{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T18:15:10Z","timestamp":1788372910882,"version":"build-2803163510"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T00:00:00Z","timestamp":1532390400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Am J Clin Dermatol"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1007\/s40257-018-0374-5","type":"journal-article","created":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T02:46:45Z","timestamp":1532400405000},"page":"771-777","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Serum Zinc Levels in Hidradenitis Suppurativa: A Case\u2013Control Study"],"prefix":"10.1007","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3343-2630","authenticated-orcid":false,"given":"In\u00e9s","family":"Poveda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Vilarrasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Martorell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Javier","family":"Garc\u00eda-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Manuel","family":"Segura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Hisp\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"S\u00e1nchez-Pay\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Jos\u00e9","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8279-215X","authenticated-orcid":false,"given":"Jos\u00e9 Carlos","family":"Pascual","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,7,24]]},"reference":[{"issue":"5 Suppl 1","key":"374_CR1","doi-asserted-by":"publisher","first-page":"S8","DOI":"10.1016\/j.jaad.2015.07.045","volume":"73","author":"E Prens","year":"2015","unstructured":"Prens E, Deckers I. Pathophysiology of hidradenitis suppurativa: an update. J Am Acad Dermatol. 2015;73(5 Suppl 1):S8\u201311.","journal-title":"J Am Acad Dermatol"},{"key":"374_CR2","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.12688\/f1000research.11337.1","volume":"6","author":"MK Smith","year":"2017","unstructured":"Smith MK, Nicholson CL, Parks-Miller A, Hamzavi IH. Hidradenitis suppurativa: an update on connecting the tracts. F1000Research. 2017;6:1272.","journal-title":"F1000Research"},{"issue":"4","key":"374_CR3","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.jaad.2008.06.020","volume":"59","author":"J Revuz","year":"2008","unstructured":"Revuz J, Canoui-Poitrine F, Wolkenstein P, et al. Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol. 2008;59(4):596\u2013601.","journal-title":"J Am Acad Dermatol"},{"issue":"5 Suppl 1","key":"374_CR4","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1016\/j.jaad.2015.07.052","volume":"73","author":"GB Jemec","year":"2015","unstructured":"Jemec GB, Kimball AB. Hidradenitis suppurativa: epidemiology and scope of the problem. J Am Acad Dermatol. 2015;73(5 Suppl 1):S4\u20137. \n                    https:\/\/doi.org\/10.1016\/j.jaad.2015.07.052\n                    \n                  .","journal-title":"J Am Acad Dermatol"},{"key":"374_CR5","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1007\/978-3-540-33101-8_8","volume-title":"Hidradenitis suppurativa","author":"L Naldi","year":"2006","unstructured":"Naldi L. Epidemiology. In: Jemec G, Revuz J, Leyden J, editors. Hidradenitis suppurativa. 1st ed. Heidelberg: Springer; 2006. p. 58\u201364.","edition":"1"},{"issue":"5","key":"374_CR6","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1111\/bjd.14024","volume":"173","author":"T Tzellos","year":"2015","unstructured":"Tzellos T, Zouboulis CC, Gulliver W, Cohen AD, Wolkenstein P, Jemec GB. Cardiovascular disease risk factors in patients with hidradenitis suppurativa: a systematic review and meta-analysis of observational studies. Br J Dermatol. 2015;173(5):1142\u201355. \n                    https:\/\/doi.org\/10.1111\/bjd.14024\n                    \n                  .","journal-title":"Br J Dermatol"},{"issue":"4","key":"374_CR7","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.jaad.2013.11.014","volume":"70","author":"DA Gold","year":"2014","unstructured":"Gold DA, Reeder VJ, Mahan MG, Hamzavi IH. The prevalence of metabolic syndrome in patients with hidradenitis suppurativa. J Am Acad Dermatol. 2014;70(4):699\u2013703. \n                    https:\/\/doi.org\/10.1016\/j.jaad.2013.11.014\n                    \n                  .","journal-title":"J Am Acad Dermatol"},{"issue":"7","key":"374_CR8","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1111\/jdv.14076","volume":"31","author":"JC Pascual","year":"2017","unstructured":"Pascual JC, Gonz\u00e1lez I, Corona D, et al. Assessment of subclinical atherosclerosis in hidradenitis suppurativa. J Eur Acad Dermatol Venereol. 