{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T22:25:15Z","timestamp":1768256715944,"version":"3.49.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T00:00:00Z","timestamp":1729814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T00:00:00Z","timestamp":1729814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100013968","name":"Johnson and Johnson Vision Care","doi-asserted-by":"publisher","award":["DHC-1258"],"award-info":[{"award-number":["DHC-1258"]}],"id":[{"id":"10.13039\/100013968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmol Ther"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>This study is a prospective, randomized, subject\/evaluator-masked clinical trial in a single-center clinical setting. The purpose of the study is to compare the clinical performance of Tecnis Symfony Optiblue IOL (models ZXR00V and ZXW150) with violet light filter (VLF) and manufacturing improvements versus Tecnis Symfony IOL (models ZXR00 and ZXT150) with ultraviolet light filter (UVF) in patients undergoing cataract surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Patients with cataracts aged\u2009\u2265\u200922\u00a0years were randomly assigned 1:1 to bilateral implantation with ZXR00V\/ZXW150 (VLF group) or ZXR00\/ZXT150 (UVF group). Key endpoints at 6\u00a0months postoperative included patient reported nighttime dysphotopsia symptoms, 25% low contrast visual acuity with glare, and patient satisfaction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sixty patients were implanted with ZXR00V\/ZXW150 (30) or ZXR00\/ZXT150 (30). At 6\u00a0months, the VLF group did not show a statistically significant differences in mean monocular photopic uncorrected distance visual acuity (UCDVA), best-corrected distance visual acuity (BCDVA), uncorrected near visual acuity (UCNVA) (40\u00a0cm), or distance-corrected near visual acuity (DCNVA) (40\u00a0cm) compared to the UVF group. At 1\u00a0month, patients in the VLF group reported significantly less difficulty due to halo (<jats:italic>p<\/jats:italic>\u2009=\u20090.016) and starburst (<jats:italic>p<\/jats:italic>\u2009=\u20090.028) symptoms. By the 6\u00a0months, dysphotopsia complaints were no longer significantly different between the groups. Although the VLF group trended toward better low contrast visual acuity and patient satisfaction, statistical significance was not reached.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Managing the patients\u2019 expectations is key to achieving success. At the 1-month visit the patients who reported dysphotopsia complaints in the VLF group had significantly less difficulty with starbursts and halos as compared to the UVF group. By the 6-month visit, there was no significant difference between the two groups in the difficulty with starbursts and halos.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Trial Registration<\/jats:title>\n                <jats:p>ClinicalTrials.gov identifier, NCT06567834.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40123-024-01056-0","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T21:01:33Z","timestamp":1729890093000},"page":"3135-3147","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Evaluation of Violet Light Filtration and High-Resolution Lathing on a Diffractive Extended Depth of Focus IOL"],"prefix":"10.1007","volume":"13","clinical-trial-number":[{"clinical-trial-number":"nct06567834","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6307-6342","authenticated-orcid":false,"given":"Daniel H.","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew A.","family":"Kao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura K.","family":"Huggins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline N.","family":"Albert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline N.","family":"Whinery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany M.","family":"Camirand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,25]]},"reference":[{"issue":"3","key":"1056_CR1","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1097\/j.jcrs.0000000000000747","volume":"48","author":"DH Chang","year":"2022","unstructured":"Chang DH, Janakiraman DP, Smith PJ, et al. Visual outcomes and safety of an extended depth-of-focus intraocular lens: results of a pivotal clinical trial. J Catar Refract Surg. 2022;48(3):288\u201397. https:\/\/doi.org\/10.1097\/j.jcrs.0000000000000747.","journal-title":"J Catar Refract Surg"},{"key":"1056_CR2","unstructured":"US Food and Drug Administration. TECNIS symfony extended range of vision intraocular lens (IOL) (Model ZXR00), TECNIS Symfony Toric IOL (Models ZXT150, ZXT225, ZXT300, ZXT375): P980040\/S065. Silver Spring, MD: US Food and Drug Administration; 2016."},{"key":"1056_CR3","unstructured":"US Food and Drug Administration. TECNIS symfony optiblue extended range of vision intraocular lens (IOLs, model ZXR00V and the TECNIS symfony toric II OptiBlue extended range of vision intraocular lens IOLs, model ZXW150, ZXW225, ZXW300, and ZXW375). 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Chang, MD is an investigator and consultant for Johnson & Johnson Vision and an investigator for Beaver-Visitec International and Ocuphire. Andrew A. Kao, MD is an investigator for Glaukos Corp, Johnson & Johnson Vision and Beaver-Visitec International. Laura K. Huggins, OD in an investigator for Glaukos Corp, Johnson & Johnson Vision, Ocuphire and Beaver-Visitec International. Jacqueline N. Albert, OD in an investigator for Glaukos Corp, Johnson & Johnson Vision, Ocuphire and Beaver-Visitec International. Jacqueline N. Whinery, CCRC, COA and Brittany M. Camirand, COT have no competing interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This study was approved by the regulatory and institutional review board, Salus IRB, and was conducted in accordance with the US Code of Federal Regulations, the Declaration of Helsinki, ISO 14155:2011, and all other applicable laws and regulations. All patients provided written informed consent and gave health information access authorization in accordance with HIPAA guidelines prior to participating in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}