{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T20:58:24Z","timestamp":1785445104274,"version":"3.56.0"},"reference-count":100,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Goa State Research Foundation (GSRF) under the GSRF Major Research Grant Scheme","award":["GSRF\/Schemes\/MajorGR\/13(i)\/2024\u201325\/866(vii)"],"award-info":[{"award-number":["GSRF\/Schemes\/MajorGR\/13(i)\/2024\u201325\/866(vii)"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["DARU J Pharm Sci"],"DOI":"10.1007\/s40199-026-00630-0","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:04:34Z","timestamp":1785384274000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three-dimensional printing as a transformative platform for patient-centric pediatric drug delivery: technologies, formulation strategies and clinical translation"],"prefix":"10.1007","volume":"34","author":[{"given":"Padmadip","family":"Phadte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mythili Krishna","family":"Jeedigunta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopalkrishna","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bothiraja","family":"Chellampillai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"630_CR1","doi-asserted-by":"publisher","first-page":"114507","DOI":"10.1016\/j.addr.2022.114507","volume":"190","author":"S Salunke","year":"2022","unstructured":"Salunke S, O\u2019Brien F, Tan DC, Harris D, Math MC, Ari\u00ebn T, Klein S, Timpe C. Oral drug delivery strategies for development of poorly water soluble drugs in paediatric patient population. Adv Drug Deliv Rev. 2022;190:114507. https:\/\/doi.org\/10.1016\/j.addr.2022.114507.","journal-title":"Adv Drug Deliv Rev"},{"key":"630_CR2","doi-asserted-by":"publisher","first-page":"100546","DOI":"10.1016\/j.rcsop.2024.100546","volume":"17","author":"A Elgammal","year":"2025","unstructured":"Elgammal A, Ryan J, Bradley C, Crean A, Bermingham M. Challenges prescribing and dispensing oral antibiotics with poor palatability for paediatric patients: A qualitative interview study with GPs and pharmacists. Exploratory Res Clin Social Pharm. 2025;17:100546. https:\/\/doi.org\/10.1016\/j.rcsop.2024.100546.","journal-title":"Exploratory Res Clin Social Pharm"},{"issue":"4","key":"630_CR3","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1111\/bcp.14705","volume":"88","author":"NP Giangreco","year":"2022","unstructured":"Giangreco NP, Elias JE, Tatonetti NP. No population left behind: Improving paediatric drug safety using informatics and systems biology. Br J Clin Pharmacol. 2022;88(4):1464\u201370. https:\/\/doi.org\/10.1111\/bcp.14705.","journal-title":"Br J Clin Pharmacol"},{"issue":"8","key":"630_CR4","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1016\/j.clinthera.2013.06.007","volume":"35","author":"JA Mennella","year":"2013","unstructured":"Mennella JA, Spector AC, Reed DR, Coldwell SE. The bad taste of medicines: overview of basic research on bitter taste. Clin Ther. 2013;35(8):1225\u201346. https:\/\/doi.org\/10.1016\/j.clinthera.2013.06.007.","journal-title":"Clin Ther"},{"issue":"3","key":"630_CR5","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1136\/archdischild-2011-300909","volume":"97","author":"D Baguley","year":"2012","unstructured":"Baguley D, Lim E, Bevan A, Pallet A, Faust SN. Prescribing for children\u2013taste and palatability affect adherence to antibiotics: a review. Arch Dis Child. 2012;97(3):293\u20137. https:\/\/doi.org\/10.1136\/archdischild-2011-300909.","journal-title":"Arch Dis Child"},{"issue":"2","key":"630_CR6","doi-asserted-by":"publisher","first-page":"e0282164","DOI":"10.1371\/journal.pone.0282164","volume":"18","author":"P Thevin","year":"2023","unstructured":"Thevin P, Curti C, Benech A, Jean C, Lamy E, Castera Ducros C, Primas N, Bertault-Peres P, Vanelle P. Low-dose erythromycin in pediatrics: Formulation and stability of 20\u00a0mg hard gelatin capsules. PLoS ONE. 2023;18(2):e0282164. https:\/\/doi.org\/10.1371\/journal.pone.0282164.","journal-title":"PLoS ONE"},{"issue":"1","key":"630_CR7","doi-asserted-by":"publisher","first-page":"44","DOI":"10.3390\/pharmaceutics12010044","volume":"12","author":"E Menditto","year":"2020","unstructured":"Menditto E, Orlando V, De Rosa G, Minghetti P, Musazzi UM, Cahir C, Kurczewska-Michalak M, Kardas P, Costa E, Sousa Lobo JM, Almeida IF. Patient centric pharmaceutical drug product design\u2014The impact on medication adherence. Pharmaceutics. 2020;12(1):44. https:\/\/doi.org\/10.3390\/pharmaceutics12010044.","journal-title":"Pharmaceutics"},{"issue":"9","key":"630_CR8","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.3390\/pharmaceutics16091212","volume":"16","author":"M Ahmed","year":"2024","unstructured":"Ahmed M, Tomlin S, Tuleu C, Garfield S. Real-World Evidence of 3D Printing of Personalised Paediatric Medicines and Evaluating Its Potential in Children with Cancer: A Scoping Review. Pharmaceutics. 2024;16(9):1212. https:\/\/doi.org\/10.3390\/pharmaceutics16091212.","journal-title":"Pharmaceutics"},{"issue":"11","key":"630_CR9","doi-asserted-by":"publisher","first-page":"1364","DOI":"10.3390\/pharmaceutics17111364","volume":"17","author":"N Cou\u021bi","year":"2025","unstructured":"Cou\u021bi N, Iurian S, Porfire A, Casian T, Iovanov R, Tomu\u021b\u0103 I. Three-Dimensional Printing in Paediatrics: Innovative Technology for Manufacturing Patient-Centred Drug Delivery Systems. Pharmaceutics. 