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The other authors have no competing interests to declare that are relevant to the content of this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The datasets generated during the current study are available from the corresponding author upon reasonable request.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data and materials"}},{"value":"Alexandra-Maria Stommel: conceptualization, validation, formal analysis, investigation, data curation, writing\u2014original draft, writing\u2014review and editing, and visualization. Peter Matzneller: conceptualization, investigation, and writing\u2014review and editing. Valentin al Jalali: formal analysis, data curation, visualization, and writing\u2014review and editing. Beatrix Wulkersdorfer: investigation, data curation, writing\u2014review and editing, and project administration. Edith Lackner: investigation, writing\u2014review and editing, and project administration. Matthias Mueller: investigation and writing\u2014review and editing. Christoph Dorn: methodology, validation, formal analysis, investigation, resources, data curation, and writing\u2014review and editing. Michael Holzer: writing\u2014review and editing and supervision. Markus Zeitlinger: conceptualization, methodology, validation, resources, writing\u2014review and editing, supervision, project administration, and funding acquisition.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author contributions"}},{"value":"The study was approved by the ethics committee of the Medical University of Vienna, Austria (EC: 1348\/2015) and the Austrian Agency for Health and Food Safety. It was registered in the European Union Drug Regulating Authorities Clinical Trials Database (EUDRACT 2015-001793-18) and conducted according to International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use good clinical practice guidelines and the Declaration of Helsinki.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Since the participants were unconscious, informed written consent was obtained from survivors once they were able to comprehend the study. The treating team informed patients\u2019 relatives about their inclusion in the study, but the ethics committee did not mandate this as a requirement.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Not applicable.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}}]}}