{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:22:39Z","timestamp":1791210159855,"version":"4.1.0"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100008257","name":"Tarbiat Modares University","doi-asserted-by":"publisher","award":["1"],"award-info":[{"award-number":["1"]}],"id":[{"id":"10.13039\/501100008257","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["DARU J Pharm Sci"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1007\/s40199-020-00331-2","type":"journal-article","created":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T17:02:22Z","timestamp":1586365342000},"page":"209-219","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["HSA-curcumin nanoparticles: a promising substitution for Curcumin as a Cancer chemoprevention and therapy"],"prefix":"10.1007","volume":"28","author":[{"given":"Zahra","family":"Matloubi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhair","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,4,8]]},"reference":[{"issue":"11","key":"331_CR1","first-page":"1994","volume":"19","author":"M Yallapu","year":"2013","unstructured":"Yallapu M, Jaggi MM, Chauhan SC. Curcumin nanomedicine: a road to cancer therapeutics. Curr Pharm Des. 2013;19(11):1994\u20132010.","journal-title":"Curr Pharm Des"},{"issue":"8","key":"331_CR2","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1158\/1940-6207.CAPR-10-0006","volume":"4","author":"SS Bansal","year":"2011","unstructured":"Bansal SS, et al. Advanced drug delivery systems of curcumin for cancer chemoprevention. Cancer Prev Res. 2011;4(8):1158\u201371.","journal-title":"Cancer Prev Res"},{"key":"331_CR3","volume-title":"10 Curcumin\u2014biological and medicinal properties","author":"BB Aggarwal","year":"2006","unstructured":"Aggarwal, B.B., et al., 10 Curcumin\u2014biological and medicinal properties. 2006."},{"issue":"3","key":"331_CR4","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2174\/187152006776930918","volume":"6","author":"S Singh","year":"2006","unstructured":"Singh S, Khar A. Biological effects of curcumin and its role in cancer chemoprevention and therapy. ANTI-CANCER AGENT ME. (Formerly Current Medicinal Chemistry-Anti-Cancer Agents). 2006;6(3):259\u201370.","journal-title":"ANTI-CANCER AGENT ME. (Formerly Current Medicinal Chemistry-Anti-Cancer Agents)"},{"issue":"1","key":"331_CR5","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1208\/s12248-012-9432-8","volume":"15","author":"SC Gupta","year":"2013","unstructured":"Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013;15(1):195\u2013218.","journal-title":"AAPS J"},{"issue":"13","key":"331_CR6","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/j.ejca.2005.05.009","volume":"41","author":"R Sharma","year":"2005","unstructured":"Sharma R, Gescher A, Steward W. Curcumin: the story so far. Eur J Cancer. 2005;41(13):1955\u201368.","journal-title":"Eur J Cancer"},{"issue":"6","key":"331_CR7","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.3892\/ol.2012.928","volume":"4","author":"J Zheng","year":"2012","unstructured":"Zheng J. Energy metabolism of cancer: glycolysis versus oxidative phosphorylation. Oncol Lett. 2012;4(6):1151\u20137.","journal-title":"Oncol Lett"},{"issue":"9","key":"331_CR8","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nrc3110","volume":"11","author":"BA Webb","year":"2011","unstructured":"Webb BA, Chimenti M, Jacobson MP, Barber DL. Dysregulated pH: a perfect storm for cancer progression. Nat Rev Cancer. 2011;11(9):671\u20137.","journal-title":"Nat Rev Cancer"},{"key":"331_CR9","doi-asserted-by":"crossref","unstructured":"Gerweck LE. Tumor pH: implications for treatment and novel drug design. Semin Radiat Oncol. 