{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:05:28Z","timestamp":1786982728028,"version":"build-2736575974"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmol Ther"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1007\/s40123-025-01205-z","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T17:45:58Z","timestamp":1752774358000},"page":"2165-2178","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Immediate Impact of Artificial Tear Composition on Optical Aberrations: A Comparative Study of Lipid and Non-Lipid Hydroxypropyl Guar Formulations"],"prefix":"10.1007","volume":"14","clinical-trial-number":[{"clinical-trial-number":"nct06784661","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0450-7717","authenticated-orcid":false,"given":"Jos\u00e9-Mar\u00eda","family":"S\u00e1nchez-Gonz\u00e1lez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Carmen","family":"S\u00e1nchez-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concepci\u00f3n","family":"De-Hita-Cantalejo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique","family":"Nascimento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Martinez-Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"1205_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/jcm10061289","volume":"10","author":"A Kathuria","year":"2021","unstructured":"Kathuria A, Shamloo K, Jhanji V, Sharma A. Categorization of marketed artificial tear formulations based on their ingredients: a rational approach for their use. J Clin Med. 2021;10:1\u201311.","journal-title":"J Clin Med"},{"key":"1205_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms22052747","volume":"22","author":"P Eftimov","year":"2021","unstructured":"Eftimov P, Yokoi N, Melo AM, Daull P, Georgiev GA. Interactions of meibum and tears with mucomimetic polymers: a hint towards the interplay between the layers of the tear film. Int J Mol Sci. 2021;22:1\u201315.","journal-title":"Int J Mol Sci"},{"key":"1205_CR3","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.3390\/foods11162508","volume":"11","author":"X Xu","year":"2022","unstructured":"Xu X, Ye S, Zuo X, Fang S. Impact of guar gum and locust bean gum addition on the pasting, rheological properties, and freeze\u2013thaw stability of rice starch gel. Foods. 2022;11:2508.","journal-title":"Foods"},{"key":"1205_CR4","doi-asserted-by":"publisher","first-page":"3311","DOI":"10.2147\/OPTH.S377960","volume":"16","author":"S Srinivasan","year":"2022","unstructured":"Srinivasan S, Williams R. Propylene glycol and hydroxypropyl guar nanoemulsion-safe and effective lubricant eye drops in the management of dry eye disease. Clin Ophthalmol. 2022;16:3311\u201326.","journal-title":"Clin Ophthalmol"},{"key":"1205_CR5","doi-asserted-by":"publisher","first-page":"3883","DOI":"10.2147\/OPTH.S428725","volume":"17","author":"S Srinivasan","year":"2023","unstructured":"Srinivasan S, Garofalo R, Williams R. Safe and effective management of dry eye symptoms with hydroxypropyl guar and hyaluronic acid dual-polymer lubricating eye drops: a review of preclinical and clinical studies. Clin Ophthalmol. 2023;17:3883\u201398.","journal-title":"Clin Ophthalmol"},{"key":"1205_CR6","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1111\/aos.15159","volume":"100","author":"L Hynnekleiv","year":"2022","unstructured":"Hynnekleiv L, Magno M, Vernhardsdottir RR, Moschowits E, T\u00f8nseth KA, Dartt DA, et\u00a0al. Hyaluronic acid in the treatment of dry eye disease. Acta Ophthalmol. 2022;100:844\u201360.","journal-title":"Acta Ophthalmol"},{"key":"1205_CR7","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1080\/02713683.2022.2039205","volume":"47","author":"M Rolando","year":"2022","unstructured":"Rolando M, Merayo-Lloves J. Management strategies for evaporative dry eye disease and future perspective. Curr Eye Res. 2022;47:813\u201323.","journal-title":"Curr Eye Res"},{"key":"1205_CR8","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.18240\/ijo.2020.09.05","volume":"13","author":"JM S\u00e1nchez-Gonz\u00e1lez","year":"2020","unstructured":"S\u00e1nchez-Gonz\u00e1lez JM, De-Hita-Cantalejo C, S\u00e1nchezGonz\u00e1lez MC. Crosslinked hyaluronic acid with liposomes and crocin for management symptoms of dry eye disease caused by moderate meibomian gland dysfunction. Int J Ophthalmol. 2020;13:1368\u201373.","journal-title":"Int J Ophthalmol"},{"key":"1205_CR9","doi-asserted-by":"publisher","first-page":"S83","DOI":"10.1097\/ICO.0000000000000998","volume":"35","author":"S Koh","year":"2016","unstructured":"Koh S. Mechanisms of visual disturbance in dry eye. Cornea. 