2025;17(11):1364. https:\/\/doi.org\/10.3390\/pharmaceutics17111364.","journal-title":"Pharmaceutics"},{"key":"630_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s13346-026-02059-z","volume":"5","author":"CI Gioumouxouzis","year":"2026","unstructured":"Gioumouxouzis CI, Eleftheriadis GK, Kyriakidis AS, Karavasili C. Translation of pharmaceutical 3D printing to clinical point-of-care and industrial manufacturing. Drug Delivery and Translational Research. Feb. 2026;5:1\u20134. https:\/\/doi.org\/10.1007\/s13346-026-02059-z.","journal-title":"Feb"},{"key":"630_CR11","doi-asserted-by":"publisher","DOI":"10.33611\/trs.2025-005","author":"T Kagita","year":"2025","unstructured":"Kagita T, Gude S, Abburi SK, Devarakonda A, Maddineni S. Advancing 3D printing for personalized pediatric medicines: quality, safety, and good manufacturing practice compliance. Translational and Regulatory Sciences. 2025. https:\/\/doi.org\/10.33611\/trs.2025-005.","journal-title":"Translational and Regulatory Sciences"},{"key":"630_CR12","first-page":"274","volume":"66","author":"M Van Den Driessche","year":"2003","unstructured":"Van Den Driessche M, Veereman-Wauters G. Gastric emptying in infants and children. Acta Gastroenterol Belg. 2003;66:274\u201382.","journal-title":"Acta Gastroenterol Belg"},{"issue":"9","key":"630_CR13","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1007\/s00044-024-03360-7","volume":"64","author":"M Codaccioni","year":"2024","unstructured":"Codaccioni M, Southall RL, Dinh J, Johnson TN. Prediction of pediatric pharmacokinetics for CYP3A4 metabolized drugs: comparison of the performance of two hepatic ontogeny within a physiologically based pharmacokinetic model. J Clin Pharmacol. 2024;64(9):1083\u201394. https:\/\/doi.org\/10.1007\/s00044-024-03360-7.","journal-title":"J Clin Pharmacol"},{"issue":"12","key":"630_CR14","doi-asserted-by":"publisher","first-page":"2221","DOI":"10.1007\/s00044-024-03360-7","volume":"33","author":"M Vander Schaaf","year":"2024","unstructured":"Vander Schaaf M, Luth K, Townsend DM, Chessman KH, Mills CM, Garner SS, Peterson YK. CYP3A4 drug metabolism considerations in pediatric pharmacotherapy. Med Chem Res. 2024;33(12):2221\u201335. https:\/\/doi.org\/10.1007\/s00044-024-03360-7.","journal-title":"Med Chem Res"},{"key":"630_CR15","doi-asserted-by":"publisher","first-page":"145","DOI":"10.33263\/BRIAC146.145","volume":"14","author":"M Chandramouli","year":"2024","unstructured":"Chandramouli M, Basavanna V, Ningaiah S. A Comprehensive Review of Paediatric Drug Development: An Extensive Analysis of Present Difficulties and Prospects for the Future. Biointerface Res Appl Chem. 2024;14:145.","journal-title":"Biointerface Res Appl Chem"},{"issue":"4","key":"630_CR16","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1016\/j.xphs.2017.11.019","volume":"107","author":"T Ehtezazi","year":"2018","unstructured":"Ehtezazi T, Algellay M, Islam Y, Roberts M, Dempster NM, Sarker SD. The application of 3D printing in the formulation of multilayered fast dissolving oral films. J Pharm Sci. 2018;107(4):1076\u201385. https:\/\/doi.org\/10.1016\/j.xphs.2017.11.019.","journal-title":"J Pharm Sci"},{"key":"630_CR17","doi-asserted-by":"publisher","unstructured":"Chikkale AR, Nema RK. Challenges in pediatric formulations development: A. https:\/\/doi.org\/10.20959\/wjpr202010-18481","DOI":"10.20959\/wjpr202010-18481"},{"key":"630_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.120417","volume":"599","author":"M Fanous","year":"2021","unstructured":"Fanous M, Bitar M, Gold S, Sobczuk A, Hirsch S, Ogorka J, et al. Development of immediate release 3D-printed dosage forms for a poorly water-soluble drug by fused deposition modeling: study of morphology, solid state and dissolution. Int J Pharm. 2021;599:120417. https:\/\/doi.org\/10.1016\/j.ijpharm.2021.120417.","journal-title":"Int J Pharm"},{"key":"630_CR19","doi-asserted-by":"publisher","first-page":"119200","DOI":"10.1016\/j.ijpharm.2020.119200","volume":"580","author":"O Jennotte","year":"2020","unstructured":"Jennotte O, Koch N, Lechanteur A, Evrard B. Three-dimensional printing technology as a promising tool in bioavailability enhancement of poorly water-soluble molecules: a review. Int J Pharm. 2020;580:119200. https:\/\/doi.org\/10.1016\/j.ijpharm.2020.119200.","journal-title":"Int J Pharm"},{"key":"630_CR20","doi-asserted-by":"publisher","first-page":"100153","DOI":"10.1016\/j.ijpx.2022.100153","volume":"5","author":"J Dos Santos","year":"2023","unstructured":"Dos Santos J, de Souza Balbinot G, Buchner S, Collares FM, Windbergs M, Deon M, Beck RC. 3D printed matrix solid forms: Can the drug solubility and dose customisation affect their controlled release behaviour? Int J Pharmaceutics: X. 2023;5:100153. https:\/\/doi.org\/10.1016\/j.ijpx.2022.100153.","journal-title":"Int J Pharmaceutics: X"},{"issue":"7","key":"630_CR21","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1080\/17512433.2023.2233416","volume":"16","author":"AP McCloskey","year":"2023","unstructured":"McCloskey AP, Bracken L, Vasey N, Ehtezazi T. 3D printing\u2013an alternative strategy for pediatric medicines. Expert Rev Clin Pharmacol. 