1998. Elsevier. .","DOI":"10.1016\/S1053-4296(98)80043-X"},{"issue":"6","key":"331_CR10","first-page":"1194","volume":"56","author":"LE Gerweck","year":"1996","unstructured":"Gerweck LE, Seetharaman K. Cellular pH gradient in tumor <em>versus<\/em> Normal tissue: potential exploitation for the treatment of Cancer. Cancer Res. 1996;56(6):1194\u20138.","journal-title":"Cancer Res"},{"issue":"12","key":"331_CR11","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1016\/S0731-7085(96)02024-9","volume":"15","author":"Y-J Wang","year":"1997","unstructured":"Wang Y-J, et al. Stability of curcumin in buffer solutions and characterization of its degradation products. J Pharm Biomed Anal. 1997;15(12):1867\u201376.","journal-title":"J Pharm Biomed Anal"},{"issue":"2","key":"331_CR12","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2147\/IJN.S596","volume":"3","author":"WH De Jong","year":"2008","unstructured":"De Jong WH, Borm PJ. Drug delivery and nanoparticles: applications and hazards. Int J Nanomedicine. 2008;3(2):133\u201349.","journal-title":"Int J Nanomedicine"},{"issue":"1","key":"331_CR13","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/s40089-014-0094-7","volume":"4","author":"AZ Mirza","year":"2014","unstructured":"Mirza AZ, Siddiqui FA. Nanomedicine and drug delivery: a mini review. Int Nano Lett. 2014;4(1):94.","journal-title":"Int Nano Lett"},{"key":"331_CR14","unstructured":"Syed Abdul Kuddusa, S.A.R.a.F.A., Cancer nanotechnology: hopes and hurdles. International Journal Of Environmental & Science Education (IJESE), 2017. 12: p. 1317\u20131340."},{"key":"331_CR15","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.3389\/fphar.2017.01002","volume":"8","author":"T Khan","year":"2018","unstructured":"Khan T, Gurav P. PhytoNanotechnology: enhancing delivery of plant based anti-cancer drugs. Front Pharmacol. 2018;8:1002.","journal-title":"Front Pharmacol"},{"key":"331_CR16","unstructured":"Kar SK, et al. Curcumin nanoparticles and methods of producing the same. 2009. Google Patents."},{"issue":"8","key":"331_CR17","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1517\/17425247.2014.916686","volume":"11","author":"W-H Lee","year":"2014","unstructured":"Lee W-H, Loo CY, Young PM, Traini D, Mason RS, Rohanizadeh R. Recent advances in curcumin nanoformulation for cancer therapy. Expert Opin Drug Deliv. 2014;11(8):1183\u2013201.","journal-title":"Expert Opin Drug Deliv"},{"issue":"10","key":"331_CR18","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1016\/j.biomaterials.2013.12.090","volume":"35","author":"O Naksuriya","year":"2014","unstructured":"Naksuriya O, Okonogi S, Schiffelers RM, Hennink WE. Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment. Biomaterials. 2014;35(10):3365\u201383.","journal-title":"Biomaterials"},{"issue":"6","key":"331_CR19","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1208\/s12248-015-9811-z","volume":"17","author":"MM Yallapu","year":"2015","unstructured":"Yallapu MM, Nagesh PK, Jaggi M, Chauhan SC. Therapeutic applications of curcumin nanoformulations. AAPS J. 2015;17(6):1341\u201356.","journal-title":"AAPS J"},{"issue":"3","key":"331_CR20","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1080\/01635581.2017.1285405","volume":"69","author":"PA Subramani","year":"2017","unstructured":"Subramani PA, Panati K, Narala VR. Curcumin nanotechnologies and its anticancer activity. Nutr Cancer. 2017;69(3):381\u201393.","journal-title":"Nutr Cancer"},{"key":"331_CR21","first-page":"51","volume":"2011","author":"S Wang","year":"2011","unstructured":"Wang S, et al. Nanotechnologies for curcumin: an ancient puzzler meets modern solutions. J Nanomater. 