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Robin Vos (1803521N) and Tim Vanuytsel (1830517N) are supported by the Research Foundation - Flanders (FWO), Belgium, as Senior Clinical Research Fellows.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Tim Vanuytsel has given scientific advice to VectivBio, Shire, Dr. Falk Pharma, Takeda, and Baxter; has received research support from Danone, MyHealth, and VectivBio; and has served on the speaker bureau for Abbott, Tramedico, Truvion, Will Pharma, My Health, Kyowa Kirin, Menarini, Biocodex, Remedus, Fresenius Kabi, and Dr. Falk Pharma. Robin Vos received consultancy fees from AstraZeneca, GlaxoSmithKline, Takeda, Shionogi, and Zambon. Dirk Kuypers has received financial support from Astellas, Chiesi, and HIKMA. Jef Verbeek has received consultancy fees from Astellas. Erwin Dreesen has received consultancy fees from Alimentiv and Argenx, lecture fees from Galapagos and Celltrion, and financial support from Janssen, Prometheus, and Sandoz, outside the submitted work, with all honoraria\/fees being paid to KU\u00a0Leuven and not to any personal account of Erwin Dreesen. All authors have no conflicts of interest that are directly relevant to the content of this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"Not applicable.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of Data and Material"}},{"value":"The model code that supports the findings of this study is available from the corresponding author upon reasonable request.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}},{"value":"Conceptualization: YH and ED; data curation: YH; formal analysis: YH; funding acquisition: YH; investigation: YH; methodology: YH and ED; project administration: YH and ED; resources: ED; software: YH; supervision: ED; validation: ND, TV, RV, DK, JVC, and JV; visualization: YH; writing\u2014original draft: YH; writing\u2014review and editing: YH, ND, TV, RV, DK, JVC, JV, and ED.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 Contributions"}}]}}