{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:12:31Z","timestamp":1788966751321,"version":"build-2803163510"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T00:00:00Z","timestamp":1593993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T00:00:00Z","timestamp":1593993600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["DARU J Pharm Sci"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Herpes zoster is an acute, painful, herpes skin disease caused by varicella-zoster virus, which may cause viral meningitis. Pregabalin has been shown to be efficacious in the treatment of pain in patients with herpes zoster. However, it has the side effects of neurotoxicity. We describe a 68-year-old female patient with herpes zoster, and she was treated with pregabalin. The patient presented with stuttering and frequent blepharospasm after 3\u00a0days of pregabalin treatment. Pregabalin was discontinued, the symptoms of stuttering and frequent blepharospasm completely resolved without any special treatment after one week. In this case, the etiology of stuttering and frequent blepharospasm may be related to pregabalin. Clinicians should be alert to the rare symptoms associated with the use of pregabalin.<\/jats:p>","DOI":"10.1007\/s40199-020-00354-9","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T17:04:03Z","timestamp":1594055043000},"page":"815-818","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Pregabalin-associated stuttering and frequent blepharospasm: case report and review."],"prefix":"10.1007","volume":"28","author":[{"given":"Lingzhi","family":"Ge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ni","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,6]]},"reference":[{"key":"354_CR1","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/1741-7015-8-58","volume":"8","author":"G Parruti","year":"2010","unstructured":"Parruti G, Tontodonati M, Rebuzzi C, Polilli E, Sozio F, Consorte A, et al. Predictors of pain intensity and persistence in a prospective Italian cohort of patients with herpes zoster: relevance of smoking, trauma and antiviral therapy. BMC Med. 2010;8:58.","journal-title":"BMC Med"},{"key":"354_CR2","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.2147\/JPR.S157856","volume":"11","author":"B Parsons","year":"2018","unstructured":"Parsons B, Pan X, Xie L, Chen Y, Ortiz M, Whalen E. Comparison of the efficacy and safety of pregabalin for postherpetic neuralgia in Chinese and international patients. J Pain Res. 2018;11:1699\u2013708.","journal-title":"J Pain Res"},{"issue":"6","key":"354_CR3","doi-asserted-by":"publisher","first-page":"e164","DOI":"10.1155\/2014\/280549","volume":"19","author":"Y Kanbayashi","year":"2014","unstructured":"Kanbayashi Y, Onishi K, Hosokawa T. Factors predicting adverse events associated with pregabalin administered for neuropathic pain relief. 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A copy of the written consent is available for review by the Editor of this journal. This study was approved by the First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital (QY201802016).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"This study was approved by the First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital (QY201802016), and written informed consent has been provided by the patient to have the case details published. Conflict of interest the authors do not report any Conflict of Interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"ICMJE form for disclosure of potential conflicts of interest"}}]}}