2011;2011:51.","journal-title":"J Nanomater"},{"issue":"8","key":"331_CR22","first-page":"32","volume":"9","author":"A Loxley","year":"2009","unstructured":"Loxley A. Solid lipid nanoparticles for the delivery of pharmaceutical actives. Drug Deliv Technol. 2009;9(8):32\u20137.","journal-title":"Drug Deliv Technol"},{"key":"331_CR23","first-page":"1281","volume":"27","author":"MH Rahman","year":"2014","unstructured":"Rahman MH, Ramanathan M, Sankar V. Preparation, characterization and in vitro cytotoxicity assay of curcumin loaded solid lipid nanoparticle in IMR32 neuroblastoma cell line. Pak J Pharm Sci. 2014;27:1281\u20135.","journal-title":"Pak J Pharm Sci"},{"issue":"6","key":"331_CR24","doi-asserted-by":"crossref","first-page":"537","DOI":"10.3109\/02652048.2011.590615","volume":"28","author":"D Chirio","year":"2011","unstructured":"Chirio D, et al. Formulation of curcumin-loaded solid lipid nanoparticles produced by fatty acids coacervation technique. J Microencapsul. 2011;28(6):537\u201348.","journal-title":"J Microencapsul"},{"issue":"5","key":"331_CR25","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.surg.2011.12.014","volume":"151","author":"WS Orr","year":"2012","unstructured":"Orr WS, Denbo JW, Saab KR, Myers AL, Ng CY, Zhou J, et al. RETRACTED: liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition. Surgery. 2012;151(5):736\u201344.","journal-title":"Surgery"},{"issue":"6","key":"331_CR26","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1002\/cncr.21300","volume":"104","author":"L Li","year":"2005","unstructured":"Li L, Braiteh FS, Kurzrock R. Liposome-encapsulated curcumin. Cancer. 2005;104(6):1322\u201331.","journal-title":"Cancer"},{"issue":"3","key":"331_CR27","first-page":"9","volume":"2","author":"MD Esmatabadi","year":"2015","unstructured":"Esmatabadi MD, et al. Comparative evaluation of curcumin and curcumin loaded-dendrosome nanoparticle effects on the viability of SW480 colon carcinoma and Huh7 hepatoma cells. Research Journal of Pharmacognosy (RJP). 2015;2(3):9\u201316.","journal-title":"Research Journal of Pharmacognosy (RJP)"},{"key":"331_CR28","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.7314\/APJCP.2015.16.6.2473","volume":"16","author":"MD Esmatabadi","year":"2015","unstructured":"Esmatabadi MD, et al. Dendrosomal curcumin inhibits metastatic potential of human SW480 colon cancer cells through down-regulation of claudin1, zeb1 and hef1-1 gene expression. Asian Pac J of Cancer Prev. 2015;16:2473\u201381.","journal-title":"Asian Pac J of Cancer Prev"},{"issue":"1","key":"331_CR29","first-page":"63","volume":"17","author":"V Erfani-Moghadam","year":"2014","unstructured":"Erfani-Moghadam V, et al. Design and synthesis of a novel Dendrosome and a PEGylated PAMAM Dendrimer Nanocarrier to improve the anticancer effect of turmeric (Curcuma longa) Curcumin. Modares Journal of Medical Sciences: Pathobiology. 2014;17(1):63\u201377.","journal-title":"Modares Journal of Medical Sciences: Pathobiology"},{"issue":"5","key":"331_CR30","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1021\/mp4000019","volume":"10","author":"P Zou","year":"2013","unstructured":"Zou P, Helson L, Maitra A, Stern ST, McNeil S. Polymeric curcumin nanoparticle pharmacokinetics and metabolism in bile duct cannulated rats. Mol Pharm. 