2023;16(7):613\u20136. https:\/\/doi.org\/10.1080\/17512433.2023.2233416.","journal-title":"Expert Rev Clin Pharmacol"},{"issue":"1","key":"630_CR22","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.ijpharm.2017.12.002","volume":"536","author":"G Verstraete","year":"2018","unstructured":"Verstraete G, Samaro A, Grymonpr\u00e9 W, Vanhoorne V, Van Snick B, Boone MN, Hellemans T, Van Hoorebeke L, Remon JP, Vervaet C. 3D printing of high drug loaded dosage forms using thermoplastic polyurethanes. Int J Pharm. 2018;536(1):318\u201325. https:\/\/doi.org\/10.1016\/j.ijpharm.2017.12.002.","journal-title":"Int J Pharm"},{"issue":"2","key":"630_CR23","doi-asserted-by":"publisher","first-page":"124","DOI":"10.3390\/pharmaceutics12020124","volume":"12","author":"MA Azad","year":"2020","unstructured":"Azad MA, Olawuni D, Kimbell G, Badruddoza AZ, Hossain MS, Sultana T. Polymers for extrusion-based 3D printing of pharmaceuticals: A holistic materials\u2013process perspective. Pharmaceutics. 2020;12(2):124. https:\/\/doi.org\/10.3390\/pharmaceutics12020124.","journal-title":"Pharmaceutics"},{"issue":"2","key":"630_CR24","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1208\/s12249-024-02749-2","volume":"25","author":"H Patil","year":"2024","unstructured":"Patil H, Vemula SK, Narala S, Lakkala P, Munnangi SR, Narala N, Jara MO, Williams RO III, Terefe H, Repka MA. Hot-melt extrusion: from theory to application in pharmaceutical formulation\u2014where are we now? AAPS PharmSciTech. 2024;25(2):37. https:\/\/doi.org\/10.1208\/s12249-024-02749-2.","journal-title":"AAPS PharmSciTech"},{"key":"630_CR25","doi-asserted-by":"publisher","unstructured":"Henry S, Vanhoorne V, Vervaet C. Fused deposition modeling (FDM) of pharmaceuticals. In: Additive Manufacturing in Pharmaceuticals. Singapore: Springer Nature Singapore; 2023. p. 45\u201396. https:\/\/doi.org\/10.1007\/978-981-99-2404-2_2.","DOI":"10.1007\/978-981-99-2404-2_2"},{"issue":"1\u20132","key":"630_CR26","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.ijpharm.2016.05.036","volume":"509","author":"A Melocchi","year":"2016","unstructured":"Melocchi A, Parietti F, Maroni A, Foppoli A, Gazzaniga A, Zema L. Hot-melt extruded filaments based on pharmaceutical grade polymers for 3D printing by fused deposition modeling. Int J Pharm. 2016;509(1\u20132):255\u201363. https:\/\/doi.org\/10.1016\/j.ijpharm.2016.05.036.","journal-title":"Int J Pharm"},{"key":"630_CR27","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.jconrel.2021.02.027","volume":"332","author":"I Seoane-Via\u00f1o","year":"2021","unstructured":"Seoane-Via\u00f1o I, Januskaite P, Alvarez-Lorenzo C, Basit AW, Goyanes A. Semi-solid extrusion 3D printing in drug delivery and biomedicine: Personalised solutions for healthcare challenges. J Controlled Release. 2021;332:367\u201389. https:\/\/doi.org\/10.1016\/j.jconrel.2021.02.027.","journal-title":"J Controlled Release"},{"issue":"1","key":"630_CR28","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s12247-024-09904-z","volume":"20","author":"R Rege","year":"2025","unstructured":"Rege R, Mellema T, Ramcharan A, Hoummad AA, Verhoeven S, Mishra V, Jansen AJ, Ouwerkerk N, Shokri F. 3D Drug Printing by Semi-Solid Extrusion Through Reusable Cartridges: Usability Evaluation. J Pharm Innov. 2025;20(1):21. https:\/\/doi.org\/10.1007\/s12247-024-09904-z.","journal-title":"J Pharm Innov"},{"issue":"5","key":"630_CR29","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1007\/s11095-021-03041-9","volume":"38","author":"Z Wang","year":"2021","unstructured":"Wang Z, Li J, Hong X, Han X, Liu B, Li X, Zhang H, Gao J, Liu N, Gao X, Zheng A. Taste masking study based on an electronic tongue: The formulation design of 3D printed levetiracetam instant-dissolving tablets. Pharm Res. 2021;38(5):831. https:\/\/doi.org\/10.1007\/s11095-021-03041-9.","journal-title":"Pharm Res"},{"key":"630_CR30","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.ejpb.2014.12.003","volume":"89","author":"A Goyanes","year":"2015","unstructured":"Goyanes A, Buanz AB, Hatton GB, Gaisford S, Basit AW. 3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets. Eur J Pharm Biopharm. 2015;89:157\u201362. https:\/\/doi.org\/10.1016\/j.ejpb.2014.12.003.","journal-title":"Eur J Pharm Biopharm"},{"issue":"3","key":"630_CR31","doi-asserted-by":"publisher","first-page":"282","DOI":"10.3390\/mi17030282","volume":"17","author":"S Antony Jose","year":"2026","unstructured":"Antony Jose S, Evtimow A, Menezes PL. Advances in 3D Bioprinting: Materials, Processes, and Emerging Applications. Micromachines. 2026;17(3):282. https:\/\/doi.org\/10.3390\/mi17030282.","journal-title":"Micromachines"},{"key":"630_CR32","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.5281\/zenodo.15921829","volume":"3","author":"Satyam","year":"2025","unstructured":"Satyam, Sharma. Dr. Sudha Rathod, Anjali Rai, Pharmaceutical Formulations Using 3D Printing: Advances and Challenges. Int J Pharm Sci. 2025;3:2066\u201372. https:\/\/doi.org\/10.5281\/zenodo.15921829.","journal-title":"Int J Pharm Sci"},{"key":"630_CR33","doi-asserted-by":"publisher","unstructured":"Shubhangi, Gaikwad, Directions. Int J Pharm Sci. 2025;3(5):1553\u201368. https:\/\/doi.org\/10.5281\/zenodo.15380932.","DOI":"10.5281\/zenodo.15380932"},{"issue":"4","key":"630_CR34","doi-asserted-by":"publisher","first-page":"441","DOI":"10.3390\/pharmaceutics16040441","volume":"16","author":"V Ianno","year":"2024","unstructured":"Ianno V, Vurpillot S, Prillieux S, Espeau P. Pediatric formulations developed by extrusion-based 3D printing: from past discoveries to future prospects. Pharmaceutics. 