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Inclusion criteria were: age\u2009\u2265\u200918 years and anxiety symptoms. The clinical outcome was assessed using the GAD-7 scale, comparing scores between baseline (t0) and the final follow-up (t3). The humanistic outcome was assessed using the TSQM, applied 15 days after treatment initiation and again at t3. The economic outcome consisted of analyzing direct treatment-related costs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:italic>P. alata<\/jats:italic>\n                      demonstrated clinical effectiveness in 29 participants (96.7%). TSQM results indicated a perceived improvement in health status within the first weeks. Regarding economic outcomes, differences were observed between the protocols that included\n                      <jats:italic>P. alata<\/jats:italic>\n                      and the conventional treatments offered by the Brazilian Unified Health System.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      It was concluded that the use of\n                      <jats:italic>P. alata<\/jats:italic>\n                      extract for anxiety management is a potential therapeutic alternative for incorporation into the Brazilian Unified Health System.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40199-026-00591-4","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T04:04:13Z","timestamp":1770177853000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical, humanistic, and economic outcomes of Passiflora alata Curtis use in participants with mild to moderate anxiety: a non-randomized experimental study"],"prefix":"10.1007","volume":"34","author":[{"given":"Thatiane B\u00e1rbara de","family":"Barros","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Wiens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago Marques dos","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"issue":"2","key":"591_CR1","first-page":"65","volume":"32","author":"FT Santos","year":"2024","unstructured":"Santos FT. 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