2013;10(5):1977\u201387.","journal-title":"Mol Pharm"},{"key":"331_CR31","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.cej.2013.01.069","volume":"221","author":"H Souguir","year":"2013","unstructured":"Souguir H, et al. Nanoencapsulation of curcumin in polyurethane and polyurea shells by an emulsion diffusion method. Chem Eng J. 2013;221:133\u201345.","journal-title":"Chem Eng J"},{"issue":"3","key":"331_CR32","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1002\/jbm.a.33203","volume":"99","author":"S Nagarajan","year":"2011","unstructured":"Nagarajan S, Reddy BSR, Tsibouklis J. In vitro effect on cancer cells: synthesis and preparation of polyurethane membranes for controlled delivery of curcumin. J J Biomed Mater Res A. 2011;99(3):410\u20137.","journal-title":"J J Biomed Mater Res A"},{"issue":"5","key":"331_CR33","doi-asserted-by":"crossref","first-page":"464","DOI":"10.4161\/cbt.11.5.14410","volume":"11","author":"KJ Lim","year":"2011","unstructured":"Lim KJ, Bisht S, Bar EE, Maitra A, Eberhart CG. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol Ther. 2011;11(5):464\u201373.","journal-title":"Cancer Biol Ther"},{"key":"331_CR34","first-page":"5355","volume":"10","author":"D Betbeder","year":"2015","unstructured":"Betbeder D, et al. Evolution of availability of curcumin inside poly-lactic-co-glycolic acid nanoparticles: impact on antioxidant and antinitrosant properties. Int J Nanomedicine. 2015;10:5355.","journal-title":"Int J Nanomedicine"},{"issue":"1","key":"331_CR35","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.drudis.2011.09.009","volume":"17","author":"MM Yallapu","year":"2012","unstructured":"Yallapu MM, Jaggi M, Chauhan SC. Curcumin nanoformulations: a future nanomedicine for cancer. Drug Discov Today. 2012;17(1):71\u201380.","journal-title":"Drug Discov Today"},{"issue":"1","key":"331_CR36","first-page":"001","volume":"6","author":"AK Dutta","year":"2013","unstructured":"Dutta AK, Ikiki E. Novel drug delivery systems to improve bioavailability of curcumin. J Bioequiv Availab. 2013;6(1):001\u20139.","journal-title":"J Bioequiv Availab"},{"issue":"6","key":"331_CR37","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2217\/nnm.10.67","volume":"5","author":"H Tang","year":"2010","unstructured":"Tang H, Murphy CJ, Zhang B, Shen Y, Sui M, van Kirk E, et al. Amphiphilic curcumin conjugate-forming nanoparticles as anticancer prodrug and drug carriers: in vitro and in vivo effects. Nanomedicine. 2010;5(6):855\u201365.","journal-title":"Nanomedicine"},{"issue":"6","key":"331_CR38","doi-asserted-by":"crossref","first-page":"747","DOI":"10.2217\/nnm.14.21","volume":"9","author":"J-R Peng","year":"2014","unstructured":"Peng J-R, Qian Z-Y. Drug delivery systems for overcoming the bioavailability of curcumin: not only the nanoparticle matters. Nanomedicine. 2014;9(6):747\u201350.","journal-title":"Nanomedicine"},{"issue":"1","key":"331_CR39","doi-asserted-by":"crossref","first-page":"253","DOI":"10.2214\/ajr.181.1.1810253","volume":"181","author":"B Damascelli","year":"2003","unstructured":"Damascelli B, Patelli GL, Lanocita R, di Tolla G, Frigerio LF, Marchian\u00f2 A, et al. A novel intraarterial chemotherapy using paclitaxel in albumin nanoparticles to treat advanced squamous cell carcinoma of the tongue: preliminary findings. AJR Am J Roentgenol. 2003;181(1):253\u201360.","journal-title":"AJR Am J Roentgenol"},{"key":"331_CR40","volume-title":"Molecular umbrellas and human serum albumin as novel drug delivery vehicles","author":"HK Kouyoumdjian","year":"2009","unstructured":"Kouyoumdjian, H.K., Molecular umbrellas and human serum albumin as novel drug delivery vehicles. 2009."},{"issue":"2","key":"331_CR41","first-page":"542","volume":"4","author":"SK Kushwaha","year":"2012","unstructured":"Kushwaha SK, et al. Novel drug delivery system for anticancer drug: a review. Int J PharmTech Res. 2012;4(2):542\u201353.","journal-title":"Int J PharmTech Res"},{"key":"331_CR42","volume-title":"Anti-cancer nanoparticulate drug delivery system using biodegradable polymers","author":"H Gopinath","year":"2013","unstructured":"Gopinath, H., et al., Anti-cancer nanoparticulate drug delivery system using biodegradable polymers. 