2024;16(4):441. https:\/\/doi.org\/10.3390\/pharmaceutics16040441.","journal-title":"Pharmaceutics"},{"issue":"3","key":"630_CR35","doi-asserted-by":"publisher","first-page":"192","DOI":"10.3390\/gels11030192","volume":"11","author":"B Uysal","year":"2025","unstructured":"Uysal B, Madduma-Bandarage US, Jayasinghe HG, Madihally S. 3D-Printed Hydrogels from Natural Polymers for Biomedical Applications: Conventional Fabrication Methods, Current Developments, Advantages, and Challenges. Gels. 2025;11(3):192. https:\/\/doi.org\/10.3390\/gels11030192.","journal-title":"Gels"},{"key":"630_CR36","doi-asserted-by":"publisher","unstructured":"Muehlenfeld C, Duffy P, Yang F, Zerme\u00f1o-P\u00e9rez D, Durig T. Polymers for Pharmaceutical 3D Printing: Printability and Critical Insight into Material Properties. In: 3D Printing: Emerging Technologies and Functionality of Polymeric Excipients in Drug Product Development. Cham: Springer International Publishing; 2023. p. 97\u2013137. https:\/\/doi.org\/10.1007\/978-3-031-46015-9_5.","DOI":"10.1007\/978-3-031-46015-9_5"},{"issue":"4","key":"630_CR37","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3390\/chemengineering5040078","volume":"5","author":"B Sabbatini","year":"2021","unstructured":"Sabbatini B, Cambriani A, Cespi M, Palmieri GF, Perinelli DR, Bonacucina G. An overview of natural polymers as reinforcing agents for 3D printing. ChemEngineering. 2021;5(4):78. https:\/\/doi.org\/10.3390\/chemengineering5040078.","journal-title":"ChemEngineering"},{"issue":"7","key":"630_CR38","doi-asserted-by":"publisher","DOI":"10.3390\/polym11071094","volume":"11","author":"V Mazzanti","year":"2019","unstructured":"Mazzanti V, Malagutti L, Mollica F. FDM 3D printing of polymers containing natural fillers: a review of their mechanical properties. Polymers. 2019;11(7):1094. https:\/\/doi.org\/10.3390\/polym11071094.","journal-title":"Polymers"},{"issue":"4","key":"630_CR39","doi-asserted-by":"publisher","first-page":"203","DOI":"10.3390\/pharmaceutics10040203","volume":"10","author":"DK Tan","year":"2018","unstructured":"Tan DK, Maniruzzaman M, Nokhodchi A. Advanced pharmaceutical applications of hot-melt extrusion coupled with fused deposition modelling (FDM) 3D printing for personalised drug delivery. Pharmaceutics. 2018;10(4):203. https:\/\/doi.org\/10.3390\/pharmaceutics10040203.","journal-title":"Pharmaceutics"},{"issue":"17","key":"630_CR40","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28176213","volume":"28","author":"M Oleksy","year":"2023","unstructured":"Oleksy M, Dynarowicz K, Aebisher D. Advances in biodegradable polymers and biomaterials for medical applications\u2014a review. Molecules. 2023;28(17):6213. https:\/\/doi.org\/10.3390\/molecules28176213.","journal-title":"Molecules"},{"key":"630_CR41","doi-asserted-by":"publisher","unstructured":"Tamariz E, Rios-Ram\u00edrez A. Biodegradation of medical purpose polymeric materials and their impact on biocompatibility. In: Biodegradation-Life of Science. Croatia: Intech; 2013. p. 1\u201329. https:\/\/doi.org\/10.5772\/56220.","DOI":"10.5772\/56220"},{"issue":"3","key":"630_CR42","doi-asserted-by":"publisher","first-page":"317","DOI":"10.3390\/pharmaceutics16030317","volume":"16","author":"C Muehlenfeld","year":"2024","unstructured":"Muehlenfeld C, Duffy P, Yang F, Zerme\u00f1o P\u00e9rez D, El-Saleh F, Durig T. Excipients in Pharmaceutical Additive Manufacturing: A Comprehensive Exploration of Polymeric Material Selection for Enhanced 3D Printing. Pharmaceutics. 2024;16(3):317. https:\/\/doi.org\/10.3390\/pharmaceutics16030317.","journal-title":"Pharmaceutics"},{"issue":"15","key":"630_CR43","doi-asserted-by":"publisher","first-page":"10212","DOI":"10.1021\/acs.chemrev.7b00074","volume":"117","author":"SC Igon","year":"2017","unstructured":"igon SC, Liska R, Stampfl J, Gurr M, M\u00fclhaupt R. Polymers for 3D printing and customized additive manufacturing. Chem Rev. 2017;117(15):10212\u201390. https:\/\/doi.org\/10.1021\/acs.chemrev.7b00074.","journal-title":"Chem Rev"},{"key":"630_CR44","doi-asserted-by":"publisher","first-page":"105619","DOI":"10.1016\/j.ejps.2020.105619","volume":"158","author":"L Viidik","year":"2021","unstructured":"Viidik L, Vesala J, Laitinen R, Korhonen O, Ketolainen J, Aruv\u00e4li J, Kirsim\u00e4e K, Kogermann K, Hein\u00e4m\u00e4ki J, Laidm\u00e4e I, Ervasti T. Preparation and characterization of hot-melt extruded polycaprolactone-based filaments intended for 3D-printing of tablets. Eur J Pharm Sci. 2021;158:105619. https:\/\/doi.org\/10.1016\/j.ejps.2020.105619.","journal-title":"Eur J Pharm Sci"},{"issue":"3","key":"630_CR45","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1039\/D2FB00043A","volume":"1","author":"S Suri","year":"2023","unstructured":"Suri S, Singh A. Modification of starch by novel and traditional ways: influence on the structure and functional properties. Sustainable Food Technology. 