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In the last 3\u00a0years, Aaron Drucker has been a consultant for Sanofi, RTI Health Solutions, Eczema Society of Canada, and the Canadian Agency for Drugs and Technology in Health. He has received honoraria from Prime Inc., CME Outfitters, and the Eczema Society of Canada. His institution has received educational grants from Sanofi and research grants from Sanofi and Regeneron. Neil Shear is a consultant to AbbVie, Amgen, Bausch Medical, Celgene, Janssen, Leo Pharma, Lilly, Novartis, Sanofi-Genzyme, and Sun Pharma.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest\/Competing Interests"}},{"value":"Not required by our institution for this systematic review.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable, none required by our institution for this systematic review.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable, none required by our institution for this systematic review.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"This systematic review follows Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The data reported in this manuscript were obtained from openly available, previously published articles in the literature found through the PubMed database, and were cited accordingly.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of Data and Material"}},{"value":"Not applicable, no custom code or mathematical algorithm deemed central to the conclusions was used.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}},{"value":"NS, MS and RPD-G made substantial contributions to the design of the work, analysis, interpretation of data, drafting and critical\u00a0revision\u00a0of the work. AMD, NHS and MZ made substantial contributions to the design and critical revision of the work.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 Contributions"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}