2013."},{"issue":"1","key":"331_CR43","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3109\/1061186X.2012.729214","volume":"21","author":"LP Kolluru","year":"2013","unstructured":"Kolluru LP, Rizvi SA, D'Souza M, D'Souza MJ. Formulation development of albumin based theragnostic nanoparticles as a potential delivery system for tumor targeting. J Drug Target. 2013;21(1):77\u201386.","journal-title":"J Drug Target"},{"key":"331_CR44","doi-asserted-by":"crossref","unstructured":"Lohcharoenkal W, et al. Protein nanoparticles as drug delivery carriers for cancer therapy. Biomed Res Int. 2014;2014.","DOI":"10.1155\/2014\/180549"},{"issue":"1","key":"331_CR45","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40591-016-0048-8","volume":"4","author":"MT Larsen","year":"2016","unstructured":"Larsen MT, et al. Albumin-based drug delivery: harnessing nature to cure disease. Molecular and cellular therapies. 2016;4(1):3.","journal-title":"Molecular and cellular therapies"},{"issue":"3","key":"331_CR46","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S0022-2275(20)39014-3","volume":"2","author":"A Saifer","year":"1961","unstructured":"Saifer A, Goldman L. The free fatty acids bound to human serum albumin. J Lipid Res. 1961;2(3):268\u201370.","journal-title":"J Lipid Res"},{"key":"331_CR47","doi-asserted-by":"crossref","unstructured":"Van der Vusse, G.J., et al., Transport of long-chain fatty acids across the muscular endothelium, in Skeletal muscle metabolism in exercise and diabetes. 1998, Springer. p. 181\u2013191.","DOI":"10.1007\/978-1-4899-1928-1_17"},{"issue":"2","key":"331_CR48","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4103\/2230-973X.82432","volume":"1","author":"A Jithan","year":"2011","unstructured":"Jithan A, et al. Preparation and characterization of albumin nanoparticles encapsulating curcumin intended for the treatment of breast cancer. Int J Pharm Investig. 2011;1(2):119.","journal-title":"Int J Pharm Investig"},{"issue":"1","key":"331_CR49","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.ijpharm.2010.10.041","volume":"403","author":"TH Kim","year":"2011","unstructured":"Kim TH, et al. Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity. I Int J Pharm. 2011;403(1):285\u201391.","journal-title":"I Int J Pharm"},{"issue":"1","key":"331_CR50","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1475-2891-9-69","volume":"9","author":"D Gupta","year":"2010","unstructured":"Gupta D, Lis CG. Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the epidemiological literature. Nutr J. 2010;9(1):69.","journal-title":"Nutr J"},{"issue":"2","key":"331_CR51","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/carcin\/bgu247","volume":"36","author":"X Liu","year":"2014","unstructured":"Liu X, Meng QH, Ye Y, Hildebrandt MA, Gu J, Wu X. Prognostic significance of pretreatment serum levels of albumin, LDH and total bilirubin in patients with non-metastatic breast cancer. Carcinogenesis. 2014;36(2):243\u20138.","journal-title":"Carcinogenesis"},{"issue":"2","key":"331_CR52","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1634\/theoncologist.2015-0284","volume":"21","author":"O K\u00f6nigsbr\u00fcgge","year":"2016","unstructured":"K\u00f6nigsbr\u00fcgge O, Posch F, Riedl J, Reitter EM, Zielinski C, Pabinger I, et al. Association between decreased serum albumin with risk of venous thromboembolism and mortality in cancer patients. Oncologist. 