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Williams: grant support from the National Science Foundation, the Eye and Ear Foundation of Pittsburgh, and the Henry L. Hillman Foundation. Andrew M. Williams: consultant for Glaukos. Anne L. Coleman: the Department of Ophthalmology at University of California, Los Angeles (UCLA) is a recipient of an unrestricted grant from Research to Prevent Blindness. Dr. Anne L. Coleman and the Department of Ophthalmology are in receipt of the National institutes of Health (NIH) K12 Clinician-Scientist Eye Training (C-SET) Program award. Brian Stagg: NIH, K23EY032577, EY014800 (BCS); and unrestricted grant from Research to Prevent Blindness to the Moran Eye Center. Eric Newton: employee of Glaukos Corporation. 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