{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T23:18:57Z","timestamp":1793488737122,"version":"4.5.0"},"reference-count":190,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmol Ther"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s40123-025-01286-w","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T05:39:31Z","timestamp":1764826771000},"page":"85-128","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Current Landscape and Future Prospects of Corneal Regenerative Medicine"],"prefix":"10.1007","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2617-0289","authenticated-orcid":false,"given":"Giuseppe","family":"Giannaccare","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Lixi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Slidsborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamze","family":"Ozkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina Gabriela","family":"Gheorghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana-Maria","family":"Arghirescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assem","family":"Namazbayeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mana","family":"Monfared","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan Bir","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Jhanji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Nucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Coco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,4]]},"reference":[{"issue":"2","key":"1286_CR1","doi-asserted-by":"publisher","first-page":"190","DOI":"10.4103\/ijo.IJO_646_17","volume":"66","author":"MS Sridhar","year":"2018","unstructured":"Sridhar MS. Anatomy of cornea and ocular surface. Indian J Ophthalmol. 2018;66(2):190\u20134. https:\/\/doi.org\/10.4103\/ijo.IJO_646_17.","journal-title":"Indian J Ophthalmol"},{"issue":"3","key":"1286_CR2","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/j.jcrs.2010.12.037","volume":"37","author":"DW DelMonte","year":"2011","unstructured":"DelMonte DW, Kim T. Anatomy and physiology of the cornea. J Cataract Refract Surg. 2011;37(3):588\u201398. https:\/\/doi.org\/10.1016\/j.jcrs.2010.12.037.","journal-title":"J Cataract Refract Surg"},{"issue":"9","key":"1286_CR3","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.1016\/j.ophtha.2013.01.018","volume":"120","author":"HS Dua","year":"2013","unstructured":"Dua HS, Faraj LA, Said DG, Gray T, Lowe J. Human corneal anatomy redefined: a novel pre-Descemet\u2019s layer (Dua\u2019s layer). Ophthalmology. 2013;120(9):1778\u201385. https:\/\/doi.org\/10.1016\/j.ophtha.2013.01.018.","journal-title":"Ophthalmology"},{"key":"1286_CR4","unstructured":"World report on vision. Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO."},{"issue":"2","key":"1286_CR5","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1001\/jamaophthalmol.2015.4776","volume":"134","author":"P Gain","year":"2016","unstructured":"Gain P, Jullienne R, He Z, et al. Global survey of corneal transplantation and eye banking. JAMA Ophthalmol. 2016;134(2):167\u201373. https:\/\/doi.org\/10.1001\/jamaophthalmol.2015.4776.","journal-title":"JAMA Ophthalmol"},{"issue":"4","key":"1286_CR6","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1097\/icu.0000000000000964","volume":"34","author":"R Kaufman","year":"2023","unstructured":"Kaufman R, Jun AS. Recent advances in cell-based regenerative therapies for corneal disease. Curr Opin Ophthalmol. 2023;34(4):303\u201310. https:\/\/doi.org\/10.1097\/icu.0000000000000964.","journal-title":"Curr Opin Ophthalmol"},{"key":"1286_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering10111284","author":"M Chi","year":"2023","unstructured":"Chi M, Yuan B, Xie Z, Hong J. The innovative biomaterials and technologies for developing corneal endothelium tissue engineering scaffolds: a review and prospect. Bioengineering. 2023. https:\/\/doi.org\/10.3390\/bioengineering10111284.","journal-title":"Bioengineering"},{"issue":"10","key":"1286_CR8","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1039\/d1bm02023d","volume":"10","author":"J Delaey","year":"2022","unstructured":"Delaey J, De Vos L, Koppen C, Dubruel P, Van Vlierberghe S, Van den Bogerd B. Tissue engineered scaffolds for corneal endothelial regeneration: a material\u2019s perspective. Biomater Sci. 2022;10(10):2440\u201361. https:\/\/doi.org\/10.1039\/d1bm02023d.","journal-title":"Biomater Sci"},{"issue":"1","key":"1286_CR9","volume":"7","author":"EOE Eghosasere","year":"2025","unstructured":"Eghosasere EOE, Emmanuella O. 3D bioprinting in tissue engineering: advancements, challenges, and pathways to clinical translation. JSM Regen Med Bio Eng. 2025;7(1):1023.","journal-title":"JSM Regen Med Bio Eng"},{"issue":"1","key":"1286_CR10","doi-asserted-by":"publisher","first-page":"25755","DOI":"10.1038\/s41598-025-10434-y","volume":"15","author":"L Meneux","year":"2025","unstructured":"Meneux L, Pernot S, Feret N, et al. Injury-specific pathways shape corneal nerve regeneration dynamics. Sci Rep. 2025;15(1):25755. https:\/\/doi.org\/10.1038\/s41598-025-10434-y.","journal-title":"Sci Rep"},{"issue":"9","key":"1286_CR11","doi-asserted-by":"publisher","first-page":"6390","DOI":"10.1167\/iovs.13-12547","volume":"54","author":"AA Torricelli","year":"2013","unstructured":"Torricelli AA, Singh V, Santhiago MR, Wilson SE. The corneal epithelial basement membrane: structure, function, and disease. Invest Ophthalmol Vis Sci. 2013;54(9):6390\u2013400. https:\/\/doi.org\/10.1167\/iovs.13-12547.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"1286_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.exer.2012.03.006","volume":"98","author":"V Singh","year":"2012","unstructured":"Singh V, Agrawal V, Santhiago MR, Wilson SE. Stromal fibroblast-bone marrow-derived cell interactions: implications for myofibroblast development in the cornea. Exp Eye Res. 2012;98(1):1\u20138. https:\/\/doi.org\/10.1016\/j.exer.2012.03.006.","journal-title":"Exp Eye Res"},{"issue":"2","key":"1286_CR13","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/0092-8674(89)90958-6","volume":"57","author":"G Cotsarelis","year":"1989","unstructured":"Cotsarelis G, Cheng SZ, Dong G, Sun TT, Lavker RM. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell. 1989;57(2):201\u20139. https:\/\/doi.org\/10.1016\/0092-8674(89)90958-6.","journal-title":"Cell"},{"issue":"5","key":"1286_CR14","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1136\/bjo.2004.049742","volume":"89","author":"HS Dua","year":"2005","unstructured":"Dua HS, Shanmuganathan VA, Powell-Richards AO, Tighe PJ, Joseph A. Limbal epithelial crypts: a novel anatomical structure and a putative limbal stem cell niche. Br J Ophthalmol. 2005;89(5):529\u201332. https:\/\/doi.org\/10.1136\/bjo.2004.049742.","journal-title":"Br J Ophthalmol"},{"key":"1286_CR15","first-page":"155","volume":"80","author":"MF Goldberg","year":"1982","unstructured":"Goldberg MF, Bron AJ. Limbal palisades of Vogt. Trans Am Ophthalmol Soc. 1982;80:155\u201371.","journal-title":"Trans Am Ophthalmol Soc"},{"issue":"5","key":"1286_CR16","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1001\/archopht.1961.01840020697016","volume":"65","author":"C Hanna","year":"1961","unstructured":"Hanna C, Bicknell DS, O\u2019Brien JE. Cell turnover in the adult human eye. Arch Ophthalmol. 1961;65(5):695\u20138. https:\/\/doi.org\/10.1001\/archopht.1961.01840020697016.","journal-title":"Arch Ophthalmol"},{"issue":"1","key":"1286_CR17","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jtos.2017.11.002","volume":"16","author":"Q Le","year":"2018","unstructured":"Le Q, Xu J, Deng SX. The diagnosis of limbal stem cell deficiency. Ocul Surf. 2018;16(1):58\u201369. https:\/\/doi.org\/10.1016\/j.jtos.2017.11.002.","journal-title":"Ocul Surf"},{"key":"1286_CR18","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.ajo.2018.01.020","volume":"188","author":"J Vazirani","year":"2018","unstructured":"Vazirani J, Nair D, Shanbhag S, Wurity S, Ranjan A, Sangwan V. Limbal Stem Cell Deficiency-Demography and Underlying Causes. Am J Ophthalmol. 2018;188:99\u2013103. https:\/\/doi.org\/10.1016\/j.ajo.2018.01.020.","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"1286_CR19","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.jtos.2016.06.003","volume":"14","author":"J Rossen","year":"2016","unstructured":"Rossen J, Amram A, Milani B, Park D, Harthan J, Joslin C, et al. Contact lens-induced limbal stem cell deficiency. Ocul Surf. 2016;14(4):419\u201334. https:\/\/doi.org\/10.1016\/j.jtos.2016.06.003.","journal-title":"Ocul Surf"},{"key":"1286_CR20","doi-asserted-by":"publisher","DOI":"10.3389\/fopht.2024.1392106","volume":"4","author":"JS Goldberg","year":"2024","unstructured":"Goldberg JS, Fraser DJ, Hou JH. Prevalence of limbal stem cell deficiency at an academic referral center over a two-year period. Front Ophthalmol. 2024;4:1392106. https:\/\/doi.org\/10.3389\/fopht.2024.1392106.","journal-title":"Front Ophthalmol"},{"issue":"3","key":"1286_CR21","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1097\/ico.0000000000001820","volume":"38","author":"SX Deng","year":"2019","unstructured":"Deng SX, Borderie V, Chan CC, et al. Global consensus on definition, classification, diagnosis, and staging of limbal stem cell deficiency. Cornea. 2019;38(3):364\u201375. https:\/\/doi.org\/10.1097\/ico.0000000000001820.","journal-title":"Cornea"},{"issue":"3","key":"1286_CR22","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1097\/icl.0000000000000104","volume":"41","author":"AA Azari","year":"2015","unstructured":"Azari AA, Rapuano CJ. Autologous serum eye drops for the treatment of ocular surface disease. Eye Contact Lens Sci Clin Pract. 2015;41(3):133\u201340. https:\/\/doi.org\/10.1097\/icl.0000000000000104.","journal-title":"Eye Contact Lens Sci Clin Pract"},{"issue":"6","key":"1286_CR23","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1097\/apo.0000000000000331","volume":"9","author":"L Lim","year":"2020","unstructured":"Lim L, Lim EWL. Therapeutic contact lenses in the treatment of corneal and ocular surface diseases\u2014a review. Asia-Pac J Ophthalmol. 