2023;1(3):348\u201362.","journal-title":"Sustainable Food Technology"},{"key":"630_CR46","unstructured":"American Chemical Supplier |. Benchchem [Internet]. www.benchchem.com. Available from: https:\/\/www.benchchem.com\/"},{"key":"630_CR47","unstructured":"BASF \u2013 India [Internet]. Basf.com. 2024. Available from: https:\/\/www.basf.com\/in\/en"},{"key":"630_CR48","unstructured":"An agency of the European. Union [Internet]. [cited 2026 Apr 8]. Available from: https:\/\/www.ema.europa.eu\/en\/documents\/annual-report\/annual-report-european-medicines-agency-2013_en.pdf"},{"key":"630_CR49","unstructured":"Wiley [Internet]. EFSA. 2024. Available from: https:\/\/efsa.onlinelibrary.wiley.com\/"},{"key":"630_CR50","unstructured":"Homepage_en [Internet]. Shin-Etsu Chemical Co., Ltd. Available from: https:\/\/www.shinetsu.co.jp\/en\/"},{"key":"630_CR51","unstructured":"European Directorate for the Quality of Medicines and Healthcare. - European Directorate for the Quality of Medicines & HealthCare - EDQM [Internet]. European Directorate for the Quality of Medicines & HealthCare. 2024 [cited 2026 Apr 8]. Available from: http:\/\/edqm.eu\/en\/european-pharmacopoeia-new-online-only-12th-edition"},{"key":"630_CR52","unstructured":"USP. U.S. Pharmacopeia [Internet]. Usp.org. 2019. Available from: https:\/\/www.usp.org\/"},{"key":"630_CR53","unstructured":"Evonik. - Leading Beyond Chemistry [Internet]. Evonik.com. 2024. Available from: https:\/\/www.evonik.com\/en.html"},{"key":"630_CR54","unstructured":"Welcome To Zscaler Directory Authentication [Internet]. Sigmaaldrich.com. 2026 [cited 2026 Apr 8]. Available from: https:\/\/www.sigmaaldrich.com\/IN\/en\/product\/aldrich\/914762"},{"key":"630_CR55","unstructured":"Gattefosse.com. 2020. Available from: https:\/\/www.gattefosse.com\/"},{"key":"630_CR56","unstructured":"Amorphous India [Internet]. AmorphousIndia. 2025 [cited 2026 Apr 8]. Available from: https:\/\/amorphousindia.com\/"},{"key":"630_CR57","unstructured":"The Journal of Silk Science and Technology of Japan [Internet]. Jst.go.jp. 2025 [cited 2026 Apr 8]. Available from: https:\/\/www.jstage.jst.go.jp\/browse\/silk\/25\/0\/_contents\/-char\/en"},{"key":"630_CR58","doi-asserted-by":"publisher","unstructured":"Thakker P, Shah J, Mehta T, Agarwal G. Taste Masking of Pharmaceutical Formulations: Review on Technologies, Recent Trends and Patents.(2020). Int. J. Life Sci. Pharma Res. 2020;10(3):P88-96. https:\/\/doi.org\/10.22376\/ijpbs\/lpr.2020.10.3.P88-96","DOI":"10.22376\/ijpbs\/lpr.2020.10.3.P88-96"},{"issue":"9","key":"630_CR59","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.3390\/pharmaceutics13091424","volume":"13","author":"J Dos Santos","year":"2021","unstructured":"Dos Santos J, da Silva GS, Velho MC, Beck RC. Eudragit\u00ae: A versatile family of polymers for hot melt extrusion and 3D printing processes in pharmaceutics. Pharmaceutics. 2021;13(9):1424. https:\/\/doi.org\/10.3390\/pharmaceutics13091424.","journal-title":"Pharmaceutics"},{"issue":"4","key":"630_CR60","doi-asserted-by":"publisher","first-page":"472","DOI":"10.3390\/pharmaceutics13040472","volume":"13","author":"S Roulon","year":"2021","unstructured":"Roulon S, Soulairol I, Lavastre V, Payre N, Cazes M, Delbreilh L, Ali\u00e9 J. Production of reproducible filament batches for the fabrication of 3D printed oral forms. Pharmaceutics. 2021;13(4):472. https:\/\/doi.org\/10.3390\/pharmaceutics13040472.","journal-title":"Pharmaceutics"},{"key":"630_CR61","unstructured":"Abdelhakim HE. Formulation and Assessment of Taste-masked Electrospun Fibre Mats for Paediatric Drug Delivery (Doctoral dissertation, UCL (University College London)). https:\/\/discovery.ucl.ac.uk\/id\/eprint\/10132872"},{"issue":"8","key":"630_CR62","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.3390\/pharmaceutics13081301","volume":"13","author":"AG Tabriz","year":"2021","unstructured":"Tabriz AG, Fullbrook DH, Vilain L, Derrar Y, Nandi U, Grau C, Morales A, Hooper G, Hiezl Z, Douroumis D. Personalised tasted masked chewable 3D printed fruit-chews for paediatric patients. Pharmaceutics. 2021;13(8):1301. https:\/\/doi.org\/10.3390\/pharmaceutics13081301.","journal-title":"Pharmaceutics"},{"issue":"44","key":"630_CR63","doi-asserted-by":"publisher","first-page":"49371","DOI":"10.1021\/acsami.0c12925","volume":"12","author":"E Andablo-Reyes","year":"2020","unstructured":"Andablo-Reyes E, Bryant M, Neville A, Hyde P, Sarkar R, Francis M, Sarkar A. 3D biomimetic tongue-emulating surfaces for tribological applications. ACS Appl Mater Interfaces. 2020;12(44):49371\u201385. https:\/\/doi.org\/10.1021\/acsami.0c12925.","journal-title":"ACS Appl Mater Interfaces"},{"key":"630_CR64","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111319","volume":"117","author":"J Junpha","year":"2020","unstructured":"Junpha J, Wisitsoraat A, Prathumwan R, Chaengsawang W, Khomungkhun K, Subannajui K. Electronic tongue and cyclic voltammetric sensors based on carbon nanotube\/polylactic composites fabricated by fused deposition modelling 3D printing. Mater Sci Eng C Mater Biol Appl. 2020;117:111319. https:\/\/doi.org\/10.1016\/j.msec.2020.111319.","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"issue":"8","key":"630_CR65","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.3390\/pharmaceutics14081732","volume":"14","author":"L Rodr\u00edguez-Pombo","year":"2022","unstructured":"Rodr\u00edguez-Pombo L, Awad A, Basit AW, Alvarez-Lorenzo C, Goyanes A. Innovations in chewable formulations: the novelty and applications of 3D printing in drug product design. Pharmaceutics. 