2016;35:S83\u20138.","journal-title":"Cornea"},{"key":"1205_CR10","doi-asserted-by":"publisher","first-page":"597","DOI":"10.3390\/bioengineering11060597","volume":"11","author":"A Kawahara","year":"2024","unstructured":"Kawahara A. Management of dry eye disease for intraocular lens power calculation in cataract surgery: a systematic review. Bioengineering. 2024;11:597.","journal-title":"Bioengineering"},{"key":"1205_CR11","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s40123-021-00419-1","volume":"11","author":"J Rhee","year":"2022","unstructured":"Rhee J, Chan TCY, Chow SSW, Di Zazzo A, Inomata T, Shih KC, et\u00a0al. A systematic review on the association between tear film metrics and higher order aberrations in dry eye disease and treatment. Ophthalmol Ther. 2022;11:35\u201367.","journal-title":"Ophthalmol Ther"},{"key":"1205_CR12","doi-asserted-by":"publisher","first-page":"407","DOI":"10.18240\/ijo.2022.03.06","volume":"15","author":"RJ Liu","year":"2022","unstructured":"Liu RJ, Ma BK, Gao YF, Liu YY, Qi H. Evaluations of wavefront aberrations and corneal surface regularity in dry eye patients measured with OPD Scan III. Int J Ophthalmol. 2022;15:407\u201312.","journal-title":"Int J Ophthalmol"},{"key":"1205_CR13","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1007\/s40123-023-00693-1","volume":"12","author":"R Ning","year":"2023","unstructured":"Ning R, Huang X, Jin Y, Lei CS, Ma X, Xu S, et\u00a0al. Corneal higher-order aberrations measurements: precision of SD-OCT\/Placido topography and comparison with a Scheimpflug\/Placido topography in eyes after small-incision lenticule extraction. Ophthalmol Ther. 2023;12:1595\u2013610.","journal-title":"Ophthalmol Ther"},{"key":"1205_CR14","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1007\/s40123-021-00392-9","volume":"10","author":"A Russo","year":"2021","unstructured":"Russo A, Filini O, Salvalai C, Boldini A, Festa G, Delcassi L, et\u00a0al. Two-year changes in corneal spherical aberration after laser-assisted in situ keratomileusis and photorefractive keratectomy in regular and wavefront-guided ablations. Ophthalmol Ther. 2021;10:1003\u201314.","journal-title":"Ophthalmol Ther"},{"key":"1205_CR15","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1007\/s40123-023-00684-2","volume":"12","author":"G Velarde-Rodriguez","year":"2023","unstructured":"Velarde-Rodriguez G, Belda-Para C, Velasco-Oca\u00f1a M, Trujillo-Sevilla JM, Rodr\u00edguez-Martin J, Jim\u00e9nez-Alfaro I, et\u00a0al. Ultra-high resolution optical aberrometry in patients with keratoconus: a cross-sectional study. Ophthalmol Ther. 2023;12:1569\u201382.","journal-title":"Ophthalmol Ther"},{"key":"1205_CR16","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s40123-022-00608-6","volume":"12","author":"F Yang","year":"2023","unstructured":"Yang F, Bao Y. Correlations of corneal curvature with corneal spherical aberration and anterior chamber parameters in eyes with shallow anterior chambers. Ophthalmol Ther. 2023;12:239\u201349.","journal-title":"Ophthalmol Ther"},{"key":"1205_CR17","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/j.jcrs.2009.12.044","volume":"36","author":"R Mont\u00e9s-Mic\u00f3","year":"2010","unstructured":"Mont\u00e9s-Mic\u00f3 R, Cervi\u00f1o A, Ferrer-Blasco T, Garc\u00eda-L\u00e1zaro S, Ort\u00ed-Navarro S. Optical quality after instillation of eyedrops in dry-eye syndrome. J Cataract Refract Surg. 2010;36:935\u201340.","journal-title":"J Cataract Refract Surg"},{"key":"1205_CR18","doi-asserted-by":"publisher","first-page":"2080","DOI":"10.1016\/j.ophtha.2010.03.028","volume":"117","author":"T Hiraoka","year":"2010","unstructured":"Hiraoka T, Daito M, Okamoto F, Kiuchi T, Oshika T. Contrast sensitivity and optical quality of the eye after instillation of timolol maleate gel-forming solution and brinzolamide ophthalmic suspension. Ophthalmology. 2010;117:2080\u20137.","journal-title":"Ophthalmology"},{"key":"1205_CR19","doi-asserted-by":"publisher","first-page":"4927","DOI":"10.1167\/iovs.13-12409","volume":"54","author":"S Koh","year":"2013","unstructured":"Koh S, Maeda N, Ikeda C, Takai Y, Fujimoto H, Oie Y, et\u00a0al. Effect of instillation of eyedrops for dry eye on optical quality. Investig Ophthalmol Vis Sci. 2013;54:4927\u201333.","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"1205_CR20","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1097\/ICO.0000000000001523","volume":"37","author":"K Mih\u00e1ltz","year":"2018","unstructured":"Mih\u00e1ltz K, Maria Faschinger E, V\u00e9csei-Marlovits PV. Effects of lipid- Versus sodium hyaluronate-containing eye drops on optical quality and ocular surface parameters as a function of the meibomian gland dropout rate. Cornea. 