2017;31(7):1229\u201338. \n                    https:\/\/doi.org\/10.1111\/jdv.14076\n                    \n                  .","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"2","key":"374_CR9","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.jaad.2016.03.025","volume":"75","author":"MA Gonz\u00e1lez-L\u00f3pez","year":"2016","unstructured":"Gonz\u00e1lez-L\u00f3pez MA, Hern\u00e1ndez JL, Lacalle M, et al. Increased prevalence of subclinical atherosclerosis in patients with hidradenitis suppurativa (HS). J Am Acad Dermatol. 2016;75(2):329\u201335. \n                    https:\/\/doi.org\/10.1016\/j.jaad.2016.03.025\n                    \n                  .","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"374_CR10","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1111\/jdv.12567","volume":"29","author":"E Shavit","year":"2015","unstructured":"Shavit E, Dreiher J, Freud T, Halevy S, Vinker S, Cohen AD. Psychiatric comorbidities in 3207 patients with hidradenitis suppurativa. J Eur Acad Dermatol Venereol. 2015;29(2):371\u20136. \n                    https:\/\/doi.org\/10.1111\/jdv.12567\n                    \n                  .","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"1","key":"374_CR11","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jid.2017.09.008","volume":"138","author":"L Thorlacius","year":"2018","unstructured":"Thorlacius L, Cohen AD, Gislason GH, Jemec GB, Egeberg A. Increased suicide risk in patients with hidradenitis suppurativa. J Invest Dermatol. 2018;138(1):52\u20137. \n                    https:\/\/doi.org\/10.1016\/j.jid.2017.09.008\n                    \n                  .","journal-title":"J Invest Dermatol."},{"issue":"1","key":"374_CR12","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.det.2015.08.004","volume":"34","author":"G Kelly","year":"2016","unstructured":"Kelly G, Prens EP. Inflammatory mechanisms in hidradenitis suppurativa. Dermatol Clin. 2016;34(1):51\u20138. \n                    https:\/\/doi.org\/10.1016\/j.det.2015.08.004\n                    \n                  .","journal-title":"Dermatol Clin"},{"issue":"4","key":"374_CR13","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1111\/jdv.12966","volume":"29","author":"CC Zouboulis","year":"2015","unstructured":"Zouboulis CC, Desai N, Emtesmat L, et al. European S1 guideline for the treatment of hidradenitis suppurativa\/acne inversa. J Eur Acad Dermatol Venereol. 2015;29(4):619\u201344. \n                    https:\/\/doi.org\/10.1111\/jdv.12966\n                    \n                  .","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"2","key":"374_CR14","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1111\/ced.13278","volume":"43","author":"PT Riis","year":"2018","unstructured":"Riis PT, Ring HC, Kjaersgaard Andersen R, Jemec GB. Self-reported minor infections in patients with hidradenitis suppurativa and healthy controls. Clin Exp Dermatol. 2018;43(2):144\u20138. \n                    https:\/\/doi.org\/10.1111\/ced.13278\n                    \n                  .","journal-title":"Clin Exp Dermatol"},{"issue":"10","key":"374_CR15","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1111\/ijd.12550","volume":"53","author":"G Kelly","year":"2014","unstructured":"Kelly G, Sweeney CM, Tobin AM, Kirby B. Hidradenitis suppurativa: the role of immune dysregulation. Int J Dermatol. 2014;53(10):1186\u201396. \n                    https:\/\/doi.org\/10.1111\/ijd.12550\n                    \n                  .","journal-title":"Int J Dermatol"},{"issue":"2","key":"374_CR16","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1001\/archdermatol.2011.315","volume":"148","author":"B Dr\u00e9no","year":"2012","unstructured":"Dr\u00e9no B, Khammari A, Brocard A, et al. Hidradenitis suppurativa: the role of deficient cutaneous innate immunity. Arch Dermatol. 2012;148(2):182\u20136. \n                    https:\/\/doi.org\/10.1001\/archdermatol.2011.315\n                    \n                  .","journal-title":"Arch Dermatol"},{"issue":"4","key":"374_CR17","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.3305\/nh.2013.28.4.6606","volume":"28","author":"AM Ramos-Levi","year":"2013","unstructured":"Ramos-Levi AM, S\u00e1nchez-Pernaute A, Rubio-Herrera MA. Dermatitis and optic neuropathy due to zinc deficiency after malabsortive bariatric surgery. Nutr Hosp. 2013;28(4):1345\u20137. \n                    https:\/\/doi.org\/10.3305\/nh.2013.28.4.6606\n                    \n                  .","journal-title":"Nutr Hosp"},{"issue":"4","key":"374_CR18","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1159\/000100883","volume":"214","author":"A Brocard","year":"2007","unstructured":"Brocard A, Knol AC, Khammari A, Dr\u00e9no B. Hidradenitis suppurativa and zinc: a new therapeutic approach. A pilot study. Dermatology. 2007;214(4):325\u20137.","journal-title":"Dermatology"},{"issue":"10","key":"374_CR19","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1111\/j.1468-3083.2010.03934.x","volume":"25","author":"A Brocard","year":"2011","unstructured":"Brocard A, Dr\u00e9no B. Innate immunity: a crucial target for zinc in the treatment of inflammatory dermatosis. J Eur Acad Dermatol Venereol. 