2020;9(6):524\u201332. https:\/\/doi.org\/10.1097\/apo.0000000000000331.","journal-title":"Asia-Pac J Ophthalmol"},{"issue":"2","key":"1286_CR24","doi-asserted-by":"publisher","first-page":"101","DOI":"10.3341\/kjo.2016.30.2.101","volume":"30","author":"JH Lee","year":"2016","unstructured":"Lee JH, Kim MJ, Ha SW, Kim HK. Autologous platelet-rich plasma eye drops in the treatment of recurrent corneal erosions. Korean J Ophthalmol. 2016;30(2):101\u20137. https:\/\/doi.org\/10.3341\/kjo.2016.30.2.101.","journal-title":"Korean J Ophthalmol"},{"issue":"9","key":"1286_CR25","doi-asserted-by":"publisher","first-page":"CD010051","DOI":"10.1002\/14651858.CD010051.pub2","volume":"9","author":"CS de Paiva","year":"2019","unstructured":"de Paiva CS, Pflugfelder SC, Ng SM, Akpek EK. Topical cyclosporine A therapy for dry eye syndrome. Cochrane Database Syst Rev. 2019;9(9):CD010051. https:\/\/doi.org\/10.1002\/14651858.CD010051.pub2.","journal-title":"Cochrane Database Syst Rev"},{"key":"1286_CR26","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232113114","author":"A Nuzzi","year":"2022","unstructured":"Nuzzi A, Pozzo Giuffrida F, Luccarelli S, Nucci P. Corneal epithelial regeneration: old and new perspectives. Int J Mol Sci. 2022. https:\/\/doi.org\/10.3390\/ijms232113114.","journal-title":"Int J Mol Sci"},{"issue":"5","key":"1286_CR27","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/s0161-6420(89)32833-8","volume":"96","author":"KR Kenyon","year":"1989","unstructured":"Kenyon KR, Tseng SC. Limbal autograft transplantation for ocular surface disorders. Ophthalmology. 1989;96(5):709\u201322. https:\/\/doi.org\/10.1016\/s0161-6420(89)32833-8.","journal-title":"Ophthalmology"},{"issue":"5","key":"1286_CR28","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1038\/eye.1993.145","volume":"7","author":"C Jenkins","year":"1993","unstructured":"Jenkins C, Tuft S, Liu C, Buckley R. Limbal transplantation in the management of chronic contact-lens-associated epitheliopathy. Eye. 1993;7(5):629\u201333. https:\/\/doi.org\/10.1038\/eye.1993.145.","journal-title":"Eye"},{"issue":"5","key":"1286_CR29","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1016\/s0161-6420(99)00516-3","volume":"106","author":"S Basti","year":"1999","unstructured":"Basti S, Mathur U. Unusual intermediate-term outcome in three cases of limbal autograft transplantation. Ophthalmology. 1999;106(5):958\u201363. https:\/\/doi.org\/10.1016\/s0161-6420(99)00516-3.","journal-title":"Ophthalmology"},{"issue":"7","key":"1286_CR30","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1016\/j.ophtha.2010.11.030","volume":"118","author":"A Miri","year":"2011","unstructured":"Miri A, Said DG, Dua HS. Donor site complications in autolimbal and living-related allolimbal transplantation. Ophthalmology. 2011;118(7):1265\u201371. https:\/\/doi.org\/10.1016\/j.ophtha.2010.11.030.","journal-title":"Ophthalmology"},{"issue":"1","key":"1286_CR31","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/s0161-6420(96)30737-9","volume":"103","author":"DT Tan","year":"1996","unstructured":"Tan DT, Ficker LA, Buckley RJ. Limbal transplantation. Ophthalmology. 1996;103(1):29\u201336. https:\/\/doi.org\/10.1016\/s0161-6420(96)30737-9.","journal-title":"Ophthalmology"},{"issue":"6","key":"1286_CR32","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1097\/QAI.0b013e31815cea8b","volume":"27","author":"A Kheirkhah","year":"2008","unstructured":"Kheirkhah A, Raju VK, Tseng SC. Minimal conjunctival\u2013limbal autograft for total limbal stem cell deficiency. Cornea. 2008;27(6):730\u20133. https:\/\/doi.org\/10.1097\/QAI.0b013e31815cea8b.","journal-title":"Cornea"},{"issue":"9","key":"1286_CR33","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1097\/ico.0000000000001260","volume":"36","author":"AY Cheung","year":"2017","unstructured":"Cheung AY, Sarnicola E, Holland EJ. Long-term ocular surface stability in conjunctival limbal autograft donor eyes. Cornea. 2017;36(9):1031\u20135. https:\/\/doi.org\/10.1097\/ico.0000000000001260.","journal-title":"Cornea"},{"issue":"6","key":"1286_CR34","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1016\/j.ophtha.2009.10.028","volume":"117","author":"A Miri","year":"2010","unstructured":"Miri A, Al-Deiri B, Dua HS. Long-term outcomes of autolimbal and allolimbal transplants. Ophthalmology. 2010;117(6):1207\u201313. https:\/\/doi.org\/10.1016\/j.ophtha.2009.10.028.","journal-title":"Ophthalmology"},{"issue":"8","key":"1286_CR35","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1097\/ICO.0b013e31823f095d","volume":"31","author":"A Baradaran-Rafii","year":"2012","unstructured":"Baradaran-Rafii A, Eslani M, Jamali H, Karimian F, Tailor UA, Djalilian AR. Postoperative complications of conjunctival limbal autograft surgery. Cornea. 2012;31(8):893\u20139. https:\/\/doi.org\/10.1097\/ICO.0b013e31823f095d.","journal-title":"Cornea"},{"issue":"4","key":"1286_CR36","doi-asserted-by":"publisher","first-page":"207","DOI":"10.5935\/0004-2749.20150054","volume":"78","author":"PB Moreira","year":"2015","unstructured":"Moreira PB, Magalh\u00e3es RS, Pereira NC, Oliveira LA, Sousa LB. Limbal transplantation at a tertiary hospital in Brazil: a retrospective study. Arq Bras Oftalmol. 2015;78(4):207\u201311. https:\/\/doi.org\/10.5935\/0004-2749.20150054.","journal-title":"Arq Bras Oftalmol"},{"issue":"3","key":"1286_CR37","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1136\/bjo.84.3.273","volume":"84","author":"HS Dua","year":"2000","unstructured":"Dua HS, Azuara-Blanco A. Autologous limbal transplantation in patients with unilateral corneal stem cell deficiency. Br J Ophthalmol. 2000;84(3):273\u20138. https:\/\/doi.org\/10.1136\/bjo.84.3.273.","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"1286_CR38","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1097\/00003226-199903000-00004","volume":"18","author":"SK Rao","year":"1999","unstructured":"Rao SK, Rajagopal R, Sitalakshmi G, Padmanabhan P. Limbal autografting: comparison of results in the acute and chronic phases of ocular surface burns. Cornea. 1999;18(2):164\u201371. https:\/\/doi.org\/10.1097\/00003226-199903000-00004.","journal-title":"Cornea"},{"issue":"1","key":"1286_CR39","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.ophtha.2003.02.003","volume":"111","author":"J Shimazaki","year":"2004","unstructured":"Shimazaki J, Shimmura S, Tsubota K. Donor source affects the outcome of ocular surface reconstruction in chemical or thermal burns of the cornea. Ophthalmology. 2004;111(1):38\u201344. https:\/\/doi.org\/10.1016\/j.ophtha.2003.02.003.","journal-title":"Ophthalmology"},{"issue":"3","key":"1286_CR40","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1038\/sj.eye.6700640","volume":"18","author":"O Ozdemir","year":"2004","unstructured":"Ozdemir O, Tekeli O, Ornek K, Arslanpen\u00e7e A, Yal\u00e7inda\u011f NF. Limbal autograft and allograft transplantations in patients with corneal burns. Eye (Lond). 2004;18(3):241\u20138. https:\/\/doi.org\/10.1038\/sj.eye.6700640.","journal-title":"Eye (Lond)"},{"issue":"6","key":"1286_CR41","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1177\/112067210801800605","volume":"18","author":"E Wylegala","year":"2008","unstructured":"Wylegala E, Dobrowolski D, Tarnawska D, et al. Limbal stem cells transplantation in the reconstruction of the ocular surface: 6 years experience. Eur J Ophthalmol. 2008;18(6):886\u201390. https:\/\/doi.org\/10.1177\/112067210801800605.","journal-title":"Eur J Ophthalmol"},{"key":"1286_CR42","first-page":"677","volume":"94","author":"EJ Holland","year":"1996","unstructured":"Holland EJ. Epithelial transplantation for the management of severe ocular surface disease. Trans Am Ophthalmol Soc. 1996;94:677\u2013743.","journal-title":"Trans Am Ophthalmol Soc"},{"issue":"4","key":"1286_CR43","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1097\/icu.0000000000000374","volume":"28","author":"AY Cheung","year":"2017","unstructured":"Cheung AY, Holland EJ. Keratolimbal allograft. Curr Opin Ophthalmol. 2017;28(4):377\u201381. https:\/\/doi.org\/10.1097\/icu.0000000000000374.","journal-title":"Curr Opin Ophthalmol"},{"issue":"6","key":"1286_CR44","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1097\/ICO.0b013e31823f8b0c","volume":"31","author":"EJ Holland","year":"2012","unstructured":"Holland EJ, Mogilishetty G, Skeens HM, et al. Systemic immunosuppression in ocular surface stem cell transplantation: results of a 10-year experience. Cornea. 2012;31(6):655\u201361. https:\/\/doi.org\/10.1097\/ICO.0b013e31823f8b0c.","journal-title":"Cornea"},{"issue":"7","key":"1286_CR45","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1016\/s0161-6420(02)01081-3","volume":"109","author":"L Ilari","year":"2002","unstructured":"Ilari L, Daya SM. Long-term outcomes of keratolimbal allograft for the treatment of severe ocular surface disorders. Ophthalmology. 2002;109(7):1278\u201384. https:\/\/doi.org\/10.1016\/s0161-6420(02)01081-3.","journal-title":"Ophthalmology"},{"issue":"11","key":"1286_CR46","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1001\/archophthalmol.2009.263","volume":"127","author":"L Liang","year":"2009","unstructured":"Liang L, Sheha H, Tseng SC. Long-term outcomes of keratolimbal allograft for total limbal stem cell deficiency using combined immunosuppressive agents and correction of ocular surface deficits. Arch Ophthalmol. 2009;127(11):1428\u201334. https:\/\/doi.org\/10.1001\/archophthalmol.2009.263.","journal-title":"Arch Ophthalmol"},{"issue":"11","key":"1286_CR47","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1007\/s00417-011-1760-3","volume":"249","author":"ES Han","year":"2011","unstructured":"Han ES, Wee WR, Lee JH, Kim MK. Long-term outcome and prognostic factor analysis for keratolimbal allografts. Graefes Arch Clin Exp Ophthalmol. 2011;249(11):1697\u2013704. https:\/\/doi.org\/10.1007\/s00417-011-1760-3.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"6","key":"1286_CR48","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1007\/s10792-016-0415-0","volume":"37","author":"JKS Parihar","year":"2017","unstructured":"Parihar JKS, Parihar AS, Jain VK, Kaushik J, Nath P. Allogenic cultivated limbal stem cell transplantation versus cadaveric keratolimbal allograft in ocular surface disorder: 1-year outcome. Int Ophthalmol. 