2016;21(2):252\u20137.","journal-title":"Oncologist"},{"issue":"5","key":"331_CR53","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1093\/fampra\/cmw051","volume":"33","author":"SW Merriel","year":"2016","unstructured":"Merriel SW, Carroll R, Hamilton F, Hamilton W. Association between unexplained hypoalbuminaemia and new cancer diagnoses in UK primary care patients. Fam Pract. 2016;33(5):449\u201352.","journal-title":"Fam Pract"},{"issue":"9\u201310","key":"331_CR54","first-page":"945","volume":"59","author":"ME Sitar","year":"2013","unstructured":"Sitar ME, Aydin S, Cakatay U. Human serum albumin and its relation with oxidative stress. Clin Lab. 2013;59(9\u201310):945\u201352.","journal-title":"Clin Lab"},{"issue":"1","key":"331_CR55","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2110-5820-3-4","volume":"3","author":"M Taverna","year":"2013","unstructured":"Taverna M, et al. Specific antioxidant properties of human serum albumin. Ann Intensive Care. 2013;3(1):4.","journal-title":"Ann Intensive Care"},{"issue":"2","key":"331_CR56","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0378-5173(99)00420-2","volume":"196","author":"C Weber","year":"2000","unstructured":"Weber C, Kreuter J, Langer K. Desolvation process and surface characteristics of HSA-nanoparticles. Int J Pharm. 2000;196(2):197\u2013200.","journal-title":"Int J Pharm"},{"issue":"1","key":"331_CR57","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0378-5173(99)00370-1","volume":"194","author":"C Weber","year":"2000","unstructured":"Weber C, Coester C, Kreuter J, Langer K. Desolvation process and surface characterisation of protein nanoparticles. Int J Pharm. 2000;194(1):91\u2013102.","journal-title":"Int J Pharm"},{"issue":"2","key":"331_CR58","first-page":"255","volume":"12","author":"S Honary","year":"2013","unstructured":"Honary S, Zahir F. Effect of zeta potential on the properties of nano-drug delivery systems-a review (part 1). Trop J Pharm Res. 2013;12(2):255\u201364.","journal-title":"Trop J Pharm Res"},{"issue":"31","key":"331_CR59","doi-asserted-by":"crossref","first-page":"4600","DOI":"10.1016\/j.biomaterials.2007.07.029","volume":"28","author":"S Patil","year":"2007","unstructured":"Patil S, et al. Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. Biomaterials. 2007;28(31):4600\u20137.","journal-title":"Biomaterials"},{"issue":"5","key":"331_CR60","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.cell.2008.08.021","volume":"134","author":"PP Hsu","year":"2008","unstructured":"Hsu PP, Sabatini DM. Cancer cell metabolism: Warburg and beyond. Cell. 2008;134(5):703\u20137.","journal-title":"Cell"},{"issue":"6","key":"331_CR61","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.ccr.2008.05.005","volume":"13","author":"G Kroemer","year":"2008","unstructured":"Kroemer G, Pouyssegur J. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell. 2008;13(6):472\u201382.","journal-title":"Cancer Cell"},{"issue":"2","key":"331_CR62","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s00232-012-9516-5","volume":"246","author":"I Dobrzy\u0144ska","year":"2013","unstructured":"Dobrzy\u0144ska I, Skrzydlewska E, Figaszewski ZA. Changes in electric properties of human breast cancer cells. J Membr Biol. 2013;246(2):161\u20136.","journal-title":"J Membr Biol"},{"issue":"1","key":"331_CR63","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1758-5996-3-11","volume":"3","author":"E Frei","year":"2011","unstructured":"Frei E. Albumin binding ligands and albumin conjugate uptake by cancer cells. Diabetol Metab Syndr. 2011;3(1):11.","journal-title":"Diabetol Metab Syndr"},{"key":"331_CR64","first-page":"5435","volume":"10","author":"L Mocan","year":"2015","unstructured":"Mocan L, et al. Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus\u2013ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor. Int J Nanomedicine. 