2011;25(10):1146\u201352. \n                    https:\/\/doi.org\/10.1111\/j.1468-3083.2010.03934.x\n                    \n                  .","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"3","key":"374_CR20","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.det.2010.03.006","volume":"28","author":"YS Bae","year":"2010","unstructured":"Bae YS, Hill ND, Bibi Y, Dreiher J, Cohen AD. Innovative uses for zinc in dermatology. Dermatol Clin. 2010;28(3):587\u201397. \n                    https:\/\/doi.org\/10.1016\/j.det.2010.03.006\n                    \n                  .","journal-title":"Dermatol Clin"},{"issue":"2","key":"374_CR21","doi-asserted-by":"publisher","first-page":"99","DOI":"10.3109\/15569527.2013.808656","volume":"33","author":"P Ozuguz","year":"2014","unstructured":"Ozuguz P, Dogruk Kacar S, Ekiz O, Takci Z, Balta I, Kalkan G. Evaluation of serum vitamins A and E and zinc levels according to the severity of acne vulgaris. Cutan Ocul Toxicol. 2014;33(2):99\u2013102. \n                    https:\/\/doi.org\/10.3109\/15569527.2013.808656\n                    \n                  .","journal-title":"Cutan Ocul Toxicol."},{"issue":"8","key":"374_CR22","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1111\/j.1365-4362.1982.tb03188.x","volume":"21","author":"M Amer","year":"1982","unstructured":"Amer M, Bahgat MR, Tosson Z, Abdel Mowla MY, Amer K. Serum zinc in acne vulgaris. Int J Dermatol. 1982;21(8):481\u20134.","journal-title":"Int J Dermatol"},{"issue":"6","key":"374_CR23","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1002\/biof.1386","volume":"43","author":"R Giacconi","year":"2017","unstructured":"Giacconi R, Cai L, Costarelli L, et al. Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy. BioFactors. 2017;43(6):770\u201384. \n                    https:\/\/doi.org\/10.1002\/biof.1386\n                    \n                  .","journal-title":"BioFactors"},{"issue":"12","key":"374_CR24","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1016\/j.biopsych.2013.05.008","volume":"74","author":"W Swardfager","year":"2013","unstructured":"Swardfager W, Herrmann N, Mazereeuw G, Goldberger K, Harimoto T, Lanct\u00f4t KL. Zinc in depression: a meta-analysis. Biol Psychiatry. 2013;74(12):872\u20138. \n                    https:\/\/doi.org\/10.1016\/j.biopsych.2013.05.008\n                    \n                  .","journal-title":"Biol Psychiatry"},{"key":"374_CR25","doi-asserted-by":"publisher","first-page":"709152","DOI":"10.1155\/2014\/709152","volume":"2014","author":"M Gupta","year":"2014","unstructured":"Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc therapy in dermatology: a review. Dermatol Res Pract. 2014;2014:709152. \n                    https:\/\/doi.org\/10.1155\/2014\/709152\n                    \n                  .","journal-title":"Dermatol Res Pract."},{"issue":"2","key":"374_CR26","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.jdermsci.2016.08.010","volume":"84","author":"S Hessam","year":"2016","unstructured":"Hessam S, Sand M, Neier NM, Gambichler T, Scholl L, Bechara FG. Combination of oral zinc gluconate and topical triclosan: an anti-inflammatory treatment modality for initial hidradenitis suppurativa. J Dermatol Sci. 2016;84(2):197\u2013202. \n                    https:\/\/doi.org\/10.1016\/j.jdermsci.2016.08.010\n                    \n                  .","journal-title":"J Dermatol Sci"},{"issue":"2","key":"374_CR27","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.jhep.2017.11.006","volume":"68","author":"M Boyle","year":"2018","unstructured":"Boyle M, Masson S, Anstee QM. The bidirectional impacts of alcohol consumption and the metabolic syndrome: cofactors for progressive fatty liver disease. J Hepatol. 2018;68(2):251\u201367. \n                    https:\/\/doi.org\/10.1016\/j.jhep.2017.11.006\n                    \n                  .","journal-title":"J Hepatol"},{"issue":"4","key":"374_CR28","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.jaad.2008.11.911","volume":"60","author":"A Alikhan","year":"2009","unstructured":"Alikhan A, Lynch PJ, Eisen DB. Hidradenitis suppurativa: a comprehensive review. J Am Acad Dermatol. 2009;60(4):539\u201361. \n                    https:\/\/doi.org\/10.1016\/j.jaad.2008.11.911\n                    \n                  .","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"374_CR29","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/ijd.13393","volume":"56","author":"U Wollina","year":"2017","unstructured":"Wollina U, Langner D, Heinig B, Nowak A. Comorbidities, treatment, and outcome in severe anogenital inverse acne (hidradenitis suppurativa): a 15-year single center report. Int J Dermatol. 