{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:08:35Z","timestamp":1793138915364,"version":"4.5.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100006470","name":"Aristotle University of Thessaloniki","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006470","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuropsychiatr"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The influence of stressful life events on general cognition and for the first time on financial capacity performance of patients with a\u00a0diagnosis of Alzheimer\u2019s disease (AD) and in healthy controls (HC) is assessed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A total of 268\u00a0participants (122\u00a0patients and 146 HCs with similar demographics) were examined with a\u00a0number of neuropsychological tests, including Mini Mental State Examination (MMSE), Geriatric Depression Scale (GDS-15), and Legal Capacity for Property Law Transactions Assessment Scale (LCPLTAS) for measuring financial capacity. The life change unit (LCU) method was also used.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>HCs reported more stressful events than AD patients before the onset of the disease as the LCU load was higher for them (51.80 vs. 27.50), but in both groups the level of LCU load was far below 100, which is the threshold suggested for the induction of a\u00a0psychosomatic disorder. The most frequently reported life event for AD patients was increased family arguments (<jats:italic>n<\/jats:italic>\u202f=\u200945\/122), followed by increase in responsibilities (<jats:italic>n<\/jats:italic>\u202f=\u200932\/122) and financial difficulties (<jats:italic>n<\/jats:italic>\u202f=\u200929\/122), while the HC group reported problems within the family (<jats:italic>n<\/jats:italic>\u202f=\u200956\/146), change in health status (<jats:italic>n<\/jats:italic>\u202f=\u200932\/146), and a\u00a0death of a\u00a0beloved family member (<jats:italic>n<\/jats:italic>\u202f=\u200927\/146). Regressions indicate no causal role for recent life events in the etiopathogenesis of AD, but an influence only of MMSE and diagnosis on financial capacity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Stressful life events do not seem to be important in financial capacity and relevant vulnerability to financial exploitation for either HCs or AD patients; therefore clinicians should not consider them per se as a\u00a0possible aggravating factor for financial deficits.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s40211-022-00451-y","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T17:13:50Z","timestamp":1672852430000},"page":"76-79","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Stressful life events, general cognitive performance, and financial capacity in healthy older adults and Alzheimer\u2019s disease patients","Belastende Lebensereignisse, allgemeine kognitive Leistung und finanzielle Kompetenzen bei gesunden \u00e4lteren Erwachsenen und Alzheimer-Patienten"],"prefix":"10.1007","volume":"37","author":[{"given":"Vaitsa","family":"Giannouli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda","family":"Tsolaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"451_CR1","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.psychres.2011.05.011","volume":"190","author":"KN Fountoulakis","year":"2011","unstructured":"Fountoulakis\u00a0KN, Pavlidis\u00a0I, Tsolaki\u00a0M. Life events and dementia: what is the nature of their relationship? Psychiatry Res. 2011;190:156\u20138.","journal-title":"Psychiatry Res"},{"key":"451_CR2","doi-asserted-by":"publisher","first-page":"1828","DOI":"10.1080\/13607863.2019.1625304","volume":"24","author":"K Nabe-Nielsen","year":"2020","unstructured":"Nabe-Nielsen\u00a0K, Rod\u00a0NH, Hansen \u00c5M, Prescott\u00a0E, Grynderup\u00a0MB, Islamoska\u00a0S, Westendorp\u00a0RG. Perceived stress and dementia: results from the Copenhagen city heart study. Aging Ment Health. 2020;24:1828\u201336.","journal-title":"Aging Ment Health"},{"key":"451_CR3","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1017\/S1041610213001804","volume":"26","author":"A Sundstr\u00f6m","year":"2014","unstructured":"Sundstr\u00f6m\u00a0A, R\u00f6nnlund\u00a0M, Adolfsson\u00a0R, Nilsson\u00a0L\u2011G. Stressful life events are not associated with the development of dementia. Int Psychogeriatr. 2014;26:147\u201354.","journal-title":"Int Psychogeriatr"},{"key":"451_CR4","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.psychres.2009.06.001","volume":"176","author":"M Tsolaki","year":"2010","unstructured":"Tsolaki\u00a0M, Papaliagkas\u00a0V, Kounti\u00a0F, Messini\u00a0C, Boziki\u00a0M, Anogianakis\u00a0G, Vlaikidis\u00a0N. Severely stressful events and dementia: A study of an elderly Greek demented population. Psychiatry Res. 2010;176:51\u20134.","journal-title":"Psychiatry Res"},{"issue":"7","key":"451_CR5","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/j.jagp.2017.02.009","volume":"25","author":"L Gerritsen","year":"2017","unstructured":"Gerritsen\u00a0L, Wang\u00a0HX, Reynolds\u00a0CA, Fratiglioni\u00a0L, Gatz\u00a0M, Pedersen\u00a0NL. Influence of negative life events and widowhood on risk for dementia. Am J Geriatr Psychiatry. 2017;25(7):766\u201378.","journal-title":"Am J Geriatr Psychiatry"},{"issue":"1","key":"451_CR6","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1097\/WAD.0000000000000374","volume":"35","author":"V Giannouli","year":"2021","unstructured":"Giannouli\u00a0V, Tsolaki\u00a0M. Vascular dementia, depression and financial capacity assessment. Alzheimer Dis Assoc Disord. 2021;35(1):84\u20137.","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"451_CR7","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.3233\/JAD-170812","volume":"62","author":"V Giannouli","year":"2018","unstructured":"Giannouli\u00a0V, Stamovlasis\u00a0D, Tsolaki\u00a0M. Exploring the role of cognitive factors in a\u00a0new instrument for elders\u2019 financial capacity assessment. 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Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}