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Die Pr\u00e4valenz liegt bei bis zu 30\u202f%. Aufgrund einer stark zunehmenden Inzidenz weltweiter Demenzerkrankungen und einer geringen Anzahl randomisierter kontrollierter Studien hinsichtlich der Behandlung repetitiver Vokalisationen, soll dieses systematische Review eine Zusammenfassung existierender Arbeiten \u00fcber die Effektivit\u00e4t m\u00f6glicher pharmakotherapeutischer und nicht pharmakologischer Therapien geben.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methoden<\/jats:title>\n                    <jats:p>Das systematische Review basiert auf den PRISMA-Richtlinien und die Anmeldung erfolgte auf der Registrierungsseite PROSPERO (Registriernummer: CRD42023486344). Die Literaturrecherche fand in den Datenbanken PubMed und Embase statt. Aufgrund einer mangelnden Datenlage wurden ebenfalls Fallberichte eingeschlossen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>Von 2635 relevanten Artikeln wurden 25 Arbeiten in das Review inkludiert. Es konnte f\u00fcr SSRI, Pregabalin, Gabapentin und f\u00fcr die Antipsychotika Haloperidol und Risperidon anhand von wenigen Fallberichten eine Wirksamkeit belegt werden, die allerdings mit Nebenwirkungen behaftet war. Nicht pharmakologische Interventionen zeigten sich ebenfalls wirksam.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Schlussfolgerung<\/jats:title>\n                    <jats:p>Medikament\u00f6se und nichtmedikament\u00f6se Interventionen sind wirksame Behandlungsans\u00e4tze hinsichtlich repetitiver Vokalisationen bei Demenzerkrankten. Aufgrund der Tatsache, dass kaum randomisiert-kontrollierte Studien vorliegen, m\u00fcssen die Ergebnisse dieses systematischen Reviews mit Vorsicht interpretiert werden. Die Ergebnisse dieses Reviews zeigen, dass bei vielen Interventionen randomisiert-kontrollierte Studien zu fordern sind.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40211-024-00511-5","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T13:02:04Z","timestamp":1728997324000},"page":"174-183","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Therapiestrategien von repetitiven Vokalisationen bei Demenz","Therapy strategies for repetitive vocalizations in dementia"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5311-2109","authenticated-orcid":false,"given":"Samuel","family":"Taubenheim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnim","family":"Quante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"511_CR1","unstructured":"Medizinprodukte BfAu. 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