2015;10:5435.","journal-title":"Int J Nanomedicine"},{"key":"331_CR65","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3389\/fphys.2014.00299","volume":"5","author":"AM Merlot","year":"2014","unstructured":"Merlot AM, Kalinowski DS, Richardson DR. Unraveling the mysteries of serum albumin\u2014more than just a serum protein. Front Physiol. 2014;5:299.","journal-title":"Front Physiol"},{"issue":"42","key":"331_CR66","doi-asserted-by":"crossref","first-page":"24995","DOI":"10.1074\/jbc.270.42.24995","volume":"270","author":"S Singh","year":"1995","unstructured":"Singh S, Aggarwal BB. Activation of transcription factor NF-\u03baB is suppressed by curcumin (diferuloylmethane). J Biol Chem. 1995;270(42):24995\u20135000.","journal-title":"J Biol Chem"},{"key":"331_CR67","unstructured":"Buhrmann, C., et al., Curcumin modulates NF-\u03baB-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase-Akt pathway. J. Biol Chem, 2011: p. jbc. M111. 256180."},{"issue":"2","key":"331_CR68","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.intimp.2011.12.009","volume":"12","author":"A Olivera","year":"2012","unstructured":"Olivera A, et al. Inhibition of the NF-\u03baB signaling pathway by the curcumin analog, 3, 5-Bis (2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties. Int Immunopharmacol. 2012;12(2):368\u201377.","journal-title":"Int Immunopharmacol"},{"issue":"3","key":"331_CR69","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.jhep.2015.04.018","volume":"63","author":"JU Marquardt","year":"2015","unstructured":"Marquardt JU, Gomez-Quiroz L, Arreguin Camacho LO, Pinna F, Lee YH, Kitade M, et al. Curcumin effectively inhibits oncogenic NF-\u03baB signaling and restrains stemness features in liver cancer. J Hepatol. 2015;63(3):661\u20139.","journal-title":"J Hepatol"},{"issue":"4","key":"331_CR70","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1007\/s12032-009-9344-3","volume":"27","author":"J Yang","year":"2010","unstructured":"Yang J, Cao Y, Sun J, Zhang Y. Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells. Med Oncol. 2010;27(4):1114\u20138.","journal-title":"Med Oncol"},{"key":"331_CR71","volume-title":"Curcumin prevents tumor-induced T cell apoptosis through stat-5a-mediated Bcl-2 induction","author":"S Bhattacharyya","year":"2007","unstructured":"Bhattacharyya, S., et al., Curcumin prevents tumor-induced T cell apoptosis through stat-5a-mediated Bcl-2 induction. J. Biol Chem, 2007."},{"issue":"9","key":"331_CR72","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1158\/1535-7163.1101.3.9","volume":"3","author":"C Syng-ai","year":"2004","unstructured":"Syng-ai C, Kumari AL, Khar A. Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. Mol Cancer Ther. 2004;3(9):1101\u20138.","journal-title":"Mol Cancer Ther"}],"container-title":["DARU Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40199-020-00331-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s40199-020-00331-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40199-020-00331-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T22:24:34Z","timestamp":1666304674000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s40199-020-00331-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,8]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["331"],"URL":"https:\/\/doi.org\/10.1007\/s40199-020-00331-2","relation":{},"ISSN":["2008-2231"],"issn-type":[{"value":"2008-2231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,8]]},"assertion":[{"value":"11 April 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that there are no conflicts of interest regarding the publication of this paper.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}