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Jun Jin has nothing to disclose. Runchuan Li has nothing to disclose. Chee Chew Yip has nothing to disclose. Kelvin Kam Lung Chong has nothing to disclose. Terry J. Smith was issued patents for targeting IGF-IR as therapy for autoimmune diseases, including TAO, held by Lundquist Institute\/UCLA and University of Michigan; and serves as consultant, Amgen (formerly Horizon), Viridian Therapeutics, Lundbeck, Argenx, Lassen Therapeutics, Minghui Pharmaceuticals, Innovent Biologics, Bristol Myers Squibb, Arrowhead Pharma, Ollin Bioscience, and Escient Pharma. Jing Sun has nothing to disclose. Huifang Zhou has nothing to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}