2018;37:886\u201392.","journal-title":"Cornea"},{"key":"1205_CR21","first-page":"232","volume":"18","author":"LN Thibos","year":"2000","unstructured":"Thibos LN, Applegate RA, Schwiegerling JT, Webb R. Standards for reporting the optical aberrations of eyes. Opt InfoBase Conf Pap. 2000;18:232\u201344.","journal-title":"Opt InfoBase Conf Pap."},{"key":"1205_CR22","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/S0886-3350(00)00797-5","volume":"27","author":"LN Thibos","year":"2001","unstructured":"Thibos LN, Horner D. Power vector analysis of the optical outcome of refractive surgery. J Cataract Refract Surg. 2001;27:80\u20135.","journal-title":"J Cataract Refract Surg"},{"key":"1205_CR23","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.jconrel.2017.03.008","volume":"252","author":"Y Singh","year":"2017","unstructured":"Singh Y, Meher JG, Raval K, Khan FA, Chaurasia M, Jain NK, et\u00a0al. Nanoemulsion: concepts, development and applications in drug delivery. J Control Release. 2017;252:28\u201349.","journal-title":"J Control Release"},{"key":"1205_CR24","doi-asserted-by":"publisher","first-page":"2649","DOI":"10.3390\/molecules25112649","volume":"25","author":"IS Bayer","year":"2020","unstructured":"Bayer IS. Hyaluronic acid and controlled release: a review. Molecules. 2020;25:2649.","journal-title":"Molecules"},{"key":"1205_CR25","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1097\/OPX.0000000000000101","volume":"91","author":"K Lekhanont","year":"2014","unstructured":"Lekhanont K, Chuckpaiwong V, Vongthongsri A, Sangiampornpanit T. Effects of sodium hyaluronate on wavefront aberrations in dry eye patients. Optom Vis Sci. 2014;91:39\u201346.","journal-title":"Optom Vis Sci"},{"key":"1205_CR26","doi-asserted-by":"publisher","first-page":"e0279977","DOI":"10.1371\/journal.pone.0279977","volume":"18","author":"KJ Habbe","year":"2023","unstructured":"Habbe KJ, Frings A, Saad A, Geerling G. The influence of a mineral oil cationic nanoemulsion or perfluorohexyloctane on the tear film lipid layer and higher order aberrations. PLoS ONE. 2023;18:e0279977. https:\/\/doi.org\/10.1371\/journal.pone.0279977.","journal-title":"PLoS ONE"},{"key":"1205_CR27","doi-asserted-by":"publisher","first-page":"5025","DOI":"10.1007\/s10792-023-02905-w","volume":"43","author":"A Saad","year":"2023","unstructured":"Saad A, Frings A. Influence of perfluorohexyloctane (Evotears\u00ae) on higher order aberrations. Int Ophthalmol. 2023;43:5025\u201330. https:\/\/doi.org\/10.1007\/s10792-023-02905-w.","journal-title":"Int Ophthalmol"},{"key":"1205_CR28","doi-asserted-by":"publisher","first-page":"101471","DOI":"10.1016\/j.clae.2021.101471","volume":"44","author":"C Carpena-Torres","year":"2021","unstructured":"Carpena-Torres C, Pastrana C, Rodr\u00edguez-Pomar C, Serramito M, Batres L, Carracedo G. Changes in visual quality with soft contact lenses after the instillation of hyaluronic acid eye drops. Contact Lens Anterior Eye. 2021;44:101471. https:\/\/doi.org\/10.1016\/j.clae.2021.101471.","journal-title":"Contact Lens Anterior Eye."}],"container-title":["Ophthalmology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-025-01205-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40123-025-01205-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-025-01205-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T13:10:19Z","timestamp":1757250619000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40123-025-01205-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,17]]},"references-count":28,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["1205"],"URL":"https:\/\/doi.org\/10.1007\/s40123-025-01205-z","relation":{},"ISSN":["2193-8245","2193-6528"],"issn-type":[{"value":"2193-8245","type":"print"},{"value":"2193-6528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,17]]},"assertion":[{"value":"3 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Jos\u00e9-Mar\u00eda S\u00e1nchez-Gonz\u00e1lez is an Advisory Board Member of\n                      Ophthalmology and Therapy\n                      . Jos\u00e9-Mar\u00eda S\u00e1nchez-Gonz\u00e1lez was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. Mar\u00eda Carmen S\u00e1nchez-Gonz\u00e1lez, Concepci\u00f3n De-Hita-Cantalejo, Henrique Nascimento, and Clara Martinez-Perez have nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}},{"value":"The study was approved by the Ethics Committee of the University of ISEC Lisboa (Instituto Superior de Educa\u00e7\u00e3o e Ci\u00eancias). All procedures adhered to the ethical standards outlined by the Declaration of Helsinki and local regulatory requirements.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}