2022;14(8):1732. https:\/\/doi.org\/10.3390\/pharmaceutics14081732.","journal-title":"Pharmaceutics"},{"issue":"2","key":"630_CR66","doi-asserted-by":"publisher","first-page":"rqad009","DOI":"10.1093\/rpsppr\/rqad009","volume":"2","author":"M Vlachou","year":"2023","unstructured":"Vlachou M, Siamidi A, Protopapa C, Sotiropoulou I. A review on the colours, flavours and shapes used in paediatric 3D printed oral solid dosage forms. RPS Pharm Pharmacol Rep. 2023;2(2):rqad009. https:\/\/doi.org\/10.1093\/rpsppr\/rqad009.","journal-title":"RPS Pharm Pharmacol Rep"},{"issue":"11","key":"630_CR67","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.3390\/pharmaceutics12111100","volume":"12","author":"P Januskaite","year":"2020","unstructured":"Januskaite P, Xu X, Ranmal SR, Gaisford S, Basit AW, Tuleu C, Goyanes A. I spy with my little eye: a paediatric visual preferences survey of 3D printed tablets. Pharmaceutics. 2020;12(11):1100. https:\/\/doi.org\/10.3390\/pharmaceutics12111100.","journal-title":"Pharmaceutics"},{"issue":"1","key":"630_CR68","doi-asserted-by":"publisher","first-page":"4875984","DOI":"10.1155\/2024\/4875984","volume":"2024","author":"AM Tegegne","year":"2024","unstructured":"Tegegne AM, Ayenew KD, Selam MN. Review on Recent Advance of 3DP-Based Pediatric Drug Formulations. Biomed Res Int. 2024;2024(1):4875984. https:\/\/doi.org\/10.1155\/2024\/4875984.","journal-title":"Biomed Res Int"},{"key":"630_CR69","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.jconrel.2016.05.034","volume":"234","author":"A Goyanes","year":"2016","unstructured":"Goyanes A, Det-Amornrat U, Wang J, Basit AW, Gaisford S. 3D scanning and 3D printing as innovative technologies for fabricating personalized topical drug delivery systems. J Controlled Release. 2016;234:41\u20138. https:\/\/doi.org\/10.1016\/j.jconrel.2016.05.034.","journal-title":"J Controlled Release"},{"issue":"2","key":"630_CR70","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1208\/s12249-016-0620-1","volume":"18","author":"H Wickstr\u00f6m","year":"2017","unstructured":"Wickstr\u00f6m H, Nyman JO, Indola M, Sundelin H, Kronberg L, Preis M, Rantanen J, Sandler N. Colorimetry as quality control tool for individual inkjet-printed pediatric formulations. AAPS PharmSciTech. 2017;18(2):293\u2013302. https:\/\/doi.org\/10.1208\/s12249-016-0620-1.","journal-title":"AAPS PharmSciTech"},{"key":"630_CR71","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2025.125645","volume":"677","author":"A Imbriano","year":"2025","unstructured":"Imbriano A, Fratini C, Bondi G, D\u2019Abbrunzo I, Bertoni S, Tiboni M, et al. 3D-printed chewable gummy tablets: a new tool for oral amoxicillin administration in paediatric population. Int J Pharm. 2025;125645. https:\/\/doi.org\/10.1016\/j.ijpharm.2025.125645.","journal-title":"Int J Pharm"},{"issue":"4","key":"630_CR72","doi-asserted-by":"publisher","first-page":"435","DOI":"10.3390\/ph15040435","volume":"15","author":"AM Malebari","year":"2022","unstructured":"Malebari AM, Kara A, Khayyat AN, Mohammad KA, Serrano DR. Development of advanced 3D-printed solid dosage pediatric formulations for HIV treatment. Pharmaceuticals. 2022;15(4):435. https:\/\/doi.org\/10.3390\/ph15040435.","journal-title":"Pharmaceuticals"},{"issue":"10","key":"630_CR73","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.3390\/pharmaceutics16101338","volume":"16","author":"M Magari\u00f1os-Trivi\u00f1o","year":"2024","unstructured":"Magari\u00f1os-Trivi\u00f1o M, D\u00edaz-Torres E, Su\u00e1rez-Gonz\u00e1lez J, Santove\u00f1a-Est\u00e9vez A, Fari\u00f1a JB. The Design of Novel 3D-Printed, Moulded, and Oral Viscous Budesonide Formulations for Paediatrics: A Comparative Evaluation of Their Mucoadhesive Properties. Pharmaceutics. 2024;16(10):1338. https:\/\/doi.org\/10.3390\/pharmaceutics16101338.","journal-title":"Pharmaceutics"},{"key":"630_CR74","doi-asserted-by":"publisher","first-page":"105291","DOI":"10.1016\/j.ejps.2020.105291","volume":"147","author":"C Karavasili","year":"2020","unstructured":"Karavasili C, Gkaragkounis A, Moschakis T, Ritzoulis C, Fatouros DG. Pediatric-friendly chocolate-based dosage forms for the oral administration of both hydrophilic and lipophilic drugs fabricated with extrusion-based 3D printing. Eur J Pharm Sci. 2020;147:105291. https:\/\/doi.org\/10.1016\/j.ejps.2020.105291.","journal-title":"Eur J Pharm Sci"},{"issue":"3","key":"630_CR75","doi-asserted-by":"publisher","first-page":"187","DOI":"10.3390\/gels11030187","volume":"11","author":"A Bia\u0142ek","year":"2025","unstructured":"Bia\u0142ek A, Krysztofiak J, Hozakowska A, Wojszel Z, Osma\u0142ek T, Wojty\u0142ko M, Froelich A. Novel Soft Dosage Forms for Paediatric Applications: Can We 3D-Print Them or Not? Gels. 2025;11(3):187. https:\/\/doi.org\/10.3390\/gels11030187.","journal-title":"Gels"},{"issue":"3","key":"630_CR76","doi-asserted-by":"publisher","first-page":"385","DOI":"10.3390\/pharmaceutics16030385","volume":"16","author":"C Protopapa","year":"2024","unstructured":"Protopapa C, Siamidi A, Kolipaka SS, Junqueira LA, Douroumis D, Vlachou M. In vitro profile of hydrocortisone release from three-dimensionally printed paediatric mini-tablets. Pharmaceutics. 