophthalmology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-023-00717-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40123-023-00717-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-023-00717-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T02:47:33Z","timestamp":1687488453000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40123-023-00717-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,8]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["717"],"URL":"https:\/\/doi.org\/10.1007\/s40123-023-00717-w","relation":{},"ISSN":["2193-8245","2193-6528"],"issn-type":[{"value":"2193-8245","type":"print"},{"value":"2193-6528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,8]]},"assertion":[{"value":"17 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}