2017;37(6):1323\u201331. https:\/\/doi.org\/10.1007\/s10792-016-0415-0.","journal-title":"Int Ophthalmol"},{"issue":"8","key":"1286_CR49","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1097\/ico.0000000000002329","volume":"39","author":"AY Cheung","year":"2020","unstructured":"Cheung AY, Eslani M, Kurji KH, et al. Long-term outcomes of living-related conjunctival limbal allograft compared with keratolimbal allograft in patients with limbal stem cell deficiency. Cornea. 2020;39(8):980\u20135. https:\/\/doi.org\/10.1097\/ico.0000000000002329.","journal-title":"Cornea"},{"issue":"11","key":"1286_CR50","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1097\/ico.0000000000001331","volume":"36","author":"L Sepsakos","year":"2017","unstructured":"Sepsakos L, Cheung AY, Nerad JA, Mogilishetty G, Holland EJ. Donor-derived conjunctival-limbal melanoma after a keratolimbal allograft. Cornea. 2017;36(11):1415\u20138. https:\/\/doi.org\/10.1097\/ico.0000000000001331.","journal-title":"Cornea"},{"key":"1286_CR51","unstructured":"Hjortdal J, Jones G. The European Eye Bank Association\u2014current standards and regulations. 2015. p. 19\u201326."},{"issue":"9","key":"1286_CR52","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/j.ophtha.2024.02.018","volume":"131","author":"JY Li","year":"2024","unstructured":"Li JY, Cortina MS, Greiner MA, et al. Outcomes and complications of limbal stem cell allograft transplantation: a report by the American Academy of Ophthalmology. Ophthalmology. 2024;131(9):1121\u201331. https:\/\/doi.org\/10.1016\/j.ophtha.2024.02.018.","journal-title":"Ophthalmology"},{"issue":"6","key":"1286_CR53","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1016\/s0161-6420(02)00960-0","volume":"109","author":"A Solomon","year":"2002","unstructured":"Solomon A, Ellies P, Anderson DF, Touhami A, Grueterich M, Espana EM, et al. Long-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency. Ophthalmology. 2002;109(6):1159\u201366. https:\/\/doi.org\/10.1016\/s0161-6420(02)00960-0.","journal-title":"Ophthalmology"},{"issue":"4","key":"1286_CR54","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1097\/01.ico.0000176608.65708.27","volume":"25","author":"F Maruyama-Hosoi","year":"2006","unstructured":"Maruyama-Hosoi F, Shimazaki J, Shimmura S, Tsubota K. Changes observed in keratolimbal allograft. Cornea. 2006;25(4):377\u201382. https:\/\/doi.org\/10.1097\/01.ico.0000176608.65708.27.","journal-title":"Cornea"},{"issue":"11","key":"1286_CR55","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1097\/ICO.0b013e31823f8e95","volume":"31","author":"CC Chan","year":"2012","unstructured":"Chan CC, Biber JM, Holland EJ. The modified Cincinnati procedure: combined conjunctival limbal autografts and keratolimbal allografts for severe unilateral ocular surface failure. Cornea. 2012;31(11):1264\u201372. https:\/\/doi.org\/10.1097\/ICO.0b013e31823f8e95.","journal-title":"Cornea"},{"key":"1286_CR56","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.986194","volume":"9","author":"Z Li","year":"2022","unstructured":"Li Z, Yang K, Zhou Y, Wu T, Zhang H, Yang Q, et al. Outcome of keratolimbal allograft transplantation with deep anterior lamellar keratoplasty for bilateral limbal stem cell deficiency. Front Med Lausanne. 2022;9:986194. https:\/\/doi.org\/10.3389\/fmed.2022.986194.","journal-title":"Front Med Lausanne"},{"issue":"1","key":"1286_CR57","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/s0161-6420(00)00475-9","volume":"108","author":"SM Daya","year":"2001","unstructured":"Daya SM, Ilari FA. Living related conjunctival limbal allograft for the treatment of stem cell deficiency. Ophthalmology. 2001;108(1):126\u201333. https:\/\/doi.org\/10.1016\/s0161-6420(00)00475-9.","journal-title":"Ophthalmology"},{"issue":"2","key":"1286_CR58","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.ajo.2005.03.022","volume":"140","author":"MS Santos","year":"2005","unstructured":"Santos MS, Gomes JA, Hofling-Lima AL, Rizzo LV, Romano AC, Belfort R Jr. Survival analysis of conjunctival limbal grafts and amniotic membrane transplantation in eyes with total limbal stem cell deficiency. Am J Ophthalmol. 2005;140(2):223\u201330. https:\/\/doi.org\/10.1016\/j.ajo.2005.03.022.","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"1286_CR59","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1590\/s0004-27492008000600003","volume":"71","author":"C Scocco","year":"2008","unstructured":"Scocco C, Kwitko S, Rymer S, Marinho D, Bocaccio F, Lindenmeyer R. HLA-matched living-related conjunctival limbal allograft for bilateral ocular surface disorders: long-term results. Arq Bras Oftalmol. 2008;71(6):781\u20137. https:\/\/doi.org\/10.1590\/s0004-27492008000600003.","journal-title":"Arq Bras Oftalmol"},{"issue":"10","key":"1286_CR60","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1001\/archophthalmol.2011.251","volume":"129","author":"T Huang","year":"2011","unstructured":"Huang T, Wang Y, Zhang H, Gao N, Hu A. Limbal allografting from living-related donors to treat partial limbal deficiency secondary to ocular chemical burns. Arch Ophthalmol. 2011;129(10):1267\u201373. https:\/\/doi.org\/10.1001\/archophthalmol.2011.251.","journal-title":"Arch Ophthalmol"},{"key":"1286_CR61","doi-asserted-by":"publisher","first-page":"383","DOI":"10.2147\/opth.S192316","volume":"13","author":"AH El-Hofi","year":"2019","unstructured":"El-Hofi AH, Helaly HA. Evaluation of limbal transplantation in eyes with bilateral severe ocular surface damage secondary to chemical injury. Clin Ophthalmol. 2019;13:383\u201390. https:\/\/doi.org\/10.2147\/opth.S192316.","journal-title":"Clin Ophthalmol"},{"issue":"9057","key":"1286_CR62","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1016\/s0140-6736(96)11188-0","volume":"349","author":"G Pellegrini","year":"1997","unstructured":"Pellegrini G, Traverso CE, Franzi AT, Zingirian M, Cancedda R, De Luca M. Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet. 1997;349(9057):990\u20133. https:\/\/doi.org\/10.1016\/s0140-6736(96)11188-0.","journal-title":"Lancet"},{"issue":"7","key":"1286_CR63","doi-asserted-by":"publisher","first-page":"4130","DOI":"10.1167\/iovs.12-9876","volume":"53","author":"J Liu","year":"2012","unstructured":"Liu J, Lawrence BD, Liu A, Schwab IR, Oliveira LA, Rosenblatt MI. Silk fibroin as a biomaterial substrate for corneal epithelial cell sheet generation. Invest Ophthalmol Vis Sci. 2012;53(7):4130\u20138. https:\/\/doi.org\/10.1167\/iovs.12-9876.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1286_CR64","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.exer.2014.07.024","volume":"127","author":"I Massie","year":"2014","unstructured":"Massie I, Levis HJ, Daniels JT. Response of human limbal epithelial cells to wounding on 3D RAFT tissue equivalents: effect of airlifting and human limbal fibroblasts. Exp Eye Res. 2014;127:196\u2013205. https:\/\/doi.org\/10.1016\/j.exer.2014.07.024.","journal-title":"Exp Eye Res"},{"key":"1286_CR65","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.jtos.2024.01.003","volume":"32","author":"S Kengpunpanich","year":"2024","unstructured":"Kengpunpanich S, Chirapapaisan C, Ngowyutagon P, Chotikavanich S, Sikarinkul R, Taetrongchit N, et al. Comparative analysis of long-term results of three epithelial cell transplantation procedures for treating limbal stem cell deficiency. Ocul Surf. 2024;32:71\u201380. https:\/\/doi.org\/10.1016\/j.jtos.2024.01.003.","journal-title":"Ocul Surf"},{"issue":"1","key":"1286_CR66","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1002\/sctm.17-0003","volume":"7","author":"G Pellegrini","year":"2018","unstructured":"Pellegrini G, Ardig\u00f2 D, Milazzo G, Iotti G, Guatelli P, Pelosi D, et al. Navigating market authorization: the path Holoclar took to become the first stem cell product approved in the European Union. Stem Cells Transl Med. 2018;7(1):146\u201354. https:\/\/doi.org\/10.1002\/sctm.17-0003.","journal-title":"Stem Cells Transl Med"},{"key":"1286_CR67","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24108926","author":"H Toshida","year":"2023","unstructured":"Toshida H, Kasahara T, Kiriyama M, et al. Early clinical outcomes of the first commercialized human autologous ex vivo cultivated oral mucosal epithelial cell transplantation for limbal stem cell deficiency: two case reports and literature review. Int J Mol Sci. 2023. https:\/\/doi.org\/10.3390\/ijms24108926.","journal-title":"Int J Mol Sci"},{"issue":"7","key":"1286_CR68","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1136\/bjophthalmol-2011-301164","volume":"96","author":"VS Sangwan","year":"2012","unstructured":"Sangwan VS, Basu S, MacNeil S, Balasubramanian D. Simple limbal epithelial transplantation (SLET): a novel surgical technique for the treatment of unilateral limbal stem cell deficiency. Br J Ophthalmol. 2012;96(7):931\u20134. https:\/\/doi.org\/10.1136\/bjophthalmol-2011-301164.","journal-title":"Br J Ophthalmol"},{"issue":"10","key":"1286_CR69","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1136\/bjophthalmol-2015-307348","volume":"100","author":"J Vazirani","year":"2016","unstructured":"Vazirani J, Ali MH, Sharma N, Gupta N, Mittal V, Atallah M, et al. Autologous simple limbal epithelial transplantation for unilateral limbal stem cell deficiency: multicentre results. Br J Ophthalmol. 2016;100(10):1416\u201320. https:\/\/doi.org\/10.1136\/bjophthalmol-2015-307348.","journal-title":"Br J Ophthalmol"},{"key":"1286_CR70","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-009051","author":"S Bhalekar","year":"2013","unstructured":"Bhalekar S, Basu S, Sangwan VS. Successful management of immunological rejection following allogeneic simple limbal epithelial transplantation (SLET) for bilateral ocular burns. BMJ Case Rep. 2013. https:\/\/doi.org\/10.1136\/bcr-2013-009051.","journal-title":"BMJ Case Rep"},{"issue":"8","key":"1286_CR71","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.4103\/ijo.IJO_117_19","volume":"67","author":"SS Shanbhag","year":"2019","unstructured":"Shanbhag SS, Patel CN, Goyal R, Donthineni PR, Singh V, Basu S. Simple limbal epithelial transplantation (SLET): review of indications, surgical technique, mechanism, outcomes, limitations, and impact. Indian J Ophthalmol. 