2024;16(3):385. https:\/\/doi.org\/10.3390\/pharmaceutics16030385.","journal-title":"Pharmaceutics"},{"key":"630_CR77","doi-asserted-by":"publisher","first-page":"123131","DOI":"10.1016\/j.ijpharm.2023.123131","volume":"642","author":"C Parulski","year":"2023","unstructured":"Parulski C, Bya LA, Goebel J, Servais AC, Lechanteur A, Evrard B. Development of 3D printed mini-waffle shapes containing hydrocortisone for children personalized medicine. Int J Pharm. 2023;642:123131. https:\/\/doi.org\/10.1016\/j.ijpharm.2023.123131.","journal-title":"Int J Pharm"},{"key":"630_CR78","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ejps.2014.11.009","volume":"68","author":"J Skowyra","year":"2015","unstructured":"Skowyra J, Pietrzak K, Alhnan MA. Fabrication of extended-release patient-tailored prednisolone tablets via fused deposition modelling (FDM) 3D printing. Eur J Pharm Sci. 2015;68:11\u20137. https:\/\/doi.org\/10.1016\/j.ejps.2014.11.009.","journal-title":"Eur J Pharm Sci"},{"key":"630_CR79","doi-asserted-by":"publisher","first-page":"119687","DOI":"10.1016\/j.ijpharm.2020.119687","volume":"587","author":"H Herrada-Manch\u00f3n","year":"2020","unstructured":"Herrada-Manch\u00f3n H, Rodr\u00edguez-Gonz\u00e1lez D, Fern\u00e1ndez MA, Su\u00f1\u00e9-Pou M, P\u00e9rez-Lozano P, Garc\u00eda-Montoya E, Aguilar E. 3D printed gummies: Personalized drug dosage in a safe and appealing way. Int J Pharm. 2020;587:119687. https:\/\/doi.org\/10.1016\/j.ijpharm.2020.119687.","journal-title":"Int J Pharm"},{"issue":"6","key":"630_CR80","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1007\/s11095-018-2405-6","volume":"35","author":"W Kempin","year":"2018","unstructured":"Kempin W, Domsta V, Grathoff G, Brecht I, Semmling B, Tillmann S, Weitschies W, Seidlitz A. Immediate Release 3D-Printed Tablets Produced Via Fused Deposition Modeling of a Thermo-Sensitive Drug: Kempin. Pharm Res. 2018;35(6):124. https:\/\/doi.org\/10.1007\/s11095-018-2405-6.","journal-title":"Pharm Res"},{"key":"630_CR81","doi-asserted-by":"publisher","first-page":"120854","DOI":"10.1016\/j.ijpharm.2021.120854","volume":"605","author":"DT Eduardo","year":"2021","unstructured":"Eduardo DT, Ana SE. A micro-extrusion 3D printing platform for fabrication of orodispersible printlets for pediatric use. Int J Pharm. 2021;605:120854. https:\/\/doi.org\/10.1016\/j.ijpharm.2021.120854","journal-title":"Int J Pharm"},{"key":"630_CR82","doi-asserted-by":"publisher","first-page":"100123","DOI":"10.1016\/j.stlm.2023.100123","volume":"12","author":"O Koshovyi","year":"2023","unstructured":"Koshovyi O, Hein\u00e4m\u00e4ki J, Laidm\u00e4e I, Topelius NS, Grytsyk A, Raal A. Semi-solid extrusion 3D-printing of eucalypt extract-loaded polyethylene oxide gels intended for pharmaceutical applications. Annals 3D Print Med. 2023;12:100123. https:\/\/doi.org\/10.1016\/j.stlm.2023.100123.","journal-title":"Annals 3D Print Med"},{"issue":"1","key":"630_CR83","doi-asserted-by":"publisher","DOI":"10.1186\/s41205-019-0039-x","volume":"5","author":"AR Johnson","year":"2019","unstructured":"Johnson AR, Procopio AT. Low cost additive manufacturing of microneedle masters. 3D Print Med. 2019;5(1):2. https:\/\/doi.org\/10.1186\/s41205-019-0039-x.","journal-title":"3D Print Med"},{"issue":"1","key":"630_CR84","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.jsps.2011.12.002","volume":"21","author":"JG Hiremath","year":"2013","unstructured":"Hiremath JG, Khamar NS, Palavalli SG, Rudani CG, Aitha R, Mura P. Paclitaxel loaded carrier based biodegradable polymeric implants: Preparation and in vitro characterization. Saudi Pharm J. 2013;21(1):85\u201391. https:\/\/doi.org\/10.1016\/j.jsps.2011.12.002.","journal-title":"Saudi Pharm J"},{"key":"630_CR85","doi-asserted-by":"publisher","first-page":"103343","DOI":"10.1016\/j.addma.2022.103343","volume":"61","author":"W Huang","year":"2023","unstructured":"Huang W, Zhang J, Singh V, Xu L, Kabi P, Bele E, Tiwari MK. Digital light 3D printing of a polymer composite featuring robustness, self-healing, recyclability and tailorable mechanical properties. Additive Manuf. 2023;61:103343. https:\/\/doi.org\/10.1016\/j.addma.2022.103343.","journal-title":"Additive Manuf"},{"issue":"2","key":"630_CR86","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1039\/D3LP00207A","volume":"2","author":"\u013d Hod\u00e1sov\u00e1","year":"2024","unstructured":"Hod\u00e1sov\u00e1 \u013d, Isarn I, Bravo F, Alem\u00e1n C, Borr\u00e0s N, Fargas G, Armelin E. Synthesis of bio-sourced liquid resins and their photopolymerization with poly (ethylene glycol) diacrylate in the roadmap to more sustainable digital light processing technologies. RSC Appl Polym. 2024;2(2):284\u201395. https:\/\/doi.org\/10.1039\/D3LP00207A.","journal-title":"RSC Appl Polym"},{"issue":"2","key":"630_CR87","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.ijpharm.2017.11.016","volume":"544","author":"J Holl\u00e4nder","year":"2018","unstructured":"Holl\u00e4nder J, Hakala R, Suominen J, Moritz N, Yliruusi J, Sandler N. 3D printed UV light cured polydimethylsiloxane devices for drug delivery. Int J Pharm. 2018;544(2):433\u201342. https:\/\/doi.org\/10.1016\/j.ijpharm.2017.11.016.","journal-title":"Int J Pharm"},{"issue":"12","key":"630_CR88","doi-asserted-by":"publisher","first-page":"630","DOI":"10.3390\/pharmaceutics11120630","volume":"11","author":"K Rycerz","year":"2019","unstructured":"Rycerz K, Stepien KA, Czapiewska M, Arafat BT, Habashy R, Isreb A, Peak M, Alhnan MA. Embedded 3D printing of novel bespoke soft dosage form concept for pediatrics. Pharmaceutics. 