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Nguyen, and Isabella Tunon-Robinson, declare the following: Payment\/services info:\u00a0this study was sponsored by AbbVie. AbbVie funded this study and paid a subscription fee to Verana Health (San Francisco, CA) to have access to the IRIS\n                      \u00ae\n                      Registry. AbbVie employees, Runzhi Zhang and Ashley K. Nguyen, participated in the study design, research, analysis, data collection, interpretation of data, reviewing, and approval of the publication. Financial relationships:\u00a0Runzhi Zhang and Ashley K. Nguyen are employees at AbbVie and hold stock\/stock options from AbbVie. Isabella Tunon-Robinson declares that she is a paid intern at AbbVie. Other relationships:\u00a0all authors, Runzhi Zhang, Ashley K. Nguyen and Isabella Tunon-Robinson, have declared that there are no other relationships or activities that could appear to have influenced the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"In accordance with FDA exemption 45 CFR 46.104(d)(2)(i), the use of de-identified clinical data does not require patient consent, and institutional review board (IRB) or ethics committee approval is not required. The research adhered to the principles outlined in the Helsinki Declaration of 1964 and its later amendments. The manuscript was written following the principles and guidelines set by the Committee on Publication Ethics (COPE) in its research and publication practices. The research also complied with our institutional ethical standards of research reporting to uphold standards related to transparency, integrity, authorship, disclosure of conflicts of interest, and ethical conduct in publishing.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}