2019;67(8):1265\u201377. https:\/\/doi.org\/10.4103\/ijo.IJO_117_19.","journal-title":"Indian J Ophthalmol"},{"issue":"6","key":"1286_CR72","doi-asserted-by":"publisher","first-page":"Nd06-7","DOI":"10.7860\/jcdr\/2016\/19306.7997","volume":"10","author":"SK Arya","year":"2016","unstructured":"Arya SK, Bhatti A, Raj A, Bamotra RK. Simple limbal epithelial transplantation in acid injury and severe dry eye. J Clin Diagn Res. 2016;10(6):Nd06-7. https:\/\/doi.org\/10.7860\/jcdr\/2016\/19306.7997.","journal-title":"J Clin Diagn Res"},{"issue":"7 Suppl","key":"1286_CR73","doi-asserted-by":"publisher","first-page":"S75","DOI":"10.1097\/00003226-200310001-00011","volume":"22","author":"T Nakamura","year":"2003","unstructured":"Nakamura T, Kinoshita S. Ocular surface reconstruction using cultivated mucosal epithelial stem cells. Cornea. 2003;22(7 Suppl):S75-80. https:\/\/doi.org\/10.1097\/00003226-200310001-00011.","journal-title":"Cornea"},{"issue":"12","key":"1286_CR74","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1056\/NEJMoa040455","volume":"351","author":"K Nishida","year":"2004","unstructured":"Nishida K, Yamato M, Hayashida Y, Watanabe K, Yamamoto K, Adachi E, et al. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl J Med. 2004;351(12):1187\u201396. https:\/\/doi.org\/10.1056\/NEJMoa040455.","journal-title":"N Engl J Med"},{"issue":"10","key":"1286_CR75","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1136\/bjo.2003.038497","volume":"88","author":"T Nakamura","year":"2004","unstructured":"Nakamura T, Inatomi T, Sotozono C, Amemiya T, Kanamura N, Kinoshita S. Transplantation of cultivated autologous oral mucosal epithelial cells in patients with severe ocular surface disorders. Br J Ophthalmol. 2004;88(10):1280\u20134. https:\/\/doi.org\/10.1136\/bjo.2003.038497.","journal-title":"Br J Ophthalmol"},{"issue":"9","key":"1286_CR76","doi-asserted-by":"publisher","first-page":"5615","DOI":"10.1167\/iovs.11-9293","volume":"53","author":"HC Chen","year":"2012","unstructured":"Chen HC, Yeh LK, Tsai YJ, Chen H-C, Lai C-H, Chen C-C, et al. Expression of angiogenesis-related factors in human corneas after cultivated oral mucosal epithelial transplantation. Invest Ophthalmol Vis Sci. 2012;53(9):5615\u201323. https:\/\/doi.org\/10.1167\/iovs.11-9293.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1286_CR77","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241411522","author":"E Attico","year":"2023","unstructured":"Attico E, Galaverni G, Torello A, et al. Comparison between cultivated oral mucosa and ocular surface epithelia for COMET patients follow-up. Int J Mol Sci. 2023. https:\/\/doi.org\/10.3390\/ijms241411522.","journal-title":"Int J Mol Sci"},{"issue":"1","key":"1286_CR78","doi-asserted-by":"publisher","first-page":"18088","DOI":"10.1038\/s41598-019-54571-7","volume":"9","author":"A Inamochi","year":"2019","unstructured":"Inamochi A, Tomioka A, Kitamoto K, et al. Simple oral mucosal epithelial transplantation in a rabbit model. Sci Rep. 2019;9(1):18088. https:\/\/doi.org\/10.1038\/s41598-019-54571-7.","journal-title":"Sci Rep"},{"key":"1286_CR79","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2023.108643","volume":"110","author":"MB Doctor","year":"2023","unstructured":"Doctor MB, Rajagopal RN, Basu S. Simple oral mucosal epithelial transplantation (SOMET) for ocular surface reconstruction in Stevens\u2013Johnson syndrome: a case report. Int J Surg Case Rep. 2023;110:108643. https:\/\/doi.org\/10.1016\/j.ijscr.2023.108643.","journal-title":"Int J Surg Case Rep"},{"issue":"8","key":"1286_CR80","first-page":"2244","volume":"32","author":"Y Komai","year":"1991","unstructured":"Komai Y, Ushiki T. The three-dimensional organization of collagen fibrils in the human cornea and sclera. Invest Ophthalmol Vis Sci. 1991;32(8):2244\u201358.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1286_CR81","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.exer.2014.08.001","volume":"133","author":"S Chen","year":"2015","unstructured":"Chen S, Mienaltowski MJ, Birk DE. Regulation of corneal stroma extracellular matrix assembly. Exp Eye Res. 2015;133:69\u201380. https:\/\/doi.org\/10.1016\/j.exer.2014.08.001.","journal-title":"Exp Eye Res"},{"issue":"3","key":"1286_CR82","first-page":"644","volume":"39","author":"A Daxer","year":"1998","unstructured":"Daxer A, Misof K, Grabner B, Ettl A, Fratzl P. Collagen fibrils in the human corneal stroma: structure and aging. Invest Ophthalmol Vis Sci. 1998;39(3):644\u20138.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1286_CR83","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12030649","author":"C Chandran","year":"2024","unstructured":"Chandran C, Santra M, Rubin E, Geary ML, Yam GH. Regenerative therapy for corneal scarring disorders. Biomedicines. 2024. https:\/\/doi.org\/10.3390\/biomedicines12030649.","journal-title":"Biomedicines"},{"issue":"11","key":"1286_CR84","doi-asserted-by":"publisher","first-page":"3806","DOI":"10.1016\/j.celrep.2020.02.062","volume":"30","author":"JH Ko","year":"2020","unstructured":"Ko JH, Kim HJ, Jeong HJ, Lee HJ, Oh JY. Mesenchymal stem and stromal cells harness macrophage-derived amphiregulin to maintain tissue homeostasis. Cell Rep. 2020;30(11):3806-20.e6. https:\/\/doi.org\/10.1016\/j.celrep.2020.02.062.","journal-title":"Cell Rep"},{"issue":"266","key":"1286_CR85","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3009644","volume":"6","author":"S Basu","year":"2014","unstructured":"Basu S, Hertsenberg AJ, Funderburgh ML, et al. Human limbal biopsy-derived stromal stem cells prevent corneal scarring. Sci Transl Med. 2014;6(266):266ra172. https:\/\/doi.org\/10.1126\/scitranslmed.3009644.","journal-title":"Sci Transl Med"},{"issue":"6","key":"1286_CR86","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/j.jcrs.2014.04.013","volume":"40","author":"CJ Roberts","year":"2014","unstructured":"Roberts CJ, Dupps WJ. Biomechanics of corneal ectasia and biomechanical treatments. J Cataract Refract Surg. 2014;40(6):991\u20138. https:\/\/doi.org\/10.1016\/j.jcrs.2014.04.013.","journal-title":"J Cataract Refract Surg"},{"issue":"11","key":"1286_CR87","doi-asserted-by":"publisher","first-page":"906","DOI":"10.3928\/1081597x-20100428-02","volume":"26","author":"R Ambr\u00f3sio Jr","year":"2010","unstructured":"Ambr\u00f3sio R Jr, Dawson DG, Salom\u00e3o M, Guerra FP, Caiado AL, Belin MW. Corneal ectasia after LASIK despite low preoperative risk: tomographic and biomechanical findings in the unoperated, stable, fellow eye. J Refract Surg. 2010;26(11):906\u201311. https:\/\/doi.org\/10.3928\/1081597x-20100428-02.","journal-title":"J Refract Surg"},{"key":"1286_CR88","doi-asserted-by":"publisher","DOI":"10.3390\/vision7010022","author":"Z Ashena","year":"2023","unstructured":"Ashena Z, Niestrata M, Tavassoli S. Management of stromal corneal dystrophies; review of the literature with a focus on phototherapeutic keratectomy and keratoplasty. Vision. 2023. https:\/\/doi.org\/10.3390\/vision7010022.","journal-title":"Vision"},{"issue":"8","key":"1286_CR89","doi-asserted-by":"publisher","first-page":"465","DOI":"10.4103\/0301-4738.116061","volume":"61","author":"R Fogla","year":"2013","unstructured":"Fogla R. Deep anterior lamellar keratoplasty in the management of keratoconus. Indian J Ophthalmol. 2013;61(8):465\u20138. https:\/\/doi.org\/10.4103\/0301-4738.116061.","journal-title":"Indian J Ophthalmol"},{"key":"1286_CR90","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.ajo.2015.11.018","volume":"162","author":"S Feizi","year":"2016","unstructured":"Feizi S, Javadi MA, Mohammad-Rabei H. An analysis of factors influencing quality of vision after Big-Bubble deep anterior lamellar keratoplasty in Keratoconus. Am J Ophthalmol. 2016;162:66-73.e2. https:\/\/doi.org\/10.1016\/j.ajo.2015.11.018.","journal-title":"Am J Ophthalmol"},{"issue":"5-6","key":"1286_CR91","doi-asserted-by":"publisher","first-page":"281","DOI":"10.3109\/08820538.2013.825283","volume":"28","author":"CE Hamill","year":"2013","unstructured":"Hamill CE, Schmedt T, Jurkunas U. Fuchs endothelial cornea dystrophy: a review of the genetics behind disease development. Semin Ophthalmol. 2013;28(5\u20136):281\u20136. https:\/\/doi.org\/10.3109\/08820538.2013.825283.","journal-title":"Semin Ophthalmol"},{"key":"1286_CR92","first-page":"295","volume":"25","author":"GG Nanda","year":"2019","unstructured":"Nanda GG, Alone DP. Review: current understanding of the pathogenesis of Fuchs\u2019 endothelial corneal dystrophy. Mol Vis. 2019;25:295\u2013310.","journal-title":"Mol Vis"},{"issue":"11","key":"1286_CR93","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1097\/ico.0000000000003446","volume":"43","author":"MO Price","year":"2024","unstructured":"Price MO, Kanapka L, Kollman C, Lass JH, Price FW Jr. Descemet membrane endothelial keratoplasty: 10-year cell loss and failure rate compared with Descemet stripping endothelial keratoplasty and penetrating keratoplasty. Cornea. 2024;43(11):1403\u20139. https:\/\/doi.org\/10.1097\/ico.0000000000003446.","journal-title":"Cornea"},{"issue":"1","key":"1286_CR94","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.1038\/s41598-023-29659-w","volume":"13","author":"H Wajima","year":"2023","unstructured":"Wajima H, Hayashi T, Kobayashi A, et al. Graft rejection episodes after keratoplasty in Japanese eyes. Sci Rep. 2023;13(1):2635. https:\/\/doi.org\/10.1038\/s41598-023-29659-w.","journal-title":"Sci Rep"},{"issue":"6","key":"1286_CR95","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1016\/j.ophtha.2012.11.030","volume":"120","author":"M Busin","year":"2013","unstructured":"Busin M, Madi S, Santorum P, Scorcia V, Beltz J. Ultrathin Descemet\u2019s stripping automated endothelial keratoplasty with the microkeratome double-pass technique: two-year outcomes. Ophthalmology. 2013;120(6):1186\u201394. https:\/\/doi.org\/10.1016\/j.ophtha.2012.11.030.","journal-title":"Ophthalmology"},{"issue":"11","key":"1286_CR96","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1016\/j.ophtha.2016.07.036","volume":"123","author":"MM Dickman","year":"2016","unstructured":"Dickman MM, Kruit PJ, Remeijer L, et al. A randomized multicenter clinical trial of ultrathin Descemet stripping automated endothelial keratoplasty (DSAEK) versus DSAEK. Ophthalmology. 2016;123(11):2276\u201384. https:\/\/doi.org\/10.1016\/j.ophtha.2016.07.036.","journal-title":"Ophthalmology"},{"issue":"9","key":"1286_CR97","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/j.ophtha.2020.02.029","volume":"127","author":"SL Dunker","year":"2020","unstructured":"Dunker SL, Dickman MM, Wisse RPL, et al. Descemet membrane endothelial keratoplasty versus ultrathin Descemet stripping automated endothelial keratoplasty: a multicenter randomized controlled clinical trial. Ophthalmology. 