2019;11(12):630. https:\/\/doi.org\/10.3390\/pharmaceutics11120630.","journal-title":"Pharmaceutics"},{"key":"630_CR89","doi-asserted-by":"publisher","unstructured":"Khalid GM, Selmin F. Applications of alginates in the design and preparation of orodispersible dosage forms. In: Properties and applications of alginates. IntechOpen; 2021. p. 1\u201313. https:\/\/doi.org\/10.1080\/03639045.2021.1908335.","DOI":"10.1080\/03639045.2021.1908335"},{"issue":"7","key":"630_CR90","doi-asserted-by":"publisher","first-page":"334","DOI":"10.3390\/pharmaceutics11070334","volume":"11","author":"H \u00d6blom","year":"2019","unstructured":"\u00d6blom H, Sj\u00f6holm E, Rautamo M, Sandler N. Towards printed pediatric medicines in hospital pharmacies: comparison of 2D and 3D-printed orodispersible warfarin films with conventional oral powders in unit dose sachets. Pharmaceutics. 2019;11(7):334. https:\/\/doi.org\/10.3390\/pharmaceutics11070334.","journal-title":"Pharmaceutics"},{"issue":"2","key":"630_CR91","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1007\/s11095-017-2284-2","volume":"35","author":"N Scoutaris","year":"2018","unstructured":"Scoutaris N, Ross SA, Douroumis D. 3D printed Starmix drug loaded dosage forms for paediatric applications. Pharm Res. 2018;35(2):34. https:\/\/doi.org\/10.1007\/s11095-017-2284-2.","journal-title":"Pharm Res"},{"issue":"1","key":"630_CR92","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/s43094-022-00439-z","volume":"8","author":"R Pawar","year":"2022","unstructured":"Pawar R, Pawar A. 3D printing of pharmaceuticals: approach from bench scale to commercial development. Future J Pharm Sci. 2022;8(1):48. https:\/\/doi.org\/10.1186\/s43094-022-00439-z.","journal-title":"Future J Pharm Sci"},{"issue":"9","key":"630_CR93","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1080\/03639045.2020.1801714","volume":"46","author":"M Wallis","year":"2020","unstructured":"Wallis M, Al-Dulimi Z, Tan DK, Maniruzzaman M, Nokhodchi A. 3D printing for enhanced drug delivery: current state-of-the-art and challenges. Drug Dev Ind Pharm. 2020;46(9):1385\u2013401. https:\/\/doi.org\/10.1080\/03639045.2020.1801714.","journal-title":"Drug Dev Ind Pharm"},{"issue":"7","key":"630_CR94","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.3390\/pharmaceutics15071877","volume":"15","author":"K Huanbutta","year":"2023","unstructured":"Huanbutta K, Burapapadh K, Sriamornsak P, Sangnim T. Practical application of 3D printing for pharmaceuticals in hospitals and pharmacies. Pharmaceutics. 2023;15(7):1877. https:\/\/doi.org\/10.3390\/pharmaceutics15071877.","journal-title":"Pharmaceutics"},{"issue":"6","key":"630_CR95","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1007\/s43441-021-00354-0","volume":"56","author":"J Quodbach","year":"2022","unstructured":"Quodbach J, Bogdahn M, Breitkreutz J, Chamberlain R, Eggenreich K, Elia AG, Gottschalk N, Gunkel-Grabole G, Hoffmann L, Kapote D, Kipping T. Quality of FDM 3D printed medicines for pediatrics: considerations for formulation development, filament extrusion, printing process and printer design. Therapeutic Innov Regul Sci. 2022;56(6):910\u201328. https:\/\/doi.org\/10.1007\/s43441-021-00354-0.","journal-title":"Therapeutic Innov Regul Sci"},{"key":"630_CR96","unstructured":"Research C. for DE and. Pediatric Research Equity Act | PREA. FDA [Internet]. 2019; Available from: https:\/\/www.fda.gov\/drugs\/development-resources\/pediatric-research-equity-act-prea"},{"key":"630_CR97","unstructured":"EuPFI [Internet]. Eupfi.co.uk. 2025. Available from: https:\/\/eupfi.co.uk\/"},{"key":"630_CR98","unstructured":"Research C. for DE and. Best Pharmaceuticals for Children Act (BPCA). FDA [Internet]. 2019; Available from: https:\/\/www.fda.gov\/drugs\/development-resources\/best-pharmaceuticals-children-act-bpca"},{"key":"630_CR99","unstructured":"Research C, for DE. and. CDER\u2019s Framework for Regulatory Advanced Manufacturing Evaluation (FRAME) Initiative. FDA [Internet]. 2023; Available from: https:\/\/www.fda.gov\/about-fda\/center-drug-evaluation-and-research-cder\/cders-framework-regulatory-advanced-manufacturing-evaluation-frame-initiative"},{"key":"630_CR100","unstructured":"GastroPlus X. 2 - Simulations Plus [Internet]. Simulations Plus. 2026 [cited 2026 Apr 8]. Available from: https:\/\/www.simulations-plus.com\/gastroplusx\/"}],"container-title":["DARU Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40199-026-00630-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40199-026-00630-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40199-026-00630-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T20:03:58Z","timestamp":1785441838000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40199-026-00630-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":100,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["630"],"URL":"https:\/\/doi.org\/10.1007\/s40199-026-00630-0","relation":{},"ISSN":["2008-2231"],"issn-type":[{"value":"2008-2231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]},"assertion":[{"value":"20 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"52"}}