2017;56(1):109\u201315. \n                    https:\/\/doi.org\/10.1111\/ijd.13393\n                    \n                  .","journal-title":"Int J Dermatol"},{"issue":"2","key":"374_CR30","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.jaad.2017.08.042","volume":"78","author":"TL Bui","year":"2018","unstructured":"Bui TL, Silva-Hirschberg C, Torres J, Armstrong AW. Hidradenitis suppurativa and diabetes mellitus: a systematic review and meta-analysis. J Am Acad Dermatol. 2018;78(2):395\u2013402. \n                    https:\/\/doi.org\/10.1016\/j.jaad.2017.08.042\n                    \n                  .","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"374_CR31","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.jtemb.2012.08.001","volume":"27","author":"J Capdor","year":"2013","unstructured":"Capdor J, Foster M, Petocz P, Samman S. Zinc and glycemic control: a meta-analysis of randomised placebo controlled supplementation trials in humans. J Trace Elem Med Biol. 2013;27(2):137\u201342. \n                    https:\/\/doi.org\/10.1016\/j.jtemb.2012.08.001\n                    \n                  .","journal-title":"J Trace Elem Med Biol"},{"issue":"5 Suppl 1","key":"374_CR32","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1016\/j.jaad.2015.07.054","volume":"73","author":"M Gooderham","year":"2015","unstructured":"Gooderham M, Papp K. The psychosocial impact of hidradenitis suppurativa. J Am Acad Dermatol. 2015;73(5 Suppl 1):S19\u201322. \n                    https:\/\/doi.org\/10.1016\/j.jaad.2015.07.054\n                    \n                  .","journal-title":"J Am Acad Dermatol"},{"key":"374_CR33","doi-asserted-by":"publisher","first-page":"414","DOI":"10.3389\/fphar.2017.00414","volume":"8","author":"MA Petrilli","year":"2017","unstructured":"Petrilli MA, Kranz TM, Kleinhaus K, et al. The emerging role for zinc in depression and psychosis. Front Pharmacol. 2017;8:414. \n                    https:\/\/doi.org\/10.3389\/fphar.2017.00414\n                    \n                  .","journal-title":"Front Pharmacol."},{"key":"374_CR34","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1067\/mlc.2002.123624","volume":"139","author":"GC Sturniolo","year":"2002","unstructured":"Sturniolo GC, Fries W, Mazzon E, et al. Effect of zinc supplementation on intestinal permeability in experimental colitis. J Lab Clin Med. 2002;139:311\u20135.","journal-title":"J Lab Clin Med"},{"key":"374_CR35","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1097\/00054725-200105000-00003","volume":"7","author":"GC Sturniolo","year":"2001","unstructured":"Sturniolo GC, Di Leo V, Ferronato A, et al. Zinc supplementation tightens \u201cleaky gut\u201d in Crohn\u2019s disease. Inflamm Bowel Dis. 2001;7:94\u20138.","journal-title":"Inflamm Bowel Dis"},{"issue":"1","key":"374_CR36","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1097\/MIB.0000000000000989","volume":"23","author":"S Siva","year":"2017","unstructured":"Siva S, Rubin DT, Gulotta G. Zinc deficiency is associated with por clinical outcomes in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2017;23(1):152\u20137.","journal-title":"Inflamm Bowel Dis"}],"container-title":["American Journal of Clinical Dermatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s40257-018-0374-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40257-018-0374-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40257-018-0374-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,23]],"date-time":"2019-07-23T19:14:10Z","timestamp":1563909250000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s40257-018-0374-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,24]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["374"],"URL":"https:\/\/doi.org\/10.1007\/s40257-018-0374-5","relation":{},"ISSN":["1175-0561","1179-1888"],"issn-type":[{"value":"1175-0561","type":"print"},{"value":"1179-1888","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,24]]},"assertion":[{"value":"24 July 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"All cases and control patients enrolled in this study gave informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"The local ethics committee approved this study, which was performed in compliance with the Declaration of Helsinki (CEIC PI2016\/62.1).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"No sources of funding were used to conduct this study or prepare this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"In\u00e9s Poveda, Eva Vilarrasa, Antonio Martorell, Francisco Javier Garc\u00eda-Mart\u00ednez, Juan Manuel Segura, Patricia Hisp\u00e1n, Jos\u00e9 S\u00e1nchez-Pay\u00e1, Pedro Jos\u00e9 \u00c1lvarez, Iris Gonz\u00e1lez and Jose Carlos Pascual declare that they have no conflicts of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}