2020;127(9):1152\u20139. https:\/\/doi.org\/10.1016\/j.ophtha.2020.02.029.","journal-title":"Ophthalmology"},{"issue":"5","key":"1286_CR98","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1097\/ico.0000000000001510","volume":"37","author":"AY Cheung","year":"2018","unstructured":"Cheung AY, Hou JH, Bedard P, et al. Technique for preparing ultrathin and nanothin Descemet stripping automated endothelial keratoplasty tissue. Cornea. 2018;37(5):661\u20136. https:\/\/doi.org\/10.1097\/ico.0000000000001510.","journal-title":"Cornea"},{"issue":"10","key":"1286_CR99","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1097\/ico.0000000000001697","volume":"37","author":"KH Kurji","year":"2018","unstructured":"Kurji KH, Cheung AY, Eslani M, et al. Comparison of visual acuity outcomes between nanothin Descemet stripping automated endothelial keratoplasty and Descemet membrane endothelial keratoplasty. Cornea. 2018;37(10):1226\u201331. https:\/\/doi.org\/10.1097\/ico.0000000000001697.","journal-title":"Cornea"},{"issue":"3","key":"1286_CR100","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1016\/j.ophtha.2011.08.034","volume":"119","author":"M Rudolph","year":"2012","unstructured":"Rudolph M, Laaser K, Bachmann BO, Cursiefen C, Epstein D, Kruse FE. Corneal higher-order aberrations after Descemet\u2019s membrane endothelial keratoplasty. Ophthalmology. 2012;119(3):528\u201335. https:\/\/doi.org\/10.1016\/j.ophtha.2011.08.034.","journal-title":"Ophthalmology"},{"issue":"1","key":"1286_CR101","doi-asserted-by":"publisher","DOI":"10.1186\/s40662-020-00191-6","volume":"7","author":"R Mencucci","year":"2020","unstructured":"Mencucci R, Favuzza E, Marziali E, Cennamo M, Mazzotta C, Lucenteforte E, et al. Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison. Eye Vis. 2020;7(1):25. https:\/\/doi.org\/10.1186\/s40662-020-00191-6.","journal-title":"Eye Vis"},{"key":"1286_CR102","doi-asserted-by":"publisher","DOI":"10.1055\/a-2558-2583","author":"T Berger","year":"2025","unstructured":"Berger T, Seitz B, Suffo S, Gvozdenovic R, Abu Dail Y, Daas L. Fellow eye comparison of tomographic parameters and higher-order aberrations in ultrathin Descemet stripping automated endothelial keratoplasty and Descemet membrane endothelial keratoplasty. Klin Monatsbl Augenheilkd. 2025. https:\/\/doi.org\/10.1055\/a-2558-2583.","journal-title":"Klin Monatsbl Augenheilkd"},{"issue":"7","key":"1286_CR103","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1016\/j.ophtha.2019.02.007","volume":"126","author":"MJ Duggan","year":"2019","unstructured":"Duggan MJ, Rose-Nussbaumer J, Lin CC, Austin A, Labadzinzki PC, Chamberlain WD. Corneal higher-order aberrations in Descemet membrane endothelial keratoplasty versus ultrathin DSAEK in the Descemet endothelial thickness comparison trial: a randomized clinical trial. Ophthalmology. 2019;126(7):946\u201357. https:\/\/doi.org\/10.1016\/j.ophtha.2019.02.007.","journal-title":"Ophthalmology"},{"key":"1286_CR104","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10215119","author":"A Machali\u0144ska","year":"2021","unstructured":"Machali\u0144ska A, Kuligowska A, Kowalska B, Safranow K. Comparative analysis of corneal parameters in swept-source imaging between DMEK and UT-DSAEK eyes. J Clin Med. 2021. https:\/\/doi.org\/10.3390\/jcm10215119.","journal-title":"J Clin Med"},{"key":"1286_CR105","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10030419","author":"J Torras-Sanvicens","year":"2021","unstructured":"Torras-Sanvicens J, Blanco-Dom\u00ednguez I, S\u00e1nchez-Gonz\u00e1lez JM, et al. Visual quality and subjective satisfaction in ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) versus Descemet membrane endothelial keratoplasty (DMEK): a fellow-eye comparison. J Clin Med. 2021. https:\/\/doi.org\/10.3390\/jcm10030419.","journal-title":"J Clin Med"},{"key":"1286_CR106","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.ajo.2022.09.013","volume":"245","author":"AB Maier","year":"2023","unstructured":"Maier AB, Milek J, Joussen AM, Dietrich-Ntoukas T, Lichtner G. Systematic review and meta-analysis: outcomes after Descemet membrane endothelial keratoplasty versus ultrathin Descemet stripping automated endothelial keratoplasty. Am J Ophthalmol. 2023;245:222\u201332. https:\/\/doi.org\/10.1016\/j.ajo.2022.09.013.","journal-title":"Am J Ophthalmol"},{"issue":"8","key":"1286_CR107","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1097\/01.ico.0000248385.16896.34","volume":"25","author":"GR Melles","year":"2006","unstructured":"Melles GR, Ong TS, Ververs B, van der Wees J. Descemet membrane endothelial keratoplasty (DMEK). Cornea. 2006;25(8):987\u201390. https:\/\/doi.org\/10.1097\/01.ico.0000248385.16896.34.","journal-title":"Cornea"},{"issue":"3","key":"1286_CR108","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1097\/ico.0000000000001111","volume":"36","author":"L Baydoun","year":"2017","unstructured":"Baydoun L, M\u00fcller T, Lavy I, Parker J, Rodriguez-Calvo-de-Mora M, Liarakos VS, et al. Ten-year clinical outcome of the first patient undergoing Descemet membrane endothelial keratoplasty. Cornea. 2017;36(3):379\u201381. https:\/\/doi.org\/10.1097\/ico.0000000000001111.","journal-title":"Cornea"},{"issue":"14","key":"1286_CR109","doi-asserted-by":"publisher","first-page":"3026","DOI":"10.1038\/s41433-023-02467-2","volume":"37","author":"DJ Hurley","year":"2023","unstructured":"Hurley DJ, Murtagh P, Guerin M. Ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) versus Descemet membrane endothelial keratoplasty (DMEK)-a systematic review and meta-analysis. Eye (Lond). 2023;37(14):3026\u201332. https:\/\/doi.org\/10.1038\/s41433-023-02467-2.","journal-title":"Eye (Lond)"},{"issue":"12","key":"1286_CR110","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1097\/ico.0000000000002806","volume":"40","author":"GU Auffarth","year":"2021","unstructured":"Auffarth GU, Son HS, Koch M, Weindler J, Merz P, Daphna O, et al. Implantation of an artificial endothelial layer for treatment of chronic corneal edema. Cornea. 2021;40(12):1633\u20138. https:\/\/doi.org\/10.1097\/ico.0000000000002806.","journal-title":"Cornea"},{"key":"1286_CR111","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13216520","author":"D Romano","year":"2024","unstructured":"Romano D, Ventura M, Vaccaro S, et al. Corneal artificial endothelial layer (EndoArt): literature review and our experience. J Clin Med. 2024. https:\/\/doi.org\/10.3390\/jcm13216520.","journal-title":"J Clin Med"},{"issue":"9","key":"1286_CR112","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1097\/ico.0000000000003433","volume":"43","author":"L Fontana","year":"2024","unstructured":"Fontana L, di Geronimo N, Cennamo M, Mencucci R, Versura P, Moramarco A. Early outcomes of an artificial endothelial replacement membrane implantation after failed repeat endothelial keratoplasty. Cornea. 2024;43(9):1088\u201394. https:\/\/doi.org\/10.1097\/ico.0000000000003433.","journal-title":"Cornea"},{"issue":"10","key":"1286_CR113","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1097\/ico.0000000000003734","volume":"44","author":"O Daphna","year":"2025","unstructured":"Daphna O, Auffarth GU, Lapid-Gortzak R, Chaurasia S, Gilboa E, Lemze A, et al. A novel artificial endothelial replacement membrane for the treatment of chronic corneal edema. Cornea. 2025;44(10):1240\u20137. https:\/\/doi.org\/10.1097\/ico.0000000000003734.","journal-title":"Cornea"},{"issue":"4","key":"1286_CR114","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1055\/a-2479-8606","volume":"242","author":"R Lapid-Gortzak","year":"2025","unstructured":"Lapid-Gortzak R, van der Meulen I. 4.5-year follow-up with a novel corneal endothelial prosthesis. Klin Monatsbl Augenheilkd. 2025;242(4):318\u201323. https:\/\/doi.org\/10.1055\/a-2479-8606.","journal-title":"Klin Monatsbl Augenheilkd"},{"issue":"9","key":"1286_CR115","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1097\/ico.0000000000002975","volume":"41","author":"N Din","year":"2022","unstructured":"Din N, Cohen E, Popovic M, et al. Surgical management of Fuchs endothelial corneal dystrophy: a treatment algorithm and individual patient meta-analysis of Descemet stripping only. Cornea. 2022;41(9):1188\u201395. https:\/\/doi.org\/10.1097\/ico.0000000000002975.","journal-title":"Cornea"},{"issue":"7","key":"1286_CR116","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1097\/ico.0000000000002855","volume":"41","author":"A Franceschino","year":"2022","unstructured":"Franceschino A, Dutheil F, Pereira B, Watson SL, Chiambaretta F, Navel V. Descemetorhexis without endothelial keratoplasty in Fuchs endothelial corneal dystrophy: a systematic review and meta-analysis. Cornea. 2022;41(7):815\u201325. https:\/\/doi.org\/10.1097\/ico.0000000000002855.","journal-title":"Cornea"},{"issue":"12","key":"1286_CR117","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028310","volume":"6","author":"GS Peh","year":"2011","unstructured":"Peh GS, Toh KP, Wu FY, Tan DT, Mehta JS. Cultivation of human corneal endothelial cells isolated from paired donor corneas. PLoS ONE. 2011;6(12):e28310. https:\/\/doi.org\/10.1371\/journal.pone.0028310.","journal-title":"PLoS ONE"},{"issue":"10","key":"1286_CR118","doi-asserted-by":"publisher","first-page":"4519","DOI":"10.1167\/iovs.07-0567","volume":"48","author":"N Koizumi","year":"2007","unstructured":"Koizumi N, Sakamoto Y, Okumura N, Okahara N, Tsuchiya H, Torii R, et al. Cultivated corneal endothelial cell sheet transplantation in a primate model. Investig Ophthalmol Vis Sci. 2007;48(10):4519\u201326. https:\/\/doi.org\/10.1167\/iovs.07-0567.","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"11","key":"1286_CR119","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1056\/NEJMoa1712770","volume":"378","author":"S Kinoshita","year":"2018","unstructured":"Kinoshita S, Koizumi N, Ueno M, Okumura N, Imai K, Tanaka H, et al. Injection of cultured cells with a ROCK inhibitor for bullous keratopathy. N Engl J Med. 2018;378(11):995\u20131003. https:\/\/doi.org\/10.1056\/NEJMoa1712770.","journal-title":"N Engl J Med"},{"issue":"8","key":"1286_CR120","doi-asserted-by":"publisher","first-page":"3680","DOI":"10.1167\/iovs.08-2634","volume":"50","author":"N Okumura","year":"2009","unstructured":"Okumura N, Ueno M, Koizumi N, Sakamoto Y, Hirata K, Hamuro J, et al. Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor. Investig Ophthalmol Vis Sci. 2009;50(8):3680\u20137. https:\/\/doi.org\/10.1167\/iovs.08-2634.","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"1286_CR121","doi-asserted-by":"publisher","DOI":"10.1038\/srep26113","volume":"6","author":"N Okumura","year":"2016","unstructured":"Okumura N, Sakamoto Y, Fujii K, Kitano J, Nakano S, Tsujimoto Y, et al. Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction. Sci Rep. 2016;6:26113. https:\/\/doi.org\/10.1038\/srep26113.","journal-title":"Sci Rep"},{"issue":"4","key":"1286_CR122","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.ophtha.2020.09.002","volume":"128","author":"K Numa","year":"2021","unstructured":"Numa K, Imai K, Ueno M, Kitazawa K, Tanaka H, Bush JD, et al. Five-year follow-up of first 11 patients undergoing injection of cultured corneal endothelial cells for corneal endothelial failure. Ophthalmology. 2021;128(4):504\u201314. https:\/\/doi.org\/10.1016\/j.ophtha.2020.09.002.","journal-title":"Ophthalmology"},{"issue":"10","key":"1286_CR123","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1016\/j.ophtha.2025.05.020","volume":"132","author":"S Kinoshita","year":"2025","unstructured":"Kinoshita S, Ueno M, Toda M, Imai K, Tomioka Y, Numa K, et al. Long-term corneal rejuvenation after transplantation of cultured human corneal endothelial cells. Ophthalmology. 2025;132(10):1105\u201313. https:\/\/doi.org\/10.1016\/j.ophtha.2025.05.020.","journal-title":"Ophthalmology"},{"issue":"11","key":"1286_CR124","doi-asserted-by":"publisher","first-page":"8138","DOI":"10.1167\/iovs.11-8140","volume":"52","author":"TJ Echevarria","year":"2011","unstructured":"Echevarria TJ, Chow S, Watson S, Wakefield D, Di Girolamo N. Vitronectin: a matrix support factor for human limbal epithelial progenitor cells. Investig Ophthalmol Vis Sci. 2011;52(11):8138\u201347. https:\/\/doi.org\/10.1167\/iovs.11-8140.","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"9","key":"1286_CR125","first-page":"4128","volume":"60","author":"JH Hou","year":"2019","unstructured":"Hou JH, Bedard P, Lee S, Yuan C. Ex vivo expansion of limbal stem cells using Descemet\u2019s membrane as a culture substrate. Investig Ophthalmol Vis Sci. 2019;60(9):4128.","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"1","key":"1286_CR126","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1097\/ico.0000000000003565","volume":"44","author":"AY Cheung","year":"2025","unstructured":"Cheung AY, Reinisch CB, Hou JH. Decellularized Descemet membrane anterior keratoplasty with allogeneic simple limbal epithelial transplantation for partial limbal stem cell deficiency following partial keratolimbal allograft failure. Cornea. 2025;44(1):108\u201312. https:\/\/doi.org\/10.1097\/ico.0000000000003565.","journal-title":"Cornea"},{"issue":"1","key":"1286_CR127","doi-asserted-by":"publisher","DOI":"10.1186\/1478-811x-9-12","volume":"9","author":"R Hass","year":"2011","unstructured":"Hass R, Kasper C, B\u00f6hm S, Jacobs R. Different populations and sources of human mesenchymal stem cells (MSC): a comparison of adult and neonatal tissue-derived MSC. Cell Commun Signal. 2011;9(1):12. https:\/\/doi.org\/10.1186\/1478-811x-9-12.","journal-title":"Cell Commun Signal"},{"key":"1286_CR128","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241310917","author":"B Bhujel","year":"2023","unstructured":"Bhujel B, Oh SH, Kim CM, et al. Mesenchymal stem cells and exosomes: a novel therapeutic approach for corneal diseases. Int J Mol Sci. 2023. https:\/\/doi.org\/10.3390\/ijms241310917.","journal-title":"Int J Mol Sci"},{"key":"1286_CR129","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26020695","author":"MP De Miguel","year":"2025","unstructured":"De Miguel MP, Cadenas-Martin M, Stokking M, Martin-Gonzalez AI. Biomedical application of MSCs in corneal regeneration and repair. Int J Mol Sci. 2025. https:\/\/doi.org\/10.3390\/ijms26020695.","journal-title":"Int J Mol Sci"},{"key":"1286_CR130","doi-asserted-by":"publisher","DOI":"10.3390\/ijms252011121","author":"N Kobal","year":"2024","unstructured":"Kobal N, Marzidov\u0161ek M, Schollmayer P, Mali\u010dev E, Hawlina M, Marzidov\u0161ek ZL. Molecular and cellular mechanisms of the therapeutic effect of mesenchymal stem cells and extracellular vesicles in corneal regeneration. Int J Mol Sci. 2024. https:\/\/doi.org\/10.3390\/ijms252011121.","journal-title":"Int J Mol Sci"},{"key":"1286_CR131","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.trsl.2018.11.003","volume":"206","author":"M Calonge","year":"2019","unstructured":"Calonge M, P\u00e9rez I, Galindo S, et al. A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency. Transl Res. 2019;206:18\u201340. https:\/\/doi.org\/10.1016\/j.trsl.2018.11.003.","journal-title":"Transl Res"},{"issue":"4","key":"1286_CR132","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1080\/02713683.2023.2297342","volume":"49","author":"A Boto de Los Bueis","year":"2024","unstructured":"Boto de Los Bueis A, Vidal Arranz C, Del Hierro-Zarzuelo A, et al. Long-term effects of adipose-derived stem cells for the treatment of bilateral limbal stem cell deficiency. Curr Eye Res. 2024;49(4):345\u201353. https:\/\/doi.org\/10.1080\/02713683.2023.2297342.","journal-title":"Curr Eye Res"},{"issue":"7594","key":"1286_CR133","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1038\/nature17000","volume":"531","author":"R Hayashi","year":"2016","unstructured":"Hayashi R, Ishikawa Y, Sasamoto Y, et al. Co-ordinated ocular development from human iPS cells and recovery of corneal function. Nature. 2016;531(7594):376\u201380. https:\/\/doi.org\/10.1038\/nature17000.","journal-title":"Nature"},{"issue":"4","key":"1286_CR134","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1038\/nprot.2017.007","volume":"12","author":"R Hayashi","year":"2017","unstructured":"Hayashi R, Ishikawa Y, Katori R, et al. Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. Nat Protoc. 2017;12(4):683\u201396. https:\/\/doi.org\/10.1038\/nprot.2017.007.","journal-title":"Nat Protoc"},{"issue":"1","key":"1286_CR135","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2302\/kjm.2023-0001-IR","volume":"73","author":"S Shimmura","year":"2024","unstructured":"Shimmura S, Inagaki E, Hirayama M, Hatou S. The cornea: an ideal tissue for regenerative medicine. Keio J Med. 2024;73(1):1\u20137. https:\/\/doi.org\/10.2302\/kjm.2023-0001-IR.","journal-title":"Keio J Med"},{"issue":"4","key":"1286_CR136","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/j.stem.2019.02.005","volume":"24","author":"H Xu","year":"2019","unstructured":"Xu H, Wang B, Ono M, et al. Targeted disruption of HLA genes via CRISPR-Cas9 generates iPSCs with enhanced immune compatibility. Cell Stem Cell. 2019;24(4):566-78.e7. https:\/\/doi.org\/10.1016\/j.stem.2019.02.005.","journal-title":"Cell Stem Cell"},{"issue":"1","key":"1286_CR137","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s13046-020-01584-0","volume":"39","author":"K Wuputra","year":"2020","unstructured":"Wuputra K, Ku CC, Wu DC, Lin YC, Saito S, Yokoyama KK. Prevention of tumor risk associated with the reprogramming of human pluripotent stem cells. J Exp Clin Cancer Res. 2020;39(1):100. https:\/\/doi.org\/10.1186\/s13046-020-01584-0.","journal-title":"J Exp Clin Cancer Res"},{"issue":"4","key":"1286_CR138","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1097\/icu.0000000000000385","volume":"28","author":"SM Daya","year":"2017","unstructured":"Daya SM. Conjunctival-limbal autograft. Curr Opin Ophthalmol. 2017;28(4):370\u20136. https:\/\/doi.org\/10.1097\/icu.0000000000000385.","journal-title":"Curr Opin Ophthalmol"},{"key":"1286_CR139","doi-asserted-by":"publisher","DOI":"10.3390\/cells12091280","author":"S Sarkar","year":"2023","unstructured":"Sarkar S, Panikker P, D\u2019Souza S, Shetty R, Mohan RR, Ghosh A. Corneal regeneration using gene therapy approaches. Cells. 2023. https:\/\/doi.org\/10.3390\/cells12091280.","journal-title":"Cells"},{"issue":"4","key":"1286_CR140","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1016\/j.bbrc.2007.07.114","volume":"361","author":"H Yu","year":"2007","unstructured":"Yu H, Wu J, Li H, Wang Z, Chen X, Tian Y, et al. Inhibition of corneal neovascularization by recombinant adenovirus-mediated sFlk-1 expression. Biochem Biophys Res Commun. 2007;361(4):946\u201352. https:\/\/doi.org\/10.1016\/j.bbrc.2007.07.114.","journal-title":"Biochem Biophys Res Commun"},{"issue":"5","key":"1286_CR141","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1016\/j.exer.2009.06.021","volume":"89","author":"CN Kuo","year":"2009","unstructured":"Kuo CN, Yang LC, Yang CT, et al. Inhibition of corneal neovascularization with plasmid pigment epithelium-derived factor (p-PEDF) delivered by synthetic amphiphile INTeraction-18 (SAINT-18) vector in an experimental model of rat corneal angiogenesis. Exp Eye Res. 2009;89(5):678\u201385. https:\/\/doi.org\/10.1016\/j.exer.2009.06.021.","journal-title":"Exp Eye Res"},{"issue":"5","key":"1286_CR142","doi-asserted-by":"publisher","first-page":"3352","DOI":"10.1167\/iovs.13-12957","volume":"55","author":"DG Courtney","year":"2014","unstructured":"Courtney DG, Atkinson SD, Allen EH, et al. siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann\u2019s epithelial corneal dystrophy. Invest Ophthalmol Vis Sci. 2014;55(5):3352\u201360. https:\/\/doi.org\/10.1167\/iovs.13-12957.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"11","key":"1286_CR143","doi-asserted-by":"publisher","first-page":"3051","DOI":"10.1007\/s00417-023-06064-7","volume":"261","author":"R Shetty","year":"2023","unstructured":"Shetty R, Mahendran K, Joshi PD, Jeyabalan N, Jayadev C, Das D. Corneal stromal regeneration-keratoconus cell therapy: a review. Graefes Arch Clin Exp Ophthalmol. 2023;261(11):3051\u201365. https:\/\/doi.org\/10.1007\/s00417-023-06064-7.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"1286_CR144","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23136980","author":"V Jhanji","year":"2022","unstructured":"Jhanji V, Santra M, Riau AK, et al. Combined therapy using human corneal stromal stem cells and quiescent keratocytes to prevent corneal scarring after injury. Int J Mol Sci. 2022. https:\/\/doi.org\/10.3390\/ijms23136980.","journal-title":"Int J Mol Sci"},{"issue":"8","key":"1286_CR145","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1002\/sctm.19-0306","volume":"9","author":"D Ghoubay","year":"2020","unstructured":"Ghoubay D, Borderie M, Grieve K, Martos R, Bocheux R, Nguyen T-M, et al. Corneal stromal stem cells restore transparency after N(2) injury in mice. Stem Cells Transl Med. 2020;9(8):917\u201335. https:\/\/doi.org\/10.1002\/sctm.19-0306.","journal-title":"Stem Cells Transl Med"},{"issue":"1","key":"1286_CR146","doi-asserted-by":"publisher","DOI":"10.1186\/s40662-018-0122-1","volume":"5","author":"JL Ali\u00f3 Del Barrio","year":"2018","unstructured":"Ali\u00f3 Del Barrio JL, Ali\u00f3 JL. Cellular therapy of the corneal stroma: a new type of corneal surgery for keratoconus and corneal dystrophies. Eye Vis. 2018;5(1):28. https:\/\/doi.org\/10.1186\/s40662-018-0122-1.","journal-title":"Eye Vis"},{"key":"1286_CR147","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2020.108270","volume":"200","author":"I Khandaker","year":"2020","unstructured":"Khandaker I, Funderburgh JL, Geary ML, et al. A novel transgenic mouse model for corneal scar visualization. Exp Eye Res. 2020;200:108270. https:\/\/doi.org\/10.1016\/j.exer.2020.108270.","journal-title":"Exp Eye Res"},{"issue":"5","key":"1286_CR148","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1111\/j.1582-4934.2011.01418.x","volume":"16","author":"H Liu","year":"2012","unstructured":"Liu H, Zhang J, Liu CY, Hayashi Y, Kao WW. Bone marrow mesenchymal stem cells can differentiate and assume corneal keratocyte phenotype. J Cell Mol Med. 2012;16(5):1114\u201324. https:\/\/doi.org\/10.1111\/j.1582-4934.2011.01418.x.","journal-title":"J Cell Mol Med"},{"issue":"10","key":"1286_CR149","doi-asserted-by":"publisher","first-page":"2116","DOI":"10.1002\/stem.1481","volume":"31","author":"VJ Coulson-Thomas","year":"2013","unstructured":"Coulson-Thomas VJ, Caterson B, Kao WW. Transplantation of human umbilical mesenchymal stem cells cures the corneal defects of mucopolysaccharidosis VII mice. Stem Cells. 2013;31(10):2116\u201326. https:\/\/doi.org\/10.1002\/stem.1481.","journal-title":"Stem Cells"},{"key":"1286_CR150","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0000000000001010","author":"WW Kao","year":"2016","unstructured":"Kao WW, Coulson-Thomas VJ. Cell therapy of corneal diseases. Cornea. 2016. https:\/\/doi.org\/10.1097\/ico.0000000000001010.","journal-title":"Cornea"},{"key":"1286_CR151","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.exer.2015.01.020","volume":"132","author":"JL del Alio Barrio","year":"2015","unstructured":"del Alio Barrio JL, Chiesa M, Garagorri N, et al. Acellular human corneal matrix sheets seeded with human adipose-derived mesenchymal stem cells integrate functionally in an experimental animal model. Exp Eye Res. 2015;132:91\u2013100. https:\/\/doi.org\/10.1016\/j.exer.2015.01.020.","journal-title":"Exp Eye Res"},{"issue":"8","key":"1286_CR152","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1097\/ico.0000000000001228","volume":"36","author":"JL Ali\u00f3 Del Barrio","year":"2017","unstructured":"Ali\u00f3 Del Barrio JL, El Zarif M, de Miguel MP, et al. Cellular therapy with human autologous adipose-derived adult stem cells for advanced Keratoconus. Cornea. 2017;36(8):952\u201360. https:\/\/doi.org\/10.1097\/ico.0000000000001228.","journal-title":"Cornea"},{"key":"1286_CR153","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.ajo.2019.02.009","volume":"203","author":"JL Ali\u00f3","year":"2019","unstructured":"Ali\u00f3 JL, Ali\u00f3 Del Barrio JL, El Zarif M, Azaar A, Makdissy N, Khalil C, et al. Regenerative surgery of the corneal stroma for advanced keratoconus: 1-year outcomes. Am J Ophthalmol. 2019;203:53\u201368. https:\/\/doi.org\/10.1016\/j.ajo.2019.02.009.","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"1286_CR154","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1167\/iovs.61.4.22","volume":"61","author":"M El Zarif","year":"2020","unstructured":"El Zarif M, Jawad KA, Ali\u00f3 Del Barrio JL, et al. Corneal stroma cell density evolution in keratoconus corneas following the implantation of adipose mesenchymal stem cells and corneal laminas: an in vivo confocal microscopy study. Investig Ophthalmol Vis Sci. 2020;61(4):22. https:\/\/doi.org\/10.1167\/iovs.61.4.22.","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"6","key":"1286_CR155","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1097\/ico.0000000000002646","volume":"40","author":"M El Zarif","year":"2021","unstructured":"El Zarif M, Ali\u00f3 JL, Ali\u00f3 Del Barrio JL, et al. Corneal stromal regeneration therapy for advanced Keratoconus: long-term outcomes at 3 years. Cornea. 2021;40(6):741\u201354. https:\/\/doi.org\/10.1097\/ico.0000000000002646.","journal-title":"Cornea"},{"key":"1286_CR156","unstructured":"National Research C, Institute of Medicine Committee on the B, Biomedical Applications of Stem Cell R. Stem cells and the future of regenerative medicine. Washington (DC): National Academies Press (US). Copyright 2002 by the National Academy of Sciences. All rights reserved.; 2002."},{"key":"1286_CR157","doi-asserted-by":"publisher","DOI":"10.1002\/biot.201700067","author":"Q Zhu","year":"2017","unstructured":"Zhu Q, Li M, Yan C, et al. Directed differentiation of human embryonic stem cells to neural crest stem cells, functional peripheral neurons, and corneal keratocytes. Biotechnol J. 2017. https:\/\/doi.org\/10.1002\/biot.201700067.","journal-title":"Biotechnol J"},{"key":"1286_CR158","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/7651_2015_231","volume":"1341","author":"AJ Hertsenberg","year":"2016","unstructured":"Hertsenberg AJ, Funderburgh JL. Generation of corneal keratocytes from human embryonic stem cells. Methods Mol Biol. 2016;1341:285\u201394. https:\/\/doi.org\/10.1007\/7651_2015_231.","journal-title":"Methods Mol Biol"},{"key":"1286_CR159","doi-asserted-by":"publisher","DOI":"10.1136\/bmjophth-2024-001828","author":"J Chen","year":"2024","unstructured":"Chen J, Ou Q, Liu Y, et al. Embryoid body-based differentiation of human-induced pluripotent stem cells into cells with a corneal stromal keratocyte phenotype. BMJ Open Ophthalmol. 2024. https:\/\/doi.org\/10.1136\/bmjophth-2024-001828.","journal-title":"BMJ Open Ophthalmol"},{"key":"1286_CR160","doi-asserted-by":"publisher","first-page":"41286","DOI":"10.1038\/srep41286","volume":"7","author":"JW Foster","year":"2017","unstructured":"Foster JW, Wahlin K, Adams SM, Birk DE, Zack DJ, Chakravarti S. Cornea organoids from human induced pluripotent stem cells. Sci Rep. 2017;7:41286. https:\/\/doi.org\/10.1038\/srep41286.","journal-title":"Sci Rep"},{"key":"1286_CR161","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1007\/978-1-0716-0599-8_5","volume":"2145","author":"JW Foster","year":"2020","unstructured":"Foster JW, Wahlin KJ, Chakravarti S. A guide to the development of human corneaorganoids from induced pluripotent stem cells in culture. Methods Mol Biol. 2020;2145:51\u20138. https:\/\/doi.org\/10.1007\/978-1-0716-0599-8_5.","journal-title":"Methods Mol Biol"},{"key":"1286_CR162","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.addr.2020.06.011","volume":"168","author":"W Yu","year":"2021","unstructured":"Yu W, Wu Z. Ocular delivery of CRISPR\/Cas genome editing components for treatment of eye diseases. Adv Drug Deliv Rev. 2021;168:181\u201395. https:\/\/doi.org\/10.1016\/j.addr.2020.06.011.","journal-title":"Adv Drug Deliv Rev"},{"issue":"2","key":"1286_CR163","doi-asserted-by":"publisher","first-page":"104","DOI":"10.2174\/1566523221666210423084233","volume":"22","author":"C Amador","year":"2022","unstructured":"Amador C, Shah R, Ghiam S, Kramerov AA, Ljubimov AV. Gene therapy in the anterior eye segment. Curr Gene Ther. 2022;22(2):104\u201331. https:\/\/doi.org\/10.2174\/1566523221666210423084233.","journal-title":"Curr Gene Ther"},{"issue":"1","key":"1286_CR164","doi-asserted-by":"publisher","first-page":"16713","DOI":"10.1038\/s41598-017-16308-2","volume":"7","author":"Y Taketani","year":"2017","unstructured":"Taketani Y, Kitamoto K, Sakisaka T, et al. Repair of the TGFBI gene in human corneal keratocytes derived from a granular corneal dystrophy patient via CRISPR\/Cas9-induced homology-directed repair. Sci Rep. 2017;7(1):16713. https:\/\/doi.org\/10.1038\/s41598-017-16308-2.","journal-title":"Sci Rep"},{"issue":"5","key":"1286_CR165","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1089\/scd.2012.0286","volume":"22","author":"S Hatou","year":"2013","unstructured":"Hatou S, Yoshida S, Higa K, Miyashita H, Inagaki E, Okano H, et al. Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt\/\u03b2-catenin signaling. Stem Cells Dev. 2013;22(5):828\u201339. https:\/\/doi.org\/10.1089\/scd.2012.0286.","journal-title":"Stem Cells Dev"},{"issue":"3","key":"1286_CR166","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1002\/sctm.16-0162","volume":"6","author":"E Inagaki","year":"2017","unstructured":"Inagaki E, Hatou S, Higa K, Yoshida S, Shibata S, Okano H, et al. Skin-derived precursors as a source of progenitors for corneal endothelial regeneration. Stem Cells Transl Med. 2017;6(3):788\u201398. https:\/\/doi.org\/10.1002\/sctm.16-0162.","journal-title":"Stem Cells Transl Med"},{"key":"1286_CR167","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.617724","volume":"9","author":"BM Bosch","year":"2021","unstructured":"Bosch BM, Salero E, N\u00fa\u00f1ez-Toldr\u00e0 R, Sabater AL, Gil FJ, Perez RA. Discovering the potential of dental pulp stem cells for corneal endothelial cell production: a proof of concept. Front Bioeng Biotechnol. 2021;9:617724. https:\/\/doi.org\/10.3389\/fbioe.2021.617724.","journal-title":"Front Bioeng Biotechnol"},{"issue":"5","key":"1286_CR168","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1007\/s12015-021-10249-0","volume":"18","author":"C Olszewski","year":"2022","unstructured":"Olszewski C, Maassen J, Guenther R, Skazik-Voogt C, Gutermuth A. Mechanotransductive differentiation of hair follicle stem cells derived from aged eyelid skin into corneal endothelial-like cells. Stem Cell Rev Rep. 2022;18(5):1668\u201385. https:\/\/doi.org\/10.1007\/s12015-021-10249-0.","journal-title":"Stem Cell Rev Rep"},{"issue":"16","key":"1286_CR169","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1089\/scd.2017.0297","volume":"27","author":"K Yamashita","year":"2018","unstructured":"Yamashita K, Inagaki E, Hatou S, Higa K, Ogawa A, Miyashita H, et al. Corneal endothelial regeneration using mesenchymal stem cells derived from human umbilical cord. Stem Cells Dev. 2018;27(16):1097\u2013108. https:\/\/doi.org\/10.1089\/scd.2017.0297.","journal-title":"Stem Cells Dev"},{"key":"1286_CR170","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232315408","author":"EA Ye","year":"2022","unstructured":"Ye EA, Chung HS, Park Y, et al. Induction of corneal endothelial-like cells from mesenchymal stem cells of the umbilical cord. Int J Mol Sci. 2022. https:\/\/doi.org\/10.3390\/ijms232315408.","journal-title":"Int J Mol Sci"},{"issue":"15","key":"1286_CR171","doi-asserted-by":"publisher","first-page":"6878","DOI":"10.1167\/iovs.16-20024","volume":"57","author":"JJ Zhao","year":"2016","unstructured":"Zhao JJ, Afshari NA. Generation of human corneal endothelial cells via in vitro ocular lineage restriction of pluripotent stem cells. Invest Ophthalmol Vis Sci. 2016;57(15):6878\u201384. https:\/\/doi.org\/10.1167\/iovs.16-20024.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"1286_CR172","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2024.101847","volume":"6","author":"M Hirayama","year":"2025","unstructured":"Hirayama M, Hatou S, Nomura M, Hokama R, Hirayama OI, Inagaki E, et al. A first-in-human clinical study of an allogenic iPSC-derived corneal endothelial cell substitute transplantation for bullous keratopathy. Cell Rep Med. 2025;6(1):101847. https:\/\/doi.org\/10.1016\/j.xcrm.2024.101847.","journal-title":"Cell Rep Med"},{"issue":"1","key":"1286_CR173","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1186\/s13287-018-1036-5","volume":"9","author":"K Chakrabarty","year":"2018","unstructured":"Chakrabarty K, Shetty R, Ghosh A. Corneal cell therapy: with iPSCs, it is no more a far-sight. Stem Cell Res Ther. 2018;9(1):287. https:\/\/doi.org\/10.1186\/s13287-018-1036-5.","journal-title":"Stem Cell Res Ther"},{"key":"1286_CR174","doi-asserted-by":"publisher","first-page":"117959722412880","DOI":"10.1177\/11795972241288099","volume":"15","author":"S Zoghi","year":"2024","unstructured":"Zoghi S. Advancements in tissue engineering: a review of bioprinting techniques, scaffolds, and bioinks. Biomed Eng Comput Biol. 2024;15:11795972241288100. https:\/\/doi.org\/10.1177\/11795972241288099.","journal-title":"Biomed Eng Comput Biol"},{"key":"1286_CR175","doi-asserted-by":"crossref","unstructured":"Bharadwaj T, Thomas A, Verma D. Bioprinting. 2021. p. 45\u201396.","DOI":"10.1007\/978-981-33-6888-0_3"},{"key":"1286_CR176","doi-asserted-by":"publisher","DOI":"10.36922\/ijb.1669","author":"T Monostori","year":"2024","unstructured":"Monostori T, Sz\u0171cs D, Lov\u00e1szi B, Kem\u00e9ny L, Ver\u00e9b Z. Advances in tissue engineering and 3D bioprinting for corneal regeneration. IJB. 2024. https:\/\/doi.org\/10.36922\/ijb.1669.","journal-title":"IJB"},{"issue":"9","key":"1286_CR177","doi-asserted-by":"publisher","first-page":"871","DOI":"10.2217\/rme-2020-0202","volume":"16","author":"R Wongvisavavit","year":"2021","unstructured":"Wongvisavavit R, Parekh M, Ahmad S, Daniels JT. Challenges in corneal endothelial cell culture. Regen Med. 2021;16(9):871\u201391. https:\/\/doi.org\/10.2217\/rme-2020-0202.","journal-title":"Regen Med"},{"issue":"1","key":"1286_CR178","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-024-03672-w","volume":"15","author":"P Gr\u00f6nroos","year":"2024","unstructured":"Gr\u00f6nroos P, M\u00f6r\u00f6 A, Puistola P, Hopia K, Huuskonen M, Viheri\u00e4l\u00e4 T, et al. Bioprinting of human pluripotent stem cell-derived corneal endothelial cells with hydrazone crosslinked hyaluronic acid bioink. Stem Cell Res Ther. 2024;15(1):81. https:\/\/doi.org\/10.1186\/s13287-024-03672-w.","journal-title":"Stem Cell Res Ther"},{"key":"1286_CR179","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1193606","volume":"14","author":"X Wang","year":"2023","unstructured":"Wang X, Elbahrawi RT, Abdukadir AM, Ali ZM, Chan V, Corridon PR. A proposed model of xeno-keratoplasty using 3D printing and decellularization. Front Pharmacol. 2023;14:1193606. https:\/\/doi.org\/10.3389\/fphar.2023.1193606.","journal-title":"Front Pharmacol"},{"key":"1286_CR180","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.ijbiomac.2017.08.171","volume":"107","author":"W Aljohani","year":"2018","unstructured":"Aljohani W, Ullah MW, Zhang X, Yang G. Bioprinting and its applications in tissue engineering and regenerative medicine. Int J Biol Macromol. 2018;107:261\u201375. https:\/\/doi.org\/10.1016\/j.ijbiomac.2017.08.171.","journal-title":"Int J Biol Macromol"},{"key":"1286_CR181","doi-asserted-by":"publisher","DOI":"10.3390\/ijms252211884","author":"M Bertolin","year":"2024","unstructured":"Bertolin M, Ruzza A, Barbaro V, Zanetti E, Ponzin D, Ferrari S. Factors affecting the density of corneal endothelial cells cultured from donor corneas. Int J Mol Sci. 2024. https:\/\/doi.org\/10.3390\/ijms252211884.","journal-title":"Int J Mol Sci"},{"issue":"8","key":"1286_CR182","first-page":"1026","volume":"66","author":"L Rosenberg Belmaker","year":"2025","unstructured":"Rosenberg Belmaker L, Marcus M, Malki M, et al. Precise-Bio\u2019s PVEK implant for treatment of corneal endothelial dysfunction. Investig Ophthalmol Vis Sci. 2025;66(8):1026.","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"9","key":"1286_CR183","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1002\/jbm.a.36702","volume":"107","author":"DF Duarte Campos","year":"2019","unstructured":"Duarte Campos DF, Rohde M, Ross M, Anvari P, Blaeser A, Vogt M, et al. Corneal bioprinting utilizing collagen-based bioinks and primary human keratocytes. J Biomed Mater Res A. 2019;107(9):1945\u201353. https:\/\/doi.org\/10.1002\/jbm.a.36702.","journal-title":"J Biomed Mater Res A"},{"key":"1286_CR184","doi-asserted-by":"publisher","first-page":"1423864","DOI":"10.3389\/fbioe.2024.1423864","volume":"12","author":"ZJ Xie","year":"2024","unstructured":"Xie ZJ, Yuan BW, Chi MM, Hong J. Focus on seed cells: stem cells in 3D bioprinting of corneal grafts. Front Bioeng Biotechnol. 2024;12:1423864. https:\/\/doi.org\/10.3389\/fbioe.2024.1423864.","journal-title":"Front Bioeng Biotechnol"},{"key":"1286_CR185","doi-asserted-by":"publisher","DOI":"10.3390\/biomimetics9030145","author":"KY Wu","year":"2024","unstructured":"Wu KY, Tabari A, Mazerolle \u00c9, Tran SD. Towards precision ophthalmology: the role of 3D printing and bioprinting in oculoplastic surgery, retinal, corneal, and glaucoma treatment. Biomimetics. 2024. https:\/\/doi.org\/10.3390\/biomimetics9030145.","journal-title":"Biomimetics"},{"key":"1286_CR186","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1016\/j.omtn.2022.01.005","volume":"27","author":"Q Wang","year":"2022","unstructured":"Wang Q, Dou S, Zhang B, et al. Heterogeneity of human corneal endothelium implicates lncRNA NEAT1 in Fuchs endothelial corneal dystrophy. Mol Ther Nucleic Acids. 2022;27:880\u201393. https:\/\/doi.org\/10.1016\/j.omtn.2022.01.005.","journal-title":"Mol Ther Nucleic Acids"},{"issue":"12","key":"1286_CR187","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.1002\/stem.2915","volume":"36","author":"YK Chang","year":"2018","unstructured":"Chang YK, Hwang JS, Chung TY, Shin YJ. SOX2 activation using CRISPR\/dCas9 promotes wound healing in corneal endothelial cells. Stem Cells. 2018;36(12):1851\u201362. https:\/\/doi.org\/10.1002\/stem.2915.","journal-title":"Stem Cells"},{"issue":"33","key":"1286_CR188","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202203257","volume":"9","author":"E Maurizi","year":"2022","unstructured":"Maurizi E, Martella DA, Schiroli D, Merra A, Mustfa SA, Pellegrini G, et al. Nanoneedles induce targeted siRNA\u00a0silencing of p16 in the human corneal endothelium. Adv Sci. 2022;9(33):e2203257. https:\/\/doi.org\/10.1002\/advs.202203257.","journal-title":"Adv Sci"},{"key":"1286_CR189","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6644463","volume":"2021","author":"R Nuzzi","year":"2021","unstructured":"Nuzzi R, Buono L, Scalabrin S, De Iuliis M, Bussolati B. Effect of stem cell-derived extracellular vesicles on damaged human corneal endothelial cells. Stem Cells Int. 2021;2021:6644463. https:\/\/doi.org\/10.1155\/2021\/6644463.","journal-title":"Stem Cells Int"},{"issue":"8","key":"1286_CR190","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1080\/09537104.2022.2105829","volume":"33","author":"R Widyaningrum","year":"2022","unstructured":"Widyaningrum R, Wu YW, Delila L, Lee DY, Wang TJ, Burnouf T. In vitro evaluation of platelet extracellular vesicles (PEVs) for corneal endothelial regeneration. Platelets. 2022;33(8):1237\u201350. https:\/\/doi.org\/10.1080\/09537104.2022.2105829.","journal-title":"Platelets"}],"container-title":["Ophthalmology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-025-01286-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40123-025-01286-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40123-025-01286-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T08:33:04Z","timestamp":1770453184000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40123-025-01286-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,4]]},"references-count":190,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["1286"],"URL":"https:\/\/doi.org\/10.1007\/s40123-025-01286-w","relation":{},"ISSN":["2193-8245","2193-6528"],"issn-type":[{"value":"2193-8245","type":"print"},{"value":"2193-6528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,4]]},"assertion":[{"value":"5 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Giuseppe Giannaccare, Filippo Lixi, Carina Slidsborg, Gamze Ozkan, Alina G Gheorghe, Ana-Maria Arghirescu, Assem Namazbayeva, Mana Monfared, Rohan Bir Singh, Vishal Jhanji, Carlo Nucci and Giulia Coco have nothing to disclose. Patients